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Gene: Cmbl (carboxymethylenebutenolidase homolog) Rattus norvegicus

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Symbol:

Cmbl

Name:

carboxymethylenebutenolidase homolog

RGD ID:

1306952

Description:

Predicted to enable hydrolase activity. Predicted to be located in cytosol. Orthologous to human CMBL (carboxymethylenebutenolidase homolog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Ab2-225; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase-like; liver regeneration-related protein LRRG072; LOC310201; MGC95111; RGD1306952; similar to Ab2-225

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CMBL (carboxymethylenebutenolidase homolog)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cmbl (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cmbl (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CMBL (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CMBL (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cmbl (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CMBL (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CMBL (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cmbl (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cmbl (carboxymethylenebutenolidase homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Cmbl (carboxymethylenebutenolidase homolog)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CMBL (carboxymethylenebutenolidase homolog)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cmbl (carboxymethylenebutenolidase homolog (Pseudomonas))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	AIM2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector)
Saccharomyces cerevisiae (baker's yeast):	AIM2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cmbl	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	84,280,128 - 84,301,878 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	84,242,512 - 84,301,880 (+)	Ensembl				GRCr8
mRatBN7.2	2	82,569,257 - 82,591,007 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	82,571,888 - 82,591,009 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	89,611,485 - 89,633,262 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	87,733,060 - 87,754,837 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	82,789,344 - 82,811,125 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	84,645,084 - 84,666,836 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	84,645,084 - 84,666,835 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	104,317,820 - 104,339,572 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	83,659,292 - 83,681,042 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	78,093,828 - 78,114,831 (+)	NCBI		Celera
RGSC_v3.1	2	83,617,546 - 83,626,004 (+)	NCBI
Cytogenetic Map	2	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-methylcholine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

actinomycin D (ISO)

adefovir pivoxil (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (EXP,ISO)

amiodarone (EXP,ISO)

ampicillin (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Bufotalin (ISO)

butanal (ISO)

Butylbenzyl phthalate (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chloroacetaldehyde (ISO)

chlorpyrifos (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

clofibrate (EXP,ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dioxygen (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethanol (ISO)

fenofibrate (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

glafenine (EXP)

ibuprofen (EXP,ISO)

ifosfamide (ISO)

inulin (ISO)

ivermectin (ISO)

L-ethionine (EXP)

lead diacetate (ISO)

levofloxacin (EXP)

lipopolysaccharide (ISO)

maneb (ISO)

menadione (ISO)

mercury atom (ISO)

mercury(0) (ISO)

Mesaconitine (EXP)

metformin (EXP)

methapyrilene (EXP)

metronidazole (EXP)

morphine (EXP)

Muraglitazar (EXP)

N-nitrosodiethylamine (ISO)

N-nitrosomorpholine (EXP)

nefazodone (EXP)

neomycin (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

nimesulide (EXP)

nitrofen (EXP)

Nutlin-3 (ISO)

okadaic acid (ISO)

omeprazole (EXP)

ozone (ISO)

paracetamol (ISO)

paraquat (ISO)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (EXP,ISO)

progesterone (ISO)

quercetin (ISO)

resveratrol (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

Tesaglitazar (EXP)

testosterone (EXP,ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

troglitazone (EXP,ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (EXP)

vinclozolin (EXP)

zinc protoporphyrin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytosol (IEA,ISO,ISS)

Molecular Function

hydrolase activity (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:12477932	PMID:19056867	PMID:23376485

Genomics

Comparative Map Data

Cmbl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	84,280,128 - 84,301,878 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	84,242,512 - 84,301,880 (+)	Ensembl				GRCr8
mRatBN7.2	2	82,569,257 - 82,591,007 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	82,571,888 - 82,591,009 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	89,611,485 - 89,633,262 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	87,733,060 - 87,754,837 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	82,789,344 - 82,811,125 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	84,645,084 - 84,666,836 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	84,645,084 - 84,666,835 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	104,317,820 - 104,339,572 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	83,659,292 - 83,681,042 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	78,093,828 - 78,114,831 (+)	NCBI		Celera
RGSC_v3.1	2	83,617,546 - 83,626,004 (+)	NCBI
Cytogenetic Map	2	q23	NCBI

CMBL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	10,277,595 - 10,307,902 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	10,275,875 - 10,307,974 (-)	Ensembl			hg38	GRCh38
GRCh37	5	10,277,707 - 10,308,014 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	10,330,707 - 10,361,168 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	5	10,315,760 - 10,346,293 (-)	NCBI		Celera
Cytogenetic Map	5	p15.2	NCBI
HuRef	5	10,262,174 - 10,292,589 (-)	NCBI		HuRef
CHM1_1	5	10,277,580 - 10,308,025 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	10,216,896 - 10,247,204 (-)	NCBI		T2T-CHM13v2.0

Cmbl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	31,565,314 - 31,590,266 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	31,565,535 - 31,590,265 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	31,565,342 - 31,590,119 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	31,565,389 - 31,590,119 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	31,498,667 - 31,519,874 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	31,513,494 - 31,534,708 (+)	NCBI		MGSCv36	mm8
Celera	15	32,260,559 - 32,283,934 (+)	NCBI		Celera
Cytogenetic Map	15	B2	NCBI
cM Map	15	13.0	NCBI

Cmbl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	144,997 - 166,970 (-)	Ensembl
ChiLan1.0	NW_004955426	146,749 - 166,922 (-)	NCBI	ChiLan1.0	ChiLan1.0

CMBL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	10,523,400 - 10,552,808 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	8,677,006 - 8,706,474 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	10,594,567 - 10,623,214 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	10,451,378 - 10,481,731 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	10,451,369 - 10,481,731 (-)	Ensembl			panPan2	panpan1.1

CMBL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	4,008,022 - 4,031,637 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	4,021,118 - 4,033,904 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	8,510,530 - 8,534,153 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	3,910,437 - 3,934,077 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	3,910,479 - 3,934,068 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	3,962,357 - 3,985,932 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	3,941,665 - 3,965,258 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	4,172,202 - 4,195,845 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cmbl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	237,013,266 - 237,031,583 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936643	2,371,187 - 2,386,228 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936643	2,371,191 - 2,389,506 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CMBL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	72,170,885 - 72,204,364 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	72,170,813 - 72,204,695 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

CMBL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	9,816,762 - 9,847,077 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	9,814,074 - 9,846,278 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666064	18,696,945 - 18,729,179 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cmbl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	7,630,779 - 7,648,996 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624751	7,630,773 - 7,652,328 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cmbl
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	149,233,354 - 149,250,729 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cmbl
201 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	51
Count of miRNA genes:	47
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000015448
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578777	Stresp15	Stress response QTL 15	2	0.05	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	2	61556902	106556902	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1598865	Bp296	Blood pressure QTL 296	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	82947902	127947902	Rat
1578772	Stresp14	Stress response QTL 14	5	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	2	84056790	132859658	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	40306867	124537199	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
61465	Bp13	Blood pressure QTL 13	3.3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	78269809	104744824	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	41801363	104744824	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	44904355	85286097	Rat
2317058	Aia13	Adjuvant induced arthritis QTL 13	2.9		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	2	78269809	123269809	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	44537979	112567334	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
5684990	Bmd82	Bone mineral density QTL 82	2.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	2	61051541	105724065	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1359034	Bp274	Blood pressure QTL 274			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	51266859	96266859	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
631500	Bp99	Blood pressure QTL 99	2.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	61051883	104684275	Rat
61392	Bp6	Blood pressure QTL 6	7		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	82214549	127214549	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
5684996	Bmd85	Bone mineral density QTL 85	4.7	0.024	tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	2	61051541	105724065	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
1558648	Smcn1	Smooth muscle cell number QTL 1		0.039	blood vessel smooth muscle cell quantity (VT:0010525)	aorta smooth muscle cell count per unit vessel length (CMO:0001646)	2	60861391	105861391	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	38426449	111295694	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	44904355	89904355	Rat
61438	Cia7	Collagen induced arthritis QTL 7	4.6	0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	2	61051541	143746880	Rat

Markers in Region

RH128841

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	82,590,801 - 82,590,964 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,666,630 - 84,666,792	NCBI	Rnor6.0
Rnor_5.0	2	104,339,366 - 104,339,528	UniSTS	Rnor5.0
RGSC_v3.4	2	83,680,837 - 83,680,999	UniSTS	RGSC3.4
Celera	2	78,114,626 - 78,114,788	UniSTS
RH 3.4 Map	2	516.7	UniSTS
Cytogenetic Map	2	q22	UniSTS

RH129775

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	82,590,802 - 82,590,963 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,666,631 - 84,666,791	NCBI	Rnor6.0
Rnor_5.0	2	104,339,367 - 104,339,527	UniSTS	Rnor5.0
RGSC_v3.4	2	83,680,838 - 83,680,998	UniSTS	RGSC3.4
Celera	2	78,114,627 - 78,114,787	UniSTS
RH 3.4 Map	2	517.1	UniSTS
Cytogenetic Map	2	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	78	59	6	342	178	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY325197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF556107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ209709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015448 ⟹ ENSRNOP00000015448

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	84,283,200 - 84,301,879 (+)	Ensembl
mRatBN7.2 Ensembl	2	82,572,352 - 82,591,007 (+)	Ensembl
Rnor_6.0 Ensembl	2	84,645,084 - 84,666,835 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118086 ⟹ ENSRNOP00000079112

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	84,242,512 - 84,301,880 (+)	Ensembl
mRatBN7.2 Ensembl	2	82,571,888 - 82,591,009 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000145367 ⟹ ENSRNOP00000101821

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	84,279,552 - 84,301,880 (+)	Ensembl

RefSeq Acc Id:

NM_001008770 ⟹ NP_001008770

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	84,280,128 - 84,301,878 (+)	NCBI
mRatBN7.2	2	82,569,257 - 82,591,007 (+)	NCBI
Rnor_6.0	2	84,645,084 - 84,666,835 (+)	NCBI
Rnor_5.0	2	104,317,820 - 104,339,572 (+)	NCBI
RGSC_v3.4	2	83,659,292 - 83,681,042 (+)	RGD
Celera	2	78,093,828 - 78,114,831 (+)	RGD

Sequence:

show sequence

GCTCTTCACCATTAGACAAGCCTGACGTCAAGACCCCAATGGCTAACGAAGCTAACCCTTGCCC
ATGTGACATTGGTCACAGGCTAGACTATGGTGGCATGGGCCAGGAAGTTCAGGTTGAGCACATC
AAGGCATATGTCACCCGGTCCCCTGTGGATGCAGGCAAAGCTGTGATTGTTGTCCAGGATATAT
TTGGCTGGCAGCTGTCCAACACCAGGTATATGGCTGACATGATTGCTGGAAATGGATACACAAC
TATTGTCCCAGACTTCTTTGTGGGTCAAGAGCCATGGGACCCGGCTGGTGATTGGTCCACCTTC
CCTGAGTGGTTGAAATCAAGAAATGCCAGAAAAATCAACCGAGAGGTTGATGCTGTCTTGAGGT
ATCTGAAACAACAGTGTCATGCCCAGAAGATTGGCATTGTGGGCTTCTGCTGGGGGGGTATTGT
GGTGCACCACGTGATGACGACATATCCAGAAGTCAGAGCGGGGGTGTCTGTCTATGGTATCATC
AGAGATTCTGAAGATGTTTATAATTTGAAGAACCCAACGTTGTTTATCTTTGCAGAAAATGATG
CTGTGATTCCACTTGAGCAGGTTTCTATACTGATCCAGAAGCTTAAAGAACACTGCATAGTTAA
TTACCAAGTTAAGACATTTTCTGGGCAAACTCATGGCTTTGTGCATCGGAAGAGAGAAGACTGC
TCCCCTGCAGACAAACCCTACATTGAGGAAGCGAGGAGGAATCTCATCGAATGGCTGAACAAGT
ATATTTAACAGCACTCAAGCACAAATTTTGAATAATTAAATTGACCCGAATAATTAACCATCTC
CTAAAATTCTCCTGAAACATACAGTAGGAACTAAATGATCAATATCTGTAAGACTTAAATGATA
GCATAACTAATTATTAGGGGAACCTGGGGCCATTCAGGGACCAGCTAGATTCTCAGATATGGCC
TTACCTTGGTAATTTGTTAACATGTACAAACCCAGGAAGATCTTGAGTTGTCTCTATGTGTATT
CAATCTCCCCTAGTGAAGTTCAATTCTGCACTTCAGTGTAAGCAGTGTTGACATTCAGTTCTCA
CCACTCTAACTATTCAACCTAATAAAGTGATTTTTAAAACTTGAAAAAAAAAAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006232097 ⟹ XP_006232159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	84,281,133 - 84,301,878 (+)	NCBI
mRatBN7.2	2	82,572,006 - 82,591,007 (+)	NCBI
Rnor_6.0	2	84,646,229 - 84,666,836 (+)	NCBI
Rnor_5.0	2	104,317,820 - 104,339,572 (+)	NCBI

Sequence:

show sequence

TGGTTTTTTTTTTTCTTCTTCTCCTATTTCTTTTGGACAACTTCATTGTGTGATCGGACTTCTG
AGCTACGCAAATCCTCAGAGCTTCAAATCAGGAAAACTATACTTGGAGACATGCTCTATGACTG
TGTCTGACTTCCAGAGAGCAGGGAAAGTGATAGAGTTCTACTCCTGAAAGACTGTTTTCCACAA
AAGATGAACATTCACCCAGGTGTAAACAACCGAGGGTTTGTGATAGTCATGACAGAGGGGACGG
ATGTCCTAGCTGACTCAAAAAAAGTTGTCAGAAAGTGCAGACCTATGTGCAGCAAGGGAAGACC
CCAGGGAGATGCCTATGACAAAGGAGATATGGGAAATCCTTGGAGAGGTTGAGGGAGCCCTTGA
AATTTGCACATCACACCTATAATAGGAATCCTCAGAGTTTTATTTTGAAAAACCTAGACTGTGC
TCAAGCTCCCTGTGCAGCCAGGGGCAGCCTTGACCTTTTCACCCTTCATCTTCTCAGTGTTCAG
ATTACAGGTCTATCTCTCCATGCCCTATTTGGGGGTCTGGAGATTGAGCCCAGGGTTTCACGAA
TGCCAGATGAGCACTCCCTCCTCCAGCAGAGTGACCCCAGCCCACCTGGTTCTTGGCCTTGTAA
TTTATAGGGATTTGCCTGTGAGAGGCAGGCTGGTAGGAGCAACAGATGTCCTACTACAGGAGAA
AGCCTGTGATTTATATATTTGCAGTATCTCCCATGAACGATTATGGGGGAAATCTAGCATTCTC
TGTCAATAGCCATTACACCCTTGCCAGAAGACATTATCATCAGGGTGTCCTTCTTAGGACAATG
GTACCACAACGAACTCCCTGACTTTAGGAGGCTCTGCCAGTGGGGATTATGGACCTGCTCTAAG
GGTGGATGTAGCCTCAAACACACAGTTAATGAGCCTGCCCCAACCTGAGAGGAACAGAAAGCCT
GCCAGTCCTATGAAAGACCTGATATTGTGCAGAAGAAACCACGCCTCAATGCAGAGTGCCCTTT
CTCTGTGGCTCACTCTCCGGCCTTATTCCGTGTATTTGCATTTTGCAATTCTTTGTAGGTCATG
GGCTACTGGTAGGCTGATAGATTTCCAAACAATGTCCTGCCTGTTATAATTAATCTCCTTCCTG
CTTCCATTGAGAAGAAACTTTGTATCCATGTGAACTTCATCTCACCTTCTGGAGGGCTTGTATT
CCAGCCAGTTGCAGCATCTCCCCCTTTCTCTCCTGTCACCCCAGGTGTGAACTTACTGTGAACT
ACGGCTATGGCAGAGTACGGAATGTTCTTCCCACAGGTGGACTTCTAGAAAGAATTGCATAAAG
TATTCTAAGCAAATGTACCCCCAAAGCAAGGACATGAAGGGACGTCCTGGCATGTCCACGTTAT
GTTTGTAGGAAAGGAAAAGAAAGGCCTGGGAGGAATATTCTAGGCTCTTTTTGCATGACTAAAG
GTGGTAAGATATAGCACCAGAGGCCTTTCCTTGTCCTTTATTTGCTTAAGCTAACCATAAATGT
CACCTCATGTTTTGTTTGCTTTAGTAATCTTGAGCGGGCGCTTTGTACTCCTTTGAGCTTGGAG
ACCTGAAGTCCCATGATTTGTTCCCACTCAGATCATTTGATCCTGGAGACTTAGCCTCAGGGGC
CACAGGGCCCATGGATCATTTTTAGTCTGTATAGGAGTGAGGTCTTTGCTTTATCCTGAAGCTC
GCCTTCTAGAAAATGTATCATGGGGAAAAGCAAAAATCCTGGAGGCAGACCCAGAAAACACGGG
CTGCCAAGGGTCAAGCATGTATTCTTGATTCTTAGCCTGAACCCCCACAGGCCTGTCCGTGGGT
AGAAACTGCTTGCCCTGTCCAGAGTACACTTGGCTCCTGCTTCTTAGACTGGGCTCAGCGGTTG
AGACCATGTGAAAGAGCTGGGCAGGACTCCAGCCTTCCACATGTGGCGTTCTTGGGCCTATGTT
GGCTCTACCCCATTCTGTGGGAGAAAAACCTTGGCTCTCCTGGATGTAAAAATTCCTTTTGTAA
TTGGAGCTCGAGTCGGAAAAGCCTGTTGCCAGCACCTTCGAAGGGACTAGATTCCTTTGGGTCT
TCCCAGCAGAGTCCAGCCTGACGTCAAGACCCCAATGGCTAACGAAGCTAACCCTTGCCCATGT
GACATTGGTCACAGGCTAGACTATGGTGGCATGGGCCAGGAAGTTCAGGTTGAGCACATCAAGG
CATATGTCACCCGGTCCCCTGTGGATGCAGGCAAAGCTGTGATTGTTGTCCAGGATATATTTGG
CTGGCAGCTGTCCAACACCAGGTATATGGCTGACATGATTGCTGGAAATGGATACACAACTATT
GTCCCAGACTTCTTTGTGGGTCAAGAGCCATGGGACCCGGCTGGTGATTGGTCCACCTTCCCTG
AGTGGTTGAAATCAAGAAATGCCAGAAAAATCAACCGAGAGGTTGATGCTGTCTTGAGGTATCT
GAAACAACAGTGTCATGCCCAGAAGATTGGCATTGTGGGCTTCTGCTGGGGGGGTATTGTGGTG
CACCACGTGATGACGACATATCCAGAAGTCAGAGCGGGGGTGTCTGTCTATGGTATCATCAGAG
ATTCTGAAGATGTTTATAATTTGAAGAACCCAACGTTGTTTATCTTTGCAGAAAATGATGCTGT
GATTCCACTTGAGCAGGTTTCTATACTGATCCAGAAGCTTAAAGAACACTGCATAGTTAATTAC
CAAGTTAAGACATTTTCTGGGCAAACTCATGGCTTTGTGCATCGGAAGAGAGAAGACTGCTCCC
CTGCAGACAAACCCTACATTGAGGAAGCGAGGAGGAATCTCATCGAATGGCTGAACAAGTATAT
TTAACAGCACTCAAGCACAAATTTTGAATAATTAAATTGACCCGAATAATTAACCATCTCCTAA
AATTCTCCTGAAACATACAGTAGGAACTAAATGATCAATATCTGTAAGACTTAAATGATAGCAT
AACTAATTATTAGGGGAACCTGGGGCCATTCAGGGACCAGCTAGATTCTCAGATATGGCCTTAC
CTTGGTAATTTGTTAACATGTACAAACCCAGGAAGATCTTGAGTTGTCTCTATGTGTATTCAAT
CTCCCCTAGTGAAGTTCAATTCTGCACTTCAGTGTAAGCAGTGTTGACATTCAGTTCTCACCAC
TCTAACTATTCAACCTAATAAAGTGATTTTTAAAACTTGT

hide sequence

RefSeq Acc Id:

XM_063281753 ⟹ XP_063137823

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	84,291,120 - 84,301,878 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001008770	(Get FASTA)	NCBI Sequence Viewer
	XP_006232159	(Get FASTA)	NCBI Sequence Viewer
	XP_063137823	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88459	(Get FASTA)	NCBI Sequence Viewer
	AAP92598	(Get FASTA)	NCBI Sequence Viewer
	EDL82643	(Get FASTA)	NCBI Sequence Viewer
	EDL82644	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015448
	ENSRNOP00000015448.4
	ENSRNOP00000079112
GenBank Protein	Q7TP52	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001008770 ⟸ NM_001008770

- UniProtKB:

Q7TP52 (UniProtKB/Swiss-Prot), A6JMZ5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MANEANPCPCDIGHRLDYGGMGQEVQVEHIKAYVTRSPVDAGKAVIVVQDIFGWQLSNTRYMAD
MIAGNGYTTIVPDFFVGQEPWDPAGDWSTFPEWLKSRNARKINREVDAVLRYLKQQCHAQKIGI
VGFCWGGIVVHHVMTTYPEVRAGVSVYGIIRDSEDVYNLKNPTLFIFAENDAVIPLEQVSILIQ
KLKEHCIVNYQVKTFSGQTHGFVHRKREDCSPADKPYIEEARRNLIEWLNKYI

hide sequence

RefSeq Acc Id:	XP_006232159 ⟸ XM_006232097
- Peptide Label:	isoform X2
- UniProtKB:	Q7TP52 (UniProtKB/Swiss-Prot), A6JMZ5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MANEANPCPCDIGHRLDYGGMGQEVQVEHIKAYVTRSPVDAGKAVIVVQDIFGWQLSNTRYMAD MIAGNGYTTIVPDFFVGQEPWDPAGDWSTFPEWLKSRNARKINREVDAVLRYLKQQCHAQKIGI VGFCWGGIVVHHVMTTYPEVRAGVSVYGIIRDSEDVYNLKNPTLFIFAENDAVIPLEQVSILIQ KLKEHCIVNYQVKTFSGQTHGFVHRKREDCSPADKPYIEEARRNLIEWLNKYI hide sequence

Ensembl Acc Id:

ENSRNOP00000015448 ⟸ ENSRNOT00000015448

Ensembl Acc Id:

ENSRNOP00000079112 ⟸ ENSRNOT00000118086

RefSeq Acc Id:	XP_063137823 ⟸ XM_063281753
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMF1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000101821 ⟸ ENSRNOT00000145367

Protein Domains

Dienelactone hydrolase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TP52-F1-model_v2	AlphaFold	Q7TP52	1-245	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691211

Promoter ID:

EPDNEW_R1736

Type:

initiation region

Name:

Cmbl_1

Description:

carboxymethylenebutenolidase homolog

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	84,645,063 - 84,645,123	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306952	AgrOrtholog
BioCyc Gene	G2FUF-53861	BioCyc
Ensembl Genes	ENSRNOG00000011260	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000015448	ENTREZGENE
	ENSRNOT00000015448.8	UniProtKB/Swiss-Prot
	ENSRNOT00000118086	ENTREZGENE
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7127481	IMAGE-MGC_LOAD
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot
	CMBL	UniProtKB/Swiss-Prot
	Dienelactn_hydro	UniProtKB/Swiss-Prot
KEGG Report	rno:310201	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:95111	IMAGE-MGC_LOAD
NCBI Gene	310201	ENTREZGENE
PANTHER	CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG	UniProtKB/Swiss-Prot
	PTHR46812	UniProtKB/Swiss-Prot
Pfam	DLH	UniProtKB/Swiss-Prot
PhenoGen	Cmbl	PhenoGen
RatGTEx	ENSRNOG00000011260	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZMF1	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L0W7_RAT	UniProtKB/TrEMBL
	A6JMZ5	ENTREZGENE, UniProtKB/TrEMBL
	CMBL_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-29	Cmbl	carboxymethylenebutenolidase homolog	Cmbl	carboxymethylenebutenolidase homolog (Pseudomonas)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Cmbl	carboxymethylenebutenolidase homolog (Pseudomonas)	RGD1306952	similar to Ab2-225	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1306952	similar to Ab2-225	RGD1306952_predicted	similar to Ab2-225 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306952_predicted	similar to Ab2-225 (predicted)	LOC310201_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC310201_predicted	similar to Ab2-225 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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