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Gene: Tm2d2 (TM2 domain containing 2) Rattus norvegicus

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Symbol:

Tm2d2

Name:

TM2 domain containing 2

RGD ID:

1306769

Description:

Predicted to be located in membrane. Orthologous to human TM2D2 (TM2 domain containing 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

2410018g23rik; BBP-like protein 1; LOC290833; RGD1306769; similar to RIKEN cDNA 2410018G23; TM2 domain-containing protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TM2D2 (TM2 domain containing 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NELFA (negative elongation factor complex member A)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Tm2d2 (TM2 domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TM2D2 (TM2 domain containing 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tm2d2 (TM2 domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11103	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C02F5.13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tm2d2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Candidate Gene For:

Arunc2 Arunc1 Arunc4

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	73,719,331 - 73,724,853 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	73,719,332 - 73,724,981 (-)	Ensembl				GRCr8
mRatBN7.2	16	67,016,683 - 67,022,206 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	67,012,675 - 67,022,226 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	72,293,869 - 72,299,391 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	75,699,837 - 75,705,359 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	70,946,366 - 70,951,899 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	71,804,368 - 71,809,891 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	71,804,350 - 71,809,925 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	71,453,135 - 71,458,658 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	71,440,489 - 71,446,012 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	64,921,244 - 64,926,766 (-)	NCBI		Celera
RGSC_v3.1	16	71,440,754 - 71,446,277 (-)	NCBI
Cytogenetic Map	16	q12.4	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

buspirone (EXP)

chlorpyrifos (ISO)

chrysene (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

deguelin (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dimethyl sulfoxide (ISO)

epoxiconazole (ISO)

fenthion (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

iron dichloride (ISO)

nimesulide (EXP)

nitrates (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Tm2d2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	73,719,331 - 73,724,853 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	73,719,332 - 73,724,981 (-)	Ensembl				GRCr8
mRatBN7.2	16	67,016,683 - 67,022,206 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	67,012,675 - 67,022,226 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	72,293,869 - 72,299,391 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	75,699,837 - 75,705,359 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	70,946,366 - 70,951,899 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	71,804,368 - 71,809,891 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	71,804,350 - 71,809,925 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	71,453,135 - 71,458,658 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	71,440,489 - 71,446,012 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	64,921,244 - 64,926,766 (-)	NCBI		Celera
RGSC_v3.1	16	71,440,754 - 71,446,277 (-)	NCBI
Cytogenetic Map	16	q12.4	NCBI

TM2D2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	38,988,808 - 38,996,990 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	38,988,808 - 38,996,824 (-)	Ensembl			hg38	GRCh38
GRCh37	8	38,846,327 - 38,854,028 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	38,965,484 - 38,973,198 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	8	37,797,825 - 37,805,586 (-)	NCBI		Celera
Cytogenetic Map	8	p11.22	NCBI
HuRef	8	37,379,168 - 37,386,883 (-)	NCBI		HuRef
CHM1_1	8	39,048,404 - 39,056,118 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	39,265,950 - 39,274,132 (-)	NCBI		T2T-CHM13v2.0

Tm2d2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	25,507,227 - 25,513,276 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	25,507,227 - 25,513,276 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	25,017,211 - 25,023,260 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	25,017,211 - 25,023,260 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	26,127,683 - 26,133,732 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	26,482,825 - 26,488,804 (+)	NCBI		MGSCv36	mm8
Celera	8	26,484,819 - 26,490,229 (+)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	13.7	NCBI

Tm2d2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	14,537,919 - 14,545,823 (-)	Ensembl
ChiLan1.0	NW_004955463	14,537,902 - 14,545,147 (-)	NCBI	ChiLan1.0	ChiLan1.0

TM2D2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	57,551,201 - 57,558,934 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	33,270,676 - 33,276,412 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	38,290,204 - 38,297,903 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	35,466,949 - 35,472,985 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	35,466,949 - 35,472,985 (-)	Ensembl			panPan2	panpan1.1

TM2D2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	26,551,563 - 26,557,554 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	26,551,628 - 26,556,285 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	27,073,125 - 27,079,548 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	28,383,184 - 28,389,618 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	28,383,188 - 28,389,614 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	26,676,903 - 26,683,328 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	27,253,614 - 27,260,037 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	27,291,910 - 27,298,338 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tm2d2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	49,159,956 - 49,163,023 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936710	2,297,247 - 2,301,232 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936710	2,298,233 - 2,301,239 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TM2D2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	47,601,616 - 47,611,804 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	47,601,940 - 47,611,802 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	54,674,879 - 54,684,745 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TM2D2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	37,011,616 - 37,017,621 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	37,009,511 - 37,017,474 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666052	4,962,725 - 4,969,314 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tm2d2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	4,612,124 - 4,618,211 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624780	4,612,830 - 4,618,444 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tm2d2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	61,436,859 - 61,442,463 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tm2d2
37 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	419
Count of miRNA genes:	214
Interacting mature miRNAs:	261
Transcripts:	ENSRNOT00000022425
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	36928782	81928782	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	62414464	75736480	Rat
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	32361043	77361043	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	31058039	76058039	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	59428714	91442908	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	34398294	79398294	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	31885271	76885271	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	59428714	91442908	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	59428714	91442908	Rat

Markers in Region

RH127392

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	67,016,882 - 67,017,063 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	71,804,568 - 71,804,748	NCBI	Rnor6.0
Rnor_5.0	16	71,453,335 - 71,453,515	UniSTS	Rnor5.0
RGSC_v3.4	16	71,440,689 - 71,440,869	UniSTS	RGSC3.4
Celera	16	64,921,444 - 64,921,624	UniSTS
RH 3.4 Map	16	633.1	UniSTS
Cytogenetic Map	16	q12.4	UniSTS

RH136732

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	67,022,996 - 67,023,132 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	71,810,682 - 71,810,817	NCBI	Rnor6.0
Rnor_5.0	16	71,459,449 - 71,459,584	UniSTS	Rnor5.0
RGSC_v3.4	16	71,446,803 - 71,446,938	UniSTS	RGSC3.4
Celera	16	64,927,557 - 64,927,692	UniSTS
RH 3.4 Map	16	624.5	UniSTS
Cytogenetic Map	16	q12.4	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001017444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC093382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022425 ⟹ ENSRNOP00000022425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	73,719,332 - 73,724,853 (-)	Ensembl
mRatBN7.2 Ensembl	16	67,016,683 - 67,022,226 (-)	Ensembl
Rnor_6.0 Ensembl	16	71,804,350 - 71,809,925 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112655 ⟹ ENSRNOP00000094884

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	67,012,675 - 67,022,184 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000168028 ⟹ ENSRNOP00000100705

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	73,722,272 - 73,724,981 (-)	Ensembl

RefSeq Acc Id:

NM_001017444 ⟹ NP_001017444

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	73,719,331 - 73,724,853 (-)	NCBI
mRatBN7.2	16	67,016,683 - 67,022,206 (-)	NCBI
Rnor_6.0	16	71,804,368 - 71,809,891 (-)	NCBI
Rnor_5.0	16	71,453,135 - 71,458,658 (-)	NCBI
RGSC_v3.4	16	71,440,489 - 71,446,012 (-)	RGD
Celera	16	64,921,244 - 64,926,766 (-)	RGD

Sequence:

show sequence

CAGCGCCCGGCTTGGGTCGGCCGTGGCGGCCTGGCTGTTTTTAGGCCAGGTCTCTAGGACCGGC
CCGGAAGATGGTGCTGGGCGGTTGCCCTGTGAGTTACCTATTGCTATGCGGCCAGGCGGCCTTG
CTTTTGGGGAACCTGCTGCTGCTGCACTGTGTCTCTCGGAGCCACTCGTTTAATGCTACGGCCG
AACTGGATCTCACCCCCTCAGGCGCCGCTCACCTCGAGGGTCCCGCGGCCTCGAGCTGGGAATA
CAGTGACCCCAACTCTCCAGTCATCCTTTGCTCTTACCTACCCGACGAGTTTGTAGATTGCGAT
GCCCCAGTGGATCACGTTGGAAATGCAACTGCATACCAGGAACTTGGTTATGGTTGTCTCAAGT
TTGGGGGTCAGGCCTACAGTGATGTGGAACACACTGCAGTCCAGTGCAGAGCCCTGGAGGGAAT
CGAGTGTGCCAGCCCCAGGACCTTCCTACGAAAAAATAAGCCTTGTATAAAGTACACTGGACAC
TACTTCATAACCACGCTTCTCTACTCCTTCTTCCTGGGATGCTTCGGAGTCGACCGCTTCTGTC
TGGGACACACTGGAACAGCGGTTGGGAAGCTGCTAACCCTTGGAGGACTGGGGATCTGGTGGTT
CGTCGATCTTATTTTGCTCATCACTGGGGGGCTGATGCCTAGTGACGGCAGCAACTGGTGTACT
GTCTACTAAACGTGGCTGCTGCCCTCTGCCGGCAACTGGTGTACTGTCTACTAAGCACGGCTGC
TGTCCTCTGCCGGCCAGGGAAGCGAGCATTTGGCTGGCGGGATAATTAGGAGAAGCTCTGAATT
CTCTGAACATCACCGTCCTCTTTAGGAGGAAGGACCGACCGAGTTTTTCAACCCAAATCTTAAC
CTTGCAGACCAGAATGACAAGCAGTATTGTGGGAGCCCAGTCATACCTTGCCTCACATACAAAA
GCTCAAAGCTCAAAGACAGTGACTTTTATCCAGAGATCATTTTCAGTGATGTTTCTGTGTGGCT
GGATTTCAGTCGTTTGGAGCAGGGGGACCCAGTAGGATAAACCGAGGGAATGTTTAACCACTCA
CAGCCTTTTGTGACCCTCAGTTTTCATGCACAGATGAGAAGCTGCGCCAGGGAGAAGTCTTGAG
AATATAGAAATGACTGGATTTTAATACACACCAAAAGTCTGACTCTGGGAATTTAAATTGCAAA
ATAAAGTTTTAAAACCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001017444	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH93382	(Get FASTA)	NCBI Sequence Viewer
	EDM09045	(Get FASTA)	NCBI Sequence Viewer
	EDM09046	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022425
	ENSRNOP00000094884.1
GenBank Protein	Q566R2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001017444 ⟸ NM_001017444
- Peptide Label:	precursor
- UniProtKB:	Q566R2 (UniProtKB/Swiss-Prot), A6IW26 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSFNATAELDLTPSGAAHLEGPAASSWEYSD PNSPVILCSYLPDEFVDCDAPVDHVGNATAYQELGYGCLKFGGQAYSDVEHTAVQCRALEGIEC ASPRTFLRKNKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVD LILLITGGLMPSDGSNWCTVY hide sequence

Ensembl Acc Id:

ENSRNOP00000022425 ⟸ ENSRNOT00000022425

Ensembl Acc Id:

ENSRNOP00000094884 ⟸ ENSRNOT00000112655

Ensembl Acc Id:

ENSRNOP00000100705 ⟸ ENSRNOT00000168028

Protein Domains

TM2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q566R2-F1-model_v2	AlphaFold	Q566R2	1-213	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700173

Promoter ID:

EPDNEW_R10697

Type:

multiple initiation site

Name:

Tm2d2_1

Description:

TM2 domain containing 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	71,809,890 - 71,809,950	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306769	AgrOrtholog
BioCyc Gene	G2FUF-10952	BioCyc
Ensembl Genes	ENSRNOG00000016559	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022425	ENTREZGENE
	ENSRNOT00000112655.1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7389050	IMAGE-MGC_LOAD
InterPro	TM2	UniProtKB/Swiss-Prot
	TM2_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:290833	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112677	IMAGE-MGC_LOAD
NCBI Gene	290833	ENTREZGENE
PANTHER	BETA-AMYLOID BINDING PROTEIN-RELATED	UniProtKB/Swiss-Prot
	TM2 DOMAIN-CONTAINING PROTEIN 2	UniProtKB/Swiss-Prot
Pfam	TM2	UniProtKB/Swiss-Prot
PhenoGen	Tm2d2	PhenoGen
RatGTEx	ENSRNOG00000016559	RatGTEx
UniProt	A0A8L2QCW5_RAT	UniProtKB/TrEMBL
	A6IW26	ENTREZGENE, UniProtKB/TrEMBL
	A6IW27_RAT	UniProtKB/TrEMBL
	Q566R2	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Tm2d2	TM2 domain containing 2	RGD1306769	similar to RIKEN cDNA 2410018G23	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1306769	similar to RIKEN cDNA 2410018G23	RGD1306769_predicted	similar to RIKEN cDNA 2410018G23 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306769_predicted	similar to RIKEN cDNA 2410018G23 (predicted)	LOC290833_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC290833_predicted	similar to RIKEN cDNA 2410018G23 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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