Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBXN4 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Ubxn4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UBXN4 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of UBXN4 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Ubxn4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBXD2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of UBXD2 mRNA | CTD | PMID:17942748 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ubxn4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBXD2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBXN4 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of UBXN4 mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | increases phosphorylation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased phosphorylation of UBXN4 protein | CTD | PMID:23298284 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of UBXD2 mRNA | CTD | PMID:21346803 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of UBXN4 gene | CTD | PMID:31601247 | 4,4'-sulfonyldiphenol | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of UBXN4 protein | CTD | PMID:34186270 | aristolochic acid A | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of UBXN4 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of UBXD2 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of UBXN4 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of UBXN4 mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of UBXN4 protein | CTD | PMID:34186270 | bisphenol A | decreases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of UBXN4 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of UBXN4 mRNA | CTD | PMID:25181051 more ... | Bisphenol B | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of UBXN4 protein | CTD | PMID:34186270 | bortezomib | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of UBXN4 mRNA | CTD | PMID:20977926 | butanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | butyraldehyde results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | caffeine | increases phosphorylation | ISO | UBXN4 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of UBXN4 protein | CTD | PMID:35688186 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of UBXN4 mRNA | CTD | PMID:23125180 | ciguatoxin CTX1B | affects expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of UBXD2 mRNA | CTD | PMID:18353800 | clobetasol | decreases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of UBXN4 mRNA | CTD | PMID:27462272 | cobalt dichloride | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of UBXD2 mRNA | CTD | PMID:19376846 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of UBXN4 mRNA | CTD | PMID:24386269 | copper(II) sulfate | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of UBXN4 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of UBXD2 mRNA | CTD | PMID:20106945 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of UBXN4 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of UBXN4 mRNA | CTD | PMID:28302478 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of UBXN4 mRNA | CTD | PMID:36653537 | elemental selenium | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Selenium results in decreased expression of UBXD2 mRNA | CTD | PMID:19244175 | elemental selenium | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of UBXD2 mRNA | CTD | PMID:19244175 | enzyme inhibitor | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of UBXN4 protein | CTD | PMID:23301498 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of UBXN4 mRNA | CTD | PMID:24136188 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of UBXN4 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of UBXN4 mRNA | CTD | PMID:25629700 | FR900359 | decreases phosphorylation | ISO | UBXN4 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of UBXN4 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of UBXD2 mRNA and Gentamicins results in increased expression of UBXN4 mRNA | CTD | PMID:22061828 and PMID:33387578 | heptanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | heptanal results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | hexanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | n-hexanal results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | hydralazine | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of UBXD2 mRNA | CTD | PMID:17183730 | inulin | multiple interactions | ISO | Ubxn4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of UBXN4 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of UBXN4 protein | CTD | PMID:32959892 | methotrexate | affects expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Methotrexate affects the expression of UBXD2 mRNA | CTD | PMID:18502557 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of UBXN4 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of UBXN4 mRNA | CTD | PMID:24136188 | nonanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | nonanal results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | octanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | caprylic aldehyde results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | paracetamol | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of UBXN4 mRNA | CTD | PMID:26690555 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of UBXN4 mRNA | CTD | PMID:33387578 | pentanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | pentanal results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ubxn4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UBXN4 mRNA more ... | CTD | PMID:36331819 | propanal | increases methylation | ISO | UBXN4 (Homo sapiens) | 6480464 | propionaldehyde results in increased methylation of UBXN4 gene | CTD | PMID:30002397 | resveratrol | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of UBXN4 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of UBXN4 mRNA | CTD | PMID:29955902 | selenium atom | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Selenium results in decreased expression of UBXD2 mRNA | CTD | PMID:19244175 | selenium atom | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of UBXD2 mRNA | CTD | PMID:19244175 | sodium arsenate | increases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of UBXN4 mRNA | CTD | PMID:21795629 | sodium arsenite | decreases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of UBXN4 protein | CTD | PMID:29044176 | testosterone enanthate | affects expression | ISO | UBXN4 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of UBXD2 mRNA | CTD | PMID:17440010 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBXN4 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of UBXN4 mRNA | CTD | PMID:31919559 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of UBXN4 mRNA | CTD | PMID:31150632 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of UBXN4 protein | CTD | PMID:35544339 | titanium dioxide | affects expression | ISO | Ubxn4 (Mus musculus) | 6480464 | titanium dioxide affects the expression of UBXN4 mRNA | CTD | PMID:17656681 | torcetrapib | increases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of UBXN4 mRNA | CTD | PMID:23228038 | trichostatin A | affects expression | ISO | UBXN4 (Homo sapiens) | 6480464 | trichostatin A affects the expression of UBXN4 mRNA | CTD | PMID:28542535 | Triptolide | decreases expression | EXP | | 6480464 | triptolide results in decreased expression of UBXN4 protein | CTD | PMID:32519852 | tungsten | decreases expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Tungsten results in decreased expression of UBXN4 mRNA | CTD | PMID:30912803 | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of UBXN4 mRNA | CTD | PMID:24136188 | valproic acid | affects expression | ISO | Ubxn4 (Mus musculus) | 6480464 | Valproic Acid affects the expression of UBXN4 mRNA | CTD | PMID:17292431 | valproic acid | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of UBXD2 mRNA | CTD | PMID:17183730 | valproic acid | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of UBXN4 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of UBXN4 mRNA | CTD | PMID:25979313 | vitamin E | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of UBXD2 mRNA | CTD | PMID:19244175 | vitamin E | multiple interactions | ISO | UBXN4 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of UBXD2 mRNA | CTD | PMID:19244175 | vorinostat | decreases expression | ISO | UBXN4 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of UBXN4 mRNA | CTD | PMID:27188386 | |