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Gene: Rnf217 (ring finger protein 217) Rattus norvegicus

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Symbol:

Rnf217

Name:

ring finger protein 217

RGD ID:

1306836

Description:

Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human RNF217 (ring finger protein 217); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; atrazine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

E3 ubiquitin-protein ligase RNF217; IBR domain containing 1; Ibrdc1; LOC292188; probable E3 ubiquitin-protein ligase RNF217

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF217 (ring finger protein 217)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Rnf217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rnf217 (ring finger protein 217)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RNF217 (ring finger protein 217)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnf217 (ring finger protein 217)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnf217 (ring finger protein 217)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rnf217	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rnf217	Alliance	DIOPT (OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	27,835,741 - 27,927,805 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	27,835,148 - 27,928,044 (+)	Ensembl				GRCr8
mRatBN7.2	1	26,016,668 - 26,108,736 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	26,015,728 - 26,108,736 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	25,764,307 - 25,856,182 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	31,764,134 - 31,856,009 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	25,964,885 - 26,056,790 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	28,301,960 - 28,391,582 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	28,301,922 - 28,390,837 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	29,676,521 - 29,846,859 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	26,630,933 - 26,723,874 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	24,711,297 - 24,803,602 (+)	NCBI		Celera
RGSC_v3.1	1	26,556,135 - 26,727,060 (+)	NCBI
Cytogenetic Map	1	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

multiple sclerosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aristolochic acid A (ISO)

atrazine (EXP)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

epoxiconazole (ISO)

fluoranthene (ISO)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

leflunomide (EXP)

mercury dibromide (ISO)

methylmercury chloride (ISO)

nickel dichloride (EXP)

okadaic acid (ISO)

panobinostat (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein ubiquitination (IEA)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

cytoplasm (IBA,IEA)

membrane (IEA)

ubiquitin ligase complex (IBA)

Molecular Function

metal ion binding (IEA)

transferase activity (IEA)

ubiquitin conjugating enzyme binding (IBA)

ubiquitin protein ligase activity (IBA,IEA)

ubiquitin-protein transferase activity (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19028597

Genomics

Comparative Map Data

Rnf217
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	27,835,741 - 27,927,805 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	27,835,148 - 27,928,044 (+)	Ensembl				GRCr8
mRatBN7.2	1	26,016,668 - 26,108,736 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	26,015,728 - 26,108,736 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	25,764,307 - 25,856,182 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	31,764,134 - 31,856,009 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	25,964,885 - 26,056,790 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	28,301,960 - 28,391,582 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	28,301,922 - 28,390,837 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	29,676,521 - 29,846,859 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	26,630,933 - 26,723,874 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	24,711,297 - 24,803,602 (+)	NCBI		Celera
RGSC_v3.1	1	26,556,135 - 26,727,060 (+)	NCBI
Cytogenetic Map	1	p11	NCBI

RNF217
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	124,962,437 - 125,092,634 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	124,962,437 - 125,092,633 (+)	Ensembl			hg38	GRCh38
GRCh37	6	125,283,583 - 125,413,780 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	125,346,213 - 125,446,360 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	125,346,212 - 125,446,359	NCBI
Celera	6	126,049,522 - 126,149,701 (+)	NCBI		Celera
Cytogenetic Map	6	q22.31	NCBI
HuRef	6	122,881,176 - 122,981,254 (+)	NCBI		HuRef
CHM1_1	6	125,567,969 - 125,668,114 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	126,150,465 - 126,280,671 (+)	NCBI		T2T-CHM13v2.0

Rnf217
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	31,377,883 - 31,485,721 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	31,369,189 - 31,485,180 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	31,501,887 - 31,609,725 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	31,493,193 - 31,609,184 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	31,221,693 - 31,329,531 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	31,191,301 - 31,300,328 (-)	NCBI		MGSCv36	mm8
Celera	10	32,427,225 - 32,533,457 (-)	NCBI		Celera
Cytogenetic Map	10	A4	NCBI
cM Map	10	17.45	NCBI

Rnf217
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	6,456,987 - 6,561,509 (+)	Ensembl
ChiLan1.0	NW_004955436	6,458,088 - 6,566,112 (+)	NCBI	ChiLan1.0	ChiLan1.0

RNF217
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	144,952,595 - 145,081,827 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	142,856,546 - 142,985,343 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	122,747,128 - 122,875,930 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	126,878,597 - 127,001,757 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	126,867,604 - 126,992,867 (+)	Ensembl			panPan2	panpan1.1

RNF217
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	63,902,985 - 64,094,491 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	63,962,515 - 64,085,011 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	64,771,771 - 64,904,604 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	64,169,156 - 64,302,061 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	64,168,719 - 64,294,050 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	64,100,868 - 64,233,594 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	63,830,960 - 64,020,201 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	64,538,810 - 64,671,819 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rnf217
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	114,090,629 - 114,132,623 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936639	4,295,293 - 4,325,468 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF217
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	37,788,472 - 37,912,122 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	37,784,359 - 37,912,122 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	41,674,373 - 41,734,266 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF217
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	48,612,687 - 48,743,821 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	20,922,993 - 21,056,572 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf217
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624798	6,390,200 - 6,499,471 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rnf217
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	205,603,681 - 205,701,348 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rnf217
592 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	102
Count of miRNA genes:	81
Interacting mature miRNAs:	101
Transcripts:	ENSRNOT00000017831
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	5293229	34184556	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	7746118	52746118	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	7746121	52746121	Rat
70179	Xhs2	X-ray hypersensitivity QTL 2	3.2		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	1	1	43965634	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	10379492	55379492	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	6941022	51941022	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	5293229	34184556	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	6909353	51909353	Rat
631494	Bp95	Blood pressure QTL 95	40	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	17315378	51816258	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	6909353	51909353	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	6909353	51909353	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	12820494	57820494	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	1	34184556	Rat
634353	Rends2	Renal damage susceptibility QTL 2		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	1	20656420	65656420	Rat
1300170	Rf6	Renal function QTL 6	3.14		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	1	1	28483164	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	20508326	65508326	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	11684464	56684464	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	5293229	34184556	Rat

Markers in Region

AU048645

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	26,032,086 - 26,032,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	28,317,379 - 28,317,498	NCBI	Rnor6.0
Rnor_5.0	1	29,772,653 - 29,772,772	UniSTS	Rnor5.0
RGSC_v3.4	1	26,646,352 - 26,646,471	UniSTS	RGSC3.4
Celera	1	24,726,699 - 24,726,818	UniSTS
Cytogenetic Map	1	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
21	13	79	211	91	90	59	139	59	6	452	261	22	189	103	119	31	34	34

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017831 ⟹ ENSRNOP00000017831

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	27,835,148 - 27,928,044 (+)	Ensembl
mRatBN7.2 Ensembl	1	26,015,728 - 26,108,736 (+)	Ensembl
Rnor_6.0 Ensembl	1	28,301,922 - 28,390,837 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000138658 ⟹ ENSRNOP00000108903

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	27,835,148 - 27,927,115 (+)	Ensembl

RefSeq Acc Id:

NM_001106204 ⟹ NP_001099674

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	27,835,741 - 27,927,805 (+)	NCBI
mRatBN7.2	1	26,016,668 - 26,108,736 (+)	NCBI
Rnor_6.0	1	28,301,960 - 28,391,582 (+)	NCBI
Rnor_5.0	1	29,676,521 - 29,846,859 (+)	NCBI
RGSC_v3.4	1	26,630,933 - 26,723,874 (+)	RGD
Celera	1	24,711,297 - 24,803,602 (+)	RGD

Sequence:

show sequence

ACCCGCCCCCCGCCAAGCCGCAAGTCCTCTGCTCTGTGTACTGCGTGGAGAGCGACCTGCCCGA
GGCCCCCTCCGCCGAGTCCCCGTCGCCTCCGGAGTCCCCACCTCAAGCACCGCCGGGGCCGATT
CCCGCCAGTCCGCCTGCCTCCTTTCCAAGCTCCCCGCTGTCGCTCCCGGCTGACCCCCTATCCC
CCGACGGCGGCAGCATCGAGCTGGAGTTCTACCTGGCTCCGGAGCCCTTCTCCGTGCCTGGCCT
ATTAGGAGCTCCACCCTACTCTGGCCTGGGCGGGGTAGGGGACCCCTATGCGCCCCTCATGGTG
CTGATGTGCCGGGTGTGCCTGGAAGACAAGCCCATCAAGCCCCTGCCCTGCTGCAAGAAGGCGG
TGTGCGAGGAGTGCCTCAAAATCTACCTGAGCTCTCAGGTACAACTTGGCCAAGTAGAAATCAA
ATGCCCAGTCACAGAGTGTTTCGAGTTCCTGGAGGAAACAACTGTTGTCTACAACTTAACCCAT
GAGGACTCCATCAAGTATAAGTACTTCTTGGAACTTGGCCGGATTGACTCCAGCACCAAGCCGT
GTCCTCAATGCAAACACTTCACAACCTTTAAGAAAAAAGGACATATCCCCACTCCTTCCAGATC
AGAAAGCAGATACAAAATCCAGTGTCCCACTTGCCAATTCATCTGGTGTTTTAAGTGCCACTCT
CCTTGGCATGAAGGTGTTAACTGCAAGGAGTACAGAAAAGGAGACAAGTTATTGCGTCACTGGG
CCAGTGAGATTGAGCACGGGCAGAGAAATGCCCAGAAGTGTCCAAAGTGCAAGATCCATATCCA
GAGGACAGAAGGGTGTGACCATATGACTTGTTCACAGTGTAACACTAATTTTTGCTATCGATGT
GGAGAGAGATACCGCCAGCTCCGGTTTTTCGGAGACCATACATCAAACCTCAGTATATTTGGAT
GCAAATATCGCTACCTCCCAGAGAGACCTCACTTAAGAAGATTAGTTCGAGGGTCAGTCTGTGC
TGGAAAGCTCTTCATTGCGCCTCTTATCCTGGTTTTGGGATTGGCACTAGGGGCCATAGCAGTT
GTAATTGGTTTATTTGTATTTCCTATATATTGCCTTTGTAAAAAACAGAGAAAGCGATCACGGA
CAGGTATGCACTGGTAATCCACAGAGGACTTCACATGACGTCAGCTGGTACCAGGAGGAGCCGT
GCAGGGTTGTGCACCTGTCTGTGAGTTGGATCCTTCAAACCACCAAGAGGAACCTGTGCCATCT
CGTGTCCTGTGGTTCTCTGCAGGCCACAGTGCTCTAGCTACGGTGCACTCCCATGGTATCCTGT
CCTTTCCCTAAACAATTGCTGCTCTGAAAAATGAAACGGTCACTTTCGTTAACTATAGACATTT
ACATAGTAACTCTGGCCTTTGTGGCTCTCGGAAGAAAATACTTTGAGAACAGGGTATCCTCAGA
TGTGTTTTGAGGACACCTCACAGGAGTGTTATTTGGATTGTCTGAACCTTGTGCTTCCCCAGGC
TGTCTCTGAGACTTGGTATGCATAGCTGAATCCTGCCCGTCTCAACAAACAAAGCCACTTTTCA
GAAGATAAATCAAAGTTCATCAAATGCACCTGTTGTCATCTGTAACCCAAATGGTATAGTCATT
TTGTTCTTTGGATACTGTAATTGCTTTAAAAAAAAATCTCAGCACCCAGAAGGGAATTAATGAA
ACTAAATTAATGAGAAGAACCTGAGTTCCTGGTGCGTGTATGTAAGGATGTGAATGTGTGTATA
TAAACACGTATTAAACCAGGCTCCGTAACCGTGTGCTCGTCCATTTCCGTGTCTGTTCTCATAC
AGCCTTTCAGCCATGATGGTTATTTCCGTGGGCCTAACTTGGTAATGTACTGAATTAAAGCCAG
TGTCAACAAC

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Protein Sequences


Protein RefSeqs	NP_001099674	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL87714	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017831.6
	ENSRNOP00000108903.1

RefSeq Acc Id:

NP_001099674 ⟸ NM_001106204

- UniProtKB:

A6JUR5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVLMCRVCLEDKPIKPLPCCKKAVCEECLKIYLSSQVQLGQVEIKCPVTECFEFLEETTVVYNL
THEDSIKYKYFLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESRYKIQCPTCQFIWCFKC
HSPWHEGVNCKEYRKGDKLLRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCY
RCGERYRQLRFFGDHTSNLSIFGCKYRYLPERPHLRRLVRGSVCAGKLFIAPLILVLGLALGAI
AVVIGLFVFPIYCLCKKQRKRSRTGMHW

hide sequence

Ensembl Acc Id:

ENSRNOP00000017831 ⟸ ENSRNOT00000017831

Ensembl Acc Id:

ENSRNOP00000108903 ⟸ ENSRNOT00000138658

Protein Domains

RING-type

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306836	AgrOrtholog
BioCyc Gene	G2FUF-61988	BioCyc
Ensembl Genes	ENSRNOG00000013323	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000017831.7	UniProtKB/TrEMBL
	ENSRNOT00000138658.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.1750	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
InterPro	BRcat_RBR_RNF217	UniProtKB/TrEMBL
	E3_UB_ligase_RBR	UniProtKB/TrEMBL
	IBR_dom	UniProtKB/TrEMBL
	Rcat_RBR_RNF217	UniProtKB/TrEMBL
	RNF217_RBR_vRING-HC	UniProtKB/TrEMBL
	TRIAD_supradom	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
KEGG Report	rno:292188	UniProtKB/TrEMBL
NCBI Gene	292188	ENTREZGENE
PANTHER	PTHR11685	UniProtKB/TrEMBL
Pfam	IBR	UniProtKB/TrEMBL
	IBR_1	UniProtKB/TrEMBL
PhenoGen	Rnf217	PhenoGen
PROSITE	TRIAD	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013323	RatGTEx
SMART	IBR	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A0ABK0LXI5_RAT	UniProtKB/TrEMBL
	A6JUR5	ENTREZGENE, UniProtKB/TrEMBL
	D4ABK2_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Rnf217	ring finger protein 217	Ibrdc1_predicted	IBR domain containing 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Ibrdc1_predicted	IBR domain containing 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar