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Gene: Niban2 (niban apoptosis regulator 2) Rattus norvegicus

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Symbol:

Niban2

Name:

niban apoptosis regulator 2

RGD ID:

1307018

Description:

Predicted to enable transcription coactivator activity. Predicted to be involved in several processes, including gonadotropin secretion; negative regulation of apoptotic process; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in adherens junction; cytosol; and nucleus. Orthologous to human NIBAN2 (niban apoptosis regulator 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aconitine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Fam129b; family with sequence similarity 129, member B; LOC362115; Meg-3; niban-like protein 1; RGD1307018; similar to RIKEN cDNA 9130404D14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NIBAN2 (niban apoptosis regulator 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Niban2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Niban2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NIBAN2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NIBAN2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Niban2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NIBAN2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NIBAN2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Niban2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Niban2 (niban apoptosis regulator 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NIBAN2 (niban apoptosis regulator 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Niban2 (niban apoptosis regulator 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fam129ba (family with sequence similarity 129 member Ba)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fam129bb (family with sequence similarity 129 member Bb)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fam129bb (family with sequence similarity 129 member Bb)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	niban2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	niban2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	36,572,356 - 36,621,968 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	36,572,377 - 36,621,967 (+)	Ensembl				GRCr8
mRatBN7.2	3	16,174,674 - 16,224,293 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	16,174,659 - 16,224,293 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	19,242,343 - 19,292,066 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	27,827,347 - 27,877,070 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	26,079,098 - 26,128,723 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	11,921,715 - 11,971,327 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	11,921,715 - 11,971,327 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	17,257,993 - 17,307,290 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	11,862,604 - 11,912,117 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	10,914,173 - 10,963,784 (+)	NCBI		Celera
RGSC_v3.1	3	11,759,166 - 11,808,481 (+)	NCBI
Cytogenetic Map	3	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dimethoxyphenol (ISO)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

aconitine (EXP)

aldrin (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

chlordecone (ISO)

chloroethene (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cytarabine (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

diethylstilbestrol (ISO)

dioxygen (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

ethanol (ISO)

FR900359 (ISO)

furan (EXP)

furfural (ISO)

inulin (ISO)

ivermectin (ISO)

ketoconazole (ISO)

lead diacetate (ISO)

lipopolysaccharide (ISO)

methoxychlor (EXP)

methylparaben (ISO)

paracetamol (EXP,ISO)

perfluorodecanoic acid (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenanthrene (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

propylparaben (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium fluoride (ISO)

Soman (EXP)

sunitinib (ISO)

tamoxifen (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

gonadotropin secretion (IEA,ISO)

negative regulation of apoptotic process (IEA,ISO,ISS)

negative regulation of cell population proliferation (IEA,ISO)

negative regulation of DNA biosynthetic process (IEA,ISO)

negative regulation of DNA-templated transcription (IEA,ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

Cellular Component

adherens junction (IEA,ISO,ISS)

cytoplasm (IEA,ISO)

cytosol (IEA,ISO,ISS)

membrane (IEA)

nucleoplasm (ISO)

nucleus (ISO,ISS)

plasma membrane (IEA,ISO)

Molecular Function

protein binding (ISO)

transcription coactivator activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:14602737	PMID:17569660	PMID:18628527	PMID:19056867	PMID:20032057	PMID:20179190	PMID:21148485	PMID:23533145	PMID:25468996

Genomics

Comparative Map Data

Niban2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	36,572,356 - 36,621,968 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	36,572,377 - 36,621,967 (+)	Ensembl				GRCr8
mRatBN7.2	3	16,174,674 - 16,224,293 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	16,174,659 - 16,224,293 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	19,242,343 - 19,292,066 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	27,827,347 - 27,877,070 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	26,079,098 - 26,128,723 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	11,921,715 - 11,971,327 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	11,921,715 - 11,971,327 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	17,257,993 - 17,307,290 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	11,862,604 - 11,912,117 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	10,914,173 - 10,963,784 (+)	NCBI		Celera
RGSC_v3.1	3	11,759,166 - 11,808,481 (+)	NCBI
Cytogenetic Map	3	p11	NCBI

NIBAN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	127,505,343 - 127,579,031 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	127,505,339 - 127,578,989 (-)	Ensembl			hg38	GRCh38
GRCh37	9	130,267,622 - 130,341,310 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	129,307,439 - 129,381,089 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	127,347,172 - 127,410,909	NCBI
Celera	9	100,918,505 - 100,992,132 (-)	NCBI		Celera
Cytogenetic Map	9	q34.11	NCBI
HuRef	9	99,883,553 - 99,957,416 (-)	NCBI		HuRef
CHM1_1	9	130,418,921 - 130,492,461 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	139,712,305 - 139,786,022 (-)	NCBI		T2T-CHM13v2.0

Niban2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	32,766,146 - 32,815,265 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	32,766,126 - 32,815,266 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	32,876,134 - 32,925,253 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	32,876,114 - 32,925,254 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	32,731,654 - 32,780,773 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	32,698,234 - 32,747,258 (+)	NCBI		MGSCv36	mm8
Celera	2	32,583,095 - 32,632,235 (+)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	22.09	NCBI

Niban2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	1,072,243 - 1,119,620 (+)	Ensembl
ChiLan1.0	NW_004955419	1,089,602 - 1,119,620 (+)	NCBI	ChiLan1.0	ChiLan1.0

NIBAN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	11,784,223 - 11,849,159 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	11,787,847 - 11,851,506 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	98,625,411 - 98,689,077 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	127,299,475 - 127,362,552 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	127,299,475 - 127,371,459 (-)	Ensembl			panPan2	panpan1.1

NIBAN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	55,802,010 - 55,853,960 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	55,802,014 - 55,852,540 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	54,994,587 - 55,046,576 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	56,723,425 - 56,775,654 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	56,723,409 - 56,775,654 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	55,483,586 - 55,535,366 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	55,798,215 - 55,850,400 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	55,889,577 - 55,941,107 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Niban2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	195,452,680 - 195,500,994 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	15,221,241 - 15,269,521 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	15,221,207 - 15,269,515 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NIBAN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	268,010,297 - 268,065,930 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	268,010,297 - 268,066,022 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	301,920,994 - 301,974,856 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NIBAN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	10,556,661 - 10,621,281 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	10,556,650 - 10,621,589 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666079	5,595,833 - 5,661,162 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Niban2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	7,951,934 - 7,996,256 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624760	7,951,943 - 7,996,260 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Niban2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	2,707,490 - 2,756,425 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Niban2
202 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	503
Count of miRNA genes:	245
Interacting mature miRNAs:	297
Transcripts:	ENSRNOT00000021689
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29056275	47904329	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450811	Scl73	Serum cholesterol level QTL 73	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat
10450808	Scl72	Serum cholesterol level QTL 72	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450806	Scl71	Serum cholesterol level QTL 71	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	6125437	51125437	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	30832384	44921701	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	36721849	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	6556347	51556347	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	36101403	81101403	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	29056275	47904329	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	36425116	81425116	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat

Markers in Region

RH134452

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	16,224,357 - 16,224,541 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	11,971,392 - 11,971,575	NCBI	Rnor6.0
Rnor_5.0	3	17,307,355 - 17,307,538	UniSTS	Rnor5.0
RGSC_v3.4	3	11,912,182 - 11,912,365	UniSTS	RGSC3.4
Celera	3	10,963,849 - 10,964,032	UniSTS
RH 3.4 Map	3	74.7	UniSTS
Cytogenetic Map	3	p11	UniSTS

RH134590

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	16,223,944 - 16,224,128 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	11,970,979 - 11,971,162	NCBI	Rnor6.0
Rnor_5.0	3	17,306,942 - 17,307,125	UniSTS	Rnor5.0
RGSC_v3.4	3	11,911,769 - 11,911,952	UniSTS	RGSC3.4
Celera	3	10,963,436 - 10,963,619	UniSTS
RH 3.4 Map	3	81.6	UniSTS
Cytogenetic Map	3	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	10	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC142126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC104682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC168248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021689 ⟹ ENSRNOP00000021689

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	36,572,377 - 36,621,967 (+)	Ensembl
mRatBN7.2 Ensembl	3	16,174,659 - 16,224,293 (+)	Ensembl
Rnor_6.0 Ensembl	3	11,921,715 - 11,971,327 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096288 ⟹ ENSRNOP00000087586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	16,204,359 - 16,224,293 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101921 ⟹ ENSRNOP00000080933

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	16,204,504 - 16,224,293 (+)	Ensembl

RefSeq Acc Id:

NM_001109885 ⟹ NP_001103355

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	36,572,356 - 36,621,968 (+)	NCBI
mRatBN7.2	3	16,174,674 - 16,224,293 (+)	NCBI
Rnor_6.0	3	11,921,715 - 11,971,327 (+)	NCBI
Rnor_5.0	3	17,257,993 - 17,307,290 (+)	NCBI
RGSC_v3.4	3	11,862,604 - 11,912,117 (+)	RGD
Celera	3	10,914,173 - 10,963,784 (+)	RGD

Sequence:

show sequence

GGGAGCCTGGGCGCGGGCTAGAGAGGCAGCAGCGCCGGCGGGAGGGACGCAGCGGGGATCTCGG
TACCAGCGCAGAGGAGCCTAGGCGGCAGCCGGGCTACGGGCGGCGGGAGCGGGGCCTGCGGACT
CCATGGCGCCAGCGGCGTCCGTCTGAGTAGCGGTGGGCGGATCCGGCTTGGCTTCTTCTCGCCA
TGGGAGACGTACTGTCCACACACCTGGATGACGCGCGGCGCCAGAACATCGCAGAGAAAACTGA
GAAGATCCTGAGAGAGTTCCTTCGTTTCTATGAGGACCAGTATGGTGTCTCCCTCTTCAACAGC
ATGCGCCATGAGATTGAGGGCACCGGGCCTCCGCAGGCACAGCTGCTCTGGCGCAAGGTGCCCC
TGGATGAACGCATCATCTTCTCCGGGAACCTTTTCCAGTACCAGGAAGACAATAAGAAGTGGAG
AAACCGCTTCAGCCTGGTGCCCCATAACTATGGGCTGGTGCTGTATGAGAACAAAGTGGCCTAT
GAGCGGCAGATACCACCCCGGGCCGTCATCAACAGTGCTGGCTACAAGGTTCTCACCTCTCTCG
ACCAGTACCTGGAGCTTGTGGGGAATTCCCTACCAGGGACCACGTCGAAATCAGGCTCCACCCC
CATCCTTAAGTGCCCAACGCAGTTCCCTCTCATCCTGTGGCATCCGTATGCCCGGCACTATTAC
TTCTGCATGATGACTGAAGCGGAACAGGACAAGTGGCAGGCGGTGCTTCAGGATTGCGTCCGAC
ACTGCAACAACGGGATCCCGGAGAACTCCAAGGTGGAGGGCCCAGCATTCACAGATGCCATCCG
TATGTACCGCCAGTCGAAGGAGCAGTACGGCACCTGGGAAATGCTATGTGGGAACGAGGTGCAG
ATCCTAAGCAACCTGGTGATGGAGGAGCTGGGCCCAGCGCTGAAGACAGAGCTTGGGCCACGGC
TGAAGGGAAAGCCTCAGGAGCGGCAGCGACAGTGGATCCAGATCTCGGATGCTGTGTACCGCCT
GGTATTTGAACAGGCCAAGGTGCACTTTGAGGAGGTGCTGTGTAAGCTGCAGTTGGCCCGGCCA
GCCATGGAGGCAGTTATCCGTACAGACATGGACCAGATCATCACCTCCAAGGAGCATCTGGCCA
GCAAGATCCGAGCCTTCATCCTCCCCAAGGCAGAGGTGTGCGTGAGGAACCATGTCCAGCCCTA
CATCCCATCCATCCTAGAGGCTCTGATGGTGCCCACCAGCCAGGGCTTCACCGAGGTGCGGGAC
GTCTTCTTCAAAGAGGTCACAGACATGAATCTGAATGTCATCAACGAGGGTGGCATCGACAAGC
TGGGCGAGTACATGGAGAAGCTGTCCCAACTGGCGTACCACCCCCTGAAGATGCAGAGCTGCTA
CGAGAAGATGGAGCCGCTGCGGCTCGATGGGCTGCAGCAGCGCTTTGACGTGTCTAGCACTTCT
GTGTTCAAGCAGCGAGCCCAGATCCACATGCGAGAGCAAATGGACAATGCTGTGTACACCTTCG
AAACCCTCCTGCACCAAGAGCTGGGGAAGGGACCCACCAAGGAGGAGCTGTGCAAGTCCATCCA
GCGGATTCTGGAGCGGGTGCTGAAGAAATACGACTATGACAGCAGTTCTGTGCGCAAGAGATTC
TTCCGAGAGGCGCTGCTGCAGATCACCATTCCCTTCCTGCTCAAAAAGCTGGCCCCCACCTGCA
AGTCGGAGCTGCCACGCTTCCAGGAGCTGATCTTTGAAGACTTTGCCAGGTTCATCCTGGTGGA
GAACACATACGAGGAGGTGGTGCTGCAGACGGTCATGAAGGACATCCTGCAGGCTGTGAAGGAG
GCGGCAGTGCAGCGCAAACATAACCTCTACCGGGACAGCGTGGTTCTGCATAACAGCGACCCCA
ATCTACACCTGCTGGCTGAGGGTGCACCCATTGACTGGGGCGAACAGTATGGTGACGGCGGTGA
CGGCAGTGACAGTGGTGGCAGCCCCTGCCCCTCCGAAGCAGCCACCCTCACAGAAAAGCGCAGG
CGTGCCAAGCAGGTGGTGTCCGTGGTCCAGGACGAGGAGTCAGGGCTGCCCTTTGAGGCTGGCT
CTGAACCGCCATCACCTGCATCCCCGGACAATGTCACTGAGCTCCGAGGCCTGTTGGCCCAGGA
TCTGCAGGCTGAAAGTTCTCCACCAGCCAGCCCCCTCCTCAATGGGGCCCCGGTCCAAGAGAGC
CCCCAGCCCATGACAGTCCTAGAGGCTTCGCCACCAGCCTCACCCCTCCGGCACCTCCCACCTG
GAAAAGCTGTGGACCTTGAGCCCCCTAAACCCAGTGATCAAGAGACCGGGGAGAAAGTGTCTAG
CCCTGGTAGCCGTCCCCCCATCCATACCACCACCGAGGACAGCGCAGGAGTGCAGACGGAGTTC
TAGGCATGGCCTCCCAGCTTCTGTTGGACTCTGCACTGGGGCGCTTCTCCTTGGGCACCGCAGC
CTCATCTCTGGGGAGGGGTACTCCAGTCTGTGCCTTGTGGAGAAGGTAGCTGGGGTGGTGTGGC
ACCTCCAGGGGTCTGGCCTATCCAAGTCACTTTATGGGGTTTAGTACACCTGTTACTGCCTCGT
TTTCTGTGGGCTGGTCTCCGATGCTAGGTCTGGTTTTGAGGGTTTCCTCTTTGTGCAAGGGGCT
GGGGAGCCCCTCCATCCTGCCCTCACGCTGTTACCTGTTTCCCTCCCGGTGGTTCTTGACGGAG
GTAGATGAAAGCATTGGTGCAACTCATGTCTAGGAAGCTGGAAAGCTGTCATCTCACTCTGGGG
CCCCTTGCCTAAGTGGCAAGGAAGAGGCGGAGGCCTGGCCTCTGTCCTGCCCACTCCCTGCAGG
TCCCAAGGTTAGACAGACACTAGAGTGCTCACTGGCCACACTTTGCGGGTTACTGGTGCGGGAG
GGCGGGGCTTAGGGGTCTGGTAGGGGAGCGATGGAATGAGAAAGGCCCAGAATGTGTTAAGTCT
GTGCAGGGGAAGTGTCCTGAGGGGAGGGTCTTTGGGAGGGTCGAAGGCCAGGATGGCAAAGTGA
AGGTAGCTGAGGTTGCAGTCTTGGGTGCCCACTGCTGTGCATCTGTCTGGTTATCTACCCCTAC
TTTGGGCTGACAACTGCAGGGTTGGGTGTAGGCTGTCTCACTGCATGCCGGGAAGCTGGAGAAG
CTCCACGGGAACATTGAGGGCCATGGCTTTGAGACACTGCAGAGCATCCTTGGTCTCTGTAACT
CACGTCACCTAACCCTGACAATTCCAGACCCTTCTTCCATTGTCCTTGTGAACCATTTGGGCTT
ATCTTTCCCTCTTAGTCGCAAGGGTCAAACCAAGGGTCAGTCAAGTAGATGACTGTCACCTTGG
GCCTCCCCAGACTCTGCTGCCGGGGTTGGGAGACCAAAGTAGAAACTGCCACTACAAGGCCCCA
GGATGAGGTCTCTGTTCTGTGGACCTGCTCCCCAGATACAGGCCTCAGACCCATAGGACGTGGC
CGGTGCTCAGGGACACCCAGTCCCCGGCCCTCACTCCATCGAGTACTGACTTCTTTCTCTAGTG
CCTTGGGGGTCTCCATCCTTCCAGTTATGGTATGAAGAATCTATGCAAACTGTATAAGCTTCTG
CTCACCAATAAACGCTTTATTTAAAGCTCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001103355	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI04683	(Get FASTA)	NCBI Sequence Viewer
	AAI68248	(Get FASTA)	NCBI Sequence Viewer
	B4F7E8	(Get FASTA)	NCBI Sequence Viewer
	EDL93203	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021689
	ENSRNOP00000021689.4

RefSeq Acc Id:

NP_001103355 ⟸ NM_001109885

- UniProtKB:

B4F7E8 (UniProtKB/Swiss-Prot), A0A8I5ZQW0 (UniProtKB/TrEMBL), A0A8I6GG50 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGDVLSTHLDDARRQNIAEKTEKILREFLRFYEDQYGVSLFNSMRHEIEGTGPPQAQLLWRKVP
LDERIIFSGNLFQYQEDNKKWRNRFSLVPHNYGLVLYENKVAYERQIPPRAVINSAGYKVLTSL
DQYLELVGNSLPGTTSKSGSTPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCVR
HCNNGIPENSKVEGPAFTDAIRMYRQSKEQYGTWEMLCGNEVQILSNLVMEELGPALKTELGPR
LKGKPQERQRQWIQISDAVYRLVFEQAKVHFEEVLCKLQLARPAMEAVIRTDMDQIITSKEHLA
SKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNVINEGGIDK
LGEYMEKLSQLAYHPLKMQSCYEKMEPLRLDGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTF
ETLLHQELGKGPTKEELCKSIQRILERVLKKYDYDSSSVRKRFFREALLQITIPFLLKKLAPTC
KSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSVVLHNSDP
NLHLLAEGAPIDWGEQYGDGGDGSDSGGSPCPSEAATLTEKRRRAKQVVSVVQDEESGLPFEAG
SEPPSPASPDNVTELRGLLAQDLQAESSPPASPLLNGAPVQESPQPMTVLEASPPASPLRHLPP
GKAVDLEPPKPSDQETGEKVSSPGSRPPIHTTTEDSAGVQTEF

hide sequence

Ensembl Acc Id:

ENSRNOP00000021689 ⟸ ENSRNOT00000021689

Ensembl Acc Id:

ENSRNOP00000087586 ⟸ ENSRNOT00000096288

Ensembl Acc Id:

ENSRNOP00000080933 ⟸ ENSRNOT00000101921

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B4F7E8-F1-model_v2	AlphaFold	B4F7E8	1-747	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691997

Promoter ID:

EPDNEW_R2522

Type:

initiation region

Name:

Fam129b_1

Description:

family with sequence similarity 129, member B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	11,921,734 - 11,921,794	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307018	AgrOrtholog
BioCyc Gene	G2FUF-50117	BioCyc
Ensembl Genes	ENSRNOG00000015845	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000021689	ENTREZGENE
	ENSRNOT00000021689.6	UniProtKB/Swiss-Prot
Gene3D-CATH	2.30.29.30	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7460725	IMAGE-MGC_LOAD
InterPro	Niban-like	UniProtKB/Swiss-Prot
	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PH_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:362115	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:125259	IMAGE-MGC_LOAD
NCBI Gene	362115	ENTREZGENE
PANTHER	PROTEIN NIBAN 2	UniProtKB/Swiss-Prot
	PTHR14392	UniProtKB/Swiss-Prot
PhenoGen	Niban2	PhenoGen
PROSITE	PH_DOMAIN	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000015845	RatGTEx
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZQW0	ENTREZGENE
	A0A8I6GG50	ENTREZGENE
	B4F7E8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-29	Niban2	niban apoptosis regulator 2	Fam129b	family with sequence similarity 129, member B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Fam129b	family with sequence similarity 129, member B	RGD1307018	similar to RIKEN cDNA 9130404D14	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1307018	similar to RIKEN cDNA 9130404D14	RGD1307018_predicted	similar to RIKEN cDNA 9130404D14 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1307018_predicted	similar to RIKEN cDNA 9130404D14 (predicted)	LOC362115_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362115_predicted	similar to RIKEN cDNA 9130404D14 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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