Ankrd52 (ankyrin repeat domain 52) - Rat Genome Database

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Gene: Ankrd52 (ankyrin repeat domain 52) Rattus norvegicus
Analyze
Symbol: Ankrd52
Name: ankyrin repeat domain 52
RGD ID: 1307124
Description: Orthologous to human ANKRD52 (ankyrin repeat domain 52); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362811; RGD1307124; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C; similar to RIKEN cDNA G431002C21
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,390,730 - 1,410,139 (+)NCBIGRCr8
mRatBN7.27806,829 - 820,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7806,767 - 820,481 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,567,577 - 3,582,239 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,443,559 - 5,458,220 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,742,291 - 5,756,002 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,795,888 - 2,809,538 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,795,901 - 2,813,887 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,774,352 - 2,788,002 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,668,981 - 1,682,632 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,669,009 - 1,685,795 (+)NCBI
Celera7680,321 - 693,973 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ankrd52
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,390,730 - 1,410,139 (+)NCBIGRCr8
mRatBN7.27806,829 - 820,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7806,767 - 820,481 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,567,577 - 3,582,239 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,443,559 - 5,458,220 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,742,291 - 5,756,002 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,795,888 - 2,809,538 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,795,901 - 2,813,887 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,774,352 - 2,788,002 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,668,981 - 1,682,632 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,669,009 - 1,685,795 (+)NCBI
Celera7680,321 - 693,973 (+)NCBICelera
Cytogenetic Map7q11NCBI
ANKRD52
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,237,807 - 56,258,384 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,237,807 - 56,258,384 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,631,591 - 56,652,168 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,917,858 - 54,938,410 (-)NCBINCBI36Build 36hg18NCBI36
Celera1256,284,485 - 56,305,031 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1253,670,584 - 53,691,211 (-)NCBIHuRef
CHM1_11256,598,982 - 56,619,532 (-)NCBICHM1_1
T2T-CHM13v2.01256,205,432 - 56,226,014 (-)NCBIT2T-CHM13v2.0
Ankrd52
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,212,993 - 128,229,875 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,212,984 - 128,244,573 (+)EnsemblGRCm39 Ensembl
GRCm3810128,377,124 - 128,394,006 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,377,115 - 128,408,704 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,814,180 - 127,831,062 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,780,073 - 127,796,955 (+)NCBIMGSCv36mm8
Celera10130,765,399 - 130,782,262 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.54NCBI
Ankrd52
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,854,442 - 3,867,787 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,849,400 - 3,867,167 (-)NCBIChiLan1.0ChiLan1.0
ANKRD52
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,073,266 - 38,094,298 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,069,573 - 38,091,069 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,656,107 - 32,677,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,908,491 - 32,929,072 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,908,720 - 32,923,738 (+)Ensemblpanpan1.1panPan2
ANKRD52
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110562,510 - 574,641 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10546,964 - 574,744 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10620,638 - 638,429 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010565,862 - 583,657 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10566,285 - 583,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110543,311 - 561,099 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010786,294 - 804,082 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010910,377 - 928,168 (-)NCBIUU_Cfam_GSD_1.0
Ankrd52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,205,100 - 58,224,540 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646651,031 - 663,043 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646645,695 - 665,133 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD52
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,637,613 - 21,657,045 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,638,034 - 21,657,091 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,011,022 - 23,029,958 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANKRD52
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,191,840 - 52,216,505 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,197,178 - 52,216,362 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,774,050 - 193,794,575 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankrd52
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,748,915 - 11,765,778 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,749,003 - 11,767,752 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ankrd52
57 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:62
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000047462
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 33 33 22 11 22 3 67 29 32 3
Low 10 24 19 8 19 8 8 7 6 9 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000047462   ⟹   ENSRNOP00000045243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7806,767 - 820,481 (+)Ensembl
Rnor_6.0 Ensembl72,795,901 - 2,813,887 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115276   ⟹   ENSRNOP00000082123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7807,183 - 820,481 (+)Ensembl
RefSeq Acc Id: NM_001191875   ⟹   NP_001178804
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,391,372 - 1,405,023 (+)NCBI
mRatBN7.27806,829 - 820,481 (+)NCBI
Rnor_6.072,795,888 - 2,809,538 (+)NCBI
Rnor_5.072,774,352 - 2,788,002 (+)NCBI
Celera7680,321 - 693,973 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263699   ⟹   XP_063119769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,390,730 - 1,410,139 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178804 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119769 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84865 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045243
  ENSRNOP00000045243.5
  ENSRNOP00000082123.1
Reference Protein Sequences
RefSeq Acc Id: NP_001178804   ⟸   NM_001191875
- Sequence:
RefSeq Acc Id: ENSRNOP00000045243   ⟸   ENSRNOT00000047462
RefSeq Acc Id: ENSRNOP00000082123   ⟸   ENSRNOT00000115276
RefSeq Acc Id: XP_063119769   ⟸   XM_063263699
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ACT4-F1-model_v2 AlphaFold D4ACT4 1-1084 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694934
Promoter ID:EPDNEW_R5459
Type:initiation region
Name:Ankrd52_1
Description:ankyrin repeat domain 52
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,795,819 - 2,795,879EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307124 AgrOrtholog
BioCyc Gene G2FUF-35374 BioCyc
Ensembl Genes ENSRNOG00000030597 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047462 ENTREZGENE
  ENSRNOT00000047462.6 UniProtKB/TrEMBL
  ENSRNOT00000115276.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
NCBI Gene 362811 ENTREZGENE
PANTHER MOLTING PROTEIN MLT-4 UniProtKB/TrEMBL
  SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT C UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
PhenoGen Ankrd52 PhenoGen
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030597 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A0A8I6G706_RAT UniProtKB/TrEMBL
  D4ACT4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ankrd52  ankyrin repeat domain 52   Ankrd52_predicted  ankyrin repeat domain 52 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ankrd52_predicted  ankyrin repeat domain 52 (predicted)  RGD1307124_predicted  similar to RIKEN cDNA G431002C21 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1307124_predicted  similar to RIKEN cDNA G431002C21 (predicted)  LOC362811_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362811_predicted  similar to RIKEN cDNA G431002C21 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL