Tpd52 (tumor protein D52) - Rat Genome Database

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Gene: Tpd52 (tumor protein D52) Rattus norvegicus
Analyze
Symbol: Tpd52
Name: tumor protein D52
RGD ID: 1306767
Description: Predicted to enable calcium ion binding activity and protein homodimerization activity. Predicted to be involved in B cell differentiation and positive regulation of cell population proliferation. Predicted to be located in endoplasmic reticulum and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and glutamatergic synapse. Orthologous to human TPD52 (tumor protein D52); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calcium regulated heat stable protein-28; Crhsp-28; LOC294900; PrLZ
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8294,642,514 - 94,723,442 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl294,642,585 - 94,724,241 (+)EnsemblGRCr8
mRatBN7.2292,735,365 - 92,816,079 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl292,735,620 - 92,816,622 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx299,253,171 - 99,333,682 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0297,374,199 - 97,454,716 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0292,431,077 - 92,511,587 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0294,959,732 - 95,041,277 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl295,008,311 - 95,040,514 (+)Ensemblrn6Rnor6.0
Rnor_5.02114,703,298 - 114,784,828 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4294,850,203 - 94,880,802 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera288,371,535 - 88,402,143 (+)NCBICelera
RGSC_v3.1294,746,872 - 94,825,548 (+)NCBI
Cytogenetic Map2q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-nitrofluorene  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bicalutamide  (ISO)
bisphenol A  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
D-mannitol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicyclanil  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
mitoxantrone  (ISO)
nickel sulfate  (ISO)
nifedipine  (ISO)
Nutlin-3  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
potassium chromate  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tolbutamide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8940165   PMID:9484778   PMID:10942595   PMID:12105190   PMID:14519786   PMID:14977633   PMID:15576473   PMID:16112108   PMID:17314271   PMID:19732746   PMID:20032513   PMID:23868405  
PMID:24413018  


Genomics

Comparative Map Data
Tpd52
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8294,642,514 - 94,723,442 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl294,642,585 - 94,724,241 (+)EnsemblGRCr8
mRatBN7.2292,735,365 - 92,816,079 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl292,735,620 - 92,816,622 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx299,253,171 - 99,333,682 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0297,374,199 - 97,454,716 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0292,431,077 - 92,511,587 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0294,959,732 - 95,041,277 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl295,008,311 - 95,040,514 (+)Ensemblrn6Rnor6.0
Rnor_5.02114,703,298 - 114,784,828 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4294,850,203 - 94,880,802 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera288,371,535 - 88,402,143 (+)NCBICelera
RGSC_v3.1294,746,872 - 94,825,548 (+)NCBI
Cytogenetic Map2q23NCBI
TPD52
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38880,031,082 - 80,171,564 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl880,034,745 - 80,231,232 (-)Ensemblhg38GRCh38
GRCh37880,943,317 - 81,083,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36881,109,658 - 81,246,391 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34881,110,303 - 81,246,324NCBI
Celera876,951,325 - 77,088,299 (-)NCBICelera
Cytogenetic Map8q21.13NCBI
HuRef876,436,252 - 76,573,212 (-)NCBIHuRef
CHM1_1880,999,297 - 81,135,937 (-)NCBICHM1_1
T2T-CHM13v2.0880,462,421 - 80,603,125 (-)NCBIT2T-CHM13v2.0
Tpd52
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3938,991,590 - 9,069,824 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl38,990,653 - 9,069,783 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3838,926,530 - 9,005,393 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl38,925,593 - 9,004,723 (-)Ensemblmm10GRCm38
MGSCv3738,929,436 - 9,004,515 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3638,912,509 - 8,987,588 (-)NCBIMGSCv36mm8
Celera38,932,906 - 9,011,073 (-)NCBICelera
Cytogenetic Map3A1NCBI
cM Map32.23NCBI
Tpd52
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554441,230,730 - 1,264,526 (+)Ensembl
ChiLan1.0NW_0049554441,230,730 - 1,261,839 (+)NCBIChiLan1.0ChiLan1.0
TPD52
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2795,654,079 - 95,911,079 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1871,284,034 - 71,541,339 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0876,562,979 - 76,698,329 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1878,070,481 - 78,324,726 (-)NCBIPanPan1.1PanPan1.1panPan2
TPD52
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12927,418,239 - 27,524,919 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2927,419,736 - 27,525,336 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2927,692,919 - 27,800,319 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02927,542,727 - 27,650,638 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2927,542,727 - 27,651,067 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12927,595,932 - 27,704,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02927,627,261 - 27,734,743 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02927,983,550 - 28,092,220 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tpd52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530351,615,872 - 51,678,313 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366563,827,636 - 3,869,051 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366563,827,764 - 3,868,828 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPD52
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl456,471,897 - 56,603,617 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1456,472,992 - 56,603,616 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2461,913,498 - 61,946,995 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TPD52
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1875,482,413 - 75,616,018 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603965,584,303 - 65,824,509 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpd52
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474411,099,769 - 11,201,758 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tpd52
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13143,061,398 - 143,140,444 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tpd52
992 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:38
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000015327
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)261556902106556902Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)282947902127947902Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)284056790132859658Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)278269809104744824Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)261051541105724065Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)293602631145807373Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)261051883104684275Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)282214549127214549Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)261051541105724065Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)260861391105861391Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat

Markers in Region
AA925951  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2292,815,855 - 92,816,012 (+)MAPPERmRatBN7.2
Rnor_6.0295,040,260 - 95,040,415NCBIRnor6.0
Rnor_5.02114,783,811 - 114,783,966UniSTSRnor5.0
RGSC_v3.4294,881,986 - 94,882,141UniSTSRGSC3.4
Celera288,403,327 - 88,403,482UniSTS
RH 3.4 Map2578.2UniSTS
Cytogenetic Map2q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ499323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015327   ⟹   ENSRNOP00000015327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl292,784,058 - 92,814,674 (+)Ensembl
Rnor_6.0 Ensembl295,008,477 - 95,039,076 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077270   ⟹   ENSRNOP00000074488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl294,691,338 - 94,723,440 (+)Ensembl
mRatBN7.2 Ensembl292,784,058 - 92,814,457 (+)Ensembl
Rnor_6.0 Ensembl295,008,311 - 95,040,514 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099506   ⟹   ENSRNOP00000085840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl294,642,997 - 94,724,241 (+)Ensembl
mRatBN7.2 Ensembl292,735,620 - 92,814,674 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112708   ⟹   ENSRNOP00000086815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl294,642,972 - 94,723,440 (+)Ensembl
mRatBN7.2 Ensembl292,735,640 - 92,814,457 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117383   ⟹   ENSRNOP00000081198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl294,643,004 - 94,723,280 (+)Ensembl
mRatBN7.2 Ensembl292,735,620 - 92,814,457 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120271   ⟹   ENSRNOP00000085537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl292,735,666 - 92,816,622 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149178   ⟹   ENSRNOP00000101990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl294,642,585 - 94,724,238 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172046   ⟹   ENSRNOP00000110691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl294,642,585 - 94,724,237 (+)Ensembl
RefSeq Acc Id: NM_001106421   ⟹   NP_001099891
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,691,367 - 94,723,282 (+)NCBI
mRatBN7.2292,783,989 - 92,815,920 (+)NCBI
Rnor_6.0295,008,477 - 95,039,076 (+)NCBI
Rnor_5.02114,703,298 - 114,784,828 (+)NCBI
RGSC_v3.4294,850,203 - 94,880,802 (+)RGD
Celera288,371,535 - 88,402,143 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401807   ⟹   NP_001388736
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,749 - 94,723,282 (+)NCBI
mRatBN7.2292,735,365 - 92,815,920 (+)NCBI
RefSeq Acc Id: NM_001401808   ⟹   NP_001388737
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,749 - 94,723,282 (+)NCBI
mRatBN7.2292,735,365 - 92,815,920 (+)NCBI
RefSeq Acc Id: XM_006232143   ⟹   XP_006232205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,691,157 - 94,723,442 (+)NCBI
mRatBN7.2292,783,813 - 92,816,079 (+)NCBI
Rnor_6.0295,007,839 - 95,041,277 (+)NCBI
Rnor_5.02114,703,298 - 114,784,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760862   ⟹   XP_008759084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,691,191 - 94,723,442 (+)NCBI
mRatBN7.2292,783,813 - 92,816,079 (+)NCBI
Rnor_6.0295,007,840 - 95,041,277 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101964   ⟹   XP_038957892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,691,191 - 94,723,442 (+)NCBI
mRatBN7.2292,783,813 - 92,816,079 (+)NCBI
RefSeq Acc Id: XM_063281536   ⟹   XP_063137606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,514 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281537   ⟹   XP_063137607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,514 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281538   ⟹   XP_063137608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,514 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281539   ⟹   XP_063137609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,514 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281540   ⟹   XP_063137610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,514 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281541   ⟹   XP_063137611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,642,514 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281542   ⟹   XP_063137612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,675,347 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281543   ⟹   XP_063137613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,675,328 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281544   ⟹   XP_063137614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,656,121 - 94,723,442 (+)NCBI
RefSeq Acc Id: XM_063281545   ⟹   XP_063137615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8294,675,289 - 94,723,442 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099891 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388736 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388737 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416689 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416690 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416691 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416692 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416693 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416694 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232205 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759084 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957892 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137606 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137607 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137608 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137609 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137610 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137611 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137612 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137613 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137614 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137615 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ACY08775 (Get FASTA)   NCBI Sequence Viewer  
  EDM01014 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074488
  ENSRNOP00000074488.3
  ENSRNOP00000081198
  ENSRNOP00000081198.2
  ENSRNOP00000085840.2
  ENSRNOP00000086815.2
  ENSRNOP00000101990
  ENSRNOP00000101990.1
  ENSRNOP00000110691
  ENSRNOP00000110691.1
RefSeq Acc Id: NP_001099891   ⟸   NM_001106421
- Peptide Label: isoform 1
- UniProtKB: A6IH66 (UniProtKB/TrEMBL),   D0UFD0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232205   ⟸   XM_006232143
- Peptide Label: isoform X8
- UniProtKB: A0A0G2K865 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759084   ⟸   XM_008760862
- Peptide Label: isoform X9
- UniProtKB: D0UFD0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074488   ⟸   ENSRNOT00000077270
Ensembl Acc Id: ENSRNOP00000015327   ⟸   ENSRNOT00000015327
RefSeq Acc Id: XP_038957892   ⟸   XM_039101964
- Peptide Label: isoform X10
- UniProtKB: D0UFD0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085840   ⟸   ENSRNOT00000099506
Ensembl Acc Id: ENSRNOP00000081198   ⟸   ENSRNOT00000117383
Ensembl Acc Id: ENSRNOP00000085537   ⟸   ENSRNOT00000120271
Ensembl Acc Id: ENSRNOP00000086815   ⟸   ENSRNOT00000112708
RefSeq Acc Id: NP_001388736   ⟸   NM_001401807
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZRF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388737   ⟸   NM_001401808
- Peptide Label: isoform 3
- UniProtKB: A0A8I5ZRF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137606   ⟸   XM_063281536
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137608   ⟸   XM_063281538
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063137607   ⟸   XM_063281537
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063137609   ⟸   XM_063281539
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063137611   ⟸   XM_063281541
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063137610   ⟸   XM_063281540
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063137614   ⟸   XM_063281544
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A6K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137615   ⟸   XM_063281545
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A6K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137613   ⟸   XM_063281543
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063137612   ⟸   XM_063281542
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K865 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101990   ⟸   ENSRNOT00000149178
Ensembl Acc Id: ENSRNOP00000110691   ⟸   ENSRNOT00000172046

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K865-F1-model_v2 AlphaFold A0A0G2K865 1-247 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691241
Promoter ID:EPDNEW_R1764
Type:multiple initiation site
Name:Tpd52_1
Description:tumor protein D52
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0295,008,444 - 95,008,504EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306767 AgrOrtholog
BioCyc Gene G2FUF-53729 BioCyc
Ensembl Genes ENSRNOG00000011441 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077270 ENTREZGENE
  ENSRNOT00000077270.3 UniProtKB/TrEMBL
  ENSRNOT00000099506.2 UniProtKB/TrEMBL
  ENSRNOT00000112708.2 UniProtKB/TrEMBL
  ENSRNOT00000117383 ENTREZGENE
  ENSRNOT00000117383.2 UniProtKB/TrEMBL
  ENSRNOT00000149178 ENTREZGENE
  ENSRNOT00000149178.1 UniProtKB/TrEMBL
  ENSRNOT00000172046 ENTREZGENE
  ENSRNOT00000172046.1 UniProtKB/TrEMBL
InterPro TPD52 UniProtKB/TrEMBL
KEGG Report rno:294900 UniProtKB/TrEMBL
NCBI Gene 294900 ENTREZGENE
PANTHER TPD52 UniProtKB/TrEMBL
  TUMOR PROTEIN D52 UniProtKB/TrEMBL
Pfam TPD52 UniProtKB/TrEMBL
PhenoGen Tpd52 PhenoGen
RatGTEx ENSRNOG00000011441 RatGTEx
UniProt A0A0G2K865 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRF0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A482_RAT UniProtKB/TrEMBL
  A0A8I6A6K8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LBP7_RAT UniProtKB/TrEMBL
  A0ABK0LIH3_RAT UniProtKB/TrEMBL
  A6IH66 ENTREZGENE, UniProtKB/TrEMBL
  D0UFD0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tpd52  tumor protein D52   Tpd52_predicted  tumor protein D52 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tpd52_predicted  tumor protein D52 (predicted)      Symbol and Name status set to approved 70820 APPROVED