Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lrig1 | Rat | 1,1-dichloroethene | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of LRIG1 mRNA | CTD | PMID:26682919 | Lrig1 | Rat | 1,2-dichloroethane | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of LRIG1 mRNA | CTD | PMID:28960355 | Lrig1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LRIG1 mRNA | CTD | PMID:22206623 | Lrig1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of LRIG1 mRNA | CTD | PMID:22206623 | Lrig1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LRIG1 mRNA | CTD | PMID:17942748 | Lrig1 | Rat | 17beta-estradiol | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of LRIG1 mRNA | CTD | PMID:30165855 | Lrig1 | Rat | 17beta-estradiol | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of LRIG1 mRNA | CTD | PMID:31614463 | Lrig1 | Rat | 17beta-estradiol | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Estradiol results in increased expression of LRIG1 mRNA | CTD | PMID:39298647 | Lrig1 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of LRIG1 mRNA | CTD | PMID:29581250 | Lrig1 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [Flame Retardants results in increased abundance of 2,2',4,4'-tetrabromodiphenyl ether] which results in decreased expression of more ... | CTD | PMID:38995820 | Lrig1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LRIG1 mRNA; LRIG1 affects the more ... | CTD | PMID:17942748|PMID:28973660 | Lrig1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases response to substance | ISO | Lrig1 (Mus musculus) | 6480464 | LRIG1 results in increased susceptibility to Tetrachlorodibenzodioxin | CTD | PMID:28973660 | Lrig1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LRIG1 mRNA | CTD | PMID:26290441 | Lrig1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LRIG1 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:26238291 | Lrig1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Lrig1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LRIG1 mRNA | CTD | PMID:21570461 | Lrig1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRIG1 mRNA | CTD | PMID:18691609 | Lrig1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Lrig1 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of LRIG1 mRNA | CTD | PMID:18648102 | Lrig1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | LRIG1 (Homo sapiens) | 6480464 | bisphenol S affects the methylation of LRIG1 gene | CTD | PMID:31601247 | Lrig1 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of LRIG1 mRNA | CTD | PMID:28973697 | Lrig1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of LRIG1 mRNA | CTD | PMID:24780913 | Lrig1 | Rat | aflatoxin B1 | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of LRIG1 mRNA | CTD | PMID:21641981 | Lrig1 | Rat | aflatoxin B1 | decreases methylation | ISO | LRIG1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LRIG1 gene | CTD | PMID:27153756 | Lrig1 | Rat | all-trans-retinoic acid | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of LRIG1 mRNA | CTD | PMID:21934132 | Lrig1 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of LRIG1 mRNA | CTD | PMID:35163327 | Lrig1 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of LRIG1 mRNA | CTD | PMID:30779732 | Lrig1 | Rat | aristolochic acid A | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of LRIG1 mRNA | CTD | PMID:33212167 | Lrig1 | Rat | arsane | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Arsenic affects the expression of LRIG1 mRNA | CTD | PMID:18414638 | Lrig1 | Rat | arsane | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Lrig1 | Rat | arsenic atom | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Arsenic affects the expression of LRIG1 mRNA | CTD | PMID:18414638 | Lrig1 | Rat | arsenic atom | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Lrig1 | Rat | benzo[a]pyrene | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of LRIG1 mRNA | CTD | PMID:22316170|PMID:26238291 | Lrig1 | Rat | benzo[a]pyrene | affects methylation | ISO | LRIG1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LRIG1 intron | CTD | PMID:30157460 | Lrig1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of LRIG1 mRNA | CTD | PMID:20382639 | Lrig1 | Rat | benzo[e]pyrene | increases methylation | ISO | LRIG1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of LRIG1 intron | CTD | PMID:30157460 | Lrig1 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of LRIG1 mRNA | CTD | PMID:31163220 | Lrig1 | Rat | bisphenol A | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LRIG1 gene | CTD | PMID:31601247 | Lrig1 | Rat | bisphenol A | decreases methylation | ISO | LRIG1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of LRIG1 gene | CTD | PMID:31601247 | Lrig1 | Rat | bisphenol F | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Lrig1 | Rat | Butylbenzyl phthalate | affects methylation | ISO | Lrig1 (Mus musculus) | 6480464 | butylbenzyl phthalate affects the methylation of LRIG1 intron | CTD | PMID:28392331 | Lrig1 | Rat | cadmium atom | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LRIG1 more ... | CTD | PMID:35301059 | Lrig1 | Rat | cadmium dichloride | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of LRIG1 mRNA | CTD | PMID:38382870 | Lrig1 | Rat | cadmium dichloride | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LRIG1 more ... | CTD | PMID:35301059 | Lrig1 | Rat | cadmium dichloride | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of LRIG1 mRNA | CTD | PMID:38568856 | Lrig1 | Rat | calcitriol | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of LRIG1 mRNA | CTD | PMID:21592394 | Lrig1 | Rat | calcitriol | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of LRIG1 mRNA | CTD | PMID:21592394 | Lrig1 | Rat | carbon nanotube | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of LRIG1 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25620056 | Lrig1 | Rat | carbon nanotube | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of LRIG1 mRNA | CTD | PMID:25554681 | Lrig1 | Rat | CGP 52608 | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LRIG1 gene] | CTD | PMID:28238834 | Lrig1 | Rat | ciguatoxin CTX1B | affects expression | ISO | Lrig1 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of LRIG1 mRNA | CTD | PMID:18353800 | Lrig1 | Rat | cisplatin | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of LRIG1 mRNA; LRIG1 protein inhibits the more ... | CTD | PMID:21431282|PMID:27392435 | Lrig1 | Rat | cisplatin | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of LRIG1 mRNA | CTD | PMID:27392435 | Lrig1 | Rat | cisplatin | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Cisplatin results in increased expression of LRIG1 mRNA | CTD | PMID:21151649 | Lrig1 | Rat | cisplatin | increases response to substance | ISO | LRIG1 (Homo sapiens) | 6480464 | LRIG1 protein results in increased susceptibility to Cisplatin | CTD | PMID:21431282 | Lrig1 | Rat | clothianidin | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | clothianidin results in increased expression of LRIG1 mRNA | CTD | PMID:31626844 | Lrig1 | Rat | copper(II) sulfate | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of LRIG1 mRNA | CTD | PMID:19549813 | Lrig1 | Rat | coumestrol | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LRIG1 mRNA; [Coumestrol co-treated with resveratrol] more ... | CTD | PMID:19167446 | Lrig1 | Rat | crocidolite asbestos | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in decreased expression of LRIG1 mRNA | CTD | PMID:29523930 | Lrig1 | Rat | cyclosporin A | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of LRIG1 mRNA | CTD | PMID:19770486 | Lrig1 | Rat | cyclosporin A | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of LRIG1 mRNA | CTD | PMID:25562108 | Lrig1 | Rat | cytarabine | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Cytarabine results in increased expression of LRIG1 mRNA | CTD | PMID:21198554 | Lrig1 | Rat | dexamethasone | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of LRIG1 mRNA | CTD | PMID:22733784 | Lrig1 | Rat | dexamethasone | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Lrig1 | Rat | Dibutyl phosphate | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of LRIG1 mRNA | CTD | PMID:37042841 | Lrig1 | Rat | dioxygen | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of LRIG1 mRNA | CTD | PMID:24205000 | Lrig1 | Rat | dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Antimony Potassium Tartrate results in decreased expression of LRIG1 mRNA | CTD | PMID:28713220 | Lrig1 | Rat | dorsomorphin | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Lrig1 | Rat | Enterolactone | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LRIG1 mRNA | CTD | PMID:19167446 | Lrig1 | Rat | ethanol | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Ethanol results in increased expression of LRIG1 mRNA | CTD | PMID:30319688 | Lrig1 | Rat | ethyl methanesulfonate | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of LRIG1 mRNA | CTD | PMID:23649840 | Lrig1 | Rat | fenthion | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of LRIG1 mRNA | CTD | PMID:34813904 | Lrig1 | Rat | fluoranthene | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of LRIG1 mRNA | CTD | PMID:28329830 | Lrig1 | Rat | folic acid | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LRIG1 mRNA | CTD | PMID:22206623 | Lrig1 | Rat | FR900359 | increases phosphorylation | ISO | LRIG1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of LRIG1 protein | CTD | PMID:37730182 | Lrig1 | Rat | fulvestrant | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LRIG1 gene | CTD | PMID:31601247 | Lrig1 | Rat | indometacin | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Lrig1 | Rat | lead diacetate | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | lead acetate results in decreased expression of LRIG1 mRNA | CTD | PMID:22613225 | Lrig1 | Rat | lead(0) | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Lead affects the expression of LRIG1 mRNA | CTD | PMID:28903495 | Lrig1 | Rat | lipopolysaccharide | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of LRIG1 mRNA | CTD | PMID:35811015 | Lrig1 | Rat | lipopolysaccharide | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of LRIG1 mRNA | CTD | PMID:35811015 | Lrig1 | Rat | manganese atom | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Lrig1 | Rat | manganese(0) | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Lrig1 | Rat | manganese(II) chloride | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Lrig1 | Rat | menadione | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of LRIG1 mRNA | CTD | PMID:20044591 | Lrig1 | Rat | methapyrilene | increases methylation | ISO | LRIG1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of LRIG1 intron | CTD | PMID:30157460 | Lrig1 | Rat | methyl methanesulfonate | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of LRIG1 mRNA | CTD | PMID:23649840 | Lrig1 | Rat | mono(2-ethylhexyl) phthalate | affects expression | ISO | Lrig1 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate affects the expression of LRIG1 mRNA | CTD | PMID:21195148 | Lrig1 | Rat | Monobutylphthalate | affects expression | ISO | Lrig1 (Mus musculus) | 6480464 | monobutyl phthalate affects the expression of LRIG1 mRNA | CTD | PMID:21195148 | Lrig1 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of LRIG1 mRNA | CTD | PMID:24810058 | Lrig1 | Rat | okadaic acid | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of LRIG1 mRNA | CTD | PMID:38832940 | Lrig1 | Rat | panobinostat | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of LRIG1 mRNA | CTD | PMID:26272509 | Lrig1 | Rat | panobinostat | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Lrig1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LRIG1 mRNA | CTD | PMID:33387578 | Lrig1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Lrig1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of LRIG1 mRNA | CTD | PMID:36331819 | Lrig1 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of LRIG1 mRNA | CTD | PMID:35163327 | Lrig1 | Rat | phenylmercury acetate | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of LRIG1 mRNA | CTD | PMID:26272509 | Lrig1 | Rat | phenylmercury acetate | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Lrig1 | Rat | pirinixic acid | decreases expression | ISO | Lrig1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LRIG1 mRNA | CTD | PMID:18445702|PMID:20813756|PMID:23811191 | Lrig1 | Rat | progesterone | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Progesterone results in increased expression of LRIG1 mRNA | CTD | PMID:20864642 | Lrig1 | Rat | quercetin | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of LRIG1 mRNA | CTD | PMID:21632981 | Lrig1 | Rat | raloxifene | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA | CTD | PMID:19059307 | Lrig1 | Rat | raloxifene | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride affects the expression of LRIG1 mRNA | CTD | PMID:14699072 | Lrig1 | Rat | resveratrol | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of LRIG1 mRNA | CTD | PMID:19167446 | Lrig1 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of LRIG1 mRNA | CTD | PMID:35811015 | Lrig1 | Rat | SB 431542 | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Lrig1 | Rat | silicon dioxide | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of LRIG1 mRNA | CTD | PMID:25895662 | Lrig1 | Rat | SM-164 | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | LRIG1 protein promotes the reaction [SM 164 results in increased expression of TNF mRNA]; LRIG1 more ... | CTD | PMID:22241084 | Lrig1 | Rat | SM-164 | affects response to substance | ISO | LRIG1 (Homo sapiens) | 6480464 | LRIG1 protein affects the susceptibility to SM 164 | CTD | PMID:22241084 | Lrig1 | Rat | sodium arsenite | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of LRIG1 mRNA | CTD | PMID:28713220 | Lrig1 | Rat | sodium arsenite | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Lrig1 | Rat | sodium arsenite | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of LRIG1 mRNA | CTD | PMID:39515575 | Lrig1 | Rat | sulforaphane | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of LRIG1 mRNA | CTD | PMID:31838189 | Lrig1 | Rat | sunitinib | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of LRIG1 mRNA | CTD | PMID:31533062 | Lrig1 | Rat | tamoxifen | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA | CTD | PMID:19059307 | Lrig1 | Rat | tamoxifen | affects expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Tamoxifen affects the expression of LRIG1 mRNA | CTD | PMID:14699072 | Lrig1 | Rat | testosterone | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of LRIG1 mRNA | CTD | PMID:21592394 | Lrig1 | Rat | testosterone | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Testosterone results in increased expression of LRIG1 mRNA | CTD | PMID:21592394 | Lrig1 | Rat | tetrachloromethane | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LRIG1 mRNA | CTD | PMID:31919559 | Lrig1 | Rat | titanium dioxide | increases methylation | ISO | Lrig1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of LRIG1 gene | CTD | PMID:35295148 | Lrig1 | Rat | trichostatin A | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of LRIG1 mRNA | CTD | PMID:24935251|PMID:26272509 | Lrig1 | Rat | trichostatin A | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Lrig1 | Rat | triptonide | increases expression | ISO | Lrig1 (Mus musculus) | 6480464 | triptonide results in increased expression of LRIG1 mRNA | CTD | PMID:33045310 | Lrig1 | Rat | urethane | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Urethane results in increased expression of LRIG1 mRNA | CTD | PMID:28818685 | Lrig1 | Rat | valproic acid | increases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LRIG1 mRNA | CTD | PMID:19101580|PMID:29154799 | Lrig1 | Rat | valproic acid | affects expression | ISO | Lrig1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of LRIG1 mRNA | CTD | PMID:17963808 | Lrig1 | Rat | valproic acid | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of LRIG1 mRNA | CTD | PMID:23179753|PMID:24935251|PMID:26272509|PMID:28001369 | Lrig1 | Rat | valproic acid | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Lrig1 | Rat | vorinostat | decreases expression | ISO | LRIG1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of LRIG1 mRNA | CTD | PMID:26272509 | Lrig1 | Rat | vorinostat | multiple interactions | ISO | LRIG1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | |






















