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Gene: Ccdc81 (coiled-coil domain containing 81) Rattus norvegicus

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Symbol:

Ccdc81

Name:

coiled-coil domain containing 81

RGD ID:

1306766

Description:

Predicted to enable DNA binding activity. Predicted to be located in centrosome. Predicted to be active in microtubule organizing center. Orthologous to human CCDC81 (coiled-coil domain containing 81); INTERACTS WITH bisphenol A; Cuprizon; cyclosporin A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

coiled-coil domain-containing protein 81; LOC308810; RGD1306766; similar to hypothetical protein FLJ23514

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CCDC81 (coiled-coil domain containing 81)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ccdc81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ccdc81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CCDC81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CCDC81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ccdc81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CCDC81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CCDC81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ccdc81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ccdc81 (coiled-coil domain containing 81)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ccdc81 (coiled-coil domain containing 81)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CCDC81 (coiled-coil domain containing 81)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ccdc81	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ccdc81	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	153,152,032 - 153,203,586 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	153,152,034 - 153,203,984 (-)	Ensembl				GRCr8
mRatBN7.2	1	143,739,472 - 143,791,026 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	143,739,474 - 143,790,926 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	151,680,220 - 151,731,567 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	158,856,598 - 158,907,951 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	151,730,519 - 151,781,861 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	154,064,132 - 154,111,999 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	154,064,256 - 154,111,725 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	160,368,406 - 160,416,901 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	146,430,204 - 146,487,051 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	141,982,546 - 142,033,784 (-)	NCBI		Celera
RGSC_v3.1	1	146,508,610 - 146,565,457 (-)	NCBI
Cytogenetic Map	1	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

Cuprizon (EXP)

cyclosporin A (EXP)

decabromodiphenyl ether (EXP)

furan (EXP)

imidacloprid (EXP)

N,N-diethyl-m-toluamide (EXP)

ozone (ISO)

paracetamol (ISO)

permethrin (EXP)

quercetin (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

tetraphene (ISO)

titanium dioxide (ISO)

triadimefon (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

centrosome (IEA,ISO,ISS)

ciliary basal body (IEA,ISO)

microtubule organizing center (IBA)

Molecular Function

DNA binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:25074808

Genomics

Comparative Map Data

Ccdc81
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	153,152,032 - 153,203,586 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	153,152,034 - 153,203,984 (-)	Ensembl				GRCr8
mRatBN7.2	1	143,739,472 - 143,791,026 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	143,739,474 - 143,790,926 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	151,680,220 - 151,731,567 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	158,856,598 - 158,907,951 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	151,730,519 - 151,781,861 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	154,064,132 - 154,111,999 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	154,064,256 - 154,111,725 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	160,368,406 - 160,416,901 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	146,430,204 - 146,487,051 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	141,982,546 - 142,033,784 (-)	NCBI		Celera
RGSC_v3.1	1	146,508,610 - 146,565,457 (-)	NCBI
Cytogenetic Map	1	q32	NCBI

CCDC81
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	86,374,887 - 86,423,106 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	86,374,736 - 86,423,109 (+)	Ensembl			hg38	GRCh38
GRCh37	11	86,085,929 - 86,134,148 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	85,763,426 - 85,811,798 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	11	83,396,384 - 83,444,761 (+)	NCBI		Celera
Cytogenetic Map	11	q14.2	NCBI
HuRef	11	82,374,317 - 82,422,698 (+)	NCBI		HuRef
CHM1_1	11	85,971,531 - 86,019,904 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	86,317,381 - 86,365,618 (+)	NCBI		T2T-CHM13v2.0

Ccdc81
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	89,515,356 - 89,552,837 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	89,515,356 - 89,552,837 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	89,866,148 - 89,903,629 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	89,866,148 - 89,903,629 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	97,014,658 - 97,052,139 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	89,741,340 - 89,778,803 (-)	NCBI		MGSCv36	mm8
Celera	7	87,183,930 - 87,221,434 (-)	NCBI		Celera
Cytogenetic Map	7	D3	NCBI
cM Map	7	50.38	NCBI

Ccdc81
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	6,568,114 - 6,622,689 (-)	Ensembl
ChiLan1.0	NW_004955414	6,567,722 - 6,623,043 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCDC81
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	87,286,144 - 87,346,552 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	88,344,597 - 88,397,391 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	81,430,816 - 81,480,782 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	85,038,184 - 85,086,480 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	85,038,184 - 85,086,480 (+)	Ensembl			panPan2	panpan1.1

CCDC81
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	13,132,636 - 13,173,788 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	13,132,629 - 13,174,127 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	12,998,130 - 13,039,206 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	13,315,277 - 13,356,411 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	13,315,288 - 13,356,601 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	13,101,126 - 13,142,337 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	13,173,379 - 13,214,444 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	13,229,792 - 13,271,110 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ccdc81
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	72,563,659 - 72,603,133 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936498	14,163,310 - 14,203,454 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936498	14,163,335 - 14,202,715 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC81
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	20,225,767 - 20,280,285 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	20,224,634 - 20,279,591 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	22,526,173 - 22,571,645 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC81
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	77,646,756 - 77,695,516 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	77,647,403 - 77,697,067 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	48,033,570 - 48,115,588 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc81
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624845	3,571,086 - 3,628,898 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624845	3,572,494 - 3,628,575 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ccdc81
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	111,287,027 - 111,329,351 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ccdc81
364 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	118
Count of miRNA genes:	96
Interacting mature miRNAs:	107
Transcripts:	ENSRNOT00000055488
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	131179947	176179947	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
631684	Bp117	Blood pressure QTL 117	8.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	120082258	165082258	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	112521556	157521556	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	142582180	153680016	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	141173126	169168317	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	131243790	176243790	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	129182274	174182274	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	128019551	173019551	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	108680016	153680016	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	178317588	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	112521556	157521556	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	111949780	160574007	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	12	30	136	56	55	24	33	24	6	193	93	10	110	61	87	31	3	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000055488 ⟹ ENSRNOP00000052353

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	153,152,034 - 153,203,486 (-)	Ensembl
mRatBN7.2 Ensembl	1	143,739,474 - 143,790,926 (-)	Ensembl
Rnor_6.0 Ensembl	1	154,064,256 - 154,111,725 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102115 ⟹ ENSRNOP00000080187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	153,152,034 - 153,203,984 (-)	Ensembl
mRatBN7.2 Ensembl	1	143,739,474 - 143,790,926 (-)	Ensembl

RefSeq Acc Id:

NM_001014021 ⟹ NP_001014043

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	153,152,032 - 153,203,486 (-)	NCBI
mRatBN7.2	1	143,739,472 - 143,790,926 (-)	NCBI
Rnor_6.0	1	154,064,132 - 154,111,999 (-)	NCBI
Rnor_5.0	1	160,368,406 - 160,416,901 (-)	NCBI
RGSC_v3.4	1	146,430,204 - 146,487,051 (-)	RGD
Celera	1	141,982,546 - 142,033,784 (-)	RGD

Sequence:

show sequence

GTGGATTTGCACTTCTGGCTTAGCGAGGGACAGTGCTCTGGCTTCGTGTTGGGGGAACAGGTTA
TCCGTGAGCCAGATCACTGGGGAGGGACGGCGACCAAGAATGTTTATTTAAGGAAAAATAATAT
CAAAACATATCAAGACTTTAAAAAGCACACCCTAAATTCCGGGCAAAGAGGGCTGGAGGGTGGG
AAAATCACCTTAGTGCAAACTCCATATAACAAAGAAGAGACTATCTATCTAGGACCCACCACGG
AGTCAATCGGGACCGAAGATGTTGGACAGGATTGGGCCAGGTTTTCAGGACCTGTGCAGGCAAG
TGCTGCCCACACTACCGTCGCTGAGCCAAGAGGAAGTCTCTACTATCTGGGGAAATGTTTCAGA
TTTTGTGGAACGGCAGCTAACTATGCACAAGGGAGTGCAGATTTCTGGACTTGGAACGTTCACT
TTCACGAGGCAGCAGCTTGAGATGGGAAACAAGAAGTTTGTTCTTGTGCAGAGGCCCGTGTTTA
TCATGTCAGAGAAGTTAGTGCAGACCCATGGACTCAAACAAAACAAAGTATTTTCTCCTGGTGA
TATTCCAGTTGTCCCACTTAATTTTGTCATGATATCCCTGGAGGGTCCATTTAACAGGGATACA
ATAGAGGGCTGTGTGAGAGAGACATTACTTTTTTTATCGAGATCCATTTCCATCAAACAAAATG
TGGAGTTCACATTCAAAGGAATTGGGGTCCTTTCGATCAGAGACAACAAAGTGAAGATGAGATT
TTATAAGGACTTCCTCTCTTCGGTGGACGGGAGCGGCACCTTGACTAAAGCCCTTGCAAATAGG
CCTGGCACCATGGACTCAGTGCTGTCTAGCAGAGAGTCCTTTGGAAAGCGTCCCAACAGCGCAC
TGGCCTTTCCAAGGATTGAGCACAAAGAGACGGAGAACAAACCACCCGTGGAGGTCTTTGGAGA
GGAAGGTGGAGAGAACAGACCAAGGAAGAGCAAGTTGAAAGACCAGTCAGACAAAGAAGAAGGA
GCCTGGGAGATCTCGTCGGCCAAGAAACACCGTGATAGGCAATCTATCTCTCCTGCTAAAGTGA
CAAGCGGCAGCCTGCTGGACAAGTTTGAGCGAAGTGGGAATGGGGGGAAGATCACCGAAAACTT
GTCTCCAGGTGGTCAGAGAAATGACAATGAGAAGCCCAAAACATCTCCTGCCCCAGCTTGCCAG
GATCACAATAAAGCAGGACAGGAAATGTGCTATGTGTGTTTGCAACGAGCACAACGAAATTTTG
CATTGTACTATGGAGATGAGAAGAGGAGGAGAGAGATAGAAGATGAGCGACTCATGCAGCAGTA
CCAAATTGCGAAGGACCAGGAGGCTTTCTTCAAAAGCCAGATGAAAAGTATGGCTACTAGAGAG
CAGAATCAGAAAAATGCTGCCTATAATCTTGGAGTTGCTGAAGCTATAAGGAGTCACAAGAACG
AGAAACCCGATTTTTATAAATCCTTCCTCTTTGATAAACGACCTCTTAGTCCTGAGATTAATGC
TTTTAAGCAGGAGGAATATTCCCAAAGTCTCCTGAAACAAATGGAAAGCAAACGGGAGAAGGAA
ATAAAGCAAAGACAAAACAGAGAGTTGATGGATCGCTTGGAGCAAGTGCAGCTCACAGAGGAAC
TCGCTGCACAAAGAGCTCAATATCTAAAAGAGAAGATGGAAGAAACACAGTACTATAAGAGAGC
TTTGGATGCGCAGGTAAAGAACAAACCCTCCCAGCTGCCCATGTTTGAGCCCGACTCTGCTGAG
CCCATCTTTGGTAAGAACGAGGGAGAAATGGAGATGGAAAAGCGAAAGCGAGAGCAGAGTTGCA
TGAAGCATCAGATGGAGGCAGCCGCCAACCTCAAGAGGAACACCATCCTGAACCAGCTGGTGGA
CCAGAGGCGAGATCTGCAGATGCTTCAGAGGACAAAGAGAGAGCACTTGGCAGACAGAGCTGCT
GAGGTGGATCGAGTGAACAGACTCAACCAGTGCTTGCAAGAAGATTGGGACAGGAGCCTGGCCA
TGAAGAAGCAGCGGGACTTGGAGGAAAAGGCCTTTGAGCGGGCTTCCGACAAGCTGTTTCTCTT
GGACCAGTGCGAGAAGTATCGGCGCTGCAGGCAGTGCCAGAGGCGCACCTCCAACACGGGCGAG
AGCAACGTGTGGCCCCTGAATAAGTTCCTGCAGGGCTCACGACTGCTCGTGTAGAACTCAAAGT
TTGAACCTATGTTTCCCGAGGGACATTTATTTGGAGTTGTTGAATATTTAGGGTGTGTATATTT
GTACCTCAGAGGAAAAAAAAAGATTGAGTACTTTCTAACCCTTTCTTGAAAAAAAAAAAAAAAA
AAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039113100 ⟹ XP_038969028

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	153,160,045 - 153,203,586 (-)	NCBI
mRatBN7.2	1	143,747,432 - 143,791,026 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014043	(Get FASTA)	NCBI Sequence Viewer
	XP_038969028	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83639	(Get FASTA)	NCBI Sequence Viewer
	EDM18572	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000080187
	ENSRNOP00000080187.1
GenBank Protein	Q5XIN9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014043 ⟸ NM_001014021

- UniProtKB:

Q5XIN9 (UniProtKB/Swiss-Prot), A6I608 (UniProtKB/TrEMBL), D4ADM4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLDRIGPGFQDLCRQVLPTLPSLSQEEVSTIWGNVSDFVERQLTMHKGVQISGLGTFTFTRQQL
EMGNKKFVLVQRPVFIMSEKLVQTHGLKQNKVFSPGDIPVVPLNFVMISLEGPFNRDTIEGCVR
ETLLFLSRSISIKQNVEFTFKGIGVLSIRDNKVKMRFYKDFLSSVDGSGTLTKALANRPGTMDS
VLSSRESFGKRPNSALAFPRIEHKETENKPPVEVFGEEGGENRPRKSKLKDQSDKEEGAWEISS
AKKHRDRQSISPAKVTSGSLLDKFERSGNGGKITENLSPGGQRNDNEKPKTSPAPACQDHNKAG
QEMCYVCLQRAQRNFALYYGDEKRRREIEDERLMQQYQIAKDQEAFFKSQMKSMATREQNQKNA
AYNLGVAEAIRSHKNEKPDFYKSFLFDKRPLSPEINAFKQEEYSQSLLKQMESKREKEIKQRQN
RELMDRLEQVQLTEELAAQRAQYLKEKMEETQYYKRALDAQVKNKPSQLPMFEPDSAEPIFGKN
EGEMEMEKRKREQSCMKHQMEAAANLKRNTILNQLVDQRRDLQMLQRTKREHLADRAAEVDRVN
RLNQCLQEDWDRSLAMKKQRDLEEKAFERASDKLFLLDQCEKYRRCRQCQRRTSNTGESNVWPL
NKFLQGSRLLV

hide sequence

Ensembl Acc Id:

ENSRNOP00000052353 ⟸ ENSRNOT00000055488

RefSeq Acc Id:	XP_038969028 ⟸ XM_039113100
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000080187 ⟸ ENSRNOT00000102115

Protein Domains

CCDC81 HU

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIN9-F1-model_v2	AlphaFold	Q5XIN9	1-651	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306766	AgrOrtholog
BioCyc Gene	G2FUF-58549	BioCyc
Ensembl Genes	ENSRNOG00000033733	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000102115	ENTREZGENE
	ENSRNOT00000102115.1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7134846	IMAGE-MGC_LOAD
InterPro	CCDC81_HU_dom_2	UniProtKB/Swiss-Prot
	Coiled-coil_dom_cont_p_81	UniProtKB/Swiss-Prot
	HU-CCDC81	UniProtKB/Swiss-Prot
	IHF-like_DNA-bd_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:308810	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94461	IMAGE-MGC_LOAD
NCBI Gene	308810	ENTREZGENE
PANTHER	COILED-COIL DOMAIN-CONTAINING PROTEIN 81	UniProtKB/Swiss-Prot
	PTHR14362	UniProtKB/Swiss-Prot
Pfam	HU-CCDC81_euk_1	UniProtKB/Swiss-Prot
	HU-CCDC81_euk_2	UniProtKB/Swiss-Prot
PhenoGen	Ccdc81	PhenoGen
RatGTEx	ENSRNOG00000033733	RatGTEx
Superfamily-SCOP	SSF47729	UniProtKB/Swiss-Prot
UniProt	A6I608	ENTREZGENE, UniProtKB/TrEMBL
	CCD81_RAT	UniProtKB/Swiss-Prot
	D4ADM4	ENTREZGENE, UniProtKB/TrEMBL
	Q5XIN9	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Ccdc81	coiled-coil domain containing 81	RGD1306766	similar to hypothetical protein FLJ23514	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1306766	similar to hypothetical protein FLJ23514	RGD1306766_predicted	similar to hypothetical protein FLJ23514 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306766_predicted	similar to hypothetical protein FLJ23514 (predicted)	LOC308810_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC308810_predicted	similar to hypothetical protein FLJ23514 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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