Gene: Agbl2 (AGBL carboxypeptidase 2) Rattus norvegicus
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Symbol:
Agbl2
Name:
AGBL carboxypeptidase 2
RGD ID:
1306827
Description:
Predicted to enable metallocarboxypeptidase activity and tubulin binding activity. Predicted to be involved in proteolysis. Predicted to be located in ciliary basal body and cytosol. Predicted to be active in centriole and cytoplasm. Orthologous to human AGBL2 (AGBL carboxypeptidase 2); INTERACTS WITH alpha-Zearalanol; bisphenol A; endosulfan.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
ATP/GTP binding protein-like 2; cytosolic carboxypeptidase 2; cytosolic carboxypeptidase 2-like; LOC103690183; LOC366124; RGD1306827; similar to CG32627-PB
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 97,220,654 - 97,255,905 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 3 97,220,781 - 97,255,904 (+) Ensembl GRCr8 mRatBN7.2 3 76,764,893 - 76,800,071 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 76,764,238 - 76,800,214 (+) Ensembl mRatBN7.2 Rnor_6.0 3 79,622,791 - 79,647,402 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 79,613,171 - 79,646,698 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 3 86,319,497 - 86,354,972 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 3 75,144,314 - 75,178,964 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 3 75,973,609 - 76,009,281 (+) NCBI Celera RGSC_v3.1 3 75,041,014 - 75,074,718 (+) NCBI Cytogenetic Map 3 q24 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Agbl2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Agbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Agbl2 Rat 1,2-dichloroethane increases expression ISO Agbl2 (Mus musculus) 6480464 ethylene dichloride results in increased expression of AGBL2 mRNA CTD PMID:28960355 Agbl2 Rat 1,2-dimethylhydrazine decreases expression ISO Agbl2 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of AGBL2 mRNA CTD PMID:22206623 Agbl2 Rat 17beta-estradiol multiple interactions ISO AGBL2 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of AGBL2 mRNA CTD PMID:30165855 Agbl2 Rat 17beta-estradiol decreases expression ISO AGBL2 (Homo sapiens) 6480464 Estradiol results in decreased expression of AGBL2 mRNA CTD PMID:31614463 Agbl2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Agbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Agbl2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Agbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Agbl2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Agbl2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of AGBL2 mRNA CTD PMID:21570461 Agbl2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Agbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Agbl2 Rat 4,4'-sulfonyldiphenol decreases expression ISO AGBL2 (Homo sapiens) 6480464 bisphenol S results in decreased expression of AGBL2 mRNA CTD PMID:30616060 Agbl2 Rat 4,4'-sulfonyldiphenol affects methylation ISO Agbl2 (Mus musculus) 6480464 bisphenol S affects the methylation of AGBL2 gene CTD PMID:31683443 Agbl2 Rat 4,4'-sulfonyldiphenol increases expression ISO Agbl2 (Mus musculus) 6480464 bisphenol S results in increased expression of AGBL2 mRNA CTD PMID:30951980 Agbl2 Rat aflatoxin B1 decreases expression ISO AGBL2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of AGBL2 mRNA CTD PMID:22100608 Agbl2 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of AGBL2 mRNA CTD PMID:35163327 Agbl2 Rat aristolochic acid A increases expression ISO AGBL2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of AGBL2 mRNA CTD PMID:33212167 Agbl2 Rat benzo[a]pyrene increases expression ISO Agbl2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of AGBL2 mRNA CTD PMID:27195522 Agbl2 Rat benzo[a]pyrene affects methylation ISO AGBL2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of AGBL2 exon CTD PMID:27901495 Agbl2 Rat benzo[a]pyrene decreases methylation ISO AGBL2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of AGBL2 promoter CTD PMID:27901495 Agbl2 Rat benzo[a]pyrene decreases methylation ISO Agbl2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of AGBL2 exon; Benzo(a)pyrene results in decreased methylation of AGBL2 more ... CTD PMID:27901495 Agbl2 Rat benzo[a]pyrene multiple interactions ISO Agbl2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Agbl2 Rat benzo[b]fluoranthene multiple interactions ISO Agbl2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Agbl2 Rat beta-lapachone decreases expression ISO AGBL2 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of AGBL2 mRNA CTD PMID:38218311 Agbl2 Rat bis(2-ethylhexyl) phthalate increases expression ISO Agbl2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of AGBL2 mRNA CTD PMID:34319233 Agbl2 Rat bisphenol A decreases expression ISO Agbl2 (Mus musculus) 6480464 bisphenol A results in decreased expression of AGBL2 mRNA CTD PMID:26063408 Agbl2 Rat bisphenol A increases expression ISO Agbl2 (Mus musculus) 6480464 bisphenol A results in increased expression of AGBL2 mRNA CTD PMID:30951980 Agbl2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AGBL2 mRNA CTD PMID:25181051 Agbl2 Rat bisphenol F increases expression ISO Agbl2 (Mus musculus) 6480464 bisphenol F results in increased expression of AGBL2 mRNA CTD PMID:30951980 Agbl2 Rat butanal decreases expression ISO AGBL2 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of AGBL2 mRNA CTD PMID:26079696 Agbl2 Rat caffeine decreases phosphorylation ISO AGBL2 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of AGBL2 protein CTD PMID:35688186 Agbl2 Rat carbon nanotube decreases expression ISO Agbl2 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of AGBL2 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Agbl2 Rat chrysene multiple interactions ISO Agbl2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Agbl2 Rat cisplatin increases expression ISO AGBL2 (Homo sapiens) 6480464 Cisplatin results in increased expression of AGBL2 mRNA CTD PMID:27392435 Agbl2 Rat crocidolite asbestos decreases expression ISO Agbl2 (Mus musculus) 6480464 Asbestos, Crocidolite results in decreased expression of AGBL2 mRNA CTD PMID:29279043 Agbl2 Rat cyclosporin A decreases expression ISO AGBL2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of AGBL2 mRNA CTD PMID:20106945 Agbl2 Rat dorsomorphin multiple interactions ISO AGBL2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Agbl2 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of AGBL2 mRNA CTD PMID:29391264 Agbl2 Rat epoxiconazole increases expression ISO Agbl2 (Mus musculus) 6480464 epoxiconazole results in increased expression of AGBL2 mRNA CTD PMID:35436446 Agbl2 Rat FR900359 increases phosphorylation ISO AGBL2 (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of AGBL2 protein CTD PMID:37730182 Agbl2 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of AGBL2 gene CTD PMID:35440735 Agbl2 Rat methylmercury chloride decreases expression ISO AGBL2 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of AGBL2 mRNA CTD PMID:28001369 Agbl2 Rat okadaic acid decreases expression ISO AGBL2 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of AGBL2 mRNA CTD PMID:38832940 Agbl2 Rat ozone multiple interactions ISO Agbl2 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... CTD PMID:34911549 Agbl2 Rat paracetamol increases expression ISO AGBL2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of AGBL2 mRNA CTD PMID:22230336 Agbl2 Rat paracetamol decreases expression ISO AGBL2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of AGBL2 mRNA CTD PMID:29067470 Agbl2 Rat PCB138 multiple interactions ISO Agbl2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Agbl2 Rat perfluorooctane-1-sulfonic acid decreases expression ISO AGBL2 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of AGBL2 mRNA CTD PMID:27153767 Agbl2 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of AGBL2 mRNA CTD PMID:35163327 Agbl2 Rat phenylmercury acetate decreases expression ISO AGBL2 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of AGBL2 mRNA CTD PMID:26272509 Agbl2 Rat phenylmercury acetate multiple interactions ISO AGBL2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Agbl2 Rat potassium dichromate decreases expression ISO Agbl2 (Mus musculus) 6480464 Potassium Dichromate results in decreased expression of AGBL2 mRNA CTD PMID:23608068 Agbl2 Rat quercetin increases expression ISO AGBL2 (Homo sapiens) 6480464 Quercetin results in increased expression of AGBL2 mRNA CTD PMID:21632981 Agbl2 Rat SB 431542 multiple interactions ISO AGBL2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Agbl2 Rat sodium arsenite decreases expression ISO AGBL2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of AGBL2 mRNA CTD PMID:29301061 Agbl2 Rat testosterone decreases expression ISO AGBL2 (Homo sapiens) 6480464 Testosterone results in decreased expression of AGBL2 mRNA CTD PMID:33359661 Agbl2 Rat tetraphene increases expression ISO Agbl2 (Mus musculus) 6480464 benz(a)anthracene results in increased expression of AGBL2 mRNA CTD PMID:26377693 Agbl2 Rat tetraphene multiple interactions ISO Agbl2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Agbl2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of AGBL2 mRNA CTD PMID:34492290 Agbl2 Rat titanium dioxide decreases expression ISO Agbl2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of AGBL2 mRNA CTD PMID:23557971|PMID:35295148 Agbl2 Rat titanium dioxide decreases methylation ISO Agbl2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of AGBL2 gene CTD PMID:35295148 Agbl2 Rat titanium dioxide increases expression ISO Agbl2 (Mus musculus) 6480464 titanium dioxide results in increased expression of AGBL2 mRNA CTD PMID:29264374 Agbl2 Rat trichostatin A decreases expression ISO AGBL2 (Homo sapiens) 6480464 trichostatin A results in decreased expression of AGBL2 mRNA CTD PMID:24935251|PMID:26272509 Agbl2 Rat trichostatin A multiple interactions ISO AGBL2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Agbl2 Rat triphenyl phosphate affects expression ISO AGBL2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of AGBL2 mRNA CTD PMID:37042841 Agbl2 Rat triptonide increases expression ISO Agbl2 (Mus musculus) 6480464 triptonide results in increased expression of AGBL2 mRNA CTD PMID:33045310 Agbl2 Rat valproic acid decreases expression ISO AGBL2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of AGBL2 mRNA CTD PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509|PMID:28001369 Agbl2 Rat valproic acid multiple interactions ISO AGBL2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386