Symbol:
Zbtb49
Name:
zinc finger and BTB domain containing 49
RGD ID:
1306733
Description:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Predicted to be involved in several processes, including negative regulation of cell population proliferation; regulation of cytokine production; and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be active in nucleoplasm. Orthologous to human ZBTB49 (zinc finger and BTB domain containing 49); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC305428; Zfp509; zinc finger and BTB domain-containing protein 49; zinc finger protein 509; Znf509
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 14 76,802,988 - 76,835,573 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 14 76,802,495 - 76,824,718 (+) Ensembl GRCr8 mRatBN7.2 14 72,590,692 - 72,612,404 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 14 72,590,708 - 72,612,404 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 14 77,032,377 - 77,054,090 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 14 78,273,251 - 78,294,964 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 14 74,713,327 - 74,735,038 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 14 77,322,014 - 77,343,736 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 14 77,322,012 - 77,343,764 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 14 77,303,883 - 77,325,598 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 14 77,873,462 - 77,895,156 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 14 71,541,223 - 71,562,888 (+) NCBI Celera RGSC_v3.1 14 77,875,524 - 77,897,199 (+) NCBI Cytogenetic Map 14 q21 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Zbtb49 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 1,2-dichloroethane decreases expression ISO Zbtb49 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of ZBTB49 mRNA CTD PMID:28960355 Zbtb49 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat aflatoxin B1 increases methylation ISO ZBTB49 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ZBTB49 gene CTD PMID:27153756 Zbtb49 Rat amiodarone increases expression ISO ZBTB49 (Homo sapiens) 6480464 Amiodarone results in increased expression of ZBTB49 mRNA CTD PMID:19774075 Zbtb49 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat arsane affects methylation ISO ZBTB49 (Homo sapiens) 6480464 Arsenic affects the methylation of ZBTB49 gene CTD PMID:25304211 Zbtb49 Rat arsenic atom affects methylation ISO ZBTB49 (Homo sapiens) 6480464 Arsenic affects the methylation of ZBTB49 gene CTD PMID:25304211 Zbtb49 Rat arsenite(3-) multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to ZBTB49 mRNA] CTD PMID:32406909 Zbtb49 Rat benzo[a]pyrene increases methylation ISO ZBTB49 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ZBTB49 5' UTR CTD PMID:27901495 Zbtb49 Rat benzo[a]pyrene decreases methylation ISO Zbtb49 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of ZBTB49 exon; Benzo(a)pyrene results in decreased methylation of ZBTB49 more ... CTD PMID:27901495 Zbtb49 Rat bis(2-ethylhexyl) phthalate increases expression ISO Zbtb49 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of ZBTB49 mRNA CTD PMID:34319233 Zbtb49 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ZBTB49 mRNA CTD PMID:25181051 Zbtb49 Rat bisphenol A affects splicing ISO Zbtb49 (Mus musculus) 6480464 bisphenol A affects the splicing of ZBTB49 mRNA CTD PMID:37894381 Zbtb49 Rat bisphenol F decreases expression ISO Zbtb49 (Mus musculus) 6480464 bisphenol F results in decreased expression of ZBTB49 mRNA CTD PMID:38685157 Zbtb49 Rat C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of ZBTB49 mRNA CTD PMID:19167457 Zbtb49 Rat cadmium atom multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ZBTB49 more ... CTD PMID:35301059 Zbtb49 Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZBTB49 more ... CTD PMID:39012411 Zbtb49 Rat cadmium dichloride multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ZBTB49 more ... CTD PMID:35301059 Zbtb49 Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZBTB49 more ... CTD PMID:39012411 Zbtb49 Rat caffeine decreases phosphorylation ISO ZBTB49 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of ZBTB49 protein CTD PMID:35688186 Zbtb49 Rat CGP 52608 multiple interactions ISO ZBTB49 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ZBTB49 gene] CTD PMID:28238834 Zbtb49 Rat cyclosporin A increases expression ISO ZBTB49 (Homo sapiens) 6480464 Cyclosporine results in increased expression of ZBTB49 mRNA CTD PMID:20106945 Zbtb49 Rat fipronil decreases expression EXP 6480464 fipronil results in decreased expression of ZBTB49 mRNA CTD PMID:34044035 Zbtb49 Rat folic acid increases expression ISO Zbtb49 (Mus musculus) 6480464 Folic Acid results in increased expression of ZBTB49 mRNA CTD PMID:25629700 Zbtb49 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat paracetamol affects expression ISO Zbtb49 (Mus musculus) 6480464 Acetaminophen affects the expression of ZBTB49 mRNA CTD PMID:17562736 Zbtb49 Rat PCB138 multiple interactions ISO Zbtb49 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zbtb49 Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of ZBTB49 mRNA CTD PMID:19281266 Zbtb49 Rat sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of ZBTB49 mRNA CTD PMID:30047161 Zbtb49 Rat sunitinib increases expression ISO ZBTB49 (Homo sapiens) 6480464 Sunitinib results in increased expression of ZBTB49 mRNA CTD PMID:31533062 Zbtb49 Rat titanium dioxide decreases methylation ISO Zbtb49 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ZBTB49 gene CTD PMID:35295148 Zbtb49 Rat triphenyl phosphate affects expression ISO ZBTB49 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ZBTB49 mRNA CTD PMID:37042841 Zbtb49 Rat triptonide increases expression ISO Zbtb49 (Mus musculus) 6480464 triptonide results in increased expression of ZBTB49 mRNA CTD PMID:33045310 Zbtb49 Rat trovafloxacin increases expression ISO Zbtb49 (Mus musculus) 6480464 trovafloxacin results in increased expression of ZBTB49 mRNA CTD PMID:35537566 Zbtb49 Rat valproic acid increases methylation ISO ZBTB49 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ZBTB49 gene CTD PMID:29154799