Zfp330 (zinc finger protein 330) - Rat Genome Database

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Gene: Zfp330 (zinc finger protein 330) Rattus norvegicus
Analyze
Symbol: Zfp330
Name: zinc finger protein 330
RGD ID: 1307510
Description: Predicted to enable zinc ion binding activity. Predicted to be located in chromosome, centromeric region and midbody. Predicted to be active in nucleus. Orthologous to human ZNF330 (zinc finger protein 330); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC103694300; LOC361387; uncharacterized LOC103694300
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81942,218,213 - 42,229,516 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1942,205,549 - 42,229,516 (+)EnsemblGRCr8
mRatBN7.21925,313,655 - 25,324,958 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1925,313,655 - 25,324,958 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1932,155,739 - 32,167,025 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01932,809,802 - 32,821,088 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01935,025,264 - 35,036,550 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01923,936,522 - 23,946,900 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1923,936,505 - 23,946,900 (-)Ensemblrn6Rnor6.0
Rnor_5.01934,916,045 - 34,926,423 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41927,048,575 - 27,059,878 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1924,853,332 - 24,864,637 (+)NCBICelera
RGSC_v3.11927,028,736 - 27,064,683 (+)NCBI
Cytogenetic Map19q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome, centromeric region  (IEA,ISO)
midbody  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10593942  


Genomics

Comparative Map Data
Zfp330
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81942,218,213 - 42,229,516 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1942,205,549 - 42,229,516 (+)EnsemblGRCr8
mRatBN7.21925,313,655 - 25,324,958 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1925,313,655 - 25,324,958 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1932,155,739 - 32,167,025 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01932,809,802 - 32,821,088 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01935,025,264 - 35,036,550 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01923,936,522 - 23,946,900 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1923,936,505 - 23,946,900 (-)Ensemblrn6Rnor6.0
Rnor_5.01934,916,045 - 34,926,423 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41927,048,575 - 27,059,878 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1924,853,332 - 24,864,637 (+)NCBICelera
RGSC_v3.11927,028,736 - 27,064,683 (+)NCBI
Cytogenetic Map19q11NCBI
ZNF330
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384141,220,535 - 141,234,697 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4141,220,280 - 141,234,697 (+)Ensemblhg38GRCh38
GRCh374142,142,049 - 142,155,851 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364142,361,547 - 142,375,301 (+)NCBIBuild 36Build 36hg18NCBI36
Build 344142,499,701 - 142,513,453NCBI
Celera4139,472,797 - 139,486,599 (+)NCBICelera
Cytogenetic Map4q31.21NCBI
HuRef4137,871,686 - 137,885,488 (+)NCBIHuRef
CHM1_14142,119,447 - 142,133,249 (+)NCBICHM1_1
T2T-CHM13v2.04144,540,345 - 144,554,401 (+)NCBIT2T-CHM13v2.0
Zfp330
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39883,490,247 - 83,500,774 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl883,490,236 - 83,500,789 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38882,763,618 - 82,774,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl882,763,607 - 82,774,160 (-)Ensemblmm10GRCm38
MGSCv37885,287,519 - 85,298,025 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36885,653,725 - 85,664,231 (-)NCBIMGSCv36mm8
Celera887,063,097 - 87,073,634 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map839.58NCBI
Znf330
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554711,933,451 - 1,947,124 (-)Ensembl
ChiLan1.0NW_0049554711,933,675 - 1,946,572 (-)NCBIChiLan1.0ChiLan1.0
ZNF330
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23139,093,924 - 139,109,748 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14139,481,076 - 139,496,887 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04133,580,533 - 133,594,798 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14144,883,845 - 144,898,126 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4144,884,319 - 144,898,126 (+)EnsemblpanPan2panpan1.1
ZNF330
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1191,730,999 - 1,752,877 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl191,731,641 - 1,752,772 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha191,977,100 - 1,999,196 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0191,791,507 - 1,815,292 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl191,791,509 - 1,815,242 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1191,732,486 - 1,754,555 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0192,093,325 - 2,115,440 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0192,449,431 - 2,471,426 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znf330
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530149,306,839 - 49,319,715 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365356,744,876 - 6,755,930 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365356,744,179 - 6,757,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF330
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl886,019,115 - 86,036,201 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1886,019,111 - 86,036,738 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2891,327,714 - 91,340,812 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF330
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1788,133,603 - 88,146,584 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl788,133,623 - 88,147,303 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603767,666,255 - 67,679,468 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf330
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624853621,675 - 637,130 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624853622,392 - 634,696 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Znf330
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11717,436,113 - 17,447,059 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zfp330
116 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:49
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000004614
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)194172060949971820Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat

Markers in Region
RH129701  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21925,324,741 - 25,324,891 (-)MAPPERmRatBN7.2
Rnor_6.01923,936,589 - 23,936,738NCBIRnor6.0
Rnor_5.01934,916,112 - 34,916,261UniSTSRnor5.0
RGSC_v3.41927,059,662 - 27,059,811UniSTSRGSC3.4
Celera1924,864,421 - 24,864,570UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004614   ⟹   ENSRNOP00000004614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1942,217,457 - 42,229,516 (+)Ensembl
mRatBN7.2 Ensembl1925,313,655 - 25,324,958 (+)Ensembl
Rnor_6.0 Ensembl1923,936,522 - 23,946,900 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080337   ⟹   ENSRNOP00000071964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1923,936,505 - 23,944,820 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000128080   ⟹   ENSRNOP00000111567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1942,218,547 - 42,229,502 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000137201   ⟹   ENSRNOP00000110468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1942,205,549 - 42,229,516 (+)Ensembl
RefSeq Acc Id: NM_001108443   ⟹   NP_001101913
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81942,218,213 - 42,229,516 (+)NCBI
mRatBN7.21925,313,655 - 25,324,958 (+)NCBI
Rnor_6.01923,936,522 - 23,946,900 (-)NCBI
Rnor_5.01934,916,045 - 34,926,423 (-)NCBI
RGSC_v3.41927,048,575 - 27,059,878 (+)RGD
Celera1924,853,332 - 24,864,637 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101913 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004614.6
  ENSRNOP00000110468.1
  ENSRNOP00000111567
  ENSRNOP00000111567.1
RefSeq Acc Id: NP_001101913   ⟸   NM_001108443
- UniProtKB: D3ZSN4 (UniProtKB/TrEMBL),   A6IYG0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071964   ⟸   ENSRNOT00000080337
Ensembl Acc Id: ENSRNOP00000004614   ⟸   ENSRNOT00000004614
Ensembl Acc Id: ENSRNOP00000110468   ⟸   ENSRNOT00000137201
Ensembl Acc Id: ENSRNOP00000111567   ⟸   ENSRNOT00000128080

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSN4-F1-model_v2 AlphaFold D3ZSN4 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700994
Promoter ID:EPDNEW_R11517
Type:multiple initiation site
Name:Zfp330_1
Description:zinc finger protein 330
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01923,946,633 - 23,946,693EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307510 AgrOrtholog
BioCyc Gene G2FUF-5992 BioCyc
Ensembl Genes ENSRNOG00000003461 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004614.7 UniProtKB/TrEMBL
  ENSRNOT00000128080 ENTREZGENE
  ENSRNOT00000128080.1 UniProtKB/TrEMBL
  ENSRNOT00000137201.1 UniProtKB/TrEMBL
InterPro NOA36 UniProtKB/TrEMBL
KEGG Report rno:361387 UniProtKB/TrEMBL
NCBI Gene 361387 ENTREZGENE
PANTHER NOA36 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 330 UniProtKB/TrEMBL
Pfam NOA36 UniProtKB/TrEMBL
PhenoGen Zfp330 PhenoGen
RatGTEx ENSRNOG00000003461 RatGTEx
UniProt A0ABK0LYT7_RAT UniProtKB/TrEMBL
  A0ABK0M7R6_RAT UniProtKB/TrEMBL
  A6IYG0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSN4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Zfp330  zinc finger protein 330  LOC103694300  uncharacterized LOC103694300  Data merged from RGD:9098364 737654 PROVISIONAL
2014-08-25 LOC103694300  uncharacterized LOC103694300      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Zfp330  zinc finger protein 330   Zfp330_predicted  zinc finger protein 330 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Zfp330_predicted  zinc finger protein 330 (predicted)      Symbol and Name status set to approved 70820 APPROVED