Mrps21l (mitochondrial ribosomal protein S21-like) - Rat Genome Database

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Pathways
Gene: Mrps21l (mitochondrial ribosomal protein S21-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mrps21l
Name: mitochondrial ribosomal protein S21-like
RGD ID: 1307398
Description: INTERACTS WITH fipronil
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: MODEL
Previously known as: 28S ribosomal protein S21, mitochondrial; 28S ribosomal protein S21, mitochondrial-like; LOC100911433; LOC364906; mitochondrial ribosomal protein S21; Mrps21; small ribosomal subunit protein bS21m
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81875,687,080 - 75,687,554 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21873,412,080 - 73,412,549 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1873,412,141 - 73,412,443 (+)EnsemblmRatBN7.2
Rnor_6.01876,317,077 - 76,317,542 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1872,649,613 - 72,649,915 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl1876,317,134 - 76,317,436 (+)Ensemblrn6Rnor6.0
Rnor_5.01875,991,967 - 75,992,436 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41876,893,022 - 76,893,324 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1871,918,225 - 71,918,694 (+)NCBICelera
RGSC_v3.11876,966,294 - 76,966,597 (+)NCBI
Cytogenetic Map18q12.3NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
fipronil  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:196
Count of miRNA genes:67
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000072205, ENSRNOT00000074465
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186289225779484461Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)186438376279484311Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
7794793Mcs34Mammary carcinoma susceptibility QTL 341.54mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)186563556785897775Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)186584644786134022Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186198220476619168Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186289225779484461Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)186144685386134022Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185449080176272247Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat

Markers in Region
AI008709  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01872,334,056 - 72,334,284NCBIRnor5.0
Rnor_5.0345,614,428 - 45,614,617NCBIRnor5.0
Rnor_5.01875,992,053 - 75,992,281NCBIRnor5.0
RGSC_v3.4336,560,849 - 36,561,037UniSTSRGSC3.4
RGSC_v3.41876,893,048 - 76,893,275UniSTSRGSC3.4
Celera337,575,429 - 37,575,617UniSTS
Celera1871,918,312 - 71,918,539UniSTS
RH 3.4 Map18812.7UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map3q12UniSTS
Cytogenetic Map18q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
4 9 8 5 2 8 2 23 11 14 6 11 3 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_344706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000072205   ⟹   ENSRNOP00000064559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1872,649,613 - 72,649,915 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000074465   ⟹   ENSRNOP00000063992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1876,317,134 - 76,317,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1873,412,141 - 73,412,443 (+)Ensembl
RefSeq Acc Id: XM_344706   ⟹   XP_344707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,687,080 - 75,687,554 (+)NCBI
mRatBN7.21873,412,080 - 73,412,549 (+)NCBI
Rnor_6.01876,317,077 - 76,317,542 (+)NCBI
Rnor_5.01875,991,967 - 75,992,436 (+)NCBI
RGSC_v3.41876,893,022 - 76,893,324 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_344707 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_344707   ⟸   XM_344706
- Sequence:
Ensembl Acc Id: ENSRNOP00000063992   ⟸   ENSRNOT00000074465
Ensembl Acc Id: ENSRNOP00000064559   ⟸   ENSRNOT00000072205

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R3S1-F1-model_v2 AlphaFold M0R3S1 1-88 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700898
Promoter ID:EPDNEW_R11409
Type:multiple initiation site
Name:Mrps21l_1
Description:mitochondrial ribosomal protein S21-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01876,317,068 - 76,317,128EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307398 AgrOrtholog
BioCyc Gene G2FUF-6875 BioCyc
Ensembl Genes ENSRNOG00000048409 Ensembl
  ENSRNOG00000049921 Ensembl
  ENSRNOG00000066960 Ensembl
NCBI Gene 364906 ENTREZGENE
PhenoGen Mrps21l PhenoGen
RatGTEx ENSRNOG00000048409 RatGTEx
  ENSRNOG00000049921 RatGTEx
  ENSRNOG00000066960 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mrps21l  mitochondrial ribosomal protein S21-like  LOC100911433  28S ribosomal protein S21, mitochondrial-like  Data merged from RGD:6493026 737654 PROVISIONAL
2012-07-05 LOC100911433  28S ribosomal protein S21, mitochondrial-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-05-02 Mrps21l  mitochondrial ribosomal protein S21-like  Mrps21_predicted  mitochondrial ribosomal protein S21 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Mrps21_predicted  mitochondrial ribosomal protein S21 (predicted)      Symbol and Name status set to approved 70820 APPROVED