Cblc Rat Gene (Cas-Br-M (murine) ecotropic retroviral transforming sequence c)

Help | FTP Download | Citing RGD | Contact Us

Keyword

Gene:
Cblc ( Rattus norvegicus )
Cas-Br-M (murine) ecotropic retroviral transforming sequence c
Description: exhibits protine binding, zinc ion binding; involved in negative regulation of epidermal growth factor receptor activity and protein amino acid phosphorylation (homolog)
Synonyms: Casitas B-lineage lymphoma c (predicted); Cblc_predicted; Casitas B-lineage lymphoma c; MGC124804; LOC292699;  (details...)
ArrayIDs: 6590422; 5851683; 6418368; GE1283125; 5880954; rc_AI071496_at; 6568139; 5659024; 1378550_at; 5642568; 6452142; 5956717; 6319673; 6638229; 6566064; 6189005; 5778272; A_44_P456923; 6620257;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: CBLC     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Cblc     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Cblc genome assembly 3.1 1 79170940 - 79186278
Rat Celera Assembly 1 73898303 - 73914934
RGSC genome assembly v3.4 1 79091412 - 79108174
Cytogenetic 1 q21
Mus musculus Cblc Mouse genome assembly build 36.1 7 20365069 - 20382158
Cytogenetic 7 7 A3
Homo sapiens CBLC human genome assembly 19 49972987 - 49995731
Human genome assembly build 36.2 19 49972988 - 49995731
Cytogenetic 19 q13.2

View comparative maps:      NCBI MapViewer

Genome
View:

Browsers:

Annotation
Molecular Function

Gene Ontology

zinc ion binding,  ubiquitin-protein ligase activity,  signal transducer activity ... (details...)
Biological Process

Gene Ontology

negative regulation of epidermal growth factor receptor activity,  negative regulation of MAP kinase activity,  protein ubiquitination during ubiquitin-dependent protein catabolic process ... (details...)
Cellular Component

Gene Ontology

nucleus (details...)

External Links
Databases
DATABASE ID SOURCE
SMART: RING IPI
PROSITE: ZF_RING_2 IPI
PROSITE: ZF_RING_1 IPI
UNIPARC: UPI00005C8B68 IPI
UNIPARC: UPI000154EA49 IPI
KEGG Report: rno:292699 ENTREZGENE
HomoloGene Group ID: 8108 ENTREZGENE
Germonline: 1307651
Pfam: Cbl_N3 IPI
Pfam: zf-C3HC4 IPI
Pfam: Cbl_N2 IPI
Pfam: Cbl_N IPI
KEGG Pathway: 05220 ENTREZGENE
KEGG Pathway: 04012 ENTREZGENE
KEGG Pathway: 04910 ENTREZGENE
KEGG Pathway: 04630 ENTREZGENE
KEGG Pathway: 04144 ENTREZGENE
KEGG Pathway: 04120 ENTREZGENE
KEGG Pathway: 04660 ENTREZGENE
KEGG Pathway: 05200 ENTREZGENE
InterPro: Adaptor_Cbl_N. IPI
InterPro: Znf_RING_CS. IPI
InterPro: Znf_RING/FYVE/PHD. IPI
InterPro: Znf_C3HC4_RING-type. IPI
InterPro: SH2. IPI
InterPro: EF-Hand_type. IPI
InterPro: Adaptor_Cbl_SH2-like. IPI
InterPro: Znf_RING. IPI
InterPro: Adaptor_Cbl_EF_Hand-like. IPI
IPI: IPI00951022 IPI
IPI: IPI00364049 IPI
Ensembl Protein: ENSRNOP00000061850 IPI
Ensembl Protein: ENSRNOP00000025829 IPI
Gene3D-CATH: EF-Hand_type IPI
Gene3D-CATH: Adaptor_Cbl_N IPI
Gene3D-CATH: SH2 IPI
Gene3D-CATH: Znf_RING/FYVE/PHD IPI
Entrez Gene: Cblc ENTREZGENE
IMAGE_CLONE: IMAGE:7931977 IMAGE-MGC_LOAD
MGC_CLONE: MGC:124804 IMAGE-MGC_LOAD
UniProt: Q3KRC9_RAT IPI
Ensembl Genes: ENSRNOG00000018953 IPI
Superfamily-SCOP: Adaptor_Cbl_N IPI
Sequences
Nucleotide: CH473979 Get FASTA Search GEO Profiles
Nucleotide: BC105776 Get FASTA Search GEO Profiles
Nucleotide: NM_001034920 Get FASTA Search GEO Profiles
Nucleotide: DN934498 Get FASTA Search GEO Profiles
(View all 4 Nucleotide Accessions)
Protein: NP_001030092 Get FASTA
Protein: EDM08130 Get FASTA
Protein: EDM08131 Get FASTA
Protein: EDM08132 Get FASTA
Protein: EDM08133 Get FASTA
Protein: EDM08134 Get FASTA
Protein: EDM08135 Get FASTA
Protein: AAI05777 Get FASTA
Protein: Q3KRC9 Get FASTA
(View all 9 Protein Accessions)
Clusters
UniGene: 20550

References
Curated References
2 references in RGD related to Cblc

Other References
2 other references at PubMed related to Cblc

Database Information
RGD ID 1307651
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

18-SEP-08: Cblc Cas-Br-M (murine) ecotropic retroviral transforming sequence c Cblc Casitas B-lineage lymphoma c APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

06-DEC-05: Cblc Casitas B-lineage lymphoma c Cblc_predicted Casitas B-lineage lymphoma c (predicted) APPROVED Symbol and Name updated 1559027

12-JAN-05: Cblc_predicted Casitas B-lineage lymphoma c (predicted) APPROVED Symbol and Name status set to approved 70820