Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of ZNF608 mRNA | CTD | PMID:24763279 | 1,2-dimethylhydrazine | affects expression | ISO | Zfp608 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ZFP608 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ZNF608 mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZFP608 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZNF608 mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Zfp608 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFP608 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Zfp608 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ZFP608 promoter] | CTD | PMID:19654925 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ZFP608 mRNA | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | increases methylation | ISO | ZNF608 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of ZNF608 gene | CTD | PMID:31601247 | 4-hydroxyphenyl retinamide | increases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Fenretinide results in increased expression of ZNF608 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ZFP608 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ZFP608 mRNA | CTD | PMID:30047161 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ZFP608 mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ZNF608 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ZNF608 mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | ZNF608 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ZNF608 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ZNF608 mRNA | CTD | PMID:21934132 | alpha-pinene | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ZNF608 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ZNF608 mRNA | CTD | PMID:32699268 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ZFP608 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ZNF608 mRNA and aristolochic acid I results in decreased expression of ZNF608 protein | CTD | PMID:33212167 | arsane | affects methylation | ISO | ZNF608 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZNF608 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | ZNF608 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZNF608 gene | CTD | PMID:25304211 | arsenite(3-) | increases methylation | ISO | ZNF608 (Homo sapiens) | 6480464 | arsenite results in increased methylation of ZNF608 promoter | CTD | PMID:23974009 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of ZFP608 gene | CTD | PMID:35440735 | benzo[a]pyrene | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ZFP608 mRNA | CTD | PMID:21569818 and PMID:23735875 | benzo[a]pyrene | increases methylation | ISO | ZNF608 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZNF608 exon and Benzo(a)pyrene results in increased methylation of ZNF608 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | affects expression | ISO | ZNF608 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZFP608 protein and bisphenol A results in decreased expression of ZNF608 mRNA | CTD | PMID:24552547 and PMID:25181051 | bisphenol A | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ZNF608 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ZFP608 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ZNF608 mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ZFP608 gene | CTD | PMID:28505145 | carbon nanotube | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of ZFP608 mRNA | CTD | PMID:25554681 | choline | multiple interactions | ISO | Zfp608 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ZFP608 mRNA | CTD | PMID:20938992 | cisplatin | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ZNF608 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of ZNF608 mRNA | CTD | PMID:27392435 | cyclosporin A | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ZNF608 mRNA | CTD | PMID:20106945 and PMID:27989131 | DDT | decreases expression | EXP | | 6480464 | DDT results in decreased expression of ZFP608 mRNA | CTD | PMID:30207508 | dichloroacetic acid | increases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of ZFP608 mRNA | CTD | PMID:28962523 | dorsomorphin | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ZNF608 mRNA | CTD | PMID:29803840 | fluoranthene | multiple interactions | ISO | Zfp608 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of ZFP608 mRNA | CTD | PMID:28329830 | folic acid | multiple interactions | ISO | Zfp608 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ZFP608 mRNA | CTD | PMID:20938992 | folic acid | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ZFP608 mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of ZNF608 mRNA | CTD | PMID:28937961 | FR900359 | affects phosphorylation | ISO | ZNF608 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ZNF608 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ZNF608 gene | CTD | PMID:31601247 | L-methionine | multiple interactions | ISO | Zfp608 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ZFP608 mRNA | CTD | PMID:20938992 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ZFP608 mRNA | CTD | PMID:30047161 | methylmercury chloride | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of ZNF608 mRNA | CTD | PMID:27188386 | methylmercury chloride | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ZNF608 mRNA | CTD | PMID:28001369 | nickel sulfate | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of ZNF608 mRNA | CTD | PMID:22714537 | ozone | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ZNF608 mRNA more ... | CTD | PMID:32699268 | paracetamol | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ZNF608 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ZFP608 mRNA | CTD | PMID:33387578 | pirinixic acid | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ZNF608 mRNA | CTD | PMID:19710929 | potassium chromate | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ZNF608 mRNA | CTD | PMID:22714537 | propanal | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of ZNF608 mRNA | CTD | PMID:26079696 | quercetin | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of ZNF608 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of ZNF608 mRNA | CTD | PMID:23557933 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of ZNF608 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ZNF608 mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ZNF608 mRNA | CTD | PMID:22714537 | sodium fluoride | increases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of ZFP608 mRNA | CTD | PMID:27862939 | sotorasib | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ZNF608 mRNA | CTD | PMID:36139627 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of ZFP608 mRNA | CTD | PMID:30047161 | sulforaphane | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of ZNF608 mRNA | CTD | PMID:26833863 | temozolomide | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ZNF608 mRNA | CTD | PMID:31758290 | testosterone | increases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Testosterone deficiency results in increased expression of ZFP608 mRNA | CTD | PMID:33848595 | testosterone | multiple interactions | ISO | Zfp608 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:33848595 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ZNF608 mRNA | CTD | PMID:23411599 | titanium dioxide | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ZFP608 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | ISO | Zfp608 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ZFP608 mRNA | CTD | PMID:29128614 and PMID:29264374 | trametinib | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ZNF608 mRNA | CTD | PMID:36139627 | trichostatin A | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ZNF608 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF608 mRNA | CTD | PMID:27188386 | tris(2-butoxyethyl) phosphate | affects expression | ISO | ZNF608 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of ZNF608 mRNA | CTD | PMID:29024780 | tungsten | decreases expression | ISO | Zfp608 (Mus musculus) | 6480464 | Tungsten results in decreased expression of ZFP608 mRNA | CTD | PMID:30912803 | valproic acid | affects expression | ISO | Zfp608 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ZFP608 mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZNF608 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ZNF608 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF608 mRNA | CTD | PMID:27188386 | vorinostat | increases expression | ISO | ZNF608 (Homo sapiens) | 6480464 | vorinostat results in increased expression of ZNF608 mRNA | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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