Gene: Pira2 (paired-Ig-like receptor A2) Rattus norvegicus
Analyze
Symbol:
Pira2 (Ensembl: Lilrb1)
Name:
paired-Ig-like receptor A2 (Ensembl:leukocyte immunoglobulin like receptor B1)
RGD ID:
1307219
Description:
Predicted to enable inhibitory MHC class I receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and immune response-regulating signaling pathway. Predicted to be active in plasma membrane. Orthologous to several human genes including LILRA4 (leukocyte immunoglobulin like receptor A4); LILRA6 (leukocyte immunoglobulin like receptor A6); and LILRB1 (leukocyte immunoglobulin like receptor B1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Ig-superfamily activating receptor; leukocyte immunoglobulin like receptor B3 like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like; Lilrb3; Lilrb3l; LOC361493; paired Ig-like receptor-A1; paired Ig-like receptor-A2; paired Ig-like receptor-B; Pir-A1; Pir-A2; Pirb; six Ig-like domains/type I transmembrane
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 74,283,713 - 74,338,208 (+) NCBI GRCr8 GRCr8 GRCr8 mRatBN7.2 1 65,352,125 - 65,422,842 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 65,415,946 - 65,422,853 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 1 70,804,585 - 70,870,800 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 79,223,450 - 79,293,736 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 Rnor_6.0 1 63,759,638 - 63,849,278 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 63,759,638 - 64,013,289 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 1 62,834,564 - 62,841,533 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 1 63,728,882 - 63,735,563 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 1 63,080,980 - 63,149,417 (+) NCBI Celera RGSC_v3.1 1 63,637,445 - 63,699,115 (-) NCBI Cytogenetic Map 1 q12 NCBI
JBrowse:
Imported Disease Annotations - CTD
Only show annotations with direct experimental evidence (0 objects hidden)
Pira2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Pira2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pira2 Rat 1,2-dimethylhydrazine increases expression ISO Pira2 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of LILRA6 mRNA CTD PMID:22206623 Pira2 Rat 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PIRA2 mRNA CTD PMID:32741896 Pira2 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PIRA2 mRNA CTD PMID:32741896 Pira2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pira2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pira2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Pira2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pira2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PIRA2 mRNA CTD PMID:34747641 Pira2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Pira2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pira2 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of LILRA6 mRNA CTD PMID:27914987 Pira2 Rat 4,4'-diaminodiphenylmethane increases expression ISO Pira2 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of LILRA6 mRNA CTD PMID:18648102 Pira2 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of PIRA2 mRNA CTD PMID:28959563 Pira2 Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of PIRA2 mRNA CTD PMID:30779732 Pira2 Rat antirheumatic drug decreases expression ISO LILRA6 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of LILRA6 mRNA CTD PMID:24449571 Pira2 Rat aristolochic acid A increases expression ISO LILRA6 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of LILRA6 mRNA CTD PMID:33212167 Pira2 Rat arsane affects expression ISO LILRA6 (Homo sapiens) 6480464 Arsenic affects the expression of LILRA6 mRNA CTD PMID:28793237 Pira2 Rat arsenic atom affects expression ISO LILRA6 (Homo sapiens) 6480464 Arsenic affects the expression of LILRA6 mRNA CTD PMID:28793237 Pira2 Rat benzene-1,2,4-triol decreases expression ISO LILRA6 (Homo sapiens) 6480464 hydroxyhydroquinone results in decreased expression of LILRA6 mRNA CTD PMID:39245080 Pira2 Rat benzo[a]pyrene decreases methylation ISO LILRA6 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of LILRA6 3' UTR; Benzo(a)pyrene results in decreased methylation of more ... CTD PMID:27901495 Pira2 Rat benzo[a]pyrene increases expression ISO Pira2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of LILRA6 mRNA CTD PMID:22228805 Pira2 Rat benzo[b]fluoranthene increases expression ISO Pira2 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of PIRA2 mRNA CTD PMID:26377693 Pira2 Rat beta-lapachone decreases expression ISO LILRA6 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of LILRA6 mRNA CTD PMID:38218311 Pira2 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of PIRA2 mRNA CTD PMID:26496021 Pira2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LILRA6 mRNA CTD PMID:25181051 Pira2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PIRA2 mRNA CTD PMID:30816183|PMID:32528016|PMID:34947998 Pira2 Rat cadmium atom multiple interactions ISO LILRA6 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LILRA6 more ... CTD PMID:35301059 Pira2 Rat cadmium atom multiple interactions ISO Pira2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LILRA6 more ... CTD PMID:37236586 Pira2 Rat cadmium dichloride increases expression ISO LILRA6 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of LILRA6 mRNA CTD PMID:38568856 Pira2 Rat cadmium dichloride multiple interactions ISO Pira2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LILRA6 more ... CTD PMID:37236586 Pira2 Rat cadmium dichloride multiple interactions ISO LILRA6 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LILRA6 more ... CTD PMID:35301059 Pira2 Rat carbon nanotube increases expression ISO Pira2 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of LILRA6 mRNA; Nanotubes, Carbon analog results in more ... CTD PMID:25554681 Pira2 Rat CGP 52608 multiple interactions ISO LILRA6 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to LILRA6 gene] CTD PMID:28238834 Pira2 Rat cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of PIRA2 mRNA CTD PMID:24386269 Pira2 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of PIRA2 mRNA CTD PMID:23640034|PMID:23914054 Pira2 Rat Dibutyl phosphate affects expression ISO LILRA6 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of LILRA6 mRNA CTD PMID:37042841 Pira2 Rat dioxygen decreases expression ISO Pira2 (Mus musculus) 6480464 Oxygen deficiency results in decreased expression of LILRA6 mRNA CTD PMID:24205000 Pira2 Rat furan decreases expression EXP 6480464 furan results in decreased expression of PIRA2 mRNA CTD PMID:25539665 Pira2 Rat methylmercury chloride increases expression ISO Pira2 (Mus musculus) 6480464 methylmercuric chloride results in increased expression of LILRA6 mRNA CTD PMID:19465457 Pira2 Rat nevirapine decreases expression EXP 6480464 Nevirapine results in decreased expression of PIRA2 mRNA CTD PMID:23947594 Pira2 Rat ozone multiple interactions ISO Pira2 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... CTD PMID:34911549 Pira2 Rat PCB138 multiple interactions ISO Pira2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pira2 Rat silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of PIRA2 mRNA CTD PMID:21602193 Pira2 Rat sodium arsenate decreases expression ISO Pira2 (Mus musculus) 6480464 sodium arsenate results in decreased expression of LILRA6 mRNA; sodium arsenate results in decreased expression more ... CTD PMID:39847705 Pira2 Rat sodium arsenite decreases expression ISO Pira2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of PIRA2 mRNA CTD PMID:37682722 Pira2 Rat succimer multiple interactions ISO Pira2 (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of PIRA2 mRNA; [Succimer binds more ... CTD PMID:21641980 Pira2 Rat testosterone multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of PIRA2 mRNA; [estradiol 3-benzoate co-treated more ... CTD PMID:26496021|PMID:32741896 Pira2 Rat titanium dioxide increases expression ISO Pira2 (Mus musculus) 6480464 titanium dioxide results in increased expression of LILRA6 mRNA CTD PMID:23557971 Pira2 Rat topotecan increases expression EXP 6480464 Topotecan results in increased expression of PIRA2 mRNA CTD PMID:25729387 Pira2 Rat triphenyl phosphate affects expression ISO LILRA6 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of LILRA6 mRNA CTD PMID:37042841 Pira2 Rat valproic acid increases methylation ISO LILRA6 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of LILRA6 gene CTD PMID:29154799 Pira2 Rat XL147 multiple interactions ISO Pira2 (Mus musculus) 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LILRA6 mRNA CTD PMID:27935865