Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NRAP mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NRAP mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | Estradiol results in decreased expression of NRAP mRNA | CTD | PMID:19484750 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nrap (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NRAP mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NRAP mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of NRAP mRNA | CTD | PMID:30071829 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Nrap (Mus musculus) | 6480464 | bisphenol S affects the methylation of NRAP gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of NRAP mRNA | CTD | PMID:25825206 and PMID:30047161 | aflatoxin B1 | decreases methylation | ISO | NRAP (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of NRAP exon and Aflatoxin B1 results in decreased methylation of NRAP intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of NRAP exon | CTD | PMID:30157460 | all-trans-retinoic acid | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NRAP mRNA | CTD | PMID:36189433 | benzo[a]pyrene | increases expression | ISO | NRAP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NRAP mRNA | CTD | PMID:22316170 | benzo[a]pyrene | affects methylation | ISO | NRAP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of NRAP exon | CTD | PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NRAP promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of NRAP mRNA | CTD | PMID:22228805 | benzo[a]pyrene | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of NRAP mRNA] | CTD | PMID:22228805 | benzo[e]pyrene | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of NRAP exon | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NRAP mRNA | CTD | PMID:25181051 and PMID:27178563 | cantharidin | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | Cantharidin results in decreased expression of NRAP mRNA | CTD | PMID:36907384 | captan | increases expression | ISO | Nrap (Mus musculus) | 6480464 | Captan results in increased expression of NRAP mRNA | CTD | PMID:31558096 | CGP 52608 | multiple interactions | ISO | NRAP (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NRAP gene] | CTD | PMID:28238834 | chromium atom | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of NRAP mRNA] | CTD | PMID:16940432 | copper(II) sulfate | increases expression | ISO | NRAP (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of NRAP mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of NRAP mRNA | CTD | PMID:27523638 | cyclophosphamide | increases expression | EXP | | 6480464 | Cyclophosphamide results in increased expression of NRAP mRNA | CTD | PMID:27281708 | daunorubicin | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | Daunorubicin results in decreased expression of NRAP mRNA | CTD | PMID:26537877 and PMID:28940058 | dexamethasone | increases expression | ISO | Nrap (Mus musculus) | 6480464 | Dexamethasone results in increased expression of NRAP mRNA | CTD | PMID:22733784 | doxorubicin | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NRAP mRNA | CTD | PMID:26537877 more ... | endosulfan | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | Endosulfan results in decreased expression of NRAP mRNA | CTD | PMID:26615145 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of NRAP mRNA | CTD | PMID:29391264 | epoxiconazole | increases expression | ISO | Nrap (Mus musculus) | 6480464 | epoxiconazole results in increased expression of NRAP mRNA | CTD | PMID:35436446 | etoposide | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | Etoposide results in decreased expression of NRAP mRNA | CTD | PMID:29397400 | folic acid | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NRAP mRNA | CTD | PMID:22206623 | folpet | increases expression | ISO | Nrap (Mus musculus) | 6480464 | folpet results in increased expression of NRAP mRNA | CTD | PMID:31558096 | fonofos | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | Fonofos results in increased methylation of NRAP promoter | CTD | PMID:22847954 | genistein | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | Genistein results in decreased expression of NRAP mRNA | CTD | PMID:32186404 | graphite | increases expression | ISO | Nrap (Mus musculus) | 6480464 | Graphite results in increased expression of NRAP mRNA | CTD | PMID:27440207 | lipopolysaccharide | multiple interactions | ISO | NRAP (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NRAP mRNA] | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | NRAP (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of NRAP mRNA | CTD | PMID:35811015 | methapyrilene | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of NRAP exon | CTD | PMID:30157460 | mitoxantrone | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | Mitoxantrone results in decreased expression of NRAP mRNA | CTD | PMID:26537877 and PMID:28940058 | mono(2-ethylhexyl) phthalate | increases expression | ISO | Nrap (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of NRAP mRNA | CTD | PMID:22401849 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NRAP mRNA | CTD | PMID:36189433 | nicotinic acid | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of NRAP mRNA] | CTD | PMID:16940432 | parathion | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | Parathion results in increased methylation of NRAP promoter | CTD | PMID:22847954 | pioglitazone | multiple interactions | ISO | Nrap (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NRAP mRNA | CTD | PMID:27935865 | resveratrol | multiple interactions | ISO | NRAP (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of NRAP mRNA | CTD | PMID:23557933 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of NRAP mRNA | CTD | PMID:28374803 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | NRAP (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NRAP mRNA] | CTD | PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of NRAP mRNA | CTD | PMID:35811015 | sodium arsenite | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NRAP mRNA | CTD | PMID:29301061 | sodium dichromate | increases expression | ISO | Nrap (Mus musculus) | 6480464 | sodium bichromate results in increased expression of NRAP mRNA | CTD | PMID:31558096 | sunitinib | decreases expression | ISO | NRAP (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NRAP mRNA | CTD | PMID:31533062 | terbufos | increases methylation | ISO | NRAP (Homo sapiens) | 6480464 | terbufos results in increased methylation of NRAP promoter | CTD | PMID:22847954 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of NRAP mRNA | CTD | PMID:31150632 | titanium dioxide | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of NRAP mRNA | CTD | PMID:23557971 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of NRAP mRNA | CTD | PMID:33387578 | trimellitic anhydride | decreases expression | ISO | Nrap (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of NRAP mRNA | CTD | PMID:19042947 | |