Dyrk1b (dual specificity tyrosine phosphorylation regulated kinase 1B) - Rat Genome Database

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Gene: Dyrk1b (dual specificity tyrosine phosphorylation regulated kinase 1B) Rattus norvegicus
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Symbol: Dyrk1b
Name: dual specificity tyrosine phosphorylation regulated kinase 1B
RGD ID: 1307223
Description: Predicted to enable protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in adipose tissue development and positive regulation of DNA-templated transcription. Predicted to act upstream of or within myoblast fusion. Predicted to be located in chromosome and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome 3. Orthologous to human DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b; LOC308468
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,606,743 - 92,624,089 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl192,607,303 - 92,614,744 (+)EnsemblGRCr8
mRatBN7.2183,479,168 - 83,497,011 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,479,147 - 83,487,169 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx188,889,379 - 88,897,399 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0197,347,612 - 97,355,624 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,645,238 - 90,653,258 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0185,112,819 - 85,120,840 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,112,247 - 85,120,839 (+)Ensemblrn6Rnor6.0
Rnor_5.0186,329,130 - 86,336,572 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4183,281,284 - 83,288,783 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera177,879,060 - 77,887,106 (+)NCBICelera
RGSC_v3.1183,359,284 - 83,366,556 (+)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11980910   PMID:12902328   PMID:24827035  


Genomics

Comparative Map Data
Dyrk1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,606,743 - 92,624,089 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl192,607,303 - 92,614,744 (+)EnsemblGRCr8
mRatBN7.2183,479,168 - 83,497,011 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,479,147 - 83,487,169 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx188,889,379 - 88,897,399 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0197,347,612 - 97,355,624 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,645,238 - 90,653,258 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0185,112,819 - 85,120,840 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,112,247 - 85,120,839 (+)Ensemblrn6Rnor6.0
Rnor_5.0186,329,130 - 86,336,572 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4183,281,284 - 83,288,783 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera177,879,060 - 77,887,106 (+)NCBICelera
RGSC_v3.1183,359,284 - 83,366,556 (+)NCBI
Cytogenetic Map1q21NCBI
DYRK1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381939,825,350 - 39,834,162 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1939,825,350 - 39,834,201 (-)Ensemblhg38GRCh38
GRCh371940,315,990 - 40,324,802 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,007,830 - 45,016,681 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341945,007,830 - 45,016,681NCBI
Celera1937,118,283 - 37,127,135 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1936,763,002 - 36,771,854 (-)NCBIHuRef
CHM1_11940,317,337 - 40,326,189 (-)NCBICHM1_1
T2T-CHM13v2.01942,630,272 - 42,639,084 (-)NCBIT2T-CHM13v2.0
Dyrk1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39727,878,880 - 27,896,896 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl727,878,894 - 27,886,719 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38728,179,447 - 28,197,910 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl728,179,469 - 28,187,294 (+)Ensemblmm10GRCm38
MGSCv37728,964,502 - 28,972,313 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36727,888,243 - 27,896,054 (+)NCBIMGSCv36mm8
Celera722,740,702 - 22,748,513 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map716.67NCBI
Dyrk1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555781,187,742 - 1,195,574 (+)Ensembl
ChiLan1.0NW_0049555781,187,128 - 1,195,574 (+)NCBIChiLan1.0ChiLan1.0
DYRK1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,054,312 - 46,062,601 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11947,924,968 - 47,933,257 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01936,857,223 - 36,866,099 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11945,405,063 - 45,411,483 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1945,405,431 - 45,411,387 (-)EnsemblpanPan2panpan1.1
DYRK1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,644,191 - 113,652,441 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,644,100 - 113,828,488 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1113,048,229 - 113,056,478 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01114,244,782 - 114,253,047 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1114,244,830 - 114,253,033 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,802,615 - 113,810,861 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01113,436,276 - 113,444,515 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01114,430,538 - 114,438,787 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dyrk1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,008,632 - 14,016,673 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366612,433,483 - 2,444,752 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366612,436,702 - 2,444,758 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYRK1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,305,849 - 48,314,514 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1648,305,837 - 48,314,523 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,172,231 - 44,180,912 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYRK1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1634,361,467 - 34,370,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl634,357,449 - 34,368,067 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607312,435,577 - 12,444,444 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dyrk1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462492546,748 - 55,481 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462492540,175 - 56,177 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dyrk1b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12167,794,302 - 167,802,202 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dyrk1b
142 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:78
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000026107
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026107   ⟹   ENSRNOP00000026107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl192,607,303 - 92,614,744 (+)Ensembl
mRatBN7.2 Ensembl183,479,147 - 83,487,169 (+)Ensembl
Rnor_6.0 Ensembl185,112,834 - 85,120,839 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087157   ⟹   ENSRNOP00000075476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl192,607,303 - 92,614,744 (+)Ensembl
mRatBN7.2 Ensembl183,480,016 - 83,487,169 (+)Ensembl
Rnor_6.0 Ensembl185,112,247 - 85,120,679 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095609   ⟹   ENSRNOP00000080073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl192,607,303 - 92,614,744 (+)Ensembl
mRatBN7.2 Ensembl183,479,147 - 83,487,169 (+)Ensembl
RefSeq Acc Id: NM_001107496   ⟹   NP_001100966
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,606,743 - 92,614,745 (+)NCBI
mRatBN7.2183,479,168 - 83,487,170 (+)NCBI
Rnor_6.0185,112,834 - 85,120,839 (+)NCBI
Rnor_5.0186,329,130 - 86,336,572 (+)NCBI
RGSC_v3.4183,281,284 - 83,288,783 (+)RGD
Celera177,879,060 - 77,887,106 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415859   ⟹   NP_001402788
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,607,454 - 92,614,745 (+)NCBI
mRatBN7.2183,479,879 - 83,487,170 (+)NCBI
RefSeq Acc Id: NM_001415860   ⟹   NP_001402789
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,606,743 - 92,614,745 (+)NCBI
mRatBN7.2183,479,168 - 83,487,170 (+)NCBI
RefSeq Acc Id: XM_006228622   ⟹   XP_006228684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,607,251 - 92,624,089 (+)NCBI
mRatBN7.2183,479,754 - 83,497,011 (+)NCBI
Rnor_6.0185,113,456 - 85,120,840 (+)NCBI
Rnor_5.0186,329,130 - 86,336,572 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006228623   ⟹   XP_006228685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8192,607,251 - 92,624,089 (+)NCBI
mRatBN7.2183,479,755 - 83,497,011 (+)NCBI
Rnor_6.0185,113,456 - 85,120,840 (+)NCBI
Rnor_5.0186,329,130 - 86,336,572 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001100966   ⟸   NM_001107496
- Peptide Label: isoform 3
- UniProtKB: D4ACC4 (UniProtKB/TrEMBL),   A6J9H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228684   ⟸   XM_006228622
- Peptide Label: isoform X1
- UniProtKB: D4ACC4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228685   ⟸   XM_006228623
- Peptide Label: isoform X2
- UniProtKB: D4ACC4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075476   ⟸   ENSRNOT00000087157
Ensembl Acc Id: ENSRNOP00000026107   ⟸   ENSRNOT00000026107
Ensembl Acc Id: ENSRNOP00000080073   ⟸   ENSRNOT00000095609
RefSeq Acc Id: NP_001402789   ⟸   NM_001415860
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZP97 (UniProtKB/TrEMBL),   A6J9H1 (UniProtKB/TrEMBL),   D4ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402788   ⟸   NM_001415859
- Peptide Label: isoform 1
- UniProtKB: A0A0G2KAP6 (UniProtKB/TrEMBL),   D4ACC4 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KAP6-F1-model_v2 AlphaFold A0A0G2KAP6 1-601 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689864
Promoter ID:EPDNEW_R389
Type:initiation region
Name:Dyrk1b_1
Description:dual specificity tyrosine phosphorylation regulated kinase 1B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0185,112,855 - 85,112,915EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307223 AgrOrtholog
BioCyc Gene G2FUF-60261 BioCyc
Ensembl Genes ENSRNOG00000019254 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026107 ENTREZGENE
  ENSRNOT00000026107.8 UniProtKB/TrEMBL
  ENSRNOT00000087157 ENTREZGENE
  ENSRNOT00000087157.3 UniProtKB/TrEMBL
  ENSRNOT00000095609.2 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  PKc_DYR1A/1B UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_dual-spec_kinase UniProtKB/TrEMBL
KEGG Report rno:308468 UniProtKB/TrEMBL
NCBI Gene 308468 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN KINASE UniProtKB/TrEMBL
  PTHR24058:SF12 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Dyrk1b PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019254 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2KAP6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZP97 ENTREZGENE, UniProtKB/TrEMBL
  A6J9H1 ENTREZGENE, UniProtKB/TrEMBL
  A6J9H2 ENTREZGENE, UniProtKB/TrEMBL
  D4ACC4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Dyrk1b  dual specificity tyrosine phosphorylation regulated kinase 1B  Dyrk1b  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dyrk1b  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b   Dyrk1b_predicted  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dyrk1b_predicted  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (predicted)      Symbol and Name status set to approved 70820 APPROVED