Cfap70 (cilia and flagella associated protein 70) - Rat Genome Database

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Gene: Cfap70 (cilia and flagella associated protein 70) Rattus norvegicus
Analyze
Symbol: Cfap70
Name: cilia and flagella associated protein 70
RGD ID: 1307577
Description: Predicted to be involved in cilium assembly and cilium movement. Predicted to act upstream of or within several processes, including maintenance of cell number; single fertilization; and spermatid development. Predicted to be located in axoneme; ciliary basal body; and sperm flagellum. Predicted to be part of outer dynein arm. Predicted to be active in cytoplasm; manchette; and motile cilium. Human ortholog(s) of this gene implicated in spermatogenic failure 41. Orthologous to human CFAP70 (cilia and flagella associated protein 70); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cilia- and flagella-associated protein 70; LOC361006; tetratricopeptide repeat domain 18; tetratricopeptide repeat protein 18; Ttc18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8153,901,544 - 3,967,224 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl153,901,610 - 3,967,220 (+)EnsemblGRCr8
mRatBN7.2153,852,381 - 3,918,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl153,852,509 - 3,918,014 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx153,862,663 - 3,928,143 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,249,087 - 5,314,568 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,861,481 - 3,926,964 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,285,049 - 4,350,707 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,285,052 - 4,350,714 (+)Ensemblrn6Rnor6.0
Rnor_5.0158,386,331 - 8,452,205 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4154,079,765 - 4,112,202 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera15677,033 - 742,609 (-)NCBICelera
RGSC_v3.1154,083,325 - 4,148,781 (+)NCBI
Cytogenetic Map15p16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axonemal central apparatus  (IEA,ISO)
axoneme  (IEA,ISO)
ciliary basal body  (ISO)
cytoplasm  (IEA,ISO)
manchette  (IEA,ISO)
motile cilium  (IBA,IEA,ISO)
outer dynein arm  (ISO)
sperm flagellum  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19056867   PMID:30158508   PMID:31621862  


Genomics

Comparative Map Data
Cfap70
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8153,901,544 - 3,967,224 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl153,901,610 - 3,967,220 (+)EnsemblGRCr8
mRatBN7.2153,852,381 - 3,918,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl153,852,509 - 3,918,014 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx153,862,663 - 3,928,143 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,249,087 - 5,314,568 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,861,481 - 3,926,964 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,285,049 - 4,350,707 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,285,052 - 4,350,714 (+)Ensemblrn6Rnor6.0
Rnor_5.0158,386,331 - 8,452,205 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4154,079,765 - 4,112,202 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera15677,033 - 742,609 (-)NCBICelera
RGSC_v3.1154,083,325 - 4,148,781 (+)NCBI
Cytogenetic Map15p16NCBI
CFAP70
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381073,253,762 - 73,362,979 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1073,253,762 - 73,358,864 (-)Ensemblhg38GRCh38
GRCh371075,013,520 - 75,118,622 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361074,683,526 - 74,788,618 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341074,683,529 - 74,788,618NCBI
Celera1068,299,139 - 68,404,237 (-)NCBICelera
Cytogenetic Map10q22.2NCBI
HuRef1069,007,376 - 69,112,474 (-)NCBIHuRef
CHM1_11075,295,233 - 75,400,378 (-)NCBICHM1_1
T2T-CHM13v2.01074,125,143 - 74,236,682 (-)NCBIT2T-CHM13v2.0
Cfap70
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,444,258 - 20,502,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1420,444,261 - 20,502,294 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381420,394,190 - 20,452,264 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,394,193 - 20,452,226 (-)Ensemblmm10GRCm38
MGSCv371421,213,412 - 21,271,447 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361419,182,745 - 19,240,774 (-)NCBIMGSCv36mm8
Celera1416,775,029 - 16,833,441 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.53NCBI
Cfap70
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543718,426,317 - 18,480,297 (+)Ensembl
ChiLan1.0NW_00495543718,424,568 - 18,480,327 (+)NCBIChiLan1.0ChiLan1.0
CFAP70
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2885,429,689 - 85,535,071 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11085,435,012 - 85,540,394 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01069,801,407 - 69,906,688 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11072,260,229 - 72,364,848 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1072,260,229 - 72,360,714 (-)EnsemblpanPan2panpan1.1
CFAP70
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1423,830,335 - 23,926,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl423,830,336 - 23,924,350 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha423,968,485 - 24,064,708 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0424,111,719 - 24,207,085 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl424,111,720 - 24,204,484 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1424,009,301 - 24,104,612 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0424,208,588 - 24,305,064 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0424,564,592 - 24,659,955 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cfap70
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721357,188,073 - 57,292,057 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365215,684,224 - 5,784,714 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365215,680,846 - 5,785,818 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFAP70
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1476,075,275 - 76,198,778 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11476,075,269 - 76,199,898 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21482,200,158 - 82,324,346 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CFAP70
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1957,917,170 - 58,019,298 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl957,930,772 - 58,019,372 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604818,499,595 - 18,603,712 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cfap70
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247546,923,632 - 6,973,670 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247546,923,431 - 6,977,007 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cfap70
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11290,194,463 - 90,254,759 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cfap70
209 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:84
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000009332, ENSRNOT00000035303, ENSRNOT00000035345
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15115177511Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 165 91 90 59 92 59 6 355 191 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003751430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003752779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005493747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ150649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000035345   ⟹   ENSRNOP00000030551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl153,901,614 - 3,967,202 (+)Ensembl
mRatBN7.2 Ensembl153,852,509 - 3,918,014 (+)Ensembl
Rnor_6.0 Ensembl154,285,052 - 4,350,714 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111064   ⟹   ENSRNOP00000095268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl153,901,614 - 3,967,202 (+)Ensembl
mRatBN7.2 Ensembl153,852,509 - 3,918,014 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114948   ⟹   ENSRNOP00000091914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl153,901,610 - 3,967,220 (+)Ensembl
mRatBN7.2 Ensembl153,852,509 - 3,918,014 (+)Ensembl
RefSeq Acc Id: NM_001108370   ⟹   NP_001101840
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,733 - 3,967,224 (+)NCBI
mRatBN7.2153,852,509 - 3,918,036 (+)NCBI
RefSeq Acc Id: XM_006251665   ⟹   XP_006251727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,544 - 3,967,224 (+)NCBI
mRatBN7.2153,852,389 - 3,918,036 (+)NCBI
Rnor_6.0154,285,049 - 4,350,707 (+)NCBI
Rnor_5.0158,386,331 - 8,452,205 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251666   ⟹   XP_006251728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,598 - 3,967,224 (+)NCBI
mRatBN7.2153,852,381 - 3,918,036 (+)NCBI
Rnor_6.0154,285,065 - 4,350,707 (+)NCBI
Rnor_5.0158,386,331 - 8,452,205 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251667   ⟹   XP_006251729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,598 - 3,967,224 (+)NCBI
mRatBN7.2153,852,382 - 3,918,036 (+)NCBI
Rnor_6.0154,285,065 - 4,350,707 (+)NCBI
Rnor_5.0158,386,331 - 8,452,205 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093437   ⟹   XP_038949365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,597 - 3,963,899 (+)NCBI
mRatBN7.2153,852,381 - 3,913,570 (+)NCBI
RefSeq Acc Id: XM_039093438   ⟹   XP_038949366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,918,861 - 3,967,224 (+)NCBI
mRatBN7.2153,871,598 - 3,918,036 (+)NCBI
RefSeq Acc Id: XM_039093439   ⟹   XP_038949367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,597 - 3,952,490 (+)NCBI
mRatBN7.2153,852,381 - 3,903,297 (+)NCBI
RefSeq Acc Id: XM_039093440   ⟹   XP_038949368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,920,943 - 3,967,224 (+)NCBI
mRatBN7.2153,871,601 - 3,918,036 (+)NCBI
RefSeq Acc Id: XM_039093441   ⟹   XP_038949369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,921,485 - 3,967,224 (+)NCBI
mRatBN7.2153,872,286 - 3,918,036 (+)NCBI
RefSeq Acc Id: XM_039093442   ⟹   XP_038949370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,933,224 - 3,967,224 (+)NCBI
mRatBN7.2153,884,013 - 3,918,036 (+)NCBI
RefSeq Acc Id: XM_039093443   ⟹   XP_038949371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,932,423 - 3,967,224 (+)NCBI
mRatBN7.2153,883,231 - 3,918,036 (+)NCBI
RefSeq Acc Id: XM_063274374   ⟹   XP_063130444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,544 - 3,967,224 (+)NCBI
RefSeq Acc Id: XM_063274375   ⟹   XP_063130445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,544 - 3,967,224 (+)NCBI
RefSeq Acc Id: XM_063274376   ⟹   XP_063130446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,594 - 3,967,224 (+)NCBI
RefSeq Acc Id: XM_063274377   ⟹   XP_063130447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,544 - 3,967,224 (+)NCBI
RefSeq Acc Id: XM_063274378   ⟹   XP_063130448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,928,234 - 3,967,224 (+)NCBI
RefSeq Acc Id: XM_063274379   ⟹   XP_063130449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,597 - 3,947,987 (+)NCBI
RefSeq Acc Id: XR_005493747
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,598 - 3,966,475 (+)NCBI
mRatBN7.2153,852,381 - 3,917,284 (+)NCBI
RefSeq Acc Id: XR_010057834
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,901,598 - 3,966,475 (+)NCBI
RefSeq Acc Id: XP_006251728   ⟸   XM_006251666
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AND1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251729   ⟸   XM_006251667
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AH20 (UniProtKB/TrEMBL),   A0A8I6AND1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251727   ⟸   XM_006251665
- Peptide Label: isoform X1
- UniProtKB: D4A513 (UniProtKB/TrEMBL),   A0A8I6AND1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030551   ⟸   ENSRNOT00000035345
RefSeq Acc Id: XP_038949365   ⟸   XM_039093437
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AND1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949367   ⟸   XM_039093439
- Peptide Label: isoform X7
RefSeq Acc Id: NP_001101840   ⟸   NM_001108370
- UniProtKB: D4A513 (UniProtKB/TrEMBL),   A0A8I6AND1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949366   ⟸   XM_039093438
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038949368   ⟸   XM_039093440
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038949369   ⟸   XM_039093441
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038949371   ⟸   XM_039093443
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038949370   ⟸   XM_039093442
- Peptide Label: isoform X11
Ensembl Acc Id: ENSRNOP00000091914   ⟸   ENSRNOT00000114948
Ensembl Acc Id: ENSRNOP00000095268   ⟸   ENSRNOT00000111064
RefSeq Acc Id: XP_063130444   ⟸   XM_063274374
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AND1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130445   ⟸   XM_063274375
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AH20 (UniProtKB/TrEMBL),   A0A8I6AND1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130447   ⟸   XM_063274377
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AND1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130446   ⟸   XM_063274376
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AND1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130449   ⟸   XM_063274379
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063130448   ⟸   XM_063274378
- Peptide Label: isoform X9

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A513-F1-model_v2 AlphaFold D4A513 1-1141 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699568
Promoter ID:EPDNEW_R10089
Type:initiation region
Name:Cfap70_1
Description:cilia and flagella associated protein 70
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0154,285,074 - 4,285,134EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307577 AgrOrtholog
BioCyc Gene G2FUF-14537 BioCyc
Ensembl Genes ENSRNOG00000007046 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035345 ENTREZGENE
  ENSRNOT00000035345.9 UniProtKB/TrEMBL
  ENSRNOT00000111064.2 UniProtKB/TrEMBL
  ENSRNOT00000114948 ENTREZGENE
  ENSRNOT00000114948.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro CFAP70 UniProtKB/TrEMBL
  TPR-like_helical UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene 361006 ENTREZGENE
PANTHER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 UniProtKB/TrEMBL
  CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 UniProtKB/TrEMBL
Pfam TPR_8 UniProtKB/TrEMBL
PhenoGen Cfap70 PhenoGen
PROSITE TPR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007046 RatGTEx
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8I6AH20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AND1 ENTREZGENE, UniProtKB/TrEMBL
  D4A513 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-11 Cfap70  cilia and flagella associated protein 70  Ttc18  tetratricopeptide repeat domain 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ttc18  tetratricopeptide repeat domain 18   Ttc18_predicted  tetratricopeptide repeat domain 18 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ttc18_predicted  tetratricopeptide repeat domain 18 (predicted)      Symbol and Name status set to approved 70820 APPROVED