Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of LEPROTL1 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LEPROTL1 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LEPROTL1 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of LEPROTL1 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LEPROTL1 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of LEPROTL1 mRNA | CTD | PMID:21179406 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LEPROTL1 mRNA | CTD | PMID:28628672 | acrolein | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of LEPROTL1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of LEPROTL1 mRNA | CTD | PMID:32699268 | all-trans-retinoic acid | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of LEPROTL1 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of LEPROTL1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of LEPROTL1 mRNA | CTD | PMID:32699268 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of LEPROTL1 mRNA | CTD | PMID:30779732 | atrazine | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of LEPROTL1 mRNA | CTD | PMID:22378314 | benzene | increases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Benzene results in increased expression of LEPROTL1 mRNA | CTD | PMID:19162166 and PMID:20036648 | benzo[a]pyrene | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LEPROTL1 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LEPROTL1 mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LEPROTL1 mRNA | CTD | PMID:25181051 | bisphenol F | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LEPROTL1 mRNA | CTD | PMID:28628672 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of LEPROTL1 mRNA | CTD | PMID:24136188 | cadmium atom | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LEPROTL1 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of LEPROTL1 promoter | CTD | PMID:22457795 | cadmium dichloride | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LEPROTL1 mRNA | CTD | PMID:35301059 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of LEPROTL1 mRNA | CTD | PMID:33453195 | carbon nanotube | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of LEPROTL1 mRNA | CTD | PMID:25620056 | crocidolite asbestos | decreases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of LEPROTL1 mRNA | CTD | PMID:29279043 | dexamethasone | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LEPROTL1 mRNA | CTD | PMID:28628672 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of LEPROTL1 mRNA | CTD | PMID:21266533 | fenthion | decreases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of LEPROTL1 mRNA | CTD | PMID:34813904 | folic acid | decreases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of LEPROTL1 mRNA | CTD | PMID:25629700 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of LEPROTL1 mRNA | CTD | PMID:22061828 | indometacin | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LEPROTL1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LEPROTL1 protein | CTD | PMID:32959892 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of LEPROTL1 mRNA | CTD | PMID:24136188 | leflunomide | increases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | leflunomide results in increased expression of LEPROTL1 mRNA | CTD | PMID:28988120 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of LEPROTL1 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of LEPROTL1 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | LEPROTL1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of LEPROTL1 mRNA more ... | CTD | PMID:32699268 | p-toluidine | decreases expression | EXP | | 6480464 | 4-toluidine results in decreased expression of LEPROTL1 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LEPROTL1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of LEPROTL1 mRNA | CTD | PMID:26690555 | paracetamol | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LEPROTL1 mRNA | CTD | PMID:21420995 | pirinixic acid | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LEPROTL1 mRNA | CTD | PMID:18301758 and PMID:23811191 | rac-lactic acid | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LEPROTL1 mRNA | CTD | PMID:30851411 | rotenone | increases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Rotenone results in increased expression of LEPROTL1 mRNA | CTD | PMID:33512557 | rotenone | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Rotenone results in increased expression of LEPROTL1 mRNA | CTD | PMID:32937126 | sunitinib | increases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of LEPROTL1 mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | ISO | Leprotl1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LEPROTL1 mRNA | CTD | PMID:31919559 | valproic acid | affects expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LEPROTL1 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LEPROTL1 mRNA | CTD | PMID:23034163 | zinc atom | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Zinc deficiency results in decreased expression of LEPROTL1 mRNA | CTD | PMID:22171008 | zinc(0) | decreases expression | ISO | LEPROTL1 (Homo sapiens) | 6480464 | Zinc deficiency results in decreased expression of LEPROTL1 mRNA | CTD | PMID:22171008 | |