Gem (GTP binding protein overexpressed in skeletal muscle) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gem (GTP binding protein overexpressed in skeletal muscle) Rattus norvegicus
Analyze
Symbol: Gem
Name: GTP binding protein overexpressed in skeletal muscle
RGD ID: 1307386
Description: Predicted to enable several functions, including calcium channel regulator activity; guanyl ribonucleotide binding activity; and magnesium ion binding activity. Predicted to be involved in chromosome organization; metaphase chromosome alignment; and mitotic cell cycle. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; midbody; and spindle. Predicted to be active in plasma membrane. Biomarker of glaucoma. Orthologous to human GEM (GTP binding protein overexpressed in skeletal muscle); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GTP binding protein (gene overexpressed in skeletal muscle); GTP-binding protein GEM; LOC297902
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8530,011,641 - 30,022,554 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl530,011,592 - 30,022,542 (+)EnsemblGRCr8
mRatBN7.2525,214,309 - 25,225,222 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl525,214,309 - 25,225,222 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx527,339,200 - 27,350,185 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0528,931,944 - 28,942,929 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0528,874,165 - 28,885,140 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd530,141,607 - 30,152,582 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive531,571,855 - 31,582,768 (+)NCBILyon_Normotensive
Lyon_Hypertensive530,998,362 - 31,009,275 (+)NCBILyon_Hypertensive
F344_StmMcwi524,779,413 - 24,790,388 (+)NCBIF344_StmMcwi
Rnor_6.0525,339,479 - 25,353,661 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl525,349,928 - 25,353,661 (+)Ensemblrn6Rnor6.0
Rnor_5.0530,050,664 - 30,062,666 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4525,809,543 - 26,008,249 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera524,546,414 - 24,557,484 (+)NCBICelera
RGSC_v3.1526,004,470 - 26,008,270 (+)NCBI
Cytogenetic Map5q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
glaucoma  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
acetaldehyde  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
albendazole  (ISO)
aldehydo-D-glucose  (ISO)
amiodarone  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
CU-O LINKAGE  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
endosulfan  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glucose  (ISO)
Heliotrine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
irinotecan  (EXP)
iron dichloride  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
methamphetamine  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Integrated microarray analysis provided novel insights to the pathogenesis of glaucoma. Wang J, etal., Mol Med Rep. 2017 Dec;16(6):8735-8746. doi: 10.3892/mmr.2017.7711. Epub 2017 Oct 4.
Additional References at PubMed
PMID:7912851   PMID:12477932   PMID:15860732   PMID:17052716   PMID:17107948   PMID:18480465   PMID:22964304   PMID:23076376   PMID:23602967   PMID:24948002  


Genomics

Comparative Map Data
Gem
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8530,011,641 - 30,022,554 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl530,011,592 - 30,022,542 (+)EnsemblGRCr8
mRatBN7.2525,214,309 - 25,225,222 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl525,214,309 - 25,225,222 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx527,339,200 - 27,350,185 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0528,931,944 - 28,942,929 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0528,874,165 - 28,885,140 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd530,141,607 - 30,152,582 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive531,571,855 - 31,582,768 (+)NCBILyon_Normotensive
Lyon_Hypertensive530,998,362 - 31,009,275 (+)NCBILyon_Hypertensive
F344_StmMcwi524,779,413 - 24,790,388 (+)NCBIF344_StmMcwi
Rnor_6.0525,339,479 - 25,353,661 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl525,349,928 - 25,353,661 (+)Ensemblrn6Rnor6.0
Rnor_5.0530,050,664 - 30,062,666 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4525,809,543 - 26,008,249 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera524,546,414 - 24,557,484 (+)NCBICelera
RGSC_v3.1526,004,470 - 26,008,270 (+)NCBI
Cytogenetic Map5q13NCBI
GEM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38894,249,253 - 94,262,319 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl894,249,249 - 94,262,461 (-)Ensemblhg38GRCh38
GRCh37895,261,481 - 95,274,547 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36895,330,657 - 95,343,733 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34895,330,662 - 95,343,733NCBI
Celera891,447,594 - 91,460,660 (-)NCBICelera
Cytogenetic Map8q22.1NCBI
HuRef890,470,565 - 90,483,631 (-)NCBIHuRef
CHM1_1895,301,787 - 95,314,853 (-)NCBICHM1_1
T2T-CHM13v2.0895,374,122 - 95,387,192 (-)NCBIT2T-CHM13v2.0
Gem
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39411,702,379 - 11,714,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl411,704,457 - 11,714,752 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38411,704,447 - 11,714,993 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl411,704,457 - 11,714,752 (+)Ensemblmm10GRCm38
MGSCv37411,631,594 - 11,642,140 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36411,631,604 - 11,641,899 (+)NCBIMGSCv36mm8
Celera411,515,538 - 11,526,084 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map45.34NCBI
Gem
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541710,475,822 - 10,487,825 (-)Ensembl
ChiLan1.0NW_00495541710,475,967 - 10,486,879 (-)NCBIChiLan1.0ChiLan1.0
GEM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27111,582,105 - 111,595,278 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1887,119,098 - 87,132,234 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0890,872,855 - 90,885,969 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1892,817,028 - 92,830,133 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl892,817,028 - 92,830,133 (-)EnsemblpanPan2panpan1.1
GEM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12939,016,543 - 39,037,761 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2939,025,483 - 39,037,403 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2939,177,842 - 39,199,013 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02939,220,477 - 39,241,164 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2939,229,312 - 39,239,841 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12939,234,088 - 39,255,249 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02939,229,276 - 39,250,433 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02939,670,894 - 39,692,020 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gem
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530340,516,800 - 40,530,076 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365447,262,629 - 7,275,910 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365447,262,629 - 7,275,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GEM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl442,458,466 - 42,471,929 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1442,458,591 - 42,471,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2445,876,630 - 45,889,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GEM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1889,219,484 - 89,232,788 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl889,218,782 - 89,232,753 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603951,615,735 - 51,629,058 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gem
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247631,654,130 - 1,666,540 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247631,654,369 - 1,666,538 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gem
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11131,851,263 - 131,862,438 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gem
92 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:85
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000020826
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
RH140150  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4525,857,958 - 25,858,142UniSTSRGSC3.4
Celera524,403,129 - 24,403,313UniSTS
RH 3.4 Map5138.5UniSTS
Cytogenetic Map5q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 164 91 90 59 91 59 6 354 190 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020826   ⟹   ENSRNOP00000020826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl530,011,592 - 30,022,542 (+)Ensembl
mRatBN7.2 Ensembl525,214,309 - 25,225,222 (+)Ensembl
Rnor_6.0 Ensembl525,349,928 - 25,353,661 (+)Ensembl
RefSeq Acc Id: NM_001106637   ⟹   NP_001100107
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8530,011,641 - 30,022,554 (+)NCBI
mRatBN7.2525,214,309 - 25,225,222 (+)NCBI
Dahl_SR_JrHsd530,141,607 - 30,152,582 (+)NCBI
Lyon_Normotensive531,571,855 - 31,582,768 (+)NCBI
Lyon_Hypertensive530,998,362 - 31,009,275 (+)NCBI
F344_StmMcwi524,779,413 - 24,790,388 (+)NCBI
Rnor_6.0525,339,479 - 25,353,661 (+)NCBI
Rnor_5.0530,050,664 - 30,062,666 (+)NCBI
RGSC_v3.4525,809,543 - 26,008,249 (+)RGD
Celera524,546,414 - 24,557,484 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100107 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68988 (Get FASTA)   NCBI Sequence Viewer  
  EDL98442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020826
  ENSRNOP00000020826.6
RefSeq Acc Id: NP_001100107   ⟸   NM_001106637
- UniProtKB: B5DFA6 (UniProtKB/TrEMBL),   E9PT99 (UniProtKB/TrEMBL),   A0A9K3Y811 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020826   ⟸   ENSRNOT00000020826

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PT99-F1-model_v2 AlphaFold E9PT99 1-188 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307386 AgrOrtholog
BioCyc Gene G2FUF-41918 BioCyc
Ensembl Genes ENSRNOG00000015160 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020826 ENTREZGENE
  ENSRNOT00000020826.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  RGK_GTP-binding_reg UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase_GEM/REM/Rad UniProtKB/TrEMBL
KEGG Report rno:297902 UniProtKB/TrEMBL
NCBI Gene 297902 ENTREZGENE
PANTHER GTP-BINDING PROTEIN GEM UniProtKB/TrEMBL
  RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PhenoGen Gem PhenoGen
PIRSF GTP-binding_GEM UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015160 RatGTEx
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A9K3Y811 ENTREZGENE, UniProtKB/TrEMBL
  B5DFA6 ENTREZGENE, UniProtKB/TrEMBL
  E9PT99 ENTREZGENE
UniProt Secondary E9PT99 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-16 Gem  GTP binding protein overexpressed in skeletal muscle  Gem  GTP binding protein (gene overexpressed in skeletal muscle)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Gem  GTP binding protein (gene overexpressed in skeletal muscle)   Gem_predicted  GTP binding protein (gene overexpressed in skeletal muscle) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gem_predicted  GTP binding protein (gene overexpressed in skeletal muscle) (predicted)      Symbol and Name status set to approved 70820 APPROVED