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| # | Reference Title | Reference Citation |
| 1. | Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy. | Brauch KM, etal., J Am Coll Cardiol. 2009 Sep 1;54(10):930-41. doi: 10.1016/j.jacc.2009.05.038. |
| 2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. | Guo W, etal., Nat Med. 2012 May;18(5):766-73. doi: 10.1038/nm.2693. |
| 4. | Pathophysiological defects and transcriptional profiling in the RBM20-/- rat model. | Guo W, etal., PLoS One. 2013 Dec 19;8(12):e84281. doi: 10.1371/journal.pone.0084281. eCollection 2013. |
| 5. | RBM20 and RBM24 cooperatively promote the expression of short enh splice variants. | Ito J, etal., FEBS Lett. 2016 Jul;590(14):2262-74. doi: 10.1002/1873-3468.12251. Epub 2016 Jul 4. |
| 6. | Rbm20 regulates titin alternative splicing as a splicing repressor. | Li S, etal., Nucleic Acids Res. 2013 Feb 1;41(4):2659-72. doi: 10.1093/nar/gks1362. Epub 2013 Jan 9. |
| 7. | RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing. | Maatz H, etal., J Clin Invest. 2014 Aug;124(8):3419-30. doi: 10.1172/JCI74523. Epub 2014 Jun 24. |
| 8. | RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures. | Maimaiti R, etal., Int J Mol Sci. 2021 Mar 13;22(6). pii: ijms22062928. doi: 10.3390/ijms22062928. |
| 9. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
| 10. | GOA pipeline | RGD automated data pipeline |
| 11. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 12. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 13. | RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis. | Zhang Y, etal., FASEB J. 2022 May;36(5):e22302. doi: 10.1096/fj.202101811RR. |
| 14. | RBM20 is an essential factor for thyroid hormone-regulated titin isoform transition. | Zhu C, etal., J Mol Cell Biol. 2015 Feb;7(1):88-90. doi: 10.1093/jmcb/mjv002. Epub 2015 Jan 8. |
| PMID:28676430 | PMID:29725258 | PMID:30133019 | PMID:31221019 | PMID:31717392 | PMID:35762193 |
| Rbm20 (Rattus norvegicus - Norway rat) |
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| RBM20 (Homo sapiens - human) |
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| Rbm20 (Mus musculus - house mouse) |
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| Rbm20 (Chinchilla lanigera - long-tailed chinchilla) |
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| RBM20 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| RBM20 (Canis lupus familiaris - dog) |
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| Rbm20 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| RBM20 (Sus scrofa - pig) |
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| RBM20 (Chlorocebus sabaeus - green monkey) |
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| Rbm20 (Heterocephalus glaber - naked mole-rat) |
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| Rbm20 (Rattus rattus - black rat) |
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| RH143918 |
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| RH141597 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 65 | 160 | 89 | 88 | 57 | 91 | 57 | 6 | 351 | 189 | 11 | 138 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001107611 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017589306 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039080732 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039080742 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039080744 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063265322 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063265325 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063265327 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063265334 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AC098942 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AC110709 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473986 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| EU562301 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000001 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000054685 ⟹ ENSRNOP00000051570 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000110758 ⟹ ENSRNOP00000096791 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000113904 ⟹ ENSRNOP00000091922 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001107611 ⟹ NP_001101081 | ||||||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017589306 ⟹ XP_017444795 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039080732 ⟹ XP_038936660 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039080742 ⟹ XP_038936670 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039080744 ⟹ XP_038936672 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063265322 ⟹ XP_063121392 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063265325 ⟹ XP_063121395 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063265327 ⟹ XP_063121397 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063265334 ⟹ XP_063121404 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001101081 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017444795 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038936660 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038936670 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038936672 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063121392 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063121395 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063121397 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063121404 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | ACD80091 | (Get FASTA) | NCBI Sequence Viewer |
| E9PT37 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL94439 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000051570 | ||
| ENSRNOP00000051570.2 |
| RefSeq Acc Id: | NP_001101081 ⟸ NM_001107611 |
| - UniProtKB: | C1IEE3 (UniProtKB/Swiss-Prot), E9PT37 (UniProtKB/Swiss-Prot) |
| - Sequence: |
| RefSeq Acc Id: | XP_017444795 ⟸ XM_017589306 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A8I6AGI3 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000051570 ⟸ ENSRNOT00000054685 |
| RefSeq Acc Id: | XP_038936660 ⟸ XM_039080732 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | E9PT37 (UniProtKB/Swiss-Prot), C1IEE3 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_038936670 ⟸ XM_039080742 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A8I6AGI3 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038936672 ⟸ XM_039080744 |
| - Peptide Label: | isoform X4 |
| Ensembl Acc Id: | ENSRNOP00000096791 ⟸ ENSRNOT00000110758 |
| Ensembl Acc Id: | ENSRNOP00000091922 ⟸ ENSRNOT00000113904 |
| RefSeq Acc Id: | XP_063121397 ⟸ XM_063265327 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A8I6AGI3 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063121392 ⟸ XM_063265322 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | E9PT37 (UniProtKB/Swiss-Prot), C1IEE3 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063121395 ⟸ XM_063265325 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A8I6AGI3 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063121404 ⟸ XM_063265334 |
| - Peptide Label: | isoform X4 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-E9PT37-F1-model_v2 | AlphaFold | E9PT37 | 1-1207 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1307427 | AgrOrtholog |
| BioCyc Gene | G2FUF-55380 | BioCyc |
| Ensembl Genes | ENSRNOG00000014705 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000054685 | ENTREZGENE |
| ENSRNOT00000054685.3 | UniProtKB/Swiss-Prot | |
| Gene3D-CATH | 3.30.70.330 | UniProtKB/Swiss-Prot |
| InterPro | Matrin/U1-C_Znf_C2H2 | UniProtKB/Swiss-Prot |
| Matrin/U1-like-C_Znf_C2H2 | UniProtKB/Swiss-Prot | |
| Nucleotide-bd_a/b_plait_sf | UniProtKB/Swiss-Prot | |
| RBD_domain_sf | UniProtKB/Swiss-Prot | |
| RBM20_RRM | UniProtKB/Swiss-Prot | |
| RRM_dom | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:309544 | UniProtKB/Swiss-Prot |
| NCBI Gene | 309544 | ENTREZGENE |
| PANTHER | MATRIN 3/NUCLEAR PROTEIN 220-RELATED | UniProtKB/Swiss-Prot |
| PhenoGen | Rbm20 | PhenoGen |
| PROSITE | RRM | UniProtKB/Swiss-Prot |
| ZF_MATRIN | UniProtKB/Swiss-Prot | |
| RatGTEx | ENSRNOG00000014705 | RatGTEx |
| SMART | RRM | UniProtKB/Swiss-Prot |
| ZnF_U1 | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF54928 | UniProtKB/Swiss-Prot |
| UniProt | A0A8I6AGI3 | ENTREZGENE, UniProtKB/TrEMBL |
| C1IEE3 | ENTREZGENE | |
| E9PT37 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| UniProt Secondary | C1IEE3 | UniProtKB/Swiss-Prot |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2008-04-30 | Rbm20 | RNA binding motif protein 20 | Rbm20_predicted | RNA binding motif protein 20 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Rbm20_predicted | RNA binding motif protein 20 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |