Ints11 (integrator complex subunit 11) - Rat Genome Database

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Pathways
Gene: Ints11 (integrator complex subunit 11) Rattus norvegicus
Analyze
Symbol: Ints11
Name: integrator complex subunit 11
RGD ID: 1306841
Description: Predicted to enable RNA endonuclease activity. Predicted to be involved in RNA polymerase II transcription initiation surveillance and snRNA 3'-end processing. Predicted to act upstream of or within transcription elongation by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of INTAC complex and integrator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with motor and language delay, ocular defects, and brain abnormalities. Orthologous to human INTS11 (integrator complex subunit 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cleavage and polyadenylation specific factor 3-like; cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Cpsf3l; int11; LOC298688; MGC124975; RGD1306841; similar to RIKEN cDNA 2410006F12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,761,370 - 171,779,883 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5171,761,371 - 171,779,883 (+)EnsemblGRCr8
mRatBN7.25166,479,134 - 166,497,956 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,479,155 - 166,497,651 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5169,183,861 - 169,202,461 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,005,282 - 171,023,882 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,967,813 - 170,986,414 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,318,435 - 173,336,930 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,318,479 - 173,336,930 (+)Ensemblrn6Rnor6.0
Rnor_5.05176,794,059 - 176,812,548 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45172,728,160 - 172,746,611 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5164,679,889 - 164,698,375 (+)NCBICelera
RGSC_v3.15172,738,640 - 172,757,106 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO,ISS)
cytosol  (IEA,ISO)
INTAC complex  (IEA,ISO,ISS)
integrator complex  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:16239144   PMID:22516433   PMID:23904267  


Genomics

Comparative Map Data
Ints11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,761,370 - 171,779,883 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5171,761,371 - 171,779,883 (+)EnsemblGRCr8
mRatBN7.25166,479,134 - 166,497,956 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,479,155 - 166,497,651 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5169,183,861 - 169,202,461 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,005,282 - 171,023,882 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,967,813 - 170,986,414 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,318,435 - 173,336,930 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,318,479 - 173,336,930 (+)Ensemblrn6Rnor6.0
Rnor_5.05176,794,059 - 176,812,548 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45172,728,160 - 172,746,611 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5164,679,889 - 164,698,375 (+)NCBICelera
RGSC_v3.15172,738,640 - 172,757,106 (+)NCBI
Cytogenetic Map5q36NCBI
INTS11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,311,600 - 1,324,660 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,311,585 - 1,324,687 (-)Ensemblhg38GRCh38
GRCh3711,246,980 - 1,260,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,236,828 - 1,249,909 (-)NCBIBuild 36Build 36hg18NCBI36
Celera11,321,096 - 1,334,176 (+)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1518,567 - 531,272 (-)NCBIHuRef
CHM1_111,233,996 - 1,247,095 (-)NCBICHM1_1
T2T-CHM13v2.01743,151 - 756,245 (-)NCBIT2T-CHM13v2.0
Ints11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,954,006 - 155,973,561 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,954,003 - 155,973,560 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384155,869,547 - 155,889,103 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,869,546 - 155,889,103 (+)Ensemblmm10GRCm38
MGSCv374155,243,676 - 155,263,212 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364154,713,367 - 154,732,903 (+)NCBIMGSCv36mm8
Celera4158,140,490 - 158,160,072 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.66NCBI
Ints11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,479,057 - 9,491,629 (+)Ensembl
ChiLan1.0NW_0049554869,479,057 - 9,491,629 (+)NCBIChiLan1.0ChiLan1.0
INTS11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,899,932 - 226,915,600 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,598,471 - 225,612,288 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0166,280 - 81,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,266,581 - 1,281,430 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,266,581 - 1,281,430 (-)EnsemblpanPan2panpan1.1
INTS11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,485,690 - 56,498,074 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,485,948 - 56,498,017 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha556,562,020 - 56,574,377 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0556,687,937 - 56,700,267 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,687,937 - 56,700,243 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,678,657 - 56,691,014 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,570,943 - 56,583,298 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,960,955 - 56,973,519 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ints11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,632,649 - 27,645,493 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367371,822,826 - 1,833,104 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367371,820,472 - 1,833,301 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INTS11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,596,803 - 63,607,921 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1663,596,809 - 63,607,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,094,883 - 58,105,971 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INTS11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,128,828 - 130,139,580 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,128,828 - 130,142,330 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605434,692,148 - 34,705,942 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ints11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,289,929 - 8,299,254 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248188,287,539 - 8,299,456 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ints11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v114,741,981 - 4,760,119 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:89
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000026725
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat

Markers in Region
RH130347  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85171,779,378 - 171,779,626 (+)Marker Load Pipeline
mRatBN7.25166,497,146 - 166,497,394 (+)MAPPERmRatBN7.2
Rnor_6.05173,336,426 - 173,336,673NCBIRnor6.0
Rnor_5.05176,812,044 - 176,812,291UniSTSRnor5.0
RGSC_v3.45172,746,107 - 172,746,354UniSTSRGSC3.4
Celera5164,697,871 - 164,698,118UniSTS
RH 3.4 Map51173.8UniSTS
Cytogenetic Map5q36UniSTS
RH143513  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,497,662 - 166,497,785 (+)MAPPERmRatBN7.2
Rnor_6.05173,336,942 - 173,337,064NCBIRnor6.0
Rnor_5.05176,812,560 - 176,812,682UniSTSRnor5.0
RGSC_v3.45172,746,623 - 172,746,745UniSTSRGSC3.4
Celera5164,698,387 - 164,698,509UniSTS
RH 3.4 Map51173.8UniSTS
Cytogenetic Map5q36UniSTS
RH138955  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,497,812 - 166,497,946 (+)MAPPERmRatBN7.2
Rnor_6.05173,337,092 - 173,337,225NCBIRnor6.0
Rnor_5.05176,812,710 - 176,812,843UniSTSRnor5.0
RGSC_v3.45172,746,773 - 172,746,906UniSTSRGSC3.4
Celera5164,698,537 - 164,698,670UniSTS
RH 3.4 Map51174.7UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026725   ⟹   ENSRNOP00000026725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5171,761,400 - 171,779,883 (+)Ensembl
mRatBN7.2 Ensembl5166,479,155 - 166,497,651 (+)Ensembl
Rnor_6.0 Ensembl5173,318,479 - 173,336,930 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101518   ⟹   ENSRNOP00000087757
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5171,761,371 - 171,779,881 (+)Ensembl
mRatBN7.2 Ensembl5166,479,155 - 166,497,651 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107036   ⟹   ENSRNOP00000095330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5171,763,042 - 171,779,883 (+)Ensembl
mRatBN7.2 Ensembl5166,480,808 - 166,497,651 (+)Ensembl
RefSeq Acc Id: NM_001033892   ⟹   NP_001029064
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,405 - 171,779,883 (+)NCBI
mRatBN7.25166,479,171 - 166,497,651 (+)NCBI
Rnor_6.05173,318,452 - 173,336,930 (+)NCBI
Rnor_5.05176,794,059 - 176,812,548 (+)NCBI
RGSC_v3.45172,728,160 - 172,746,611 (+)RGD
Celera5164,679,889 - 164,698,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239549   ⟹   XP_006239611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,370 - 171,779,883 (+)NCBI
mRatBN7.25166,479,137 - 166,497,956 (+)NCBI
Rnor_6.05173,318,436 - 173,336,930 (+)NCBI
Rnor_5.05176,794,059 - 176,812,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239550   ⟹   XP_006239612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,370 - 171,779,883 (+)NCBI
mRatBN7.25166,479,138 - 166,497,651 (+)NCBI
Rnor_6.05173,318,436 - 173,336,930 (+)NCBI
Rnor_5.05176,794,059 - 176,812,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239551   ⟹   XP_006239613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,370 - 171,779,883 (+)NCBI
mRatBN7.25166,479,138 - 166,497,956 (+)NCBI
Rnor_6.05173,318,437 - 173,336,930 (+)NCBI
Rnor_5.05176,794,059 - 176,812,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239552   ⟹   XP_006239614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,561 - 171,779,883 (+)NCBI
mRatBN7.25166,479,317 - 166,497,956 (+)NCBI
Rnor_6.05173,318,596 - 173,336,930 (+)NCBI
Rnor_5.05176,794,059 - 176,812,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239553   ⟹   XP_006239615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,371 - 171,779,883 (+)NCBI
mRatBN7.25166,479,134 - 166,497,956 (+)NCBI
Rnor_6.05173,318,435 - 173,336,930 (+)NCBI
Rnor_5.05176,794,059 - 176,812,548 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593318   ⟹   XP_017448807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,763,693 - 171,779,883 (+)NCBI
mRatBN7.25166,481,460 - 166,497,956 (+)NCBI
Rnor_6.05173,321,256 - 173,336,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063287506   ⟹   XP_063143576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,761,567 - 171,779,883 (+)NCBI
RefSeq Acc Id: NP_001029064   ⟸   NM_001033892
- UniProtKB: A0A8L2UK86 (UniProtKB/TrEMBL),   A6IUT8 (UniProtKB/TrEMBL),   A0A8I6B2F1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239611   ⟸   XM_006239549
- Peptide Label: isoform X1
- UniProtKB: A0A8I6B2F1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239612   ⟸   XM_006239550
- Peptide Label: isoform X2
- UniProtKB: A0A8I6B2F1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239613   ⟸   XM_006239551
- Peptide Label: isoform X3
- UniProtKB: A0A8I6B2F1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239615   ⟸   XM_006239553
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A6F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239614   ⟸   XM_006239552
- Peptide Label: isoform X4
- UniProtKB: A0A8I6B2F1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448807   ⟸   XM_017593318
- Peptide Label: isoform X7
- Sequence:
Ensembl Acc Id: ENSRNOP00000026725   ⟸   ENSRNOT00000026725
Ensembl Acc Id: ENSRNOP00000095330   ⟸   ENSRNOT00000107036
Ensembl Acc Id: ENSRNOP00000087757   ⟸   ENSRNOT00000101518
RefSeq Acc Id: XP_063143576   ⟸   XM_063287506
- Peptide Label: isoform X6
- UniProtKB: A0A8I6B2F1 (UniProtKB/TrEMBL)
Protein Domains
Beta-Casp   Metallo-beta-lactamase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3MHC2-F1-model_v2 AlphaFold Q3MHC2 1-600 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694335
Promoter ID:EPDNEW_R4860
Type:initiation region
Name:Ints11_1
Description:integrator complex subunit 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,318,438 - 173,318,498EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306841 AgrOrtholog
BioCyc Gene G2FUF-38890 BioCyc
Ensembl Genes ENSRNOG00000019712 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000026725 ENTREZGENE
  ENSRNOT00000101518 ENTREZGENE
  ENSRNOT00000107036 ENTREZGENE
Gene3D-CATH 3.40.50.10890 UniProtKB/Swiss-Prot
  3.60.15.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110348 IMAGE-MGC_LOAD
InterPro Beta_Casp UniProtKB/Swiss-Prot
  INTS11-like_MBL-fold UniProtKB/Swiss-Prot
  IntS11_C UniProtKB/Swiss-Prot
  Metallo-B-lactamas UniProtKB/Swiss-Prot
  RibonucZ/Hydroxyglut_hydro UniProtKB/Swiss-Prot
  RMMBL UniProtKB/Swiss-Prot
  RNA_Proc_MBL-domain UniProtKB/Swiss-Prot
KEGG Report rno:298688 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124975 IMAGE-MGC_LOAD
NCBI Gene 298688 ENTREZGENE
PANTHER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER UniProtKB/Swiss-Prot
  INTEGRATOR COMPLEX SUBUNIT 11 UniProtKB/Swiss-Prot
Pfam Beta-Casp UniProtKB/Swiss-Prot
  IntS11_C UniProtKB/Swiss-Prot
  Lactamase_B_6 UniProtKB/Swiss-Prot
  RMMBL UniProtKB/Swiss-Prot
PhenoGen Ints11 PhenoGen
RatGTEx ENSRNOG00000019712 RatGTEx
SMART Beta-Casp UniProtKB/Swiss-Prot
  Lactamase_B UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56281 UniProtKB/Swiss-Prot
UniProt A0A8I6A6F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B2F1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UK86 ENTREZGENE, UniProtKB/TrEMBL
  A6IUT8 ENTREZGENE, UniProtKB/TrEMBL
  INT11_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-03 Ints11  integrator complex subunit 11  Cpsf3l  cleavage and polyadenylation specific factor 3-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Cpsf3l  cleavage and polyadenylation specific factor 3-like  RGD1306841  similar to RIKEN cDNA 2410006F12  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1306841  similar to RIKEN cDNA 2410006F12  RGD1306841_predicted  similar to RIKEN cDNA 2410006F12 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1306841_predicted  similar to RIKEN cDNA 2410006F12 (predicted)  LOC298688_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC298688_predicted  similar to RIKEN cDNA 2410006F12 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL