Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1) - Rat Genome Database

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Pathways
Gene: Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1) Rattus norvegicus
Analyze
Symbol: Lrig1
Name: leucine-rich repeats and immunoglobulin-like domains 1
RGD ID: 1306788
Description: Predicted to enable signaling receptor activity. Predicted to be involved in sensory perception of sound. Predicted to act upstream of or within hair cycle process; innervation; and otolith morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human LRIG1 (leucine rich repeats and immunoglobulin like domains 1); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine-rich repeats and immunoglobulin-like domains protein 1; LOC312574
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84128,687,723 - 128,788,219 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4128,687,723 - 128,788,219 (-)EnsemblGRCr8
mRatBN7.24127,130,899 - 127,230,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4127,130,898 - 127,231,513 (-)EnsemblmRatBN7.2
Rnor_6.04126,615,998 - 126,717,434 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4126,617,244 - 126,644,895 (-)Ensemblrn6Rnor6.0
Rnor_5.04191,129,832 - 191,231,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44128,919,630 - 129,082,488 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4116,039,860 - 116,139,967 (-)NCBICelera
RGSC_v3.14129,164,514 - 129,327,329 (-)NCBI
Cytogenetic Map4q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clothianidin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
indometacin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
SM-164  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:24086156   PMID:25340873   PMID:26935556  


Genomics

Comparative Map Data
Lrig1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84128,687,723 - 128,788,219 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4128,687,723 - 128,788,219 (-)EnsemblGRCr8
mRatBN7.24127,130,899 - 127,230,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4127,130,898 - 127,231,513 (-)EnsemblmRatBN7.2
Rnor_6.04126,615,998 - 126,717,434 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4126,617,244 - 126,644,895 (-)Ensemblrn6Rnor6.0
Rnor_5.04191,129,832 - 191,231,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44128,919,630 - 129,082,488 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4116,039,860 - 116,139,967 (-)NCBICelera
RGSC_v3.14129,164,514 - 129,327,329 (-)NCBI
Cytogenetic Map4q34NCBI
LRIG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38366,378,797 - 66,501,121 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl366,378,794 - 66,501,263 (-)Ensemblhg38GRCh38
GRCh37366,429,221 - 66,551,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36366,511,911 - 66,633,535 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34366,511,911 - 66,633,535NCBI
Celera366,375,063 - 66,496,661 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef366,446,562 - 66,568,141 (-)NCBIHuRef
CHM1_1366,380,462 - 66,502,073 (-)NCBICHM1_1
T2T-CHM13v2.0366,423,367 - 66,545,661 (-)NCBIT2T-CHM13v2.0
Lrig1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39694,581,510 - 94,677,205 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl694,581,510 - 94,677,139 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38694,604,529 - 94,700,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl694,604,529 - 94,700,158 (-)Ensemblmm10GRCm38
MGSCv37694,554,523 - 94,650,139 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36694,569,992 - 94,665,608 (-)NCBIMGSCv36mm8
Celera696,504,989 - 96,600,773 (-)NCBICelera
Cytogenetic Map6D2NCBI
cM Map643.15NCBI
Lrig1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,108,611 - 21,218,016 (+)Ensembl
ChiLan1.0NW_00495542121,108,609 - 21,219,293 (+)NCBIChiLan1.0ChiLan1.0
LRIG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2266,291,853 - 66,413,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1366,296,639 - 66,418,810 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0366,271,849 - 66,394,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1367,642,858 - 67,764,513 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl367,644,289 - 67,765,194 (-)EnsemblpanPan2panpan1.1
LRIG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12024,907,904 - 25,033,841 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2024,890,191 - 25,032,647 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2024,866,159 - 24,944,926 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02024,948,748 - 25,059,572 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2024,948,172 - 25,058,308 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12024,645,797 - 24,756,555 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02024,992,924 - 25,103,683 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02025,052,534 - 25,163,376 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lrig1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118161,718,879 - 161,849,167 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936637108,471 - 237,390 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936637108,433 - 238,723 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRIG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1347,909,011 - 48,027,384 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11347,909,002 - 48,027,396 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21352,651,474 - 52,770,251 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRIG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12227,401,399 - 27,573,395 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2227,402,851 - 27,528,331 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041139,284,707 - 139,411,562 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrig1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624773713,520 - 849,999 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624773712,193 - 850,086 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lrig1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1652,262,013 - 52,363,909 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lrig1
620 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:75
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000017384, ENSRNOT00000072624
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat

Markers in Region
D4Rat188  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84128,809,349 - 128,809,486 (+)Marker Load Pipeline
mRatBN7.24127,252,528 - 127,252,665 (+)MAPPERmRatBN7.2
Rnor_6.04126,739,594 - 126,739,730NCBIRnor6.0
Rnor_5.04191,252,661 - 191,252,797UniSTSRnor5.0
RGSC_v3.44129,049,730 - 129,049,867RGDRGSC3.4
RGSC_v3.44129,049,731 - 129,049,867UniSTSRGSC3.4
Celera4116,161,342 - 116,161,478UniSTS
RGSC_v3.14129,294,549 - 129,294,746RGD
SHRSP x BN Map456.66UniSTS
SHRSP x BN Map456.66RGD
Cytogenetic Map4q34UniSTS
D4Rat236  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84128,820,778 - 128,820,921 (+)Marker Load Pipeline
mRatBN7.24127,263,958 - 127,264,101 (+)MAPPERmRatBN7.2
Rnor_6.04126,751,159 - 126,751,301NCBIRnor6.0
Rnor_5.04191,264,226 - 191,264,368UniSTSRnor5.0
RGSC_v3.44129,061,657 - 129,061,800RGDRGSC3.4
RGSC_v3.44129,061,658 - 129,061,800UniSTSRGSC3.4
Celera4116,172,728 - 116,172,870UniSTS
RGSC_v3.14129,306,498 - 129,306,641RGD
SHRSP x BN Map457.7499UniSTS
SHRSP x BN Map457.7499RGD
Cytogenetic Map4q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017384   ⟹   ENSRNOP00000017384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4127,130,898 - 127,199,661 (-)Ensembl
Rnor_6.0 Ensembl4126,617,244 - 126,644,895 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072624   ⟹   ENSRNOP00000066785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4128,687,723 - 128,788,219 (-)Ensembl
mRatBN7.2 Ensembl4127,130,898 - 127,231,513 (-)Ensembl
Rnor_6.0 Ensembl4126,617,244 - 126,644,895 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098554   ⟹   ENSRNOP00000091141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4127,130,898 - 127,194,900 (-)Ensembl
RefSeq Acc Id: NM_001427801   ⟹   NP_001414730
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84128,687,723 - 128,788,219 (-)NCBI
RefSeq Acc Id: XM_039108763   ⟹   XP_038964691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84128,687,723 - 128,702,432 (-)NCBI
mRatBN7.24127,130,899 - 127,145,604 (-)NCBI
RefSeq Acc Id: XM_063286082   ⟹   XP_063142152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84128,687,723 - 128,733,196 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001414730 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964691 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142152 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91409 (Get FASTA)   NCBI Sequence Viewer  
  EDL91410 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066785
  ENSRNOP00000066785.3
Ensembl Acc Id: ENSRNOP00000066785   ⟸   ENSRNOT00000072624
Ensembl Acc Id: ENSRNOP00000017384   ⟸   ENSRNOT00000017384
RefSeq Acc Id: XP_038964691   ⟸   XM_039108763
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000091141   ⟸   ENSRNOT00000098554
RefSeq Acc Id: NP_001414730   ⟸   NM_001427801
- Peptide Label: precursor
- UniProtKB: M0RB60 (UniProtKB/TrEMBL),   A6IBE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142152   ⟸   XM_063286082
- Peptide Label: isoform X1
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZD84-F1-model_v2 AlphaFold D3ZD84 1-971 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306788 AgrOrtholog
BioCyc Gene G2FUF-43634 BioCyc
Ensembl Genes ENSRNOG00000012952 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072624 ENTREZGENE
  ENSRNOT00000072624.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRFN UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
NCBI Gene 312574 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT ISOFORM X1 UniProtKB/TrEMBL
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
PhenoGen Lrig1 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012952 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A6IBE2 ENTREZGENE, UniProtKB/TrEMBL
  M0RB60 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Lrig1  leucine-rich repeats and immunoglobulin-like domains 1   Lrig1_predicted  leucine-rich repeats and immunoglobulin-like domains 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lrig1_predicted  leucine-rich repeats and immunoglobulin-like domains 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED