Myo10 (myosin X) - Rat Genome Database

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Gene: Myo10 (myosin X) Rattus norvegicus
Analyze
Symbol: Myo10
Name: myosin X
RGD ID: 1307193
Description: Predicted to enable cytoskeletal protein binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and plus-end directed microfilament motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport; regulation of cell shape; and regulation of filopodium assembly. Predicted to act upstream of or within positive regulation of cell-cell adhesion. Predicted to be located in filopodium tip; neuron projection; and neuronal cell body. Predicted to be part of myosin complex. Predicted to be active in filopodium. Orthologous to human MYO10 (myosin X); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC310178; myosin-X; unconventional myosin-10; unconventional myosin-X; unconventionnal myosin-X
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8277,831,532 - 78,036,137 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl277,831,532 - 78,036,137 (+)EnsemblGRCr8
mRatBN7.2276,100,989 - 76,305,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx283,221,335 - 83,423,563 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0281,343,060 - 81,545,291 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0276,347,046 - 76,550,445 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0277,868,398 - 78,072,443 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl277,868,412 - 78,071,309 (+)Ensemblrn6Rnor6.0
Rnor_5.0297,588,995 - 97,790,396 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4277,183,028 - 77,385,896 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera271,812,056 - 72,011,101 (+)NCBICelera
RGSC_v3.1277,111,353 - 77,314,838 (+)NCBI
Cytogenetic Map2q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bufotalin  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP,ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
glyphosate  (EXP)
imidacloprid  (EXP)
inulin  (ISO)
Lasiocarpine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methoxyacetic acid  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mitomycin C  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenol red  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
promegestone  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell cortex  (IEA)
cytoskeleton  (IEA)
cytosol  (IEA,ISO)
filopodium  (IBA,IEA,ISO)
filopodium membrane  (IEA)
filopodium tip  (IEA,ISS)
lamellipodium  (IEA)
myosin complex  (IEA)
neuron projection  (IEA,ISO)
neuronal cell body  (IEA,ISO)
plasma membrane  (IEA,ISO)
ruffle  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12055636   PMID:16371656   PMID:16894163   PMID:20439720   PMID:23704327  


Genomics

Comparative Map Data
Myo10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8277,831,532 - 78,036,137 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl277,831,532 - 78,036,137 (+)EnsemblGRCr8
mRatBN7.2276,100,989 - 76,305,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx283,221,335 - 83,423,563 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0281,343,060 - 81,545,291 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0276,347,046 - 76,550,445 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0277,868,398 - 78,072,443 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl277,868,412 - 78,071,309 (+)Ensemblrn6Rnor6.0
Rnor_5.0297,588,995 - 97,790,396 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4277,183,028 - 77,385,896 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera271,812,056 - 72,011,101 (+)NCBICelera
RGSC_v3.1277,111,353 - 77,314,838 (+)NCBI
Cytogenetic Map2q22NCBI
MYO10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38516,661,907 - 16,936,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl516,661,907 - 16,936,288 (-)Ensemblhg38GRCh38
GRCh37516,662,016 - 16,936,397 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36516,715,016 - 16,989,385 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34516,718,412 - 16,989,139NCBI
Celera516,686,791 - 16,961,521 (-)NCBICelera
Cytogenetic Map5p15.1NCBI
HuRef516,634,005 - 16,909,126 (-)NCBIHuRef
CHM1_1516,661,893 - 16,936,226 (-)NCBICHM1_1
T2T-CHM13v2.0516,601,148 - 16,875,413 (-)NCBIT2T-CHM13v2.0
Myo10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391525,622,636 - 25,813,759 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1525,622,611 - 25,813,759 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381525,622,550 - 25,813,673 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1525,622,525 - 25,813,673 (+)Ensemblmm10GRCm38
MGSCv371525,552,305 - 25,743,426 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361525,567,651 - 25,756,950 (+)NCBIMGSCv36mm8
Celera1526,396,055 - 26,587,057 (+)NCBICelera
Cytogenetic Map15B1NCBI
cM Map159.36NCBI
Myo10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554265,727,042 - 5,885,302 (-)Ensembl
ChiLan1.0NW_0049554265,725,766 - 5,885,316 (-)NCBIChiLan1.0ChiLan1.0
MYO10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2416,899,283 - 17,169,889 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1515,052,893 - 15,323,471 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0516,969,146 - 17,239,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1516,805,022 - 17,075,001 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl516,804,216 - 17,074,534 (-)EnsemblpanPan2panpan1.1
MYO10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1486,701,907 - 86,792,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl486,596,225 - 86,792,257 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha486,115,654 - 86,310,421 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0487,234,383 - 87,429,285 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl487,233,833 - 87,429,284 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1486,757,648 - 86,953,127 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0487,010,925 - 87,189,505 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0487,850,904 - 88,046,417 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Myo10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213210,344,226 - 210,506,772 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648019,282,085 - 19,443,271 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648019,280,723 - 19,443,267 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl165,907,116 - 6,094,845 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1165,907,111 - 6,145,485 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2166,353,453 - 6,590,952 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYO10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1416,337,933 - 16,608,115 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl416,334,559 - 16,451,166 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606411,870,730 - 12,140,712 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475113,518,258 - 13,678,148 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475113,517,132 - 13,719,953 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Myo10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13155,001,294 - 155,203,732 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Myo10
2086 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:268
Count of miRNA genes:142
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000014022, ENSRNOT00000065897
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)261556902106556902Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)261051883104684275Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)261051541105724065Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)261051541105724065Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)260861391105861391Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat

Markers in Region
D2Rat204  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8277,867,083 - 77,867,304 (+)Marker Load Pipeline
mRatBN7.2276,136,547 - 76,136,768 (+)MAPPERmRatBN7.2
Rnor_6.0277,904,218 - 77,904,438NCBIRnor6.0
Rnor_5.0297,623,705 - 97,623,925UniSTSRnor5.0
RGSC_v3.4277,217,967 - 77,218,188RGDRGSC3.4
RGSC_v3.4277,217,968 - 77,218,188UniSTSRGSC3.4
Celera271,847,481 - 71,847,701UniSTS
RGSC_v3.1277,146,168 - 77,146,587RGD
SHRSP x BN Map229.7798UniSTS
SHRSP x BN Map229.7798RGD
Cytogenetic Map2q22UniSTS
RH137575  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2276,128,919 - 76,129,090 (+)MAPPERmRatBN7.2
Rnor_6.0277,896,753 - 77,896,923NCBIRnor6.0
Rnor_5.0297,616,240 - 97,616,410UniSTSRnor5.0
RGSC_v3.4277,210,340 - 77,210,510UniSTSRGSC3.4
Celera271,839,853 - 71,840,023UniSTS
RH 3.4 Map2484.6UniSTS
Cytogenetic Map2q22UniSTS
MYO10  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2276,293,717 - 76,293,853 (+)MAPPERmRatBN7.2
Rnor_6.0278,062,004 - 78,062,139NCBIRnor6.0
Rnor_5.0297,779,956 - 97,780,091UniSTSRnor5.0
RGSC_v3.4277,376,586 - 77,376,721UniSTSRGSC3.4
Celera272,001,791 - 72,001,926UniSTS
Cytogenetic Map2q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 88 59 6 352 188 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014022   ⟹   ENSRNOP00000014022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl277,831,532 - 78,034,305 (+)Ensembl
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)Ensembl
Rnor_6.0 Ensembl277,868,432 - 78,071,309 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000065897   ⟹   ENSRNOP00000063102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl277,831,532 - 78,036,137 (+)Ensembl
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)Ensembl
Rnor_6.0 Ensembl277,868,412 - 78,071,263 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102421   ⟹   ENSRNOP00000096719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl277,887,670 - 78,036,137 (+)Ensembl
mRatBN7.2 Ensembl276,157,154 - 76,303,030 (+)Ensembl
RefSeq Acc Id: NM_001401822   ⟹   NP_001388751
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,831,532 - 78,036,137 (+)NCBI
mRatBN7.2276,100,989 - 76,305,619 (+)NCBI
RefSeq Acc Id: XM_039102213   ⟹   XP_038958141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,993,376 - 78,034,943 (+)NCBI
mRatBN7.2276,262,832 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102214   ⟹   XP_038958142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,976,203 - 78,034,943 (+)NCBI
mRatBN7.2276,243,775 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102215   ⟹   XP_038958143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,976,673 - 78,034,943 (+)NCBI
mRatBN7.2276,248,112 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102216   ⟹   XP_038958144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,980,339 - 78,034,943 (+)NCBI
mRatBN7.2276,249,792 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102218   ⟹   XP_038958146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,980,012 - 78,034,943 (+)NCBI
mRatBN7.2276,248,895 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_063281749   ⟹   XP_063137819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,980,339 - 78,034,943 (+)NCBI
RefSeq Acc Id: XM_063281750   ⟹   XP_063137820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,995,586 - 78,034,943 (+)NCBI
Ensembl Acc Id: ENSRNOP00000014022   ⟸   ENSRNOT00000014022
Ensembl Acc Id: ENSRNOP00000063102   ⟸   ENSRNOT00000065897
RefSeq Acc Id: XP_038958142   ⟸   XM_039102214
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958143   ⟸   XM_039102215
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958146   ⟸   XM_039102218
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958144   ⟸   XM_039102216
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958141   ⟸   XM_039102213
- Peptide Label: isoform X1
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096719   ⟸   ENSRNOT00000102421
RefSeq Acc Id: NP_001388751   ⟸   NM_001401822
- UniProtKB: D3ZJP6 (UniProtKB/Swiss-Prot),   A0A8I6AR40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137819   ⟸   XM_063281749
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137820   ⟸   XM_063281750
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
Protein Domains
FERM   IQ   Myosin motor   MyTH4   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJP6-F1-model_v2 AlphaFold D3ZJP6 1-2060 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691202
Promoter ID:EPDNEW_R1726
Type:initiation region
Name:Myo10_1
Description:myosin X
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0277,868,434 - 77,868,494EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307193 AgrOrtholog
BioCyc Gene G2FUF-53948 BioCyc
Ensembl Genes ENSRNOG00000010161 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065897 ENTREZGENE
  ENSRNOT00000065897.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot
  1.20.5.170 UniProtKB/Swiss-Prot
  1.20.5.190 UniProtKB/Swiss-Prot
  1.20.58.530 UniProtKB/Swiss-Prot
  1.20.80.10 UniProtKB/Swiss-Prot
  1.25.40.530 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  3.40.850.10 UniProtKB/Swiss-Prot
  6.20.240.20 UniProtKB/Swiss-Prot
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro Actin_motor_Myosin UniProtKB/Swiss-Prot
  Band_41_domain UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot
  MYO10_CC UniProtKB/Swiss-Prot
  Myosin_head_motor_dom UniProtKB/Swiss-Prot
  MyoX_FERM_C UniProtKB/Swiss-Prot
  MyoX_N_SH3 UniProtKB/Swiss-Prot
  MYSc_Myo10 UniProtKB/Swiss-Prot
  MyTH4_dom UniProtKB/Swiss-Prot
  MyTH4_dom_sf UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
NCBI Gene 310178 ENTREZGENE
PANTHER AGAP003327-PA UniProtKB/Swiss-Prot
  UNCONVENTIONAL MYOSIN-X UniProtKB/Swiss-Prot
Pfam FERM_M UniProtKB/Swiss-Prot
  MYO10_CC UniProtKB/Swiss-Prot
  Myosin_head UniProtKB/Swiss-Prot
  MyTH4 UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
  PF00612 UniProtKB/Swiss-Prot
  RA_2 UniProtKB/Swiss-Prot
  SH3_19 UniProtKB/Swiss-Prot
PhenoGen Myo10 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot
PROSITE FERM_3 UniProtKB/Swiss-Prot
  MYOSIN_MOTOR UniProtKB/Swiss-Prot
  MYTH4 UniProtKB/Swiss-Prot
  PH_DOMAIN UniProtKB/Swiss-Prot
  PS50096 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010161 RatGTEx
SMART B41 UniProtKB/Swiss-Prot
  MYSc UniProtKB/Swiss-Prot
  MyTH4 UniProtKB/Swiss-Prot
  SM00015 UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6AR40 ENTREZGENE, UniProtKB/TrEMBL
  A6JMW4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZJP6 ENTREZGENE
  D3ZZ73 ENTREZGENE
  F1M9V6 ENTREZGENE, UniProtKB/TrEMBL
  MYO10_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Myo10  myosin X   Myo10_predicted  myosin X (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Myo10_predicted  myosin X (predicted)      Symbol and Name status set to approved 70820 APPROVED