Adgrf2 (adhesion G protein-coupled receptor F2)

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Gene: Adgrf2 (adhesion G protein-coupled receptor F2) Rattus norvegicus

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Symbol:

Adgrf2

Name:

adhesion G protein-coupled receptor F2

RGD ID:

1306718

Description:

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Orthologous to human ADGRF2P (adhesion G protein-coupled receptor F2, pseudogene); INTERACTS WITH bisphenol A; lead diacetate; trichloroethene.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

adhesion G-protein coupled receptor F2; G protein-coupled receptor 111; G protein-coupled receptor 115; G-protein coupled receptor 111; G-protein coupled receptor PGR20; Gpr111; Gpr115; LOC301269; probable G-protein coupled receptor 111

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	25,735,607 - 25,745,962 (+)	NCBI		GRCr8
mRatBN7.2	9	18,238,389 - 18,248,745 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	18,219,714 - 18,269,038 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	20,898,943 - 20,948,284 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	20,917,673 - 20,950,386 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	19,771,781 - 19,810,350 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	13,960,770 - 13,973,241 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	13,936,316 - 13,968,349 (+)	NCBI
Celera	9	15,923,302 - 15,971,903 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

fulvestrant (ISO)

lead diacetate (EXP)

lipopolysaccharide (ISO)

resveratrol (ISO)

Theaflavin 3,3'-digallate (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IBA)

cell surface receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway (IEA)

Cellular Component

membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Adgrf2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	25,735,607 - 25,745,962 (+)	NCBI		GRCr8
mRatBN7.2	9	18,238,389 - 18,248,745 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	18,219,714 - 18,269,038 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	20,898,943 - 20,948,284 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	20,917,673 - 20,950,386 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	19,771,781 - 19,810,350 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	13,960,770 - 13,973,241 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	13,936,316 - 13,968,349 (+)	NCBI
Celera	9	15,923,302 - 15,971,903 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

ADGRF2P
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	47,656,472 - 47,697,794 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	47,673,420 - 47,693,719 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	47,624,208 - 47,665,530 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	47,732,285 - 47,766,296 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	47,732,181 - 47,758,379	NCBI
Celera	6	49,180,394 - 49,221,792 (+)	NCBI		Celera
Cytogenetic Map	6	p12.3	NCBI
HuRef	6	47,352,079 - 47,393,449 (+)	NCBI		HuRef
CHM1_1	6	47,627,133 - 47,668,488 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	47,498,118 - 47,539,580 (+)	NCBI		T2T-CHM13v2.0

Adgrf2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	43,004,919 - 43,054,646 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	43,007,021 - 43,053,070 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	42,694,028 - 42,743,753 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	42,696,130 - 42,742,179 (-)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	17	42,708,936 - 42,742,179 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	42,845,886 - 42,879,128 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	42,172,421 - 42,205,663 (-)	NCBI		MGSCv36	mm8
Celera	17	46,129,553 - 46,162,658 (-)	NCBI		Celera
Cytogenetic Map	17	B3	NCBI
cM Map	17	19.66	NCBI

Adgrf2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	12,095,601 - 12,126,710 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	12,104,938 - 12,126,649 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100991737
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	62,169,248 - 62,189,580 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	58,018,353 - 58,060,742 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	47,239,514 - 47,279,734 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	48,502,919 - 48,529,581 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	48,502,919 - 48,537,453 (+)	Ensembl	panpan1.1		panPan2

ADGRF2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	15,716,866 - 15,739,690 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	15,701,981 - 15,735,213 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	15,733,024 - 15,770,650 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	16,204,945 - 16,242,393 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	16,204,948 - 16,240,571 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	15,714,103 - 15,751,846 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	15,806,684 - 15,844,322 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	15,954,135 - 15,991,995 (+)	NCBI		UU_Cfam_GSD_1.0

Adgrf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	51,086,555 - 51,123,314 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936476	12,836,901 - 12,857,743 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADGRF4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	42,373,211 - 42,430,700 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	42,357,184 - 42,401,773 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	92,015,231 - 92,060,068 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADGRF2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	24,595,746 - 24,632,284 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666044	47,671,850 - 47,721,653 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adgrf2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	13,383,349 - 13,414,132 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Adgrf2
9 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	106
Count of miRNA genes:	86
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000033075
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
2303559	Gluco54	Glucose level QTL 54	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	1254084	46254084	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat
61450	Ciaa3	CIA Autoantibody QTL 3	6.5		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	9	7954720	22071169	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	1	37999212	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	1	43718459	Rat
1354650	Despr5	Despair related QTL 5	4.01	0.0017	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	9	1254084	46254084	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	40594091	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5109826	42921101	Rat
70226	Eae4	Experimental allergic encephalomyelitis QTL 4			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	9	1	25661317	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	1	37999212	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
724543	Cm20	Cardiac mass QTL 20	3.9		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	16961398	40594091	Rat
1600365	Mcs20	Mammary carcinoma susceptibility QTL 20	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	9	13533770	42791750	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	1	37999212	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	1	43718459	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	9	18	93	53	52	21	25	21	6	141	64	73	39	40	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001069077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_236958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033075 ⟹ ENSRNOP00000035606

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	18,219,714 - 18,269,038 (+)	Ensembl
Rnor_6.0 Ensembl	9	20,917,673 - 20,950,386 (+)	Ensembl

RefSeq Acc Id:

XM_017596752 ⟹ XP_017452241

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	25,735,607 - 25,745,962 (+)	NCBI
mRatBN7.2	9	18,238,389 - 18,248,745 (+)	NCBI
Rnor_6.0	9	20,917,433 - 20,948,284 (+)	NCBI

Sequence:

show sequence

TAAGGTGTGCCATGCAAATCAACCACAGAGAACGGGGATAATCTGAGCCTCCCACCTGCAGCCA
CATGGTAATGTCTCCATGTGGCAGGACACGGAGCCATCACCGCTGACCAGAGAGAGCTACTTAG
ACAGCTCTGAATACAGAGTCAGTTCTTACAGATGGATCTCGCCTGAAGAGACACGGTGCTATGA
AAACTTCAAATTGGAGACATTTTTTTCCGTTTCATTTATTTTTCCAGAAGCAAGAACGTCCTCC
ATGTGGAAGACCATGATTTCTGCCCGTTGGTTGTACTGCTTGGTCCTTCTTTTGGCTACGGAGT
CCTGTAGGCTATTCTGCCAGGCTGCCAGCAAAAGCAAGGAGAATGTGATGCCTAGGCCACATGA
TGTATGTGATGGTGTCTGTAAGAACAATGCCTCCCCCTGCTTTCAGTCTTGCCCTCCAAACAGT
GAGGGCAACATGAAATTTGCCTGTAAGGCCAAGAGATGGCACAAGGTCACGGAAACCTGCCACA
CTCTTAATGCCCACAGCATCTTTGAGGAAGATAAGGAATTATATTCAGTTCAATCATCTGAATC
AACTATACGTACACACATGTTTAATAGTGGACTAAAAACCATAACAGATACATTGATGGAAAAA
TGTCCAAAGGACTTGTCTTGTGTGATCAGAGGCATTGAGAAATCTCCTCGGATACCAGGGAACA
TTGCTGTGGTGGTACAGCTCTTACATAACATCTCAACGACTCTAACCAAAGGGGTGGATGAGGA
AAAGATGCAGAGCTACAGCGCCATGGCTAACCACATTCTTAACAGTAAAAGCATATCGAATTGG
ACCTTCATCCAAGACAGAAACAGCAGCTGTGTCTTGCTTCAATCAATCAATTCATTTGCAAGCA
ATCTATTCATGAAGGGACATCTCATCAACATATCACATGTCTTCATTCATACCTTGGGTACCGT
TGTGCCCAGAAACAGCCTTGGGAAGAATTTCACATTCTCAATGCGAGTTAATGATACAAGCGAT
AAAGTCACCGGGAGGATACTGCTTACTACTGAAGAGCTTCAGAAGGTGCCTTCCGCTTTCCAGG
TTATCAGCATTGCTTTCCCAACTCTTGGGGCCATCCTGGAGGCCAGCCTTCTGGAAAATATGAC
CGTGAATGGTCTCGTCCTGTCCGTCATTTTGCCTAAGGAGCTTAAGAACATCTCACTGATATTT
GAAAAGATCAGAAAATCTGGAGAGAGAAAGTCCCAGTGTGTGGGTTGGCACTCCCTGGAGAGCA
GATGGGACCGGAGAGCTTGTAAAATGATTCAAGAAAACTCCCGGCAAGCTATTTGCCGTTGTCA
GCCAAACAAGTTTTTTACCTCTTTCTCCATTCTAATGTCACCCAACACTGTGGAAAGCCCGGTT
CTAACTTATATCACATACATAGGTCTGGGCATTTCCATTTGTAGCTTGATCATCTGCCTGGCCA
TTGAGGCCTTAGTCTGGAGTCAAGTGACAAAGACAGAGATCTCATATTTACGTCACCTGTGCAT
CGCTAACATTGCAGTCACCTTGCTGATGGCTGATGTGTGGTTCATCGTGGCTTCTTTCCTCAGT
GGCCCAATCGTACACCACAACGGATGTGTGACTGCAACGTTTTTCGTTCACTTCTTTTACCTGT
CAGTGTTTTTCTGGATGCTTGCCAAGGCTCTCCTTATCCTGTACGGAATTCTCATCGTGTTCCA
CACCCTGCCCAAGTCGTGTCTGGTGGCCTCTCTGTTTACAGTGGGCTACGGGTGCCCTTTGGTC
ATCGCTGTCATCACACTTGCTGTTACAGAGCCTGGAAAAGGCTACCTCCGGCCTGAGGCTTGCT
GGCTTAACTGGGACATGACCAAGGCTCTCCTGGCCTTTGTAGTCCCAGCTCTGGCCATTGTTGT
AGTAAACCTGATTACAGTCACACTGGTTATCATCAAGACCCAAAGAGCTGCCGTTGGTAGTTCC
ATGTTCCAGGAAGTAAGAGCCATCGTAAGGATCTGTAAGAACATTGCTATCCTCACGCCACTGC
TGGGGCTGACCTGGGGATTTGGAATAGCCACAGTCGTTGCTGGTCACTCCCTGGCCTTCCACAT
CATCTTCTCCTTACTCAATGCACTACAGGGCTTCTTTATCCTGCTGTTTGGAACAATCCTGGAT
CCAAAGATAAGAGAAGCCTTAAAGAGTCGAGTAACATCTGTTAAATGGATTTCCAGAGTATCAG
AGGACCTTTCTTCTGAATTCTCTTGTCATCCTACCAAAGGGCCAAGCTAACAAACCAGGATGCA
CCCCTCACACGGATGGTTGCTCATTCCTGGAACGGCAGTGCCCAAGGAAGCATGCACTTAATTC
CTGTCCTCTTGCCTCTGGGCACTTTGAAGGAAACCTCCCACATTGCAGCGCCGGTGGAGGCAGG
GGTGACATGCGCAAAGCACGAAGGCCTCTCTGTCTAAGCTCTTCCGTGTTTCTACTCATGCCTT
GCCCACCAACTGCAAATCTATATAGGACACAGTAAGCATCCTCGAGGGACAAGAAGACAAAGTG
GGACACAGCAACGGGGTCTTTCTCACAGGTGCCTCCGTCATTACACTCCTGGGCCAAACTGATC
TTCAGGGCGAGAGCTCTGCTTATCCCAGCAAAGGTGGCCTAGGATGCCCTGTGTGGGATTCTAA
AGAGGCTCCCAAAGAAGAGTCGCCAGCAGTTGCACTGACTCTAAGCAGCTCACCACTGGTCAGG
GGCAATTGTTTAGATGGTCAGCCTGGCTCGGACGTGGATGCAGCTCCTTTGATGGTGAACCAAG
GGAAAACCATAGCGTGTTTGAATTGGACATGATGCCTGTTTTAAGATGAGACGGAAGCCTGGGA
ACTGTGAACCACAGCTTTGCTGTCCTCAGCCAACTCTATTGGCTTTCAGCGCTCCCTTTTCTCT
CCCAGAGCACAGGGCCTCTGAGGGGTTTTCTGCTTCGGTTTTCAGACGTGGGAGGTTTCTGAAA
CATGGATGTGGGAGAGAAAACATTGTATTTCAAGCACAGTGCTGTTGTTCATTTTCCTAGCTGT
ATGTAAACACATTCCGCATCCAAAGCAGATGTCACCCAACAGAGAACAATGTTGGCGGGGCGGC
AGCGGGGGGTGGGGGTAGAAGCCCTCCCCAAAGCAAGCACACAGGCAGCTGCCCCTGAAGGAAA
GCAGGGGTTAAGGATAAAGGGGCACAGATATATGGTCCAAGCCATCCCATGGAAGCCAGTATTA
TCGATGTTCTGTTACGGATGGGAGGCTAGGCATGGTGGGCACCATTAGAATCCCAGCACTTGGG
ATGCAGGGACTCAGAGAGCTGCTTTGAGTTCGAGGCCACCTTGGTTTAGTTTACATGGTTAGTG
GTAAATGGTCCAAAGCTAAAGGGTAAGATCTTGTTTAATAAAGCAACATGAAATAAATAAAAAC
AAAACAAACAAAACTGTGTGCTCAGACGCGCACACACACACACAC

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Protein Sequences


Protein RefSeqs	XP_017452241	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D4A3T6	(Get FASTA)	NCBI Sequence Viewer
	EDM18683	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000035606.6

RefSeq Acc Id:

XP_017452241 ⟸ XM_017596752

- UniProtKB:

A6JJ49 (UniProtKB/TrEMBL)

- Sequence:

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MWQDTEPSPLTRESYLDSSEYRVSSYRWISPEETRCYENFKLETFFSVSFIFPEARTSSMWKTM
ISARWLYCLVLLLATESCRLFCQAASKSKENVMPRPHDVCDGVCKNNASPCFQSCPPNSEGNMK
FACKAKRWHKVTETCHTLNAHSIFEEDKELYSVQSSESTIRTHMFNSGLKTITDTLMEKCPKDL
SCVIRGIEKSPRIPGNIAVVVQLLHNISTTLTKGVDEEKMQSYSAMANHILNSKSISNWTFIQD
RNSSCVLLQSINSFASNLFMKGHLINISHVFIHTLGTVVPRNSLGKNFTFSMRVNDTSDKVTGR
ILLTTEELQKVPSAFQVISIAFPTLGAILEASLLENMTVNGLVLSVILPKELKNISLIFEKIRK
SGERKSQCVGWHSLESRWDRRACKMIQENSRQAICRCQPNKFFTSFSILMSPNTVESPVLTYIT
YIGLGISICSLIICLAIEALVWSQVTKTEISYLRHLCIANIAVTLLMADVWFIVASFLSGPIVH
HNGCVTATFFVHFFYLSVFFWMLAKALLILYGILIVFHTLPKSCLVASLFTVGYGCPLVIAVIT
LAVTEPGKGYLRPEACWLNWDMTKALLAFVVPALAIVVVNLITVTLVIIKTQRAAVGSSMFQEV
RAIVRICKNIAILTPLLGLTWGFGIATVVAGHSLAFHIIFSLLNALQGFFILLFGTILDPKIRE
ALKSRVTSVKWISRVSEDLSSEFSCHPTKGPS

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Ensembl Acc Id:

ENSRNOP00000035606 ⟸ ENSRNOT00000033075

Protein Domains

G-protein coupled receptors family 2 profile GAIN-B

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A3T6-F1-model_v2	AlphaFold	D4A3T6	1-638	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306718	AgrOrtholog
BioCyc Gene	G2FUF-28095	BioCyc
Ensembl Genes	ENSRNOG00000025603	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033075.6	UniProtKB/TrEMBL
Gene3D-CATH	2.60.220.50	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Adhesion_GPCR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GAIN_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_2-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_2_Ig-hepta-like_rcpt	UniProtKB/TrEMBL
	GPCR_2_secretin-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	301269	ENTREZGENE
PANTHER	ADHESION G-PROTEIN COUPLED RECEPTOR F2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR45813	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Adgrf2	PhenoGen
PRINTS	GPCRSECRETIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGHEPTARCPTR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F2_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000025603	RatGTEx
SMART	GPS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0H2UHU8_RAT	UniProtKB/TrEMBL
	A6JJ49	ENTREZGENE, UniProtKB/TrEMBL
	AGRF2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-03-16	Adgrf2	adhesion G protein-coupled receptor F2	Gpr111	G protein-coupled receptor 111	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Gpr111	G protein-coupled receptor 111	Gpr115_predicted	G protein-coupled receptor 115 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Gpr115_predicted	G protein-coupled receptor 115 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar