Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pip4p1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pip4p1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PIP4P1 mRNA | CTD | PMID:21570461 | Pip4p1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PIP4P1 mRNA | CTD | PMID:33387578 | Pip4p1 | Rat | 2-hydroxypropanoic acid | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PIP4P1 mRNA | CTD | PMID:30851411 | Pip4p1 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Pip4p1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PIP4P1 mRNA | CTD | PMID:20188158 | Pip4p1 | Rat | all-trans-retinoic acid | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PIP4P1 mRNA | CTD | PMID:33167477 | Pip4p1 | Rat | arsenous acid | multiple interactions | ISO | PIP4P1 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PIP4P1 protein] | CTD | PMID:26598702 | Pip4p1 | Rat | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA | CTD | PMID:33854195 | Pip4p1 | Rat | benzo[a]pyrene | multiple interactions | ISO | Pip4p1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PIP4P1 mRNA | CTD | PMID:27858113 | Pip4p1 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | Pip4p1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PIP4P1 mRNA | CTD | PMID:27858113 | Pip4p1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PIP4P1 mRNA | CTD | PMID:25181051 | Pip4p1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PIP4P1 mRNA | CTD | PMID:34947998 | Pip4p1 | Rat | bisphenol A | increases expression | ISO | Pip4p1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PIP4P1 mRNA | CTD | PMID:33221593 | Pip4p1 | Rat | bortezomib | decreases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of PIP4P1 mRNA | CTD | PMID:20977926 | Pip4p1 | Rat | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA | CTD | PMID:33854195 | Pip4p1 | Rat | chlorpyrifos | increases expression | ISO | Pip4p1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of PIP4P1 mRNA | CTD | PMID:37019170 | Pip4p1 | Rat | chromium(6+) | affects expression | ISO | Pip4p1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of PIP4P1 mRNA | CTD | PMID:28472532 | Pip4p1 | Rat | chrysene | multiple interactions | ISO | Pip4p1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PIP4P1 mRNA | CTD | PMID:27858113 | Pip4p1 | Rat | coumarin | increases phosphorylation | ISO | PIP4P1 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of PIP4P1 protein | CTD | PMID:35688186 | Pip4p1 | Rat | cyclosporin A | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PIP4P1 mRNA | CTD | PMID:20106945 | Pip4p1 | Rat | DDE | decreases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of PIP4P1 mRNA | CTD | PMID:38568856 | Pip4p1 | Rat | diarsenic trioxide | multiple interactions | ISO | PIP4P1 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PIP4P1 protein] | CTD | PMID:26598702 | Pip4p1 | Rat | Dibutyl phosphate | affects expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of PIP4P1 mRNA | CTD | PMID:37042841 | Pip4p1 | Rat | doxorubicin | decreases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PIP4P1 mRNA | CTD | PMID:29803840 | Pip4p1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of PIP4P1 mRNA | CTD | PMID:29391264 and PMID:31464424 | Pip4p1 | Rat | ethanol | affects splicing | ISO | Pip4p1 (Mus musculus) | 6480464 | Ethanol affects the splicing of PIP4P1 mRNA | CTD | PMID:30319688 | Pip4p1 | Rat | fluoxetine | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Fluoxetine results in increased expression of PIP4P1 mRNA | CTD | PMID:37386098 | Pip4p1 | Rat | FR900359 | decreases phosphorylation | ISO | PIP4P1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of PIP4P1 protein | CTD | PMID:37730182 | Pip4p1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PIP4P1 mRNA | CTD | PMID:33387578 | Pip4p1 | Rat | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA | CTD | PMID:33854195 | Pip4p1 | Rat | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA | CTD | PMID:33854195 | Pip4p1 | Rat | ivermectin | decreases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PIP4P1 protein | CTD | PMID:32959892 | Pip4p1 | Rat | leflunomide | decreases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of PIP4P1 mRNA | CTD | PMID:28988120 | Pip4p1 | Rat | methyl methanesulfonate | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PIP4P1 mRNA | CTD | PMID:23649840 | Pip4p1 | Rat | paracetamol | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PIP4P1 mRNA | CTD | PMID:22230336 | Pip4p1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PIP4P1 mRNA | CTD | PMID:33387578 | Pip4p1 | Rat | paraquat | affects splicing | ISO | Pip4p1 (Mus musculus) | 6480464 | Paraquat affects the splicing of PIP4P1 exon | CTD | PMID:27111068 | Pip4p1 | Rat | perfluorooctanoic acid | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of PIP4P1 protein | CTD | PMID:26879310 | Pip4p1 | Rat | rac-lactic acid | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PIP4P1 mRNA | CTD | PMID:30851411 | Pip4p1 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of PIP4P1 mRNA | CTD | PMID:28374803 | Pip4p1 | Rat | sodium arsenite | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PIP4P1 mRNA | CTD | PMID:38568856 | Pip4p1 | Rat | sodium arsenite | increases expression | ISO | Pip4p1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of PIP4P1 protein | CTD | PMID:29044176 | Pip4p1 | Rat | sunitinib | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PIP4P1 mRNA | CTD | PMID:31533062 | Pip4p1 | Rat | temozolomide | decreases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of PIP4P1 mRNA | CTD | PMID:31758290 | Pip4p1 | Rat | tetraphene | multiple interactions | ISO | Pip4p1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PIP4P1 mRNA | CTD | PMID:27858113 | Pip4p1 | Rat | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA | CTD | PMID:33854195 | Pip4p1 | Rat | thiram | increases expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | Thiram results in increased expression of PIP4P1 mRNA | CTD | PMID:38568856 | Pip4p1 | Rat | titanium dioxide | increases methylation | ISO | Pip4p1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of PIP4P1 promoter | CTD | PMID:35295148 | Pip4p1 | Rat | titanium dioxide | decreases methylation | ISO | Pip4p1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PIP4P1 gene | CTD | PMID:35295148 | Pip4p1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PIP4P1 mRNA | CTD | PMID:33387578 | Pip4p1 | Rat | triphenyl phosphate | affects expression | ISO | PIP4P1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PIP4P1 mRNA | CTD | PMID:37042841 | Pip4p1 | Rat | triptonide | decreases expression | ISO | Pip4p1 (Mus musculus) | 6480464 | triptonide results in decreased expression of PIP4P1 mRNA | CTD | PMID:33045310 | Pip4p1 | Rat | zinc atom | multiple interactions | ISO | PIP4P1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PIP4P1 mRNA | CTD | PMID:18593933 | Pip4p1 | Rat | zinc(0) | multiple interactions | ISO | PIP4P1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PIP4P1 mRNA | CTD | PMID:18593933 | |