Otub2 (OTU deubiquitinase, ubiquitin aldehyde binding 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Otub2 (OTU deubiquitinase, ubiquitin aldehyde binding 2) Rattus norvegicus
Analyze
Symbol: Otub2
Name: OTU deubiquitinase, ubiquitin aldehyde binding 2
RGD ID: 1306688
Description: Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to be involved in protein K11-linked deubiquitination; protein K48-linked deubiquitination; and protein K63-linked deubiquitination. Orthologous to human OTUB2 (OTU deubiquitinase, ubiquitin aldehyde binding 2); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314405; OTU domain, ubiquitin aldehyde binding 2; ubiquitin thioesterase OTUB2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,309,863 - 128,328,444 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6128,299,693 - 128,328,433 (+)EnsemblGRCr8
mRatBN7.26122,545,067 - 122,563,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,545,061 - 122,563,644 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6122,685,956 - 122,704,500 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,981,218 - 122,999,762 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,315,785 - 122,334,308 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,282,445 - 127,301,086 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,282,466 - 127,301,083 (+)Ensemblrn6Rnor6.0
Rnor_5.06136,503,029 - 136,521,616 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46127,679,755 - 127,698,318 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6120,025,797 - 120,044,342 (+)NCBICelera
RGSC_v3.16127,683,523 - 127,700,562 (+)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
casticin  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cypermethrin  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
folic acid  (ISO)
genistein  (ISO)
indometacin  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
lucanthone  (ISO)
metformin  (EXP)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodimethylamine  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15258613   PMID:18954305   PMID:21630459   PMID:23827681  


Genomics

Comparative Map Data
Otub2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,309,863 - 128,328,444 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6128,299,693 - 128,328,433 (+)EnsemblGRCr8
mRatBN7.26122,545,067 - 122,563,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,545,061 - 122,563,644 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6122,685,956 - 122,704,500 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,981,218 - 122,999,762 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,315,785 - 122,334,308 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,282,445 - 127,301,086 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,282,466 - 127,301,083 (+)Ensemblrn6Rnor6.0
Rnor_5.06136,503,029 - 136,521,616 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46127,679,755 - 127,698,318 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6120,025,797 - 120,044,342 (+)NCBICelera
RGSC_v3.16127,683,523 - 127,700,562 (+)NCBI
Cytogenetic Map6q32NCBI
OTUB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,026,340 - 94,048,930 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,026,340 - 94,048,930 (+)Ensemblhg38GRCh38
GRCh371494,492,686 - 94,515,276 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361493,562,477 - 93,585,029 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341493,562,476 - 93,585,027NCBI
Celera1474,546,470 - 74,569,021 (+)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1474,672,717 - 74,695,267 (+)NCBIHuRef
CHM1_11494,430,740 - 94,453,290 (+)NCBICHM1_1
T2T-CHM13v2.01488,253,655 - 88,276,245 (+)NCBIT2T-CHM13v2.0
Otub2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912103,343,244 - 103,372,609 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12103,354,941 - 103,372,609 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3812103,376,894 - 103,406,350 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12103,388,682 - 103,406,350 (+)Ensemblmm10GRCm38
MGSCv3712104,615,104 - 104,644,560 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612103,789,755 - 103,807,393 (+)NCBIMGSCv36mm8
Celera12104,593,576 - 104,623,107 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1252.92NCBI
Otub2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543816,079,860 - 16,096,686 (+)Ensembl
ChiLan1.0NW_00495543816,079,859 - 16,096,686 (+)NCBIChiLan1.0ChiLan1.0
OTUB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21595,183,769 - 95,206,322 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11494,400,278 - 94,424,970 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01474,658,535 - 74,681,084 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11493,991,913 - 94,015,157 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1493,991,913 - 94,015,157 (+)EnsemblpanPan2panpan1.1
OTUB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1863,094,378 - 63,114,028 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl863,095,238 - 63,118,441 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha862,671,269 - 62,687,875 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0863,365,723 - 63,384,970 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl863,366,089 - 63,384,501 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1863,043,280 - 63,059,899 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0863,094,695 - 63,111,321 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0863,424,888 - 63,441,523 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Otub2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864011,557,728 - 11,575,942 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367331,891,132 - 1,909,392 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367331,891,198 - 1,913,389 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTUB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7115,304,871 - 115,327,054 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17115,304,809 - 115,326,055 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27122,163,455 - 122,182,349 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OTUB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12471,783,388 - 71,806,721 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2471,795,047 - 71,803,732 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605359,023,310 - 59,046,089 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otub2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473410,384,777 - 10,404,716 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473410,384,877 - 10,404,333 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Otub2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17114,684,304 - 114,701,350 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Otub2
93 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:265
Count of miRNA genes:181
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000012124
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
D6Mgh3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26122,549,046 - 122,549,218 (+)MAPPERmRatBN7.2
Rnor_6.06127,286,494 - 127,286,661NCBIRnor6.0
Rnor_5.06136,507,025 - 136,507,192UniSTSRnor5.0
RGSC_v3.46127,683,728 - 127,683,895RGDRGSC3.4
RGSC_v3.46127,683,729 - 127,683,896UniSTSRGSC3.4
Celera6120,029,772 - 120,029,922UniSTS
RGSC_v3.16127,687,475 - 127,687,642RGD
RH 3.4 Map6839.1UniSTS
RH 3.4 Map6839.1RGD
SHRSP x BN Map677.5898UniSTS
SHRSP x BN Map677.5898RGD
Cytogenetic Map6q32UniSTS
RH133473  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26122,563,380 - 122,563,597 (+)MAPPERmRatBN7.2
Rnor_6.06127,300,815 - 127,301,031NCBIRnor6.0
Rnor_5.06136,521,346 - 136,521,562UniSTSRnor5.0
RGSC_v3.46127,698,050 - 127,698,266UniSTSRGSC3.4
Celera6120,044,074 - 120,044,290UniSTS
RH 3.4 Map6836.2UniSTS
Cytogenetic Map6q32UniSTS
BF395820  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26122,561,242 - 122,561,356 (+)MAPPERmRatBN7.2
Rnor_6.06127,298,677 - 127,298,790NCBIRnor6.0
Rnor_5.06136,519,208 - 136,519,321UniSTSRnor5.0
RGSC_v3.46127,695,912 - 127,696,025UniSTSRGSC3.4
Celera6120,041,936 - 120,042,049UniSTS
RH 3.4 Map6838.11UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 355 192 11 141 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012124   ⟹   ENSRNOP00000012124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,309,857 - 128,328,433 (+)Ensembl
mRatBN7.2 Ensembl6122,545,073 - 122,563,644 (+)Ensembl
Rnor_6.0 Ensembl6127,282,466 - 127,301,083 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113696   ⟹   ENSRNOP00000081107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,309,889 - 128,326,682 (+)Ensembl
mRatBN7.2 Ensembl6122,545,061 - 122,561,891 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156965   ⟹   ENSRNOP00000098856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,299,693 - 128,328,433 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158457   ⟹   ENSRNOP00000110582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,319,787 - 128,328,433 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160889   ⟹   ENSRNOP00000109026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,309,867 - 128,328,433 (+)Ensembl
RefSeq Acc Id: NM_001108053   ⟹   NP_001101523
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,309,863 - 128,328,444 (+)NCBI
mRatBN7.26122,545,067 - 122,563,657 (+)NCBI
Rnor_6.06127,282,466 - 127,301,083 (+)NCBI
Rnor_5.06136,503,029 - 136,521,616 (+)NCBI
RGSC_v3.46127,679,755 - 127,698,318 (+)RGD
Celera6120,025,797 - 120,044,342 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401354   ⟹   NP_001388283
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,309,863 - 128,328,444 (+)NCBI
mRatBN7.26122,545,067 - 122,563,657 (+)NCBI
RefSeq Acc Id: NM_001401355   ⟹   NP_001388284
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,309,863 - 128,328,444 (+)NCBI
mRatBN7.26122,545,067 - 122,563,657 (+)NCBI
RefSeq Acc Id: NP_001101523   ⟸   NM_001108053
- Peptide Label: isoform 3
- UniProtKB: A6JEM6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012124   ⟸   ENSRNOT00000012124
Ensembl Acc Id: ENSRNOP00000081107   ⟸   ENSRNOT00000113696
RefSeq Acc Id: NP_001388283   ⟸   NM_001401354
- Peptide Label: isoform 1
- UniProtKB: D3ZAR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388284   ⟸   NM_001401355
- Peptide Label: isoform 2
- UniProtKB: D3ZAR8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109026   ⟸   ENSRNOT00000160889
Ensembl Acc Id: ENSRNOP00000110582   ⟸   ENSRNOT00000158457
Ensembl Acc Id: ENSRNOP00000098856   ⟸   ENSRNOT00000156965
Protein Domains
OTU

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAR8-F1-model_v2 AlphaFold D3ZAR8 1-234 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694792
Promoter ID:EPDNEW_R5316
Type:initiation region
Name:Otub2_1
Description:OTU deubiquitinase, ubiquitin aldehyde binding 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06127,282,466 - 127,282,526EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306688 AgrOrtholog
BioCyc Gene G2FUF-36415 BioCyc
Ensembl Genes ENSRNOG00000009117 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012124.7 UniProtKB/TrEMBL
  ENSRNOT00000113696 ENTREZGENE
  ENSRNOT00000113696.2 UniProtKB/TrEMBL
  ENSRNOT00000156965 ENTREZGENE
  ENSRNOT00000156965.1 UniProtKB/TrEMBL
  ENSRNOT00000158457.1 UniProtKB/TrEMBL
  ENSRNOT00000160889.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1300.20 UniProtKB/TrEMBL
  3.30.200.60 UniProtKB/TrEMBL
InterPro OTU UniProtKB/TrEMBL
  Otubain UniProtKB/TrEMBL
  Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C65_otubain UniProtKB/TrEMBL
  Peptidase_C65_otubain_sub1 UniProtKB/TrEMBL
  Peptidase_C65_otubain_sub2 UniProtKB/TrEMBL
KEGG Report rno:314405 UniProtKB/TrEMBL
NCBI Gene 314405 ENTREZGENE
PANTHER PTHR12931 UniProtKB/TrEMBL
  PTHR12931:SF3 UniProtKB/TrEMBL
Pfam Peptidase_C65 UniProtKB/TrEMBL
PhenoGen Otub2 PhenoGen
PIRSF Ubiquitin_thioesterase_Otubain UniProtKB/TrEMBL
PROSITE OTU UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009117 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A8I6G7I8_RAT UniProtKB/TrEMBL
  A0ABK0L5A5_RAT UniProtKB/TrEMBL
  A0ABK0LE33_RAT UniProtKB/TrEMBL
  A0ABK0LVY3_RAT UniProtKB/TrEMBL
  A6JEM6 ENTREZGENE, UniProtKB/TrEMBL
  B5DEZ9_RAT UniProtKB/TrEMBL
  D3ZAR8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-13 Otub2  OTU deubiquitinase, ubiquitin aldehyde binding 2  Otub2  OTU domain, ubiquitin aldehyde binding 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Otub2  OTU domain, ubiquitin aldehyde binding 2   Otub2_predicted  OTU domain, ubiquitin aldehyde binding 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Otub2_predicted  OTU domain, ubiquitin aldehyde binding 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED