Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Slco5a1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SLCO5A1 mRNA | CTD | PMID:29097150 | Slco5a1 | Rat | 17beta-estradiol | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SLCO5A1 mRNA | CTD | PMID:31614463 | Slco5a1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Slco5a1 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of SLCO5A1 mRNA | CTD | PMID:38648751 | Slco5a1 | Rat | 3-iodothyronamine | affects uptake | ISO | SLCO5A1 (Homo sapiens) | 6480464 | SLCO5A1 mRNA affects the uptake of 3-iodothyronamine | CTD | PMID:19074582 | Slco5a1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | SLCO5A1 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of SLCO5A1 gene | CTD | PMID:31601247 | Slco5a1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Slco5a1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of SLCO5A1 gene | CTD | PMID:31683443 | Slco5a1 | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of SLCO5A1 mRNA | CTD | PMID:24780913 | Slco5a1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25825206|PMID:30047161 | Slco5a1 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:31881176 | Slco5a1 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:28959563 | Slco5a1 | Rat | aflatoxin B1 | decreases methylation | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SLCO5A1 gene | CTD | PMID:27153756 | Slco5a1 | Rat | all-trans-retinoic acid | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SLCO5A1 mRNA | CTD | PMID:33167477 | Slco5a1 | Rat | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of SLCO5A1 mRNA | CTD | PMID:35163327 | Slco5a1 | Rat | amiodarone | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of SLCO5A1 mRNA | CTD | PMID:19774075 | Slco5a1 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of SLCO5A1 mRNA | CTD | PMID:30047161 | Slco5a1 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of SLCO5A1 mRNA | CTD | PMID:30779732 | Slco5a1 | Rat | benzo[a]pyrene | decreases methylation | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SLCO5A1 exon | CTD | PMID:27901495 | Slco5a1 | Rat | benzo[a]pyrene | affects methylation | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLCO5A1 3' UTR; Benzo(a)pyrene affects the methylation of SLCO5A1 5' more ... | CTD | PMID:27901495 | Slco5a1 | Rat | benzo[e]pyrene | increases methylation | ISO | SLCO5A1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SLCO5A1 intron | CTD | PMID:30157460 | Slco5a1 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of SLCO5A1 mRNA | CTD | PMID:34319233 | Slco5a1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25181051|PMID:41034487 | Slco5a1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SLCO5A1 mRNA | CTD | PMID:30816183 | Slco5a1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SLCO5A1 gene | CTD | PMID:28505145 | Slco5a1 | Rat | CGP 52608 | multiple interactions | ISO | SLCO5A1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLCO5A1 gene] | CTD | PMID:28238834 | Slco5a1 | Rat | crocidolite asbestos | decreases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of SLCO5A1 mRNA | CTD | PMID:23917077 | Slco5a1 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SLCO5A1 mRNA | CTD | PMID:26577399 | Slco5a1 | Rat | dimethylarsinic acid | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slco5a1 | Rat | ethyl methanesulfonate | decreases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of SLCO5A1 mRNA | CTD | PMID:23649840 | Slco5a1 | Rat | fulvestrant | multiple interactions | ISO | SLCO5A1 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of SLCO5A1 gene | CTD | PMID:31601247 | Slco5a1 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25539665 | Slco5a1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SLCO5A1 mRNA | CTD | PMID:33387578 | Slco5a1 | Rat | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Arbutin results in decreased expression of SLCO5A1 mRNA | CTD | PMID:17103032 | Slco5a1 | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of SLCO5A1 mRNA | CTD | PMID:20080153 | Slco5a1 | Rat | lipopolysaccharide | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of SLCO5A1 mRNA | CTD | PMID:35811015 | Slco5a1 | Rat | lipopolysaccharide | multiple interactions | ISO | SLCO5A1 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SLCO5A1 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Slco5a1 | Rat | methapyrilene | increases methylation | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SLCO5A1 intron | CTD | PMID:30157460 | Slco5a1 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of SLCO5A1 mRNA | CTD | PMID:30047161 | Slco5a1 | Rat | methyl methanesulfonate | decreases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of SLCO5A1 mRNA | CTD | PMID:23649840 | Slco5a1 | Rat | methylarsonic acid | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slco5a1 | Rat | methylmercury chloride | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of SLCO5A1 mRNA | CTD | PMID:28001369 | Slco5a1 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SLCO5A1 gene | CTD | PMID:33148267 | Slco5a1 | Rat | nickel atom | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Nickel results in increased expression of SLCO5A1 mRNA | CTD | PMID:24768652|PMID:25583101 | Slco5a1 | Rat | niclosamide | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of SLCO5A1 mRNA | CTD | PMID:36318118 | Slco5a1 | Rat | okadaic acid | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of SLCO5A1 mRNA | CTD | PMID:38832940 | Slco5a1 | Rat | ozone | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Slco5a1 | Rat | paracetamol | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SLCO5A1 mRNA | CTD | PMID:29067470 | Slco5a1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SLCO5A1 mRNA | CTD | PMID:33387578 | Slco5a1 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SLCO5A1 gene | CTD | PMID:33148267 | Slco5a1 | Rat | pinostrobin | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | pinostrobin results in increased expression of SLCO5A1 protein | CTD | PMID:37164308 | Slco5a1 | Rat | pioglitazone | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO5A1 mRNA | CTD | PMID:27935865 | Slco5a1 | Rat | progesterone | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | NCOA2 protein affects the reaction [Progesterone results in increased expression of SLCO5A1 mRNA] | CTD | PMID:17556502 | Slco5a1 | Rat | progesterone | increases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | Progesterone results in increased expression of SLCO5A1 mRNA | CTD | PMID:17556502 | Slco5a1 | Rat | quercetin | increases uptake | ISO | SLCO5A1 (Homo sapiens) | 6480464 | SLCO5A1 protein results in increased uptake of Quercetin | CTD | PMID:24947867 | Slco5a1 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | SLCO5A1 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SLCO5A1 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Slco5a1 | Rat | silicon dioxide | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of SLCO5A1 mRNA | CTD | PMID:25351596 | Slco5a1 | Rat | silver atom | decreases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | Silver results in decreased expression of SLCO5A1 mRNA | CTD | PMID:27131904 | Slco5a1 | Rat | silver(0) | decreases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | Silver results in decreased expression of SLCO5A1 mRNA | CTD | PMID:27131904 | Slco5a1 | Rat | sodium arsenate | increases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SLCO5A1 mRNA | CTD | PMID:30953684 | Slco5a1 | Rat | sodium arsenate | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slco5a1 | Rat | sodium arsenite | decreases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25879800 | Slco5a1 | Rat | sodium arsenite | decreases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SLCO5A1 mRNA | CTD | PMID:37682722 | Slco5a1 | Rat | sodium arsenite | multiple interactions | ISO | Slco5a1 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slco5a1 | Rat | sodium arsenite | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SLCO5A1 mRNA | CTD | PMID:38568856 | Slco5a1 | Rat | sunitinib | decreases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SLCO5A1 mRNA | CTD | PMID:31533062 | Slco5a1 | Rat | temozolomide | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of SLCO5A1 mRNA | CTD | PMID:31758290 | Slco5a1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:34492290 | Slco5a1 | Rat | titanium dioxide | decreases expression | ISO | Slco5a1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:29264374 | Slco5a1 | Rat | titanium dioxide | decreases methylation | ISO | Slco5a1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SLCO5A1 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Slco5a1 | Rat | xylitol | increases expression | ISO | SLCO5A1 (Homo sapiens) | 6480464 | Xylitol results in increased expression of SLCO5A1 mRNA | CTD | PMID:32275922 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















