Adamts7 (ADAM metallopeptidase with thrombospondin type 1 motif, 7) - Rat Genome Database

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Gene: Adamts7 (ADAM metallopeptidase with thrombospondin type 1 motif, 7) Rattus norvegicus
Analyze
Symbol: Adamts7
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 7
RGD ID: 1306713
Description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; collagen fibril organization; and skeletal system development. Predicted to be located in cell surface. Predicted to be active in extracellular matrix. Orthologous to human ADAMTS7 (ADAM metallopeptidase with thrombospondin type 1 motif 7); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 7; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7; ADAMTS7B; COMPase; LOC315879
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8899,584,529 - 99,624,132 (+)NCBIGRCr8
mRatBN7.2890,704,727 - 90,744,333 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl890,704,727 - 90,744,328 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx896,384,440 - 96,424,297 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0894,583,859 - 94,623,721 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0892,431,927 - 92,471,554 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0897,535,777 - 97,575,661 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl897,535,777 - 97,575,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0897,035,311 - 97,074,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4895,068,562 - 95,108,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1895,090,544 - 95,127,512 (+)NCBI
Celera890,247,876 - 90,286,673 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Adamts7RatBloom syndrome  ISOADAMTS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:28492532
Adamts7Ratcolorectal cancer  ISOADAMTS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532
Adamts7RatCoronary Disease  ISOADAMTS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Three Vessel Coronary DiseaseClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Adamts7Ratcoronary artery disease  ISOADAMTS7 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21378990
Adamts7Ratpolycystic ovary syndrome  ISOADAMTS7 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21411543

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Adamts7Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ADAMTS7 mRNA]CTDPMID:31150632
Adamts7Rat(1->4)-beta-D-glucan multiple interactionsISOAdamts7 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ADAMTS7 mRNACTDPMID:36331819
Adamts7Rat1,2-dimethylhydrazine increases expressionISOAdamts7 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of ADAMTS7 mRNACTDPMID:22206623
Adamts7Rat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of ADAMTS7 mRNACTDPMID:30723492
Adamts7Rat17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of ADAMTS7 mRNACTDPMID:17351261
Adamts7Rat17beta-estradiol multiple interactionsISOADAMTS7 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of ADAMTS7 mRNACTDPMID:30165855
Adamts7Rat17beta-estradiol increases expressionISOAdamts7 (Mus musculus)6480464Estradiol results in increased expression of ADAMTS7 mRNACTDPMID:39298647
Adamts7Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of ADAMTS7 mRNACTDPMID:32145629
Adamts7Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOAdamts7 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Adamts7Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOAdamts7 (Mus musculus)64804642 more ...CTDPMID:30294300
Adamts7Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOAdamts7 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Adamts7Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOAdamts7 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ADAMTS7 promoter]CTDPMID:19654925 and PMID:21889950
Adamts7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOAdamts7 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ADAMTS7 mRNACTDPMID:21570461 and PMID:26377647
Adamts7Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of ADAMTS7 mRNACTDPMID:21215274 and PMID:33387578
Adamts7Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of ADAMTS7 mRNACTDPMID:21346803
Adamts7Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of ADAMTS7 mRNACTDPMID:21346803
Adamts7Rat3,3',4,4',5-pentachlorobiphenyl increases expressionISOADAMTS7 (Homo sapiens)64804643 more ...CTDPMID:35618242
Adamts7Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOAdamts7 (Mus musculus)6480464tetrabromobisphenol A results in decreased expression of ADAMTS7 mRNACTDPMID:25172293
Adamts7Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2 and 6-dinitrotoluene affects the expression of ADAMTS7 mRNACTDPMID:21346803
Adamts7Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of ADAMTS7 mRNACTDPMID:24780913 and PMID:30047161

1 to 20 of 83 rows

Biological Process
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Adamts7Ratcellular response to BMP stimulus involved_inISOADAMTS7 (Homo sapiens)1624291 PMID:22247065RGDPMID:22247065
Adamts7Ratcellular response to interleukin-1 involved_inISOADAMTS7 (Homo sapiens)1624291 PMID:18485748RGDPMID:18485748
Adamts7Ratcellular response to tumor necrosis factor involved_inISOADAMTS7 (Homo sapiens)1624291 PMID:18485748RGDPMID:18485748
Adamts7Ratchondrocyte differentiation involved_inISOAdamts7 (Mus musculus)1624291MGI:2146046 PMID:29618652RGDPMID:29618652
Adamts7Ratcollagen fibril organization involved_inISOAdamts7 (Mus musculus)1624291MGI:1347346 more ...RGDPMID:29618652
Adamts7Ratextracellular matrix organization involved_inIEAInterPro:IPR0132731600115GO_REF:0000002InterProGO_REF:0000002
Adamts7Ratextracellular matrix organization involved_inIBAFB:FBgn0003137 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Adamts7Ratnegative regulation of chondrocyte differentiation involved_inISOADAMTS7 (Homo sapiens)1624291 PMID:22247065RGDPMID:22247065
Adamts7Ratossification involved_inISOAdamts7 (Mus musculus)1624291MGI:2146046 PMID:29618652RGDPMID:29618652
Adamts7Ratossification involved in bone maturation involved_inISOAdamts7 (Mus musculus)1624291MGI:1347346 more ...RGDPMID:29618652
Adamts7Ratproteoglycan metabolic process involved_inISOAdamts7 (Mus musculus)1624291MGI:2146046 PMID:29618652RGDPMID:29618652
Adamts7Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Adamts7Ratproteolysis acts_upstream_of_or_withinISOAdamts7 (Mus musculus)1624291 PMID:15192113RGDPMID:15192113
Adamts7Ratproteolysis involved_inIEAInterPro:IPR0015901600115GO_REF:0000002InterProGO_REF:0000002
Adamts7Ratproteolysis involved_inIBAMGI:1339949 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Adamts7Ratproteolysis involved in protein catabolic process involved_inISOADAMTS7 (Homo sapiens)1624291 PMID:18485748RGDPMID:18485748
1 to 16 of 16 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Adamts7Ratcell surface located_inISOAdamts7 (Mus musculus)1624291 PMID:15192113RGDPMID:15192113
Adamts7Ratextracellular matrix is_active_inIBAFB:FBgn0003137 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Adamts7Ratextracellular matrix located_inISOAdamts7 (Mus musculus)1624291 PMID:15192113RGDPMID:15192113
Adamts7Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15192113   PMID:16585064   PMID:18485748   PMID:19168437   PMID:21869572   PMID:22247065   PMID:22995515   PMID:23928557   PMID:24006456   PMID:25921940   PMID:26938210   PMID:31638262  
PMID:31894258  



Adamts7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8899,584,529 - 99,624,132 (+)NCBIGRCr8
mRatBN7.2890,704,727 - 90,744,333 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl890,704,727 - 90,744,328 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx896,384,440 - 96,424,297 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0894,583,859 - 94,623,721 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0892,431,927 - 92,471,554 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0897,535,777 - 97,575,661 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl897,535,777 - 97,575,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0897,035,311 - 97,074,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4895,068,562 - 95,108,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1895,090,544 - 95,127,512 (+)NCBI
Celera890,247,876 - 90,286,673 (+)NCBICelera
Cytogenetic Map8q31NCBI
ADAMTS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381578,759,206 - 78,811,464 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1578,759,206 - 78,811,464 (-)EnsemblGRCh38hg38GRCh38
GRCh371579,051,548 - 79,103,806 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,838,600 - 76,890,828 (-)NCBINCBI36Build 36hg18NCBI36
Build 341576,838,604 - 76,890,828NCBI
Celera1555,988,022 - 56,040,507 (-)NCBICelera
Cytogenetic Map15q25.1NCBI
HuRef1555,809,947 - 55,863,180 (-)NCBIHuRef
CHM1_11579,169,979 - 79,222,005 (-)NCBICHM1_1
T2T-CHM13v2.01576,622,631 - 76,675,136 (-)NCBIT2T-CHM13v2.0
Adamts7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39990,041,420 - 90,082,155 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl990,045,122 - 90,090,124 (+)EnsemblGRCm39 Ensembl
GRCm38990,162,904 - 90,200,102 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl990,163,069 - 90,208,071 (+)EnsemblGRCm38mm10GRCm38
MGSCv37990,057,816 - 90,094,940 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36989,961,138 - 89,997,904 (+)NCBIMGSCv36mm8
Celera989,777,163 - 89,814,434 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map947.46NCBI
Adamts7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955450529,999 - 577,621 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955450525,313 - 581,006 (+)NCBIChiLan1.0ChiLan1.0
LOC100976854
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21674,806,037 - 74,833,555 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11578,510,793 - 78,538,304 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01563,951,548 - 63,979,068 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11576,692,198 - 76,761,933 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1576,692,416 - 76,735,344 (-)Ensemblpanpan1.1panPan2
ADAMTS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1358,182,316 - 58,223,194 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl358,188,004 - 58,226,185 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha360,845,344 - 60,884,540 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0358,621,753 - 58,660,934 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl358,625,942 - 58,661,115 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1358,120,813 - 58,156,958 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0358,326,489 - 58,365,668 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0358,675,619 - 58,714,767 (+)NCBIUU_Cfam_GSD_1.0
Adamts7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640119,131,204 - 119,177,917 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647136,978,667 - 37,025,773 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647136,978,555 - 37,025,733 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl747,929,033 - 47,994,453 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1747,919,398 - 47,994,528 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2753,450,567 - 53,467,939 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666048136,431,118 - 136,445,421 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adamts7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248942,783,174 - 2,830,240 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248942,782,943 - 2,918,227 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Adamts7
284 total Variants

Predicted Target Of
Summary Value
Count of predictions:192
Count of miRNA genes:102
Interacting mature miRNAs:111
Transcripts:ENSRNOT00000037276, ENSRNOT00000068394
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 43 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat

1 to 10 of 43 rows
AA956863  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2890,744,103 - 90,744,213 (+)MAPPERmRatBN7.2
Rnor_6.0897,575,435 - 97,575,544NCBIRnor6.0
Rnor_5.0897,074,145 - 97,074,254UniSTSRnor5.0
RGSC_v3.4895,108,053 - 95,108,162UniSTSRGSC3.4
Celera890,286,453 - 90,286,562UniSTS
RH 3.4 Map81011.8UniSTS
Cytogenetic Map8q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000037276   ⟹   ENSRNOP00000037875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl890,706,829 - 90,744,328 (+)Ensembl
Rnor_6.0 Ensembl897,537,968 - 97,575,636 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000068394   ⟹   ENSRNOP00000060069
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl890,704,727 - 90,744,324 (+)Ensembl
Rnor_6.0 Ensembl897,535,777 - 97,575,655 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118446   ⟹   ENSRNOP00000081488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl890,714,954 - 90,744,324 (+)Ensembl
RefSeq Acc Id: NM_001047101   ⟹   NP_001040566
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,584,529 - 99,624,132 (+)NCBI
mRatBN7.2890,704,727 - 90,744,333 (+)NCBI
Rnor_6.0897,535,777 - 97,575,655 (+)NCBI
Rnor_5.0897,035,311 - 97,074,371 (+)NCBI
RGSC_v3.4895,068,562 - 95,108,273 (+)RGD
Celera890,247,876 - 90,286,673 (+)RGD
Sequence:
RefSeq Acc Id: NM_001393839   ⟹   NP_001380768
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,586,631 - 99,624,132 (+)NCBI
mRatBN7.2890,706,829 - 90,744,333 (+)NCBI
RefSeq Acc Id: NM_001393840   ⟹   NP_001380769
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,586,631 - 99,624,132 (+)NCBI
mRatBN7.2890,706,829 - 90,744,333 (+)NCBI
RefSeq Acc Id: XM_006243524   ⟹   XP_006243586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,586,648 - 99,624,127 (+)NCBI
mRatBN7.2890,706,846 - 90,744,331 (+)NCBI
Rnor_6.0897,537,896 - 97,575,661 (+)NCBI
Rnor_5.0897,035,311 - 97,074,371 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243526   ⟹   XP_006243588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,586,648 - 99,624,127 (+)NCBI
mRatBN7.2890,706,846 - 90,744,331 (+)NCBI
Rnor_6.0897,537,896 - 97,575,661 (+)NCBI
Rnor_5.0897,035,311 - 97,074,371 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595671   ⟹   XP_017451160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8899,609,785 - 99,624,127 (+)NCBI
mRatBN7.2890,729,986 - 90,744,331 (+)NCBI
Rnor_6.0897,561,317 - 97,575,661 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001040566   ⟸   NM_001047101
- Peptide Label: isoform 1
- UniProtKB: A0A8I5ZSM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243586   ⟸   XM_006243524
- Peptide Label: isoform X1
- UniProtKB: A0A140TAF3 (UniProtKB/TrEMBL),   A0A8I5ZSM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243588   ⟸   XM_006243526
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZSM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451160   ⟸   XM_017595671
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000060069   ⟸   ENSRNOT00000068394
Disintegrin   Peptidase M12B   PLAC   TSP type-1

Name Modeler Protein Id AA Range Protein Structure
AF-Q1EHB3-F1-model_v2 AlphaFold Q1EHB3 1-1595 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696185
Promoter ID:EPDNEW_R6703
Type:multiple initiation site
Name:Adamts7_1
Description:ADAM metallopeptidase with thrombospondin type 1 motif, 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0897,538,016 - 97,538,076EPDNEW


1 to 40 of 47 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29566 BioCyc
Ensembl Genes ENSRNOG00000028036 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000037276 ENTREZGENE
  ENSRNOT00000068394 ENTREZGENE
  ENSRNOT00000068394.4 UniProtKB/Swiss-Prot
  ENSRNOT00000118446 ENTREZGENE
Gene3D-CATH 2.20.100.10 UniProtKB/Swiss-Prot
  2.60.120.830 UniProtKB/Swiss-Prot
  3.40.1620.60 UniProtKB/Swiss-Prot
  3.40.390.10 UniProtKB/Swiss-Prot
InterPro ADAM_CR_2 UniProtKB/Swiss-Prot
  ADAM_spacer1 UniProtKB/Swiss-Prot
  ADAMTS/ADAMTS-like UniProtKB/Swiss-Prot
  ADAMTS_ADAMTS-like UniProtKB/Swiss-Prot
  ADAMTS_CR_3 UniProtKB/Swiss-Prot
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot
  Peptidase_M12B UniProtKB/Swiss-Prot
  Peptidase_M12B_N UniProtKB/Swiss-Prot
  PLAC UniProtKB/Swiss-Prot
  TSP1_rpt UniProtKB/Swiss-Prot
  TSP1_rpt_sf UniProtKB/Swiss-Prot
KEGG Report rno:315879 UniProtKB/Swiss-Prot
NCBI Gene 315879 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 7 UniProtKB/Swiss-Prot
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/Swiss-Prot
Pfam ADAM_CR_2 UniProtKB/Swiss-Prot
  ADAM_CR_3 UniProtKB/Swiss-Prot
  ADAM_spacer1 UniProtKB/Swiss-Prot
  Pep_M12B_propep UniProtKB/Swiss-Prot
  Reprolysin UniProtKB/Swiss-Prot
  TSP1_ADAMTS UniProtKB/Swiss-Prot
  TSP_1 UniProtKB/Swiss-Prot
PhenoGen Adamts7 PhenoGen
PRINTS ADAMTSFAMILY UniProtKB/Swiss-Prot
PROSITE ADAM_MEPRO UniProtKB/Swiss-Prot
  PLAC UniProtKB/Swiss-Prot
  TSP1 UniProtKB/Swiss-Prot
  ZINC_PROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000028036 RatGTEx
SMART TSP1 UniProtKB/Swiss-Prot
1 to 40 of 47 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-18 Adamts7  ADAM metallopeptidase with thrombospondin type 1 motif, 7  Adamts7  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Adamts7  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7   Adamts7_predicted  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Adamts7_predicted  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 (predicted)    a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 (predicted)  Name updated 1299863 APPROVED
2005-01-12 Adamts7_predicted  a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED