Tom1l2 (target of myb1 like 2 membrane trafficking protein) - Rat Genome Database

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Gene: Tom1l2 (target of myb1 like 2 membrane trafficking protein) Rattus norvegicus
Analyze
Symbol: Tom1l2
Name: target of myb1 like 2 membrane trafficking protein
RGD ID: 1306728
Description: Predicted to enable clathrin binding activity and protein kinase binding activity. Predicted to be involved in negative regulation of mitotic nuclear division and signal transduction. Predicted to be active in endosome and membrane. Orthologous to human TOM1L2 (target of myb1 like 2 membrane trafficking protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360537; target of myb1-like 2; target of myb1-like 2 (chicken); TOM1-like protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,535,548 - 45,657,528 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1045,535,548 - 45,657,521 (-)EnsemblGRCr8
mRatBN7.21045,036,034 - 45,158,168 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,036,035 - 45,158,032 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1049,736,236 - 49,858,347 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,226,601 - 49,348,721 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01044,730,203 - 44,852,318 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,599,392 - 46,720,921 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,602,231 - 46,720,910 (-)Ensemblrn6Rnor6.0
Rnor_5.01046,354,436 - 46,475,909 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41046,503,435 - 46,612,883 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1044,306,563 - 44,415,406 (-)NCBICelera
RGSC_v3.11046,506,694 - 46,626,491 (-)NCBI
Cytogenetic Map10q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
endosome  (IBA)
membrane  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16412388   PMID:16479011   PMID:19056867   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Tom1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,535,548 - 45,657,528 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1045,535,548 - 45,657,521 (-)EnsemblGRCr8
mRatBN7.21045,036,034 - 45,158,168 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,036,035 - 45,158,032 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1049,736,236 - 49,858,347 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,226,601 - 49,348,721 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01044,730,203 - 44,852,318 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,599,392 - 46,720,921 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,602,231 - 46,720,910 (-)Ensemblrn6Rnor6.0
Rnor_5.01046,354,436 - 46,475,909 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41046,503,435 - 46,612,883 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1044,306,563 - 44,415,406 (-)NCBICelera
RGSC_v3.11046,506,694 - 46,626,491 (-)NCBI
Cytogenetic Map10q22NCBI
TOM1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381717,843,511 - 17,972,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1717,843,507 - 17,972,469 (-)Ensemblhg38GRCh38
GRCh371717,746,825 - 17,875,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361717,687,547 - 17,816,509 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341717,690,866 - 17,816,443NCBI
Celera1718,687,486 - 18,816,554 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1717,500,565 - 17,629,531 (-)NCBIHuRef
CHM1_11717,755,606 - 17,884,602 (-)NCBICHM1_1
T2T-CHM13v2.01717,790,194 - 17,919,077 (-)NCBIT2T-CHM13v2.0
Tom1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,114,622 - 60,243,766 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,117,540 - 60,243,731 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381160,226,714 - 60,352,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,226,714 - 60,352,905 (-)Ensemblmm10GRCm38
MGSCv371160,040,216 - 60,166,407 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361160,042,909 - 60,169,100 (-)NCBIMGSCv36mm8
Celera1166,594,747 - 66,648,912 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.81NCBI
Tom1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557793,480 - 153,437 (+)Ensembl
ChiLan1.0NW_00495557793,877 - 153,381 (+)NCBIChiLan1.0ChiLan1.0
TOM1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21952,360,236 - 52,487,365 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11757,072,480 - 57,199,566 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01733,324,590 - 33,451,688 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11738,272,362 - 38,399,178 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1738,272,362 - 38,399,178 (+)EnsemblpanPan2panpan1.1
TOM1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,535,069 - 41,654,609 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,535,005 - 41,650,717 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha541,674,100 - 41,793,147 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0541,641,433 - 41,760,562 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl541,641,398 - 41,760,561 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1541,609,151 - 41,728,170 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0541,556,560 - 41,675,573 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0541,748,457 - 41,867,500 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tom1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,311,707 - 61,430,403 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367411,436,814 - 1,555,633 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367411,436,845 - 1,555,533 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOM1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,652,189 - 60,729,259 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11260,652,153 - 60,729,257 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TOM1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11616,881,219 - 17,009,552 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1616,881,156 - 17,009,492 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660593,899,792 - 4,030,113 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tom1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248493,466,520 - 3,594,738 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248493,466,572 - 3,594,397 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Tom1l2
817 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:79
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000067866
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
11528631Bss117Bone structure and strength QTL 1176.414e-07femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)104544668145933445Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
11528628Bss116Bone structure and strength QTL 1166.464e-07femur morphology trait (VT:0000559)femur length (CMO:0000442)104467931246132467Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Mco13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,092,825 - 45,093,113 (+)MAPPERmRatBN7.2
Rnor_6.01046,655,710 - 46,655,997NCBIRnor6.0
Rnor_5.01046,410,570 - 46,410,857UniSTSRnor5.0
RGSC_v3.41046,546,806 - 46,547,094RGDRGSC3.4
RGSC_v3.41046,546,807 - 46,547,094UniSTSRGSC3.4
Celera1044,350,410 - 44,350,697UniSTS
RGSC_v3.11046,560,429 - 46,560,717RGD
Cytogenetic Map10q22UniSTS
RH143483  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,046,206 - 45,046,315 (+)MAPPERmRatBN7.2
Rnor_6.01046,609,566 - 46,609,674NCBIRnor6.0
Rnor_5.01046,364,515 - 46,364,623UniSTSRnor5.0
RGSC_v3.41046,500,362 - 46,500,470UniSTSRGSC3.4
Celera1044,303,490 - 44,303,598UniSTS
RH 3.4 Map10530.48UniSTS
Cytogenetic Map10q22UniSTS
BF389720  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81045,547,954 - 45,548,167 (+)Marker Load Pipeline
mRatBN7.21045,048,440 - 45,048,653 (+)MAPPERmRatBN7.2
Rnor_6.01046,611,800 - 46,612,012NCBIRnor6.0
Rnor_5.01046,366,749 - 46,366,961UniSTSRnor5.0
RGSC_v3.41046,502,596 - 46,502,808UniSTSRGSC3.4
Celera1044,305,724 - 44,305,936UniSTS
RH 3.4 Map10524.99UniSTS
Cytogenetic Map10q22UniSTS
RH135141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,038,745 - 45,038,925 (+)MAPPERmRatBN7.2
Rnor_6.01046,602,105 - 46,602,284NCBIRnor6.0
Rnor_5.01046,357,148 - 46,357,327UniSTSRnor5.0
RGSC_v3.41046,492,824 - 46,493,003UniSTSRGSC3.4
Celera1044,296,019 - 44,296,198UniSTS
RH 3.4 Map10526.39UniSTS
Cytogenetic Map10q22UniSTS
RH137494  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,132,782 - 45,132,973 (+)MAPPERmRatBN7.2
Rnor_6.01046,695,665 - 46,695,855NCBIRnor6.0
Rnor_5.01046,450,662 - 46,450,852UniSTSRnor5.0
RGSC_v3.41046,586,647 - 46,586,837UniSTSRGSC3.4
Celera1044,390,171 - 44,390,361UniSTS
Cytogenetic Map10q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC120835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000067866   ⟹   ENSRNOP00000061635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1045,049,280 - 45,158,032 (-)Ensembl
Rnor_6.0 Ensembl1046,612,639 - 46,720,910 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083093   ⟹   ENSRNOP00000075039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1045,549,382 - 45,657,521 (-)Ensembl
mRatBN7.2 Ensembl1045,049,868 - 45,158,020 (-)Ensembl
Rnor_6.0 Ensembl1046,602,231 - 46,720,907 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099670   ⟹   ENSRNOP00000079641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1045,049,280 - 45,071,202 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101854   ⟹   ENSRNOP00000096987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1045,535,548 - 45,657,521 (-)Ensembl
mRatBN7.2 Ensembl1045,036,035 - 45,158,020 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106889   ⟹   ENSRNOP00000081923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1045,535,548 - 45,589,787 (-)Ensembl
mRatBN7.2 Ensembl1045,036,036 - 45,158,013 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107932   ⟹   ENSRNOP00000080247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1045,535,548 - 45,657,521 (-)Ensembl
mRatBN7.2 Ensembl1045,036,035 - 45,158,020 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111837   ⟹   ENSRNOP00000096896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1045,535,548 - 45,657,521 (-)Ensembl
mRatBN7.2 Ensembl1045,036,035 - 45,158,020 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112948   ⟹   ENSRNOP00000086296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1045,535,548 - 45,657,521 (-)Ensembl
mRatBN7.2 Ensembl1045,036,035 - 45,158,020 (-)Ensembl
RefSeq Acc Id: NM_001399549   ⟹   NP_001386478
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,657,521 (-)NCBI
mRatBN7.21045,036,034 - 45,158,017 (-)NCBI
RefSeq Acc Id: NM_001399550   ⟹   NP_001386479
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,657,521 (-)NCBI
mRatBN7.21045,036,034 - 45,158,017 (-)NCBI
RefSeq Acc Id: XM_006246506   ⟹   XP_006246568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,657,528 (-)NCBI
mRatBN7.21045,036,034 - 45,158,043 (-)NCBI
Rnor_6.01046,599,392 - 46,720,921 (-)NCBI
Rnor_5.01046,354,436 - 46,475,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006246508   ⟹   XP_006246570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,657,528 (-)NCBI
mRatBN7.21045,036,034 - 45,158,042 (-)NCBI
Rnor_6.01046,599,392 - 46,720,921 (-)NCBI
Rnor_5.01046,354,436 - 46,475,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767835   ⟹   XP_008766057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,602,957 (-)NCBI
mRatBN7.21045,036,034 - 45,103,435 (-)NCBI
Rnor_6.01046,603,834 - 46,667,950 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086309   ⟹   XP_038942237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,657,508 (-)NCBI
mRatBN7.21045,036,034 - 45,158,108 (-)NCBI
RefSeq Acc Id: XM_063269332   ⟹   XP_063125402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,535,548 - 45,589,758 (-)NCBI
RefSeq Acc Id: XP_006246568   ⟸   XM_006246506
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZP70 (UniProtKB/TrEMBL),   A0A8I6AVU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246570   ⟸   XM_006246508
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A1X4 (UniProtKB/TrEMBL),   A0A8I6AVU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766057   ⟸   XM_008767835
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AVU7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061635   ⟸   ENSRNOT00000067866
Ensembl Acc Id: ENSRNOP00000075039   ⟸   ENSRNOT00000083093
RefSeq Acc Id: XP_038942237   ⟸   XM_039086309
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AVU7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080247   ⟸   ENSRNOT00000107932
Ensembl Acc Id: ENSRNOP00000096987   ⟸   ENSRNOT00000101854
Ensembl Acc Id: ENSRNOP00000096896   ⟸   ENSRNOT00000111837
Ensembl Acc Id: ENSRNOP00000081923   ⟸   ENSRNOT00000106889
Ensembl Acc Id: ENSRNOP00000079641   ⟸   ENSRNOT00000099670
Ensembl Acc Id: ENSRNOP00000086296   ⟸   ENSRNOT00000112948
RefSeq Acc Id: NP_001386478   ⟸   NM_001399549
- Peptide Label: isoform 1
- UniProtKB: A0A8I6AVU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386479   ⟸   NM_001399550
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZT36 (UniProtKB/TrEMBL),   A0A8I6AVU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125402   ⟸   XM_063269332
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AVU7 (UniProtKB/TrEMBL)
Protein Domains
GAT   VHS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9L2-F1-model_v2 AlphaFold A0A0G2K9L2 1-528 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697250
Promoter ID:EPDNEW_R7772
Type:multiple initiation site
Name:Tom1l2_1
Description:target of myb1 like 2 membrane trafficking protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01046,720,895 - 46,720,955EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306728 AgrOrtholog
BioCyc Gene G2FUF-24861 BioCyc
Ensembl Genes ENSRNOG00000003590 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083093.3 UniProtKB/TrEMBL
  ENSRNOT00000101854 ENTREZGENE
  ENSRNOT00000101854.2 UniProtKB/TrEMBL
  ENSRNOT00000106889 ENTREZGENE
  ENSRNOT00000106889.2 UniProtKB/TrEMBL
  ENSRNOT00000107932 ENTREZGENE
  ENSRNOT00000107932.2 UniProtKB/TrEMBL
  ENSRNOT00000111837.2 UniProtKB/TrEMBL
  ENSRNOT00000112948 ENTREZGENE
  ENSRNOT00000112948.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.160 UniProtKB/TrEMBL
  1.25.40.90 UniProtKB/TrEMBL
InterPro ENTH_VHS UniProtKB/TrEMBL
  GAT UniProtKB/TrEMBL
  GAT_sf UniProtKB/TrEMBL
  TOM1 UniProtKB/TrEMBL
  TOM1L2 UniProtKB/TrEMBL
  VHS_dom UniProtKB/TrEMBL
NCBI Gene 360537 ENTREZGENE
PANTHER PTHR13856:SF31 UniProtKB/TrEMBL
  VHS DOMAIN CONTAINING PROTEIN FAMILY UniProtKB/TrEMBL
Pfam GAT UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
PhenoGen Tom1l2 PhenoGen
PIRSF TOM1 UniProtKB/TrEMBL
PROSITE GAT UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003590 RatGTEx
SMART VHS UniProtKB/TrEMBL
Superfamily-SCOP GAT-like domain UniProtKB/TrEMBL
  SSF48464 UniProtKB/TrEMBL
UniProt A0A0G2K9L2_RAT UniProtKB/TrEMBL
  A0A8I5ZP70 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT36 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A1X4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AVU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLT5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-26 Tom1l2  target of myb1 like 2 membrane trafficking protein  Tom1l2  target of myb1-like 2 (chicken)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tom1l2  target of myb1-like 2 (chicken)   Tom1l2_predicted  target of myb1-like 2 (chicken) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tom1l2_predicted  target of myb1-like 2 (chicken) (predicted)      Symbol and Name status set to approved 70820 APPROVED