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Gene: Jmjd8 (jumonji domain containing 8) Rattus norvegicus

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Symbol:

Jmjd8

Name:

jumonji domain containing 8

RGD ID:

1307381

Description:

Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; positive regulation of sprouting angiogenesis; and regulation of pyruvate kinase activity. Predicted to act upstream of or within cellular respiration and sprouting angiogenesis. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in nucleus. Orthologous to human JMJD8 (jumonji domain containing 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

jmjC domain-containing protein 8; jumonji domain-containing protein 8; LOC360498; RGD1307381; similar to RIKEN cDNA 2610003J06

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	JMJD8 (jumonji domain containing 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Jmjd8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Jmjd8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	JMJD8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	JMJD8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Jmjd8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	JMJD8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	JMJD8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Jmjd8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Jmjd8 (jumonji domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Jmjd8 (jumonji domain containing 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	JMJD8 (jumonji domain containing 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	jmjd8 (jumonji domain containing 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C27F2.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	jmjd8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	15,353,460 - 15,356,392 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	15,353,475 - 15,356,393 (+)	Ensembl				GRCr8
mRatBN7.2	10	14,848,965 - 14,851,881 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	14,848,980 - 14,851,879 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	19,587,989 - 19,590,888 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	19,076,865 - 19,079,764 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	14,577,145 - 14,580,044 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	15,195,954 - 15,198,870 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	15,195,969 - 15,198,868 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	15,008,882 - 15,011,813 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	15,094,365 - 15,097,264 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	14,517,922 - 14,520,821 (+)	NCBI		Celera
RGSC_v3.1	10	15,094,364 - 15,097,264 (+)	NCBI
Cytogenetic Map	10	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

chlordecone (ISO)

clobetasol (ISO)

clofibrate (ISO)

dexamethasone (ISO)

ethanol (ISO)

fenthion (ISO)

indometacin (ISO)

inulin (ISO)

isobutanol (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methidathion (ISO)

nickel sulfate (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

potassium chromate (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloroethene (ISO)

thioacetamide (EXP)

thiram (ISO)

trichloroethene (EXP)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular respiration (ISO)

positive regulation of canonical NF-kappaB signal transduction (IEA,ISO,ISS)

positive regulation of sprouting angiogenesis (IEA,ISO,ISS)

regulation of glycolytic process (IEA,ISO,ISS)

regulation of pyruvate kinase activity (ISO,ISS)

sprouting angiogenesis (ISO)

Cellular Component

cytoplasm (IEA,ISO,ISS)

endoplasmic reticulum (IEA,ISO,ISS)

endoplasmic reticulum lumen (IEA,ISO,ISS)

nucleus (IBA,IEA,ISO,ISS)

Molecular Function

cis-regulatory region sequence-specific DNA binding (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:23376485	PMID:27199445	PMID:27671354	PMID:29133832

Genomics

Comparative Map Data

Jmjd8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	15,353,460 - 15,356,392 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	15,353,475 - 15,356,393 (+)	Ensembl				GRCr8
mRatBN7.2	10	14,848,965 - 14,851,881 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	14,848,980 - 14,851,879 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	19,587,989 - 19,590,888 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	19,076,865 - 19,079,764 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	14,577,145 - 14,580,044 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	15,195,954 - 15,198,870 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	15,195,969 - 15,198,868 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	15,008,882 - 15,011,813 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	15,094,365 - 15,097,264 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	14,517,922 - 14,520,821 (+)	NCBI		Celera
RGSC_v3.1	10	15,094,364 - 15,097,264 (+)	NCBI
Cytogenetic Map	10	q12	NCBI

JMJD8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	681,670 - 684,334 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	681,666 - 684,528 (-)	Ensembl			hg38	GRCh38
GRCh37	16	731,670 - 734,334 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	671,668 - 674,440 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	16	931,824 - 934,596 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	653,544 - 656,316 (-)	NCBI		HuRef
CHM1_1	16	731,641 - 734,413 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	685,745 - 688,409 (-)	NCBI		T2T-CHM13v2.0

Jmjd8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	26,048,017 - 26,050,817 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	26,047,841 - 26,050,817 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	25,829,043 - 25,831,843 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	25,828,867 - 25,831,843 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	25,965,988 - 25,968,788 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	25,556,647 - 25,559,366 (+)	NCBI		MGSCv36	mm8
Celera	17	26,361,866 - 26,364,666 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.92	NCBI

Jmjd8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	16,519,397 - 16,521,106 (+)	Ensembl
ChiLan1.0	NW_004955442	16,519,394 - 16,521,106 (+)	NCBI	ChiLan1.0	ChiLan1.0

JMJD8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	922,875 - 925,741 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	4,706,742 - 4,709,753 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	16	695,575 - 698,914 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	696,710 - 698,767 (-)	Ensembl			panPan2	panpan1.1

JMJD8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	39,891,930 - 39,894,549 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	39,891,926 - 39,927,919 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	41,155,908 - 41,158,679 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	40,234,435 - 40,237,206 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	40,234,598 - 40,236,100 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	39,923,171 - 39,925,768 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	39,883,208 - 39,885,977 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	40,362,346 - 40,365,117 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Jmjd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	112,229,160 - 112,231,959 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	327,150 - 328,720 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	327,053 - 328,789 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JMJD8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	41,090,788 - 41,093,614 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	41,090,787 - 41,093,620 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	41,384,093 - 41,386,829 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JMJD8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	601,462 - 604,342 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	602,597 - 604,182 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666068	30,532,849 - 30,535,696 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Jmjd8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	1,494,168 - 1,495,801 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624913	1,494,168 - 1,495,864 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Jmjd8
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	3,094,368 - 3,097,284 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Jmjd8
3 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	208
Count of miRNA genes:	144
Interacting mature miRNAs:	175
Transcripts:	ENSRNOT00000026789
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
631828	Alc5	Alcohol consumption QTL 5	2.4		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	1	17749933	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat

Markers in Region

19.MMHAP26FLG1.seq

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,849,456 - 14,849,638 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	15,196,446 - 15,196,627	NCBI	Rnor6.0
Rnor_5.0	10	15,009,389 - 15,009,570	UniSTS	Rnor5.0
RGSC_v3.4	10	15,094,842 - 15,095,023	UniSTS	RGSC3.4
Celera	10	14,518,399 - 14,518,580	UniSTS
Cytogenetic Map	10	q12	UniSTS

AA957388

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,850,836 - 14,851,034 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	15,197,826 - 15,198,023	NCBI	Rnor6.0
Rnor_5.0	10	15,010,769 - 15,010,966	UniSTS	Rnor5.0
RGSC_v3.4	10	15,096,222 - 15,096,419	UniSTS	RGSC3.4
Celera	10	14,519,779 - 14,519,976	UniSTS
RH 3.4 Map	10	154.2	UniSTS
Cytogenetic Map	10	q12	UniSTS

RH134746

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,848,589 - 14,848,776 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	15,195,579 - 15,195,765	NCBI	Rnor6.0
Rnor_5.0	10	15,008,522 - 15,008,708	UniSTS	Rnor5.0
RGSC_v3.4	10	15,093,975 - 15,094,161	UniSTS	RGSC3.4
Celera	10	14,517,532 - 14,517,718	UniSTS
RH 3.4 Map	10	156.6	UniSTS
Cytogenetic Map	10	q12	UniSTS

RH137204

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,851,593 - 14,851,812 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	15,198,583 - 15,198,801	NCBI	Rnor6.0
Rnor_5.0	10	15,011,526 - 15,011,744	UniSTS	Rnor5.0
RGSC_v3.4	10	15,096,979 - 15,097,197	UniSTS	RGSC3.4
Celera	10	14,520,536 - 14,520,754	UniSTS
RH 3.4 Map	10	154.5	UniSTS
Cytogenetic Map	10	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026789 ⟹ ENSRNOP00000026789

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	15,353,475 - 15,356,393 (+)	Ensembl
mRatBN7.2 Ensembl	10	14,848,980 - 14,851,879 (+)	Ensembl
Rnor_6.0 Ensembl	10	15,195,969 - 15,198,868 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082567 ⟹ ENSRNOP00000069837

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	15,196,130 - 15,197,706 (+)	Ensembl

RefSeq Acc Id:

NM_001014116 ⟹ NP_001014138

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,353,493 - 15,356,392 (+)	NCBI
mRatBN7.2	10	14,848,980 - 14,851,879 (+)	NCBI
Rnor_6.0	10	15,195,969 - 15,198,868 (+)	NCBI
Rnor_5.0	10	15,008,882 - 15,011,813 (+)	NCBI
RGSC_v3.4	10	15,094,365 - 15,097,264 (+)	RGD
Celera	10	14,517,922 - 14,520,821 (+)	RGD

Sequence:

show sequence

CAATGGCTGCTCAATACAGTTTCACTCCGCCTTGAGGAAATGATTAAATAGGGGTTTTGTGTGG
ATGTGGATGTTTGTACTCGCGCGTGTACGAGGAGGAGGCTCCCAGGGCCGGCTGGCTACTGCTT
GCAGGTAGCTACAGCAGTCCAGACCCTAAGCCAATGGCTTGTGCTTTCGTAAGTGTCGACAGAA
TTCCCAGCGTGCTGCGCGCCTGCACCCGTATGCTCATGGCGGCGGCTGGACGATTCGGTCTGCT
TTTGCTCATTGTACTATGGACGATGGTGACTGTGGTTCTGCCTGCCTCTGGCGAAGGGGGATGG
AAACAGAGTAGGCTGGGAACTGAAGCAGCGGTGATGGAGGAGGAACGTTGCACAGTCGAGCGCC
GAGCACACCTCACGTACTCCGAATTTATGCAGCACTATGCCTTCCTCAAGCCCGTCATCTTGCA
AGGACTCACAGACAACTCGAAGTTCAGAGCCCTGTGTTCCCGGGAAAACCTGCTGGCCTCGTTT
GGGGACAATGTTGTTCGCTTGAGTACAGCCAACACCTACTCCTACCAGAAAGTGGACCTGCCTT
TCCAGGAATATGTGGAGCAGCTGCTGCACCCCCAGGACCCCGAATCTCTAGGCAATGACACCCT
GTACTTTTTCGGAGATAACAACTTTACTGAGTGGGCCCCACTCTTCCAACATTACCGTCCACCT
CCATTTCGTCTACTGGGAACCACCCCTGCTTATAGCTTTGGAATTGCAGGAGCTGGATCTGGGG
TACCCTTCCACTGGCATGGGCCTGGTTTCTCAGAGGTTATCTATGGTCGGAAGCGCTGGTTCCT
CTACCCTCCTGAGAAGACACCTGAGTTCCACCCTAACAAGACCACGTTGGCCTGGCTCCTGGAA
ATATACCCATCTCTAGCCCCATCAGCTCGGCCTCTAGAATGTACCATCCAGGCTGGTGAAGCGC
TGTACTTTCCTGATCGGTGGTGGCATGCCACACTCAATCTGGACACCAGTGTCTTCATATCCAC
TTTCCTTGGCTAGCCAACAAGCGACTGGCAAGCCCACTGCACCAGCACATGCCAATGTAGTGCT
CACAGACTTTATTACAGGACAGTGGCAGCAGCAGCAGCAACCCACCCTCACCAGCTCTCCAGCC
CAGAAGGGAGACAAGGGAGGCTCATGGCCCAGCAAGGGATATGCTGAGAAGGGGAGCAGTTCAG
AACCCATCATCAGGACCGATGGGGGCAGGCCCAGGGACACAAACTATATACAGGGACTGGAGCT
TCTGCCTCCAGACCCTCCTGGGCCAGGGTGCCAGGCAGGACATGGGGTATCAGTAGTCCTCTAC
CCAGCCATTCTCAGAGATGAAAGCATCAATGACTTCCTTCATGGCTAAGTTGGGGATGAGCTGT
TCCTGGGTCAGAGGGCTCCGGGTCACAGGATCGAAATGGCCCACGCGCTGCAACGACAGAGTCA
AGAGTATTCAATGGCCTGAGTGTCCCCTGATCCCAGTCCCGAGACCACAGGCCCTCCTTACCTG
CAGGTGCTCCTCAATGTCCTTGCGGTCATAGGTGATGCCACTGGGTGTAATGCAGGGTTCCCGC
ATCAGCTCAAAGCTGATCTTGCCACACAAGTAGTCAGGGATATCTCGCTTCTGCAGCACAAGAG
GGAAATGTCTGCAACTGGAAAGGAAGTCACCATACCAGAGCCTGCCCATGAGCTTCAAGGCTCC
GTCCTTACCTTTCTTTTCTCATCCACCTGAGAGAAGAGCTCATTCATGTCCGCCATGTATTTAT
CCTGCAGAGTTGAGCGCCATGTGTGGGCAACTCCTGTCTCCTCCACACAGACACACACACTCTG
TCCACCGGGGCACTCATGTCATGCATGGGCCAACAGAGCCACCATAGGCTGGGGCACTTCTCAT
GCCACACACAAAAACACACACACAACGACCCACATGTGGACTAGGGGCACCCTCACGTGCTTGG
CCTCAATGCAGGCCTGCTGGGCCCTGATGTGGCCATCATCCTCATCACCCTCGTGGTTCCGCTG
ACACTCTTCCAGTTCCCTGAGGGTCAAGAAAAAGCCAGCTGGTGATGGCCCCAACAGGGAAATG
ACAGATCCCTTCCCATCTCAGGCCTCTTTCCTCCCGGGCTTCCCATGTACCGGCTGCTGTCCTT
TAATAAACACTTGCACTGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006245999 ⟹ XP_006246061

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	15,353,460 - 15,356,392 (+)	NCBI
mRatBN7.2	10	14,848,974 - 14,851,881 (+)	NCBI
Rnor_6.0	10	15,195,956 - 15,198,870 (+)	NCBI
Rnor_5.0	10	15,008,882 - 15,011,813 (+)	NCBI

Sequence:

show sequence

AACCCGCTGTAGTCAATGGCTGCTCAATACAGTTTCACTCCGCCTTGAGGAAATGATTAAATAG
GGGTTTTGTGTGGATGTGGATGTTTGTACTCGCGCGTGTACGAGGAGGAGGCTCCCAGGGCCGG
CTGGCTACTGCTTGCAGGTAGCTACAGCAGTCCAGACCCTAAGCCAATGGCTTGTGCTTTCGTA
AGTGTCGACAGAATTCCCAGCGTGCTGCGCGCCTGCACCCGTATGCTCATGGCGGCGGCTGGAC
GATTCGGTCTGCTTTTGCTCATTGTACTATGGACGATGGTGACTGTGGTTCTGCCTGCCTCTGG
CGAAGGGGGATGGAAACAGAGTAGGCTGGGAACTGAAGCAGCGGTGATGGAGGAGGAACGTTGC
ACAGTCGAGCGCCGAGCACACCTCACGTACTCCGAATTTATGCAGCACTATGCCTTCCTCAAGC
CCGTCATCTTGCAAGGACTCACAGACAACTCGTTCAGAGCCCTGTGTTCCCGGGAAAACCTGCT
GGCCTCGTTTGGGGACAATGTTGTTCGCTTGAGTACAGCCAACACCTACTCCTACCAGAAAGTG
GACCTGCCTTTCCAGGAATATGTGGAGCAGCTGCTGCACCCCCAGGACCCCGAATCTCTAGGCA
ATGACACCCTGTACTTTTTCGGAGATAACAACTTTACTGAGTGGGCCCCACTCTTCCAACATTA
CCGTCCACCTCCATTTCGTCTACTGGGAACCACCCCTGCTTATAGCTTTGGAATTGCAGGAGCT
GGATCTGGGGTACCCTTCCACTGGCATGGGCCTGGTTTCTCAGAGGTTATCTATGGTCGGAAGC
GCTGGTTCCTCTACCCTCCTGAGAAGACACCTGAGTTCCACCCTAACAAGACCACGTTGGCCTG
GCTCCTGGAAATATACCCATCTCTAGCCCCATCAGCTCGGCCTCTAGAATGTACCATCCAGGCT
GGTGAAGCGCTGTACTTTCCTGATCGGTGGTGGCATGCCACACTCAATCTGGACACCAGTGTCT
TCATATCCACTTTCCTTGGCTAGCCAACAAGCGACTGGCAAGCCCACTGCACCAGCACATGCCA
ATGTAGTGCTCACAGACTTTATTACAGGACAGTGGCAGCAGCAGCAGCAACCCACCCTCACCAG
CTCTCCAGCCCAGAAGGGAGACAAGGGAGGCTCATGGCCCAGCAAGGGATATGCTGAGAAGGGG
AGCAGTTCAGAACCCATCATCAGGACCGATGGGGGCAGGCCCAGGGACACAAACTATATACAGG
GACTGGAGCTTCTGCCTCCAGACCCTCCTGGGCCAGGGTGCCAGGCAGGACATGGGGTATCAGT
AGTCCTCTACCCAGCCATTCTCAGAGATGAAAGCATCAATGACTTCCTTCATGGCTAAGTTGGG
GATGAGCTGTTCCTGGGTCAGAGGGCTCCGGGTCACAGGATCGAAATGGCCCACGCGCTGCAAC
GACAGAGTCAAGAGTATTCAATGGCCTGAGTGTCCCCTGATCCCAGTCCCGAGACCACAGGCCC
TCCTTACCTGCAGGTGCTCCTCAATGTCCTTGCGGTCATAGGTGATGCCACTGGGTGTAATGCA
GGGTTCCCGCATCAGCTCAAAGCTGATCTTGCCACACAAGTAGTCAGGGATATCTCGCTTCTGC
AGCACAAGAGGGAAATGTCTGCAACTGGAAAGGAAGTCACCATACCAGAGCCTGCCCATGAGCT
TCAAGGCTCCGTCCTTACCTTTCTTTTCTCATCCACCTGAGAGAAGAGCTCATTCATGTCCGCC
ATGTATTTATCCTGCAGAGTTGAGCGCCATGTGTGGGCAACTCCTGTCTCCTCCACACAGACAC
ACACACTCTGTCCACCGGGGCACTCATGTCATGCATGGGCCAACAGAGCCACCATAGGCTGGGG
CACTTCTCATGCCACACACAAAAACACACACACAACGACCCACATGTGGACTAGGGGCACCCTC
ACGTGCTTGGCCTCAATGCAGGCCTGCTGGGCCCTGATGTGGCCATCATCCTCATCACCCTCGT
GGTTCCGCTGACACTCTTCCAGTTCCCTGAGGGTCAAGAAAAAGCCAGCTGGTGATGGCCCCAA
CAGGGAAATGACAGATCCCTTCCCATCTCAGGCCTCTTTCCTCCCGGGCTTCCCATGTACCGGC
TGCTGTCCTTTAATAAACACTTGCACTGTTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001014138	(Get FASTA)	NCBI Sequence Viewer
	XP_006246061	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79205	(Get FASTA)	NCBI Sequence Viewer
	EDM03964	(Get FASTA)	NCBI Sequence Viewer
	EDM03965	(Get FASTA)	NCBI Sequence Viewer
	EDM03966	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026789
GenBank Protein	Q6AY40	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001014138 ⟸ NM_001014116
- Peptide Label:	precursor
- UniProtKB:	Q6AY40 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MLMAAAGRFGLLLLIVLWTMVTVVLPASGEGGWKQSRLGTEAAVMEEERCTVERRAHLTYSEFM QHYAFLKPVILQGLTDNSKFRALCSRENLLASFGDNVVRLSTANTYSYQKVDLPFQEYVEQLLH PQDPESLGNDTLYFFGDNNFTEWAPLFQHYRPPPFRLLGTTPAYSFGIAGAGSGVPFHWHGPGF SEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLLEIYPSLAPSARPLECTIQAGEALYFPDRWWHA TLNLDTSVFISTFLG hide sequence

RefSeq Acc Id:	XP_006246061 ⟸ XM_006245999
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QF73 (UniProtKB/TrEMBL), A6HD59 (UniProtKB/TrEMBL)
- Sequence:	show sequence MACAFVSVDRIPSVLRACTRMLMAAAGRFGLLLLIVLWTMVTVVLPASGEGGWKQSRLGTEAAV MEEERCTVERRAHLTYSEFMQHYAFLKPVILQGLTDNSFRALCSRENLLASFGDNVVRLSTANT YSYQKVDLPFQEYVEQLLHPQDPESLGNDTLYFFGDNNFTEWAPLFQHYRPPPFRLLGTTPAYS FGIAGAGSGVPFHWHGPGFSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLLEIYPSLAPSARPL ECTIQAGEALYFPDRWWHATLNLDTSVFISTFLG hide sequence

Ensembl Acc Id:

ENSRNOP00000069837 ⟸ ENSRNOT00000082567

Ensembl Acc Id:

ENSRNOP00000026789 ⟸ ENSRNOT00000026789

Protein Domains

JmjC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY40-F1-model_v2	AlphaFold	Q6AY40	1-271	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697059

Promoter ID:

EPDNEW_R7584

Type:

multiple initiation site

Name:

Jmjd8_2

Description:

jumonji domain containing 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7585

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	15,195,947 - 15,196,007	EPDNEW

RGD ID:

13697067

Promoter ID:

EPDNEW_R7585

Type:

multiple initiation site

Name:

Jmjd8_1

Description:

jumonji domain containing 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7584

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	15,196,190 - 15,196,250	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307381	AgrOrtholog
BioCyc Gene	G2FUF-25752	BioCyc
Ensembl Genes	ENSRNOG00000019729	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000026789	ENTREZGENE
Gene3D-CATH	Cupin	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7131778	IMAGE-MGC_LOAD
InterPro	Cupin_8	UniProtKB/Swiss-Prot
	JmjC_dom	UniProtKB/Swiss-Prot
	JMJD6_ArgDemeth/LysHydrox	UniProtKB/Swiss-Prot
KEGG Report	rno:360498	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94267	IMAGE-MGC_LOAD
NCBI Gene	360498	ENTREZGENE
PANTHER	ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD	UniProtKB/Swiss-Prot
	JMJC DOMAIN-CONTAINING PROTEIN 8	UniProtKB/Swiss-Prot
Pfam	Cupin_8	UniProtKB/Swiss-Prot
PhenoGen	Jmjd8	PhenoGen
PROSITE	JMJC	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000019729	RatGTEx
Superfamily-SCOP	Clavaminate synthase-like	UniProtKB/Swiss-Prot
UniProt	A0A8L2QF73	ENTREZGENE, UniProtKB/TrEMBL
	A6HD59	ENTREZGENE, UniProtKB/TrEMBL
	JMJD8_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-09	Jmjd8	jumonji domain containing 8	RGD1307381	similar to RIKEN cDNA 2610003J06	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1307381	similar to RIKEN cDNA 2610003J06	RGD1307381_predicted	similar to RIKEN cDNA 2610003J06 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1307381_predicted	similar to RIKEN cDNA 2610003J06 (predicted)	LOC360498_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC360498_predicted	similar to RIKEN cDNA 2610003J06 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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