Arhgap22 (Rho GTPase activating protein 22) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Arhgap22 (Rho GTPase activating protein 22) Rattus norvegicus
Analyze
Symbol: Arhgap22
Name: Rho GTPase activating protein 22
RGD ID: 1307237
Description: Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of small GTPase mediated signal transduction and regulation of postsynapse organization. Predicted to be active in glutamatergic synapse. Orthologous to human ARHGAP22 (Rho GTPase activating protein 22); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC306279; rho GTPase-activating protein 22
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,480,222 - 8,637,823 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl168,479,956 - 8,637,822 (+)EnsemblGRCr8
mRatBN7.2168,473,806 - 8,631,552 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,476,306 - 8,631,548 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx168,600,860 - 8,650,867 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0169,745,577 - 9,795,573 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0168,595,355 - 8,645,379 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,454,269 - 9,613,508 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,486,832 - 9,613,528 (+)Ensemblrn6Rnor6.0
Rnor_5.01611,414,640 - 11,572,157 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4168,863,537 - 8,913,459 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera166,575,743 - 6,625,300 (-)NCBICelera
RGSC_v3.1168,866,751 - 8,913,458 (+)NCBI
Cytogenetic Map16p16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
Muconic dialdehyde  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
glutamatergic synapse  (IEA,ISO)
nucleoplasm  (IEA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21423176   PMID:21926414  


Genomics

Comparative Map Data
Arhgap22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,480,222 - 8,637,823 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl168,479,956 - 8,637,822 (+)EnsemblGRCr8
mRatBN7.2168,473,806 - 8,631,552 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,476,306 - 8,631,548 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx168,600,860 - 8,650,867 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0169,745,577 - 9,795,573 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0168,595,355 - 8,645,379 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,454,269 - 9,613,508 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,486,832 - 9,613,528 (+)Ensemblrn6Rnor6.0
Rnor_5.01611,414,640 - 11,572,157 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4168,863,537 - 8,913,459 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera166,575,743 - 6,625,300 (-)NCBICelera
RGSC_v3.1168,866,751 - 8,913,458 (+)NCBI
Cytogenetic Map16p16NCBI
ARHGAP22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381048,429,831 - 48,656,265 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1048,446,036 - 48,656,265 (-)Ensemblhg38GRCh38
GRCh371049,654,079 - 49,864,310 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361049,324,085 - 49,483,144 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341049,324,085 - 49,483,144NCBI
Celera1043,239,986 - 43,398,967 (-)NCBICelera
Cytogenetic Map10q11.22-q11.23NCBI
HuRef1043,918,892 - 44,129,417 (-)NCBIHuRef
CHM1_11049,935,899 - 50,146,144 (-)NCBICHM1_1
T2T-CHM13v2.01049,275,552 - 49,505,563 (-)NCBIT2T-CHM13v2.0
Arhgap22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,935,952 - 33,091,893 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1432,935,983 - 33,091,891 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381433,213,994 - 33,369,936 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,214,026 - 33,369,934 (+)Ensemblmm10GRCm38
MGSCv371434,030,009 - 34,183,122 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361432,045,915 - 32,199,025 (+)NCBIMGSCv36mm8
Celera1429,476,997 - 29,628,675 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.15NCBI
Arhgap22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555561,501,773 - 1,588,604 (+)Ensembl
ChiLan1.0NW_0049555561,462,366 - 1,588,589 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2860,676,020 - 60,925,165 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,682,205 - 60,930,486 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01045,589,509 - 45,833,137 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ARHGAP22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128419,532 - 555,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl28419,838 - 582,548 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha28648,824 - 784,583 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.028595,180 - 731,152 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl28595,483 - 758,607 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.128394,859 - 530,643 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028436,100 - 571,773 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028561,465 - 697,162 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arhgap22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721380,366,892 - 80,562,523 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367281,573,288 - 1,765,505 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367281,633,385 - 1,765,345 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1489,113,768 - 89,331,274 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11489,113,774 - 89,331,629 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21496,946,248 - 97,088,885 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1943,140,076 - 43,349,962 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl943,316,598 - 43,349,602 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660482,901,664 - 3,117,756 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249281,265,592 - 1,433,947 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Arhgap22
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1138,942,664 - 9,098,859 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arhgap22
1593 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:56
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000035915
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16423421216278352Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16423421216278352Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421216061395Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16423433317730812Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
D16Rat83  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8168,633,842 - 8,634,057 (+)Marker Load Pipeline
mRatBN7.2168,627,567 - 8,627,782 (+)MAPPERmRatBN7.2
Rnor_6.0169,609,524 - 9,609,738NCBIRnor6.0
Rnor_5.01611,568,173 - 11,568,387UniSTSRnor5.0
RGSC_v3.4168,909,480 - 8,909,694UniSTSRGSC3.4
RGSC_v3.4168,909,479 - 8,909,694RGDRGSC3.4
Celera166,579,508 - 6,579,722UniSTS
RGSC_v3.1168,909,478 - 8,909,692RGD
RH 3.4 Map1684.5UniSTS
RH 3.4 Map1684.5RGD
SHRSP x BN Map163.4RGD
SHRSP x BN Map163.4UniSTS
Cytogenetic Map16p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 89 59 6 353 189 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000035915   ⟹   ENSRNOP00000033034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl168,588,024 - 8,637,822 (+)Ensembl
mRatBN7.2 Ensembl168,581,784 - 8,631,547 (+)Ensembl
Rnor_6.0 Ensembl169,563,218 - 9,613,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082208   ⟹   ENSRNOP00000068839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl168,512,547 - 8,637,822 (+)Ensembl
mRatBN7.2 Ensembl168,506,247 - 8,631,548 (+)Ensembl
Rnor_6.0 Ensembl169,486,832 - 9,613,528 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101853   ⟹   ENSRNOP00000096403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl168,479,956 - 8,637,822 (+)Ensembl
mRatBN7.2 Ensembl168,476,306 - 8,631,548 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104962   ⟹   ENSRNOP00000078254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl168,528,948 - 8,631,548 (+)Ensembl
RefSeq Acc Id: NM_001107297   ⟹   NP_001100767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,588,024 - 8,637,822 (+)NCBI
mRatBN7.2168,581,784 - 8,631,547 (+)NCBI
Rnor_6.0169,563,218 - 9,613,503 (+)NCBI
Rnor_5.01611,414,640 - 11,572,157 (+)NCBI
RGSC_v3.4168,863,537 - 8,913,459 (+)RGD
Celera166,575,743 - 6,625,300 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252751   ⟹   XP_006252813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,619,350 - 8,637,823 (+)NCBI
mRatBN7.2168,613,123 - 8,631,552 (+)NCBI
Rnor_6.0169,594,300 - 9,613,508 (+)NCBI
Rnor_5.01611,414,640 - 11,572,157 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600084   ⟹   XP_017455573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,482,722 - 8,637,823 (+)NCBI
mRatBN7.2168,476,445 - 8,631,552 (+)NCBI
Rnor_6.0169,454,269 - 9,613,508 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094464   ⟹   XP_038950392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,482,458 - 8,637,823 (+)NCBI
mRatBN7.2168,476,179 - 8,631,200 (+)NCBI
RefSeq Acc Id: XM_039094467   ⟹   XP_038950395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,512,394 - 8,637,823 (+)NCBI
mRatBN7.2168,504,998 - 8,631,548 (+)NCBI
RefSeq Acc Id: XM_039094469   ⟹   XP_038950397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,619,194 - 8,637,823 (+)NCBI
mRatBN7.2168,612,955 - 8,631,552 (+)NCBI
RefSeq Acc Id: XM_063275358   ⟹   XP_063131428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,480,222 - 8,637,823 (+)NCBI
RefSeq Acc Id: XM_063275359   ⟹   XP_063131429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,512,398 - 8,637,823 (+)NCBI
RefSeq Acc Id: XM_063275360   ⟹   XP_063131430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,482,722 - 8,634,022 (+)NCBI
RefSeq Acc Id: XM_063275361   ⟹   XP_063131431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,604,757 - 8,637,823 (+)NCBI
RefSeq Acc Id: NP_001100767   ⟸   NM_001107297
- Sequence:
RefSeq Acc Id: XP_006252813   ⟸   XM_006252751
- Peptide Label: isoform X5
- UniProtKB: A6KFU6 (UniProtKB/TrEMBL),   D4ABZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455573   ⟸   XM_017600084
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZKJ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033034   ⟸   ENSRNOT00000035915
Ensembl Acc Id: ENSRNOP00000068839   ⟸   ENSRNOT00000082208
RefSeq Acc Id: XP_038950392   ⟸   XM_039094464
- Peptide Label: isoform X1
- UniProtKB: A0A8I6APD0 (UniProtKB/TrEMBL),   A0A8I5ZKJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950395   ⟸   XM_039094467
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZKJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950397   ⟸   XM_039094469
- Peptide Label: isoform X6
- UniProtKB: A6KFU6 (UniProtKB/TrEMBL),   D4ABZ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096403   ⟸   ENSRNOT00000101853
Ensembl Acc Id: ENSRNOP00000078254   ⟸   ENSRNOT00000104962
RefSeq Acc Id: XP_063131428   ⟸   XM_063275358
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131430   ⟸   XM_063275360
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063131429   ⟸   XM_063275359
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063131431   ⟸   XM_063275361
- Peptide Label: isoform X8
- UniProtKB: A6KFU6 (UniProtKB/TrEMBL),   D4ABZ7 (UniProtKB/TrEMBL)
Protein Domains
PH   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTT7-F1-model_v2 AlphaFold A0A0G2JTT7 1-700 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699959
Promoter ID:EPDNEW_R10472
Type:initiation region
Name:Arhgap22_1
Description:Rho GTPase activating protein 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10473  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0169,486,804 - 9,486,864EPDNEW
RGD ID:13699949
Promoter ID:EPDNEW_R10473
Type:single initiation site
Name:Arhgap22_2
Description:Rho GTPase activating protein 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10472  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0169,563,194 - 9,563,254EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307237 AgrOrtholog
BioCyc Gene G2FUF-12093 BioCyc
Ensembl Genes ENSRNOG00000024728 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035915.4 UniProtKB/TrEMBL
  ENSRNOT00000082208 ENTREZGENE
  ENSRNOT00000082208.3 UniProtKB/TrEMBL
  ENSRNOT00000101853 ENTREZGENE
  ENSRNOT00000101853.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
KEGG Report rno:306279 UniProtKB/TrEMBL
NCBI Gene 306279 ENTREZGENE
PANTHER RHO GTPASE-ACTIVATING PROTEIN 22 UniProtKB/TrEMBL
  SPERMATHECAL PHYSIOLOGY VARIANT UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PhenoGen Arhgap22 PhenoGen
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024728 RatGTEx
SMART RhoGAP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Rho_GAP UniProtKB/TrEMBL
UniProt A0A0G2JTT7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKJ1 ENTREZGENE
  A0A8I6APD0 ENTREZGENE, UniProtKB/TrEMBL
  A6KFU6 ENTREZGENE, UniProtKB/TrEMBL
  D4ABZ7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Arhgap22  Rho GTPase activating protein 22   Arhgap22_predicted  Rho GTPase activating protein 22 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arhgap22_predicted  Rho GTPase activating protein 22 (predicted)      Symbol and Name status set to approved 70820 APPROVED