Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fbxl5 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FBXL5 mRNA | CTD | PMID:22079256 | Fbxl5 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Fbxl5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FBXL5 mRNA | CTD | PMID:36331819 | Fbxl5 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Fbxl5 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of FBXL5 mRNA | CTD | PMID:22206623 | Fbxl5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FBXL5 mRNA | CTD | PMID:21570461 | Fbxl5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FBXL5 mRNA | CTD | PMID:33387578 | Fbxl5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FBXL5 mRNA | CTD | PMID:28213091 | Fbxl5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Fbxl5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to FBXL5 gene] | CTD | PMID:28213091 | Fbxl5 | Rat | aflatoxin B1 | decreases methylation | ISO | FBXL5 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FBXL5 gene | CTD | PMID:27153756 | Fbxl5 | Rat | all-trans-retinoic acid | increases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of FBXL5 mRNA | CTD | PMID:23724009|PMID:33167477 | Fbxl5 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of FBXL5 mRNA | CTD | PMID:30779732 | Fbxl5 | Rat | antirheumatic drug | increases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of FBXL5 mRNA | CTD | PMID:24449571 | Fbxl5 | Rat | Aroclor 1254 | decreases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of FBXL5 mRNA | CTD | PMID:23650126 | Fbxl5 | Rat | arsane | affects expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Arsenic affects the expression of FBXL5 mRNA | CTD | PMID:18414638 | Fbxl5 | Rat | arsane | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Fbxl5 | Rat | arsenic atom | affects expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Arsenic affects the expression of FBXL5 mRNA | CTD | PMID:18414638 | Fbxl5 | Rat | arsenic atom | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Fbxl5 | Rat | benzo[a]pyrene | increases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of FBXL5 mRNA | CTD | PMID:22228805 | Fbxl5 | Rat | benzo[a]pyrene | increases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FBXL5 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291 | Fbxl5 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FBXL5 mRNA | CTD | PMID:19150397 | Fbxl5 | Rat | beta-lapachone | increases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of FBXL5 mRNA | CTD | PMID:38218311 | Fbxl5 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FBXL5 mRNA | CTD | PMID:25181051 | Fbxl5 | Rat | butan-1-ol | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... | CTD | PMID:29432896 | Fbxl5 | Rat | cadmium atom | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of FBXL5 mRNA | CTD | PMID:24284285 | Fbxl5 | Rat | cadmium atom | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FBXL5 more ... | CTD | PMID:35301059 | Fbxl5 | Rat | cadmium dichloride | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FBXL5 more ... | CTD | PMID:35301059 | Fbxl5 | Rat | carbon nanotube | increases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of FBXL5 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Fbxl5 | Rat | CGP 52608 | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FBXL5 gene] | CTD | PMID:28238834 | Fbxl5 | Rat | chlorpyrifos | decreases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of FBXL5 mRNA | CTD | PMID:37019170 | Fbxl5 | Rat | chromium(6+) | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | chromium hexavalent ion results in decreased expression of FBXL5 mRNA | CTD | PMID:30690063 | Fbxl5 | Rat | cisplatin | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FBXL5 mRNA | CTD | PMID:27392435 | Fbxl5 | Rat | coumestrol | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of FBXL5 mRNA | CTD | PMID:19167446 | Fbxl5 | Rat | crocidolite asbestos | decreases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of FBXL5 mRNA | CTD | PMID:29279043 | Fbxl5 | Rat | Dibutyl phosphate | affects expression | ISO | FBXL5 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of FBXL5 mRNA | CTD | PMID:37042841 | Fbxl5 | Rat | dicrotophos | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of FBXL5 mRNA | CTD | PMID:28302478 | Fbxl5 | Rat | disodium selenite | increases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of FBXL5 mRNA | CTD | PMID:18175754 | Fbxl5 | Rat | elemental selenium | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Selenium results in decreased expression of FBXL5 mRNA | CTD | PMID:19244175 | Fbxl5 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of FBXL5 mRNA | CTD | PMID:24136188 | Fbxl5 | Rat | folic acid | decreases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of FBXL5 mRNA | CTD | PMID:25629700 | Fbxl5 | Rat | formaldehyde | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of FBXL5 mRNA | CTD | PMID:20655997 | Fbxl5 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of FBXL5 mRNA | CTD | PMID:22061828|PMID:33387578 | Fbxl5 | Rat | inulin | multiple interactions | ISO | Fbxl5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of FBXL5 mRNA | CTD | PMID:36331819 | Fbxl5 | Rat | manganese atom | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Fbxl5 | Rat | manganese(0) | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Fbxl5 | Rat | manganese(II) chloride | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Fbxl5 | Rat | paracetamol | affects expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Acetaminophen affects the expression of FBXL5 mRNA | CTD | PMID:17562736 | Fbxl5 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FBXL5 mRNA | CTD | PMID:33387578 | Fbxl5 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Fbxl5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FBXL5 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Fbxl5 | Rat | potassium chromate | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FBXL5 mRNA | CTD | PMID:22079256 | Fbxl5 | Rat | potassium chromate | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FBXL5 mRNA | CTD | PMID:22079256|PMID:22714537 | Fbxl5 | Rat | potassium dichromate | increases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of FBXL5 mRNA | CTD | PMID:23608068 | Fbxl5 | Rat | rimonabant | multiple interactions | ISO | Fbxl5 (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FBXL5 mRNA] | CTD | PMID:19030233 | Fbxl5 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of FBXL5 mRNA | CTD | PMID:19013527 | Fbxl5 | Rat | selenium atom | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Selenium results in decreased expression of FBXL5 mRNA | CTD | PMID:19244175 | Fbxl5 | Rat | silicon dioxide | increases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of FBXL5 mRNA | CTD | PMID:25351596 | Fbxl5 | Rat | sodium arsenate | decreases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of FBXL5 mRNA | CTD | PMID:39847705 | Fbxl5 | Rat | sodium arsenite | increases stability | ISO | FBXL5 (Homo sapiens) | 6480464 | sodium arsenite results in increased stability of FBXL5 mRNA | CTD | PMID:25493608 | Fbxl5 | Rat | sodium arsenite | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of FBXL5 mRNA | CTD | PMID:39719251 | Fbxl5 | Rat | sodium arsenite | multiple interactions | ISO | FBXL5 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Fbxl5 | Rat | sodium arsenite | affects expression | ISO | FBXL5 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of FBXL5 mRNA | CTD | PMID:29319823 | Fbxl5 | Rat | sunitinib | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of FBXL5 mRNA | CTD | PMID:31533062 | Fbxl5 | Rat | titanium dioxide | increases methylation | ISO | Fbxl5 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of FBXL5 gene | CTD | PMID:35295148 | Fbxl5 | Rat | tremolite asbestos | increases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | tremolite results in increased expression of FBXL5 mRNA | CTD | PMID:29279043 | Fbxl5 | Rat | triphenyl phosphate | affects expression | ISO | FBXL5 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FBXL5 mRNA | CTD | PMID:37042841 | Fbxl5 | Rat | triptonide | decreases expression | ISO | Fbxl5 (Mus musculus) | 6480464 | triptonide results in decreased expression of FBXL5 mRNA | CTD | PMID:33045310 | Fbxl5 | Rat | valproic acid | decreases methylation | ISO | FBXL5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of FBXL5 gene | CTD | PMID:29154799 | Fbxl5 | Rat | valproic acid | decreases expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FBXL5 mRNA | CTD | PMID:23179753 | Fbxl5 | Rat | valproic acid | affects expression | ISO | FBXL5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FBXL5 mRNA | CTD | PMID:25979313 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















