Cfl2 (cofilin 2) - Rat Genome Database

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Gene: Cfl2 (cofilin 2) Rattus norvegicus
Analyze
Symbol: Cfl2
Name: cofilin 2
RGD ID: 1306982
Description: Predicted to enable actin filament binding activity. Predicted to be involved in several processes, including actin filament fragmentation; actin filament severing; and positive regulation of actin filament depolymerization. Predicted to act upstream of or within actin filament depolymerization; muscle cell cellular homeostasis; and sarcomere organization. Predicted to be located in Z disc. Predicted to be active in actin cytoskeleton and cytoplasm. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Orthologous to human CFL2 (cofilin 2); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cofilin 2, muscle; cofilin-2; LOC366624
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,090,843 - 78,094,888 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,090,843 - 78,094,888 (-)EnsemblGRCr8
mRatBN7.2672,355,664 - 72,359,709 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,355,664 - 72,359,674 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx672,776,952 - 72,780,998 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,083,627 - 73,087,673 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,512,645 - 72,516,691 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0675,759,140 - 75,763,185 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,759,140 - 75,763,185 (-)Ensemblrn6Rnor6.0
Rnor_5.0685,300,272 - 85,304,317 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,203,408 - 75,207,425 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,199,891 - 71,203,936 (-)NCBICelera
RGSC_v3.1675,206,505 - 75,210,540 (-)NCBI
Cytogenetic Map6q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (EXP)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
coumarin  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gardiquimod  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosomorpholine  (EXP)
nickel atom  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenol red  (ISO)
picoxystrobin  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
saxitoxin  (ISO)
SB 431542  (ISO)
selenomethionine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
Triptolide  (EXP)
trovafloxacin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin cytoskeleton  (IBA,IEA)
cytoplasm  (IBA)
I band  (IEA,ISO)
Z disc  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11809832   PMID:17160903   PMID:19023180   PMID:19752190   PMID:22343409   PMID:23533145   PMID:23580065   PMID:24598388   PMID:24840128   PMID:25373779   PMID:31400829   PMID:31505169  
PMID:35352799  


Genomics

Comparative Map Data
Cfl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,090,843 - 78,094,888 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,090,843 - 78,094,888 (-)EnsemblGRCr8
mRatBN7.2672,355,664 - 72,359,709 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,355,664 - 72,359,674 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx672,776,952 - 72,780,998 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,083,627 - 73,087,673 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,512,645 - 72,516,691 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0675,759,140 - 75,763,185 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,759,140 - 75,763,185 (-)Ensemblrn6Rnor6.0
Rnor_5.0685,300,272 - 85,304,317 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,203,408 - 75,207,425 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,199,891 - 71,203,936 (-)NCBICelera
RGSC_v3.1675,206,505 - 75,210,540 (-)NCBI
Cytogenetic Map6q23NCBI
CFL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381434,709,113 - 34,714,593 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1434,709,113 - 34,714,823 (-)Ensemblhg38GRCh38
GRCh371435,178,319 - 35,183,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,249,343 - 34,253,657 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341434,249,400 - 34,253,649NCBI
Celera1415,043,756 - 15,048,197 (-)NCBICelera
Cytogenetic Map14q13.1NCBI
HuRef1415,292,957 - 15,297,397 (-)NCBIHuRef
CHM1_11435,178,338 - 35,182,776 (-)NCBICHM1_1
T2T-CHM13v2.01428,908,282 - 28,913,764 (-)NCBIT2T-CHM13v2.0
Cfl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391254,905,602 - 54,910,065 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1254,905,594 - 54,909,662 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381254,858,815 - 54,862,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1254,858,809 - 54,862,877 (-)Ensemblmm10GRCm38
MGSCv371255,959,804 - 55,963,864 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361255,776,952 - 55,781,012 (-)NCBIMGSCv36mm8
Celera1256,156,897 - 56,160,843 (-)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1223.75NCBI
Cfl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540926,246,369 - 26,250,082 (+)Ensembl
ChiLan1.0NW_00495540926,247,050 - 26,250,082 (+)NCBIChiLan1.0ChiLan1.0
CFL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,028,367 - 36,032,840 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11435,245,162 - 35,249,428 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01415,468,532 - 15,473,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11433,655,744 - 33,659,478 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1433,655,744 - 33,659,473 (-)EnsemblpanPan2panpan1.1
CFL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1813,578,152 - 13,582,408 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl813,580,360 - 13,582,442 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha813,375,939 - 13,380,225 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0813,685,460 - 13,689,787 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl813,685,460 - 13,689,655 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1813,386,351 - 13,390,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0813,451,695 - 13,455,979 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0813,741,046 - 13,745,331 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cfl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864045,440,643 - 45,442,426 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364948,946,442 - 8,948,358 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364948,946,442 - 8,948,320 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl765,090,276 - 65,094,512 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1765,090,170 - 65,094,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,919,806 - 69,923,077 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CFL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12411,541,226 - 11,545,690 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2411,543,638 - 11,544,335 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666053494,119 - 498,564 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cfl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248382,031,895 - 2,037,728 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248382,032,658 - 2,036,893 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cfl2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1768,222,476 - 68,226,535 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cfl2
46 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1050
Count of miRNA genes:315
Interacting mature miRNAs:435
Transcripts:ENSRNOT00000072589
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
D14S1319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2672,355,707 - 72,355,877 (+)MAPPERmRatBN7.2
Rnor_6.0675,759,184 - 75,759,353NCBIRnor6.0
Rnor_5.0685,300,316 - 85,300,485UniSTSRnor5.0
RGSC_v3.4675,203,424 - 75,203,593UniSTSRGSC3.4
Celera671,199,935 - 71,200,104UniSTS
Cytogenetic Map6q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 91 59 6 355 191 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000072589   ⟹   ENSRNOP00000067174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,090,843 - 78,094,888 (-)Ensembl
mRatBN7.2 Ensembl672,355,664 - 72,359,674 (-)Ensembl
Rnor_6.0 Ensembl675,759,140 - 75,763,185 (-)Ensembl
RefSeq Acc Id: NM_001108982   ⟹   NP_001102452
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8678,090,843 - 78,094,888 (-)NCBI
mRatBN7.2672,355,664 - 72,359,709 (-)NCBI
Rnor_6.0675,759,140 - 75,763,185 (-)NCBI
Rnor_5.0685,300,272 - 85,304,317 (-)NCBI
RGSC_v3.4675,203,408 - 75,207,425 (-)RGD
Celera671,199,891 - 71,203,936 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240104   ⟹   XP_006240166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8678,092,296 - 78,094,694 (-)NCBI
mRatBN7.2672,355,670 - 72,359,518 (-)NCBI
Rnor_6.0675,759,146 - 75,763,007 (-)NCBI
Rnor_5.0685,300,272 - 85,304,317 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001102452 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240166 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03417 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000067174
  ENSRNOP00000067174.1
RefSeq Acc Id: NP_001102452   ⟸   NM_001108982
- UniProtKB: M0RC65 (UniProtKB/TrEMBL),   A6HBL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240166   ⟸   XM_006240104
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000067174   ⟸   ENSRNOT00000072589
Protein Domains
ADF-H

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RC65-F1-model_v2 AlphaFold M0RC65 1-166 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694600
Promoter ID:EPDNEW_R5124
Type:initiation region
Name:Cfl2_1
Description:cofilin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0675,763,115 - 75,763,175EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306982 AgrOrtholog
BioCyc Gene G2FUF-37500 BioCyc
Ensembl Genes ENSRNOG00000045892 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072589 ENTREZGENE
  ENSRNOT00000072589.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/TrEMBL
InterPro Actin-bd_cofilin/tropomyosin UniProtKB/TrEMBL
  ADF-H/Gelsolin-like_dom UniProtKB/TrEMBL
  ADF/Cofilin/Destrin UniProtKB/TrEMBL
KEGG Report rno:366624 UniProtKB/TrEMBL
NCBI Gene 366624 ENTREZGENE
PANTHER PTHR11913 UniProtKB/TrEMBL
Pfam Cofilin_ADF UniProtKB/TrEMBL
PhenoGen Cfl2 PhenoGen
PRINTS COFILIN UniProtKB/TrEMBL
PROSITE ADF_H UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045892 RatGTEx
SMART ADF UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/TrEMBL
UniProt A6HBL2 ENTREZGENE, UniProtKB/TrEMBL
  M0RC65 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Cfl2  cofilin 2  Cfl2  cofilin 2, muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cfl2  cofilin 2, muscle   Cfl2_predicted  cofilin 2, muscle (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cfl2_predicted  cofilin 2, muscle (predicted)      Symbol and Name status set to approved 70820 APPROVED