Smoc2 (SPARC related modular calcium binding 2)

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Gene: Smoc2 (SPARC related modular calcium binding 2) Rattus norvegicus

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Symbol:

Smoc2

Name:

SPARC related modular calcium binding 2

RGD ID:

1306681

Description:

Predicted to enable calcium ion binding activity; extracellular matrix binding activity; and heparin binding activity. Predicted to be involved in several processes, including positive regulation of endothelial cell chemotaxis; positive regulation of signal transduction; and positive regulation of vascular wound healing. Predicted to act upstream of or within positive regulation of cell-substrate adhesion. Predicted to be located in interstitial matrix. Predicted to be active in basement membrane and extracellular space. Orthologous to human SMOC2 (SPARC related modular calcium binding 2); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC292401; SPARC-related modular calcium-binding protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	63,935,627 - 64,064,952 (+)	NCBI		GRCr8
mRatBN7.2	1	55,262,472 - 55,391,804 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	55,262,530 - 55,391,693 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	60,133,640 - 60,262,572 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	68,790,717 - 68,919,413 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	62,043,596 - 62,172,525 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	56,242,289 - 56,374,106 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	56,242,346 - 56,374,120 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	57,434,118 - 57,565,436 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	53,165,792 - 53,295,145 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	53,168,675 - 53,298,175 (+)	NCBI
Celera	1	51,480,576 - 51,609,313 (+)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Dentin Dysplasia, Type 1 (ISO)

Experimental Liver Cirrhosis (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (EXP)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (EXP,ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3',5'-cyclic AMP (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3,7-dihydropurine-6-thione (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

cantharidin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

chrysene (ISO)

cisplatin (EXP)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

dexamethasone (EXP,ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethanol (ISO)

flurbiprofen (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

furan (EXP,ISO)

glafenine (EXP)

glycidol (EXP)

hydrogen peroxide (ISO)

indometacin (ISO)

inulin (ISO)

isoprenaline (ISO)

ketamine (EXP)

L-methionine (ISO)

maneb (ISO)

menadione (ISO)

mercaptopurine (EXP)

mercury dibromide (ISO)

methamphetamine (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

microcystin-LR (EXP,ISO)

N-nitrosodiethylamine (EXP,ISO)

N-nitrosodimethylamine (EXP)

oxaliplatin (EXP)

panobinostat (ISO)

paraquat (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenylephrine (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

purine-6-thiol (EXP)

pyridaben (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sodium fluoride (EXP)

sotorasib (ISO)

testosterone (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trametinib (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

extracellular matrix organization (IBA,ISO)

positive regulation of angiogenesis (ISO)

positive regulation of cell-substrate adhesion (ISO)

positive regulation of DNA biosynthetic process (ISO)

positive regulation of endothelial cell chemotaxis (ISO)

positive regulation of endothelial cell migration (ISO)

positive regulation of fibroblast growth factor receptor signaling pathway (ISO)

positive regulation of mitotic cell cycle (ISO)

positive regulation of vascular endothelial growth factor signaling pathway (ISO)

positive regulation of vascular wound healing (ISO)

Cellular Component

basement membrane (IBA,ISO)

cell periphery (ISO)

extracellular matrix (ISO)

extracellular space (IBA,ISO)

interstitial matrix (ISO)

Molecular Function

calcium ion binding (ISO)

extracellular matrix binding (IBA)

glycosaminoglycan binding (ISO)

heparin binding (IBA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12741954	PMID:16774925	PMID:18757743	PMID:36513634

Genomics

Comparative Map Data

Smoc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	63,935,627 - 64,064,952 (+)	NCBI		GRCr8
mRatBN7.2	1	55,262,472 - 55,391,804 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	55,262,530 - 55,391,693 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	60,133,640 - 60,262,572 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	68,790,717 - 68,919,413 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	62,043,596 - 62,172,525 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	56,242,289 - 56,374,106 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	56,242,346 - 56,374,120 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	57,434,118 - 57,565,436 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	53,165,792 - 53,295,145 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	53,168,675 - 53,298,175 (+)	NCBI
Celera	1	51,480,576 - 51,609,313 (+)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

SMOC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	168,441,184 - 168,667,992 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	168,441,151 - 168,673,445 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	168,841,864 - 169,068,672 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	168,584,880 - 168,810,596 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	168,660,586 - 168,886,303	NCBI
Celera	6	169,559,437 - 169,782,279 (+)	NCBI		Celera
Cytogenetic Map	6	q27	NCBI
HuRef	6	166,267,021 - 166,491,991 (+)	NCBI		HuRef
CHM1_1	6	169,103,759 - 169,328,184 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	169,784,308 - 170,014,051 (+)	NCBI		T2T-CHM13v2.0

Smoc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	14,499,768 - 14,625,052 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	14,499,768 - 14,625,052 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	14,279,490 - 14,404,790 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	14,279,506 - 14,404,790 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	14,416,513 - 14,541,797 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	14,016,132 - 14,141,361 (+)	NCBI		MGSCv36	mm8
Celera	17	15,080,624 - 15,205,897 (+)	NCBI		Celera
Cytogenetic Map	17	A2	NCBI
cM Map	17	8.95	NCBI

Smoc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	4,729,706 - 4,822,140 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	4,729,753 - 4,822,140 (-)	NCBI	ChiLan1.0	ChiLan1.0

SMOC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	188,680,006 - 188,916,951 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	186,561,388 - 186,795,664 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	166,430,178 - 166,664,577 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	171,366,929 - 171,588,320 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	171,366,929 - 171,589,084 (+)	Ensembl	panpan1.1		panPan2

SMOC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	55,826,354 - 55,986,053 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	55,825,666 - 55,986,052 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	56,617,795 - 56,777,591 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	56,009,740 - 56,168,234 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	56,009,366 - 56,168,233 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	55,906,584 - 56,065,183 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	55,753,833 - 55,912,398 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	56,380,993 - 56,539,474 (+)	NCBI		UU_Cfam_GSD_1.0

Smoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	150,202,183 - 150,342,912 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936489	17,454,270 - 17,594,901 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936489	17,454,274 - 17,594,894 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMOC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	1,193,167 - 1,332,694 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	1,193,163 - 1,332,739 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	2,133,877 - 2,217,364 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SMOC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	96,264,170 - 96,477,393 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	96,264,181 - 96,477,491 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	68,107,603 - 68,398,081 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Smoc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624850	4,510,598 - 4,661,056 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624850	4,510,700 - 4,658,579 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Smoc2
1009 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	455
Count of miRNA genes:	245
Interacting mature miRNAs:	301
Transcripts:	ENSRNOT00000019317
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	35239598	78430678	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	53895117	82174945	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	35239598	78430678	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	33449848	78449848	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
1357400	Bw62	Body weight QTL62	4.05		inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	1	22340647	67340647	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
1300167	Hrtrt2	Heart rate QTL 2	4.35		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	11481312	75088344	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	45803140	78430678	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	11835181	56835181	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	28879780	78430678	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	49361465	82174945	Rat
724520	Bp145	Blood pressure QTL 145	2.1	0.0024	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	20784828	65784828	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	34836858	79836858	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	50343510	99980958	Rat
738020	Pia8	Pristane induced arthritis QTL 8	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	1	65833076	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	33449848	78449848	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	10992065	55992065	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	53895117	82174945	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
634353	Rends2	Renal damage susceptibility QTL 2		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	1	19333571	56983283	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat

Markers in Region

D1Rat207

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	55,300,427 - 55,300,635 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	56,282,757 - 56,282,964	NCBI	Rnor6.0
Rnor_5.0	1	57,473,569 - 57,473,776	UniSTS	Rnor5.0
RGSC_v3.4	1	53,203,564 - 53,203,820	RGD	RGSC3.4
RGSC_v3.4	1	53,203,603 - 53,203,810	UniSTS	RGSC3.4
RGSC_v3.1	1	53,206,548 - 53,206,755	RGD
Celera	1	51,518,460 - 51,518,667	UniSTS
RH 3.4 Map	1	672.2	RGD
RH 3.4 Map	1	672.2	UniSTS
RH 2.0 Map	1	391.3	RGD
FHH x ACI Map	1	30.3199	RGD
Cytogenetic Map	1	q12	UniSTS

D17Jcs34

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	55,313,802 - 55,314,071 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	56,296,133 - 56,296,401	NCBI	Rnor6.0
Rnor_5.0	1	57,486,945 - 57,487,213	UniSTS	Rnor5.0
RGSC_v3.4	1	53,216,979 - 53,217,247	UniSTS	RGSC3.4
Celera	1	51,531,828 - 51,532,096	UniSTS
Cytogenetic Map	1	q12	UniSTS

RH130327

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	55,391,499 - 55,391,693 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	56,373,791 - 56,373,984	NCBI	Rnor6.0
Rnor_5.0	1	57,565,121 - 57,565,314	UniSTS	Rnor5.0
RGSC_v3.4	1	53,294,929 - 53,295,122	UniSTS	RGSC3.4
Celera	1	51,609,097 - 51,609,290	UniSTS
RH 3.4 Map	1	673.0	UniSTS
Cytogenetic Map	1	q12	UniSTS

BM387775

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	55,380,237 - 55,380,411 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	56,362,532 - 56,362,705	NCBI	Rnor6.0
Rnor_5.0	1	57,553,862 - 57,554,035	UniSTS	Rnor5.0
RGSC_v3.4	1	53,283,670 - 53,283,843	UniSTS	RGSC3.4
Celera	1	51,597,838 - 51,598,011	UniSTS
RH 3.4 Map	1	675.2	UniSTS
Cytogenetic Map	1	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006227958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019317 ⟹ ENSRNOP00000019317

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	55,262,530 - 55,391,693 (+)	Ensembl
Rnor_6.0 Ensembl	1	56,242,346 - 56,373,984 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079718 ⟹ ENSRNOP00000071488

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	55,306,478 - 55,391,693 (+)	Ensembl
Rnor_6.0 Ensembl	1	56,288,832 - 56,374,120 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109266 ⟹ ENSRNOP00000089764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	55,262,530 - 55,307,228 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113274 ⟹ ENSRNOP00000078071

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	55,306,478 - 55,386,655 (+)	Ensembl

RefSeq Acc Id:

NM_001106215 ⟹ NP_001099685

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	63,935,689 - 64,064,866 (+)	NCBI
mRatBN7.2	1	55,262,530 - 55,391,716 (+)	NCBI
Rnor_6.0	1	56,242,346 - 56,374,007 (+)	NCBI
Rnor_5.0	1	57,434,118 - 57,565,436 (+)	NCBI
RGSC_v3.4	1	53,165,792 - 53,295,145 (+)	RGD
Celera	1	51,480,576 - 51,609,313 (+)	RGD

Sequence:

show sequence

CCCGGCCGGAGCGCACGGAGGGGCCGTGCGGTCTCCACCAGAGGCGGTAGGACCGCAGAGCAGT
TCTTGACCCCTCGCTCTCGCGTTCGCACACCGGATCTTCGCCGAGTGCCTGGGTGCAGCGTGTG
GGGCGTCTGCCTCGCTTGGTCCCCTCCAGCGTCACCATGCTGCCGCCACAGCTGTGCTGGCTGC
CGCTGCTCGCTGCGTTGCTGCCGCCAGTGCCCGCGCAGAAGTTCTCGGCGCTCACGTTCTTGAG
AGTCGATCAAGACAAAGACAGAGACTGCAGCCTGGACTGCCCCAGCTCCCCTCAGAAGCCGCTC
TGCGCCTCAGATGGGAGGACCTTCCTGTCTAGATGTGAGTTCCAGCGGGCCAAGTGCAAAGATC
CCCAGCTGGAGATTGCCCACCGTGGGAACTGCAAAGATGTGTCCAGGTGTGTGGCTGAGAGGAA
GTACACCCAGGAGCAAGCCCGGAAGGAGTTCCAGCAAGTGTTCATCCCAGAATGCAACGACGAC
GGCACCTACAGTCAGGTCCAGTGTCACAGCTACACAGGATACTGTTGGTGTGTTACACCAAATG
GAAGGCCCATCAGTGGCACCGCTGTGGCCCACAAGACACCCAGGTGCCCCGGTTCAATAAATGA
AAAGCTGCCCCAGCGGGAAGGTGCCGGAAAAGCAGATGATGCTGCAGCCCCAGCATTGGAGACT
CAGCCCCAAGGAGATGAAGAAGATATTGCCTCACGCTACCCCACCCTCTGGACCGAGCAAGTTA
AGAGCCGGCAGAACAAGACCAATAAAAATTCAGCATCCTCCTGTGATCAGGAGCACCAGTCGGC
TCTTGAGGAAGCCAAGCAACCCAAGAATGACAATGTAGTGATCCCTGAGTGTGCACACGGCGGC
CTCTACAAGCCAGTGCAATGCCACCCATCCACTGGATACTGCTGGTGTGTGCTGGTAGACACTG
GGCGGCCCATTCCCGGGACCTCCACAAGGTATGAGCAGCCCAAATGTGATAACACAGCCCGAGC
TCACCCAGCGAAGGCCCGGGACCTGTACAAGAACAGGCCACTGCAGGGTTGTCCTGGTGCCAAA
AAGCACGAGTTTCTGACAAGTGTCCTGGATGCGCTCTCCACTGACATGGTCCACGCCGTCTCTG
ACCCCTCTTCCTCATCTGGCAGGCTGTCAGAGCCAGACCCCAGCCACACCCTGGAGGAGAGGGT
TGTGCATTGGTACTTCAAGCTGCTTGATAAGAACTCTAGCGGAGACATTGGCAAGAAGGAAATC
AAACCCTTTAAGAGGTTCCTGCGAAAGAAATCCAAGCCCAAAAAGTGCGTGAAGAAGTTTGTTG
AATACTGCGATATGAACAACGATAAGTCCATCACGGTGCAGGAGCTCATGGGCTGCTTGGGCGT
CACCAGAGAGGAGGGTAAAGCCAACACCAGGAAGCGTCACACCCCCAGAGGAAATGCCGAAAGT
ACTTCTTCGAATAGACAGCCCAGGAAACAAGGATGAATGGCTGACTACTCAAGACAGTTCCTAG
ACATGTGGGAATCTCCCTCACCAAAGAGCAATTAAAAACGAAAAACATATAGTATTTGCACTTT
GTACTTTAAATGTAAATTCACTTTGTAGAAATGAGATATTTAAACGGACTGTTGTGATCTGTGA
AAATGGAAGGCTGGCTTCGAGAAATTAATCACATACAATGTATGTGTCCTTGTTTGACCTTCGA
GATCTGTGCTGATGGAGTGGGTTTTTAAATGCATTTCAGCTTCACTTCCTCATCCCTCTGTGGA
GGGCCCGGCTTAGCCCTTTGCCCTATCCTCTGCCTGCAGTCTCCGTTGGCTTGCTCTTGGTCCT
CTTGATGCAAGCCAGAGCCTACGTGTCCTTAGGAGTTTTCAGTGGTCGCCTGTTTCATGAGGTT
TTGCTCTCTAGAGATGTCACTCAGGCACTAGCTCAGGCATAGCCTTAACTCCCAGTAGTGCCTG
TTTGAGGCTGTGCCGTCAGACTCTGTCAGAGGACTCCAGTTTTAGCTTCCACTTGAGCTTTAGC
TCTGCTCGAGTCAACCCTACTGTTAAATCTCCAGGGAGCTGAGTGGGCAAGCAGCCAGAGAGTC
CTCCTTCGGACAGCAAATCTAACTCTGGCTGACTGGCTCCATCCGACTGGCCCAGAAAGGATAC
AGTCTGCCTGCCTCACTTCTAAGTGTCCGGGCCATCCTGCTAGGGACCATTGGAAAGGAAAAAT
GCCTTCTGCAGAGATCATGGACCACATCCCGTGGAAGGCAGAGCTAGACTGGATCGCTCCAAGA
GTGCCGAGCAACGGGCAGCTGAGAATGTCACTTTGGTTCTGTGGGTGCCTGGGGGTTTGAGGGG
ATTCATCCAAGGCCCTTATGGGATGAAGGTTAGGAACTGGATGACCACACTGTGAGGGACGGGA
CTGGGCTGGGCTGTGTGCATAGTTGGCTGCCACTCTCTGACCTAGGTCGATCTGTACTCTCTGT
TCTCAAGGAACACTTGCAGATGGGGCAGAGTTGGGGCAACTCTTTCAGATTGGGGTTTAATGGA
AAACTGTTCATGGTCCCCAGCCTCTCAGTCTACGTCTGTGGCTGCATTGTGAACACACGTTGCG
GAAGGCCTTTGCTCGTTTGAACTGTGTATAGGCAAGAAGTGACCAGCTCACATCAACGCTGTCT
ACCAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006227958 ⟹ XP_006228020

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	63,935,627 - 64,064,952 (+)	NCBI
mRatBN7.2	1	55,262,472 - 55,391,804 (+)	NCBI
Rnor_6.0	1	56,242,289 - 56,374,106 (+)	NCBI
Rnor_5.0	1	57,434,118 - 57,565,436 (+)	NCBI

Sequence:

show sequence

CGGGAAACTAGGGTTATTTGACAGCAGCAGGGGCAGCCGAAGAAGAGTTCGTGGAGCCCCGGCC
GGAGCGCACGGAGGGGCCGTGCGGTCTCCACCAGAGGCGGTAGGACCGCAGAGCAGTTCTTGAC
CCCTCGCTCTCGCGTTCGCACACCGGATCTTCGCCGAGTGCCTGGGTGCAGCGTGTGGGGCGTC
TGCCTCGCTTGGTCCCCTCCAGCGTCACCATGCTGCCGCCACAGCTGTGCTGGCTGCCGCTGCT
CGCTGCGTTGCTGCCGCCAGTGCCCGCGCAGAAGTTCTCGGCGCTCACGTTCTTGAGAGTCGAT
CAAGACAAAGACAGAGACTGCAGCCTGGACTGCCCCAGCTCCCCTCAGAAGCCGCTCTGCGCCT
CAGATGGGAGGACCTTCCTGTCTAGATGTGAGTTCCAGCGGGCCAAGTGCAAAGATCCCCAGCT
GGAGATTGCCCACCGTGGGAACTGCAAAGATGTGTCCAGGTGTGTGGCTGAGAGGAAGTACACC
CAGGAGCAAGCCCGGAAGGAGTTCCAGCAAGTGTTCATCCCAGAATGCAACGACGACGGCACCT
ACAGTCAGGTCCAGTGTCACAGCTACACAGGATACTGTTGGTGTGTTACACCAAATGGAAGGCC
CATCAGTGGCACCGCTGTGGCCCACAAGACACCCAGGTGCCCCGGTTCAATAAATGAAAAGCTG
CCCCAGCGGGAAGGTGCCGGAAAAGCAGTCTCCTTGCAAATCTTTTCCGTTCTGAATTCAGATG
ATGCTGCAGCCCCAGCATTGGAGACTCAGCCCCAAGGAGATGAAGAAGATATTGCCTCACGCTA
CCCCACCCTCTGGACCGAGCAAGTTAAGAGCCGGCAGAACAAGACCAATAAAAATTCAGCATCC
TCCTGTGATCAGGAGCACCAGTCGGCTCTTGAGGAAGCCAAGCAACCCAAGAATGACAATGTAG
TGATCCCTGAGTGTGCACACGGCGGCCTCTACAAGCCAGTGCAATGCCACCCATCCACTGGATA
CTGCTGGTGTGTGCTGGTAGACACTGGGCGGCCCATTCCCGGGACCTCCACAAGGTATGAGCAG
CCCAAATGTGATAACACAGCCCGAGCTCACCCAGCGAAGGCCCGGGACCTGTACAAGAACAGGC
CACTGCAGGGTTGTCCTGGTGCCAAAAAGCACGAGTTTCTGACAAGTGTCCTGGATGCGCTCTC
CACTGACATGGTCCACGCCGTCTCTGACCCCTCTTCCTCATCTGGCAGGCTGTCAGAGCCAGAC
CCCAGCCACACCCTGGAGGAGAGGGTTGTGCATTGGTACTTCAAGCTGCTTGATAAGAACTCTA
GCGGAGACATTGGCAAGAAGGAAATCAAACCCTTTAAGAGGTTCCTGCGAAAGAAATCCAAGCC
CAAAAAGTGCGTGAAGAAGTTTGTTGAATACTGCGATATGAACAACGATAAGTCCATCACGGTG
CAGGAGCTCATGGGCTGCTTGGGCGTCACCAGAGAGGAGGGTAAAGCCAACACCAGGAAGCGTC
ACACCCCCAGAGGAAATGCCGAAAGTACTTCTTCGAATAGACAGCCCAGGAAACAAGGATGAAT
GGCTGACTACTCAAGACAGTTCCTAGACATGTGGGAATCTCCCTCACCAAAGAGCAATTAAAAA
CGAAAAACATATAGTATTTGCACTTTGTACTTTAAATGTAAATTCACTTTGTAGAAATGAGATA
TTTAAACGGACTGTTGTGATCTGTGAAAATGGAAGGCTGGCTTCGAGAAATTAATCACATACAA
TGTATGTGTCCTTGTTTGACCTTCGAGATCTGTGCTGATGGAGTGGGTTTTTAAATGCATTTCA
GCTTCACTTCCTCATCCCTCTGTGGAGGGCCCGGCTTAGCCCTTTGCCCTATCCTCTGCCTGCA
GTCTCCGTTGGCTTGCTCTTGGTCCTCTTGATGCAAGCCAGAGCCTACGTGTCCTTAGGAGTTT
TCAGTGGTCGCCTGTTTCATGAGGTTTTGCTCTCTAGAGATGTCACTCAGGCACTAGCTCAGGC
ATAGCCTTAACTCCCAGTAGTGCCTGTTTGAGGCTGTGCCGTCAGACTCTGTCAGAGGACTCCA
GTTTTAGCTTCCACTTGAGCTTTAGCTCTGCTCGAGTCAACCCTACTGTTAAATCTCCAGGGAG
CTGAGTGGGCAAGCAGCCAGAGAGTCCTCCTTCGGACAGCAAATCTAACTCTGGCTGACTGGCT
CCATCCGACTGGCCCAGAAAGGATACAGTCTGCCTGCCTCACTTCTAAGTGTCCGGGCCATCCT
GCTAGGGACCATTGGAAAGGAAAAATGCCTTCTGCAGAGATCATGGACCACATCCCGTGGAAGG
CAGAGCTAGACTGGATCGCTCCAAGAGTGCCGAGCAACGGGCAGCTGAGAATGTCACTTTGGTT
CTGTGGGTGCCTGGGGGTTTGAGGGGATTCATCCAAGGCCCTTATGGGATGAAGGTTAGGAACT
GGATGACCACACTGTGAGGGACGGGACTGGGCTGGGCTGTGTGCATAGTTGGCTGCCACTCTCT
GACCTAGGTCGATCTGTACTCTCTGTTCTCAAGGAACACTTGCAGATGGGGCAGAGTTGGGGCA
ACTCTTTCAGATTGGGGTTTAATGGAAAACTGTTCATGGTCCCCAGCCTCTCAGTCTACGTCTG
TGGCTGCATTGTGAACACACGTTGCGGAAGGCCTTTGCTCGTTTGAACTGTGTATAGGCAAGAA
GTGACCAGCTCACATCAACGCTGTCTACCAAAAAAAAAAAAAAAAAAAAAAAGTATGATCCTAA
CTGTTTTGGATAATCTTTTATATTGCTGAACTCTGAATTTAATCATTTTTATTAGATTAAAATA
TGCGATTAAACTGTGTTAGTCTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099685	(Get FASTA)	NCBI Sequence Viewer
	XP_006228020	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68953	(Get FASTA)	NCBI Sequence Viewer
	EDL99844	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019317.6
	ENSRNOP00000071488.1
	ENSRNOP00000078071.1
	ENSRNOP00000089764.1

RefSeq Acc Id:	NP_001099685 ⟸ NM_001106215
- Peptide Label:	precursor
- UniProtKB:	B5DF75 (UniProtKB/TrEMBL), A0A0G2K0K9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLPPQLCWLPLLAALLPPVPAQKFSALTFLRVDQDKDRDCSLDCPSSPQKPLCASDGRTFLSRC EFQRAKCKDPQLEIAHRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYT GYCWCVTPNGRPISGTAVAHKTPRCPGSINEKLPQREGAGKADDAAAPALETQPQGDEEDIASR YPTLWTEQVKSRQNKTNKNSASSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTG YCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKNRPLQGCPGAKKHEFLTSVLDAL STDMVHAVSDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSK PKKCVKKFVEYCDMNNDKSITVQELMGCLGVTREEGKANTRKRHTPRGNAESTSSNRQPRKQG hide sequence

RefSeq Acc Id:	XP_006228020 ⟸ XM_006227958
- Peptide Label:	isoform X1
- UniProtKB:	F7FPL2 (UniProtKB/TrEMBL), A0A0G2K0K9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLPPQLCWLPLLAALLPPVPAQKFSALTFLRVDQDKDRDCSLDCPSSPQKPLCASDGRTFLSRC EFQRAKCKDPQLEIAHRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYT GYCWCVTPNGRPISGTAVAHKTPRCPGSINEKLPQREGAGKAVSLQIFSVLNSDDAAAPALETQ PQGDEEDIASRYPTLWTEQVKSRQNKTNKNSASSCDQEHQSALEEAKQPKNDNVVIPECAHGGL YKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKNRPLQGCPGAKK HEFLTSVLDALSTDMVHAVSDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIK PFKRFLRKKSKPKKCVKKFVEYCDMNNDKSITVQELMGCLGVTREEGKANTRKRHTPRGNAEST SSNRQPRKQG hide sequence

Ensembl Acc Id:

ENSRNOP00000071488 ⟸ ENSRNOT00000079718

Ensembl Acc Id:

ENSRNOP00000019317 ⟸ ENSRNOT00000019317

Ensembl Acc Id:

ENSRNOP00000089764 ⟸ ENSRNOT00000109266

Ensembl Acc Id:

ENSRNOP00000078071 ⟸ ENSRNOT00000113274

Protein Domains

EF-hand Kazal-like Thyroglobulin type-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K0K9-F1-model_v2	AlphaFold	A0A0G2K0K9	1-457	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689636

Promoter ID:

EPDNEW_R161

Type:

multiple initiation site

Name:

Smoc2_1

Description:

SPARC related modular calcium binding 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	56,242,332 - 56,242,392	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306681	AgrOrtholog
BioCyc Gene	G2FUF-61337	BioCyc
Ensembl Genes	ENSRNOG00000014166	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019317.8	UniProtKB/TrEMBL
	ENSRNOT00000079718.2	UniProtKB/TrEMBL
	ENSRNOT00000109266.1	UniProtKB/TrEMBL
	ENSRNOT00000113274.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.60.30	UniProtKB/TrEMBL
	4.10.800.10	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
InterPro	Dev_reg/Prot_inhib	UniProtKB/TrEMBL
	EF-hand-like_dom	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_Ca-bd	UniProtKB/TrEMBL
	Kazal_dom_sf	UniProtKB/TrEMBL
	Prot_inh_Kazal	UniProtKB/TrEMBL
	SMOC2_EC	UniProtKB/TrEMBL
	SPARC/Testican_Ca-bd-dom	UniProtKB/TrEMBL
	Thyroglobulin_1	UniProtKB/TrEMBL
	Thyroglobulin_1_sf	UniProtKB/TrEMBL
KEGG Report	rno:292401	UniProtKB/TrEMBL
NCBI Gene	292401	ENTREZGENE
PANTHER	SECRETED MODULAR CALCIUM-BINDING PROTEIN	UniProtKB/TrEMBL
	SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2	UniProtKB/TrEMBL
Pfam	Kazal_2	UniProtKB/TrEMBL
	SPARC_Ca_bdg	UniProtKB/TrEMBL
	Thyroglob_assoc	UniProtKB/TrEMBL
	Thyroglobulin_1	UniProtKB/TrEMBL
PhenoGen	Smoc2	PhenoGen
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	KAZAL_2	UniProtKB/TrEMBL
	THYROGLOBULIN_1_1	UniProtKB/TrEMBL
	THYROGLOBULIN_1_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014166	RatGTEx
SMART	KAZAL	UniProtKB/TrEMBL
	SM00211	UniProtKB/TrEMBL
Superfamily-SCOP	SSF100895	UniProtKB/TrEMBL
	SSF47473	UniProtKB/TrEMBL
	Thyroglobulin_1	UniProtKB/TrEMBL
UniProt	A0A0G2K0K9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5Y6U6_RAT	UniProtKB/TrEMBL
	A0A8I6A7Z3_RAT	UniProtKB/TrEMBL
	B5DF75	ENTREZGENE, UniProtKB/TrEMBL
	F7FPL2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Smoc2	SPARC related modular calcium binding 2	Smoc2_predicted	SPARC related modular calcium binding 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Smoc2_predicted	SPARC related modular calcium binding 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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