Smoc2 (SPARC related modular calcium binding 2) - Rat Genome Database

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Gene: Smoc2 (SPARC related modular calcium binding 2) Rattus norvegicus
Analyze
Symbol: Smoc2
Name: SPARC related modular calcium binding 2
RGD ID: 1306681
Description: Predicted to enable calcium ion binding activity; extracellular matrix binding activity; and heparin binding activity. Predicted to be involved in several processes, including positive regulation of endothelial cell chemotaxis; positive regulation of signal transduction; and positive regulation of vascular wound healing. Predicted to act upstream of or within positive regulation of cell-substrate adhesion. Predicted to be located in interstitial matrix. Predicted to be active in basement membrane and extracellular space. Orthologous to human SMOC2 (SPARC related modular calcium binding 2); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC292401; SPARC-related modular calcium-binding protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,935,627 - 64,064,952 (+)NCBIGRCr8
mRatBN7.2155,262,472 - 55,391,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx160,133,640 - 60,262,572 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,790,717 - 68,919,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,043,596 - 62,172,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,242,289 - 56,374,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,242,346 - 56,374,120 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0157,434,118 - 57,565,436 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,165,792 - 53,295,145 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1153,168,675 - 53,298,175 (+)NCBI
Celera151,480,576 - 51,609,313 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Smoc2RatDentin Dysplasia, Type 1  ISOSMOC2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:22152679 more ...
Smoc2Ratschizophrenia  ISOSMOC2 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Smoc2RatDentin Dysplasia, Type 1  ISOSMOC2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Smoc2RatExperimental Liver Cirrhosis  ISOSMOC2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Smoc2RatDentin Dysplasia, Type 1  ISOSMOC2 (Homo sapiens)7240710 OMIM 

1 to 20 of 151 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Smoc2Rat(1->4)-beta-D-glucan multiple interactionsISOSmoc2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SMOC2 mRNACTDPMID:36331819
Smoc2Rat1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactionsEXP 64804642 more ...CTDPMID:19414516
Smoc2Rat1,2-dichloroethane decreases expressionISOSmoc2 (Mus musculus)6480464ethylene dichloride results in decreased expression of SMOC2 mRNACTDPMID:28960355
Smoc2Rat1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of SMOC2 mRNACTDPMID:27840820
Smoc2Rat1,2-dimethylhydrazine increases expressionISOSmoc2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of SMOC2 mRNACTDPMID:22206623
Smoc2Rat1,2-dimethylhydrazine multiple interactionsISOSmoc2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of SMOC2 mRNACTDPMID:22206623
Smoc2Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of SMOC2 mRNACTDPMID:25380136
Smoc2Rat17beta-estradiol increases expressionISOSMOC2 (Homo sapiens)6480464Estradiol results in increased expression of SMOC2 mRNACTDPMID:24758408 and PMID:31614463
Smoc2Rat17beta-estradiol increases expressionISOSmoc2 (Mus musculus)6480464Estradiol results in increased expression of SMOC2 mRNACTDPMID:39298647
Smoc2Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of SMOC2 mRNACTDPMID:32145629
Smoc2Rat17beta-estradiol multiple interactionsISOSMOC2 (Homo sapiens)6480464[Estradiol co-treated with Progesterone] results in increased expression of SMOC2 mRNA more ...CTDPMID:20660070 more ...
Smoc2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:27291303
Smoc2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOSmoc2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of SMOC2 mRNACTDPMID:19146932
Smoc2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSMOC2 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of SMOC2 mRNACTDPMID:36370075
Smoc2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of SMOC2 mRNACTDPMID:34747641
Smoc2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of SMOC2 mRNACTDPMID:32109520
Smoc2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSmoc2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SMOC2 mRNACTDPMID:26377647
Smoc2Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOSmoc2 (Mus musculus)64804642 more ...CTDPMID:38648751
Smoc2Rat3',5'-cyclic AMP multiple interactionsEXP 64804642 more ...CTDPMID:19414516
Smoc2Rat3,4-methylenedioxymethamphetamine increases expressionISOSmoc2 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SMOC2 mRNACTDPMID:20188158

1 to 20 of 151 rows

Biological Process
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Smoc2Ratextracellular matrix organization involved_inIBAMGI:1929878 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Smoc2Ratextracellular matrix organization acts_upstream_of_or_withinISOSmoc2 (Mus musculus)1624291 PMID:18757743RGDPMID:18757743
Smoc2Ratpositive regulation of angiogenesis involved_inISOSMOC2 (Homo sapiens)1624291UniProtKB:P09038 and PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of angiogenesis involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of cell-substrate adhesion acts_upstream_of_or_withinISOSmoc2 (Mus musculus)1624291 PMID:18757743RGDPMID:18757743
Smoc2Ratpositive regulation of DNA biosynthetic process involved_inISOSMOC2 (Homo sapiens)1624291UniProtKB:P09038 more ...RGDPMID:16774925
Smoc2Ratpositive regulation of DNA biosynthetic process involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of endothelial cell chemotaxis involved_inISOSMOC2 (Homo sapiens)1624291UniProtKB:P09038 and PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of endothelial cell chemotaxis involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of endothelial cell migration involved_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of endothelial cell migration involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of fibroblast growth factor receptor signaling pathway involved_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of fibroblast growth factor receptor signaling pathway involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of mitotic cell cycle involved_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of mitotic cell cycle involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of vascular endothelial growth factor signaling pathway involved_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of vascular endothelial growth factor signaling pathway involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratpositive regulation of vascular wound healing involved_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratpositive regulation of vascular wound healing involved_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 19 of 19 rows

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Smoc2Ratbasement membrane is_active_inIBAMGI:1929878 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Smoc2Ratbasement membrane located_inISOSmoc2 (Mus musculus)1624291 PMID:18757743RGDPMID:18757743
Smoc2Ratcell periphery located_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratcell periphery located_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratextracellular matrix located_inISOSmoc2 (Mus musculus)1624291 PMID:18757743RGDPMID:18757743
Smoc2Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Smoc2Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Smoc2Ratextracellular space located_inISOSMOC2 (Homo sapiens)1624291 PMID:16774925RGDPMID:16774925
Smoc2Ratextracellular space located_inIEAUniProtKB:Q9H3U7 and ensembl:ENSP000003486301600115GO_REF:0000107EnsemblGO_REF:0000107
Smoc2Ratextracellular space is_active_inIBAFB:FBgn0039054 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Smoc2Ratinterstitial matrix located_inISOSmoc2 (Mus musculus)1624291 PMID:18757743RGDPMID:18757743
1 to 11 of 11 rows

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:12741954   PMID:16774925   PMID:18757743   PMID:36513634  



Smoc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,935,627 - 64,064,952 (+)NCBIGRCr8
mRatBN7.2155,262,472 - 55,391,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx160,133,640 - 60,262,572 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,790,717 - 68,919,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,043,596 - 62,172,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,242,289 - 56,374,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,242,346 - 56,374,120 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0157,434,118 - 57,565,436 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,165,792 - 53,295,145 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1153,168,675 - 53,298,175 (+)NCBI
Celera151,480,576 - 51,609,313 (+)NCBICelera
Cytogenetic Map1q12NCBI
SMOC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386168,441,184 - 168,667,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6168,441,151 - 168,673,445 (+)EnsemblGRCh38hg38GRCh38
GRCh376168,841,864 - 169,068,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366168,584,880 - 168,810,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 346168,660,586 - 168,886,303NCBI
Celera6169,559,437 - 169,782,279 (+)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6166,267,021 - 166,491,991 (+)NCBIHuRef
CHM1_16169,103,759 - 169,328,184 (+)NCBICHM1_1
T2T-CHM13v2.06169,784,308 - 170,014,051 (+)NCBIT2T-CHM13v2.0
Smoc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391714,499,768 - 14,625,052 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1714,499,768 - 14,625,052 (+)EnsemblGRCm39 Ensembl
GRCm381714,279,490 - 14,404,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,279,506 - 14,404,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv371714,416,513 - 14,541,797 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361714,016,132 - 14,141,361 (+)NCBIMGSCv36mm8
Celera1715,080,624 - 15,205,897 (+)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
Smoc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554114,729,706 - 4,822,140 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554114,729,753 - 4,822,140 (-)NCBIChiLan1.0ChiLan1.0
SMOC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25188,680,006 - 188,916,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16186,561,388 - 186,795,664 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06166,430,178 - 166,664,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16171,366,929 - 171,588,320 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6171,366,929 - 171,589,084 (+)Ensemblpanpan1.1panPan2
SMOC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1155,826,354 - 55,986,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl155,825,666 - 55,986,052 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha156,617,795 - 56,777,591 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0156,009,740 - 56,168,234 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl156,009,366 - 56,168,233 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1155,906,584 - 56,065,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0155,753,833 - 55,912,398 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0156,380,993 - 56,539,474 (+)NCBIUU_Cfam_GSD_1.0
Smoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946150,202,183 - 150,342,912 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648917,454,270 - 17,594,901 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648917,454,274 - 17,594,894 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMOC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11,193,167 - 1,332,694 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.111,193,163 - 1,332,739 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.212,133,877 - 2,217,364 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMOC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11396,264,170 - 96,477,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1396,264,181 - 96,477,491 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604068,107,603 - 68,398,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smoc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248504,510,598 - 4,661,056 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248504,510,700 - 4,658,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Smoc2
1009 total Variants

Predicted Target Of
Summary Value
Count of predictions:455
Count of miRNA genes:245
Interacting mature miRNAs:301
Transcripts:ENSRNOT00000019317
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 47 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat

1 to 10 of 47 rows
D1Rat207  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8163,973,581 - 63,973,789 (+)Marker Load Pipeline
mRatBN7.2155,300,427 - 55,300,635 (+)MAPPERmRatBN7.2
Rnor_6.0156,282,757 - 56,282,964NCBIRnor6.0
Rnor_5.0157,473,569 - 57,473,776UniSTSRnor5.0
RGSC_v3.4153,203,564 - 53,203,820RGDRGSC3.4
RGSC_v3.4153,203,603 - 53,203,810UniSTSRGSC3.4
RGSC_v3.1153,206,548 - 53,206,755RGD
Celera151,518,460 - 51,518,667UniSTS
RH 3.4 Map1672.2UniSTS
RH 3.4 Map1672.2RGD
RH 2.0 Map1391.3RGD
FHH x ACI Map130.3199RGD
Cytogenetic Map1q12UniSTS
D17Jcs34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2155,313,802 - 55,314,071 (+)MAPPERmRatBN7.2
Rnor_6.0156,296,133 - 56,296,401NCBIRnor6.0
Rnor_5.0157,486,945 - 57,487,213UniSTSRnor5.0
RGSC_v3.4153,216,979 - 53,217,247UniSTSRGSC3.4
Celera151,531,828 - 51,532,096UniSTS
Cytogenetic Map1q12UniSTS
RH130327  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2155,391,499 - 55,391,693 (+)MAPPERmRatBN7.2
Rnor_6.0156,373,791 - 56,373,984NCBIRnor6.0
Rnor_5.0157,565,121 - 57,565,314UniSTSRnor5.0
RGSC_v3.4153,294,929 - 53,295,122UniSTSRGSC3.4
Celera151,609,097 - 51,609,290UniSTS
RH 3.4 Map1673.0UniSTS
Cytogenetic Map1q12UniSTS
BM387775  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2155,380,237 - 55,380,411 (+)MAPPERmRatBN7.2
Rnor_6.0156,362,532 - 56,362,705NCBIRnor6.0
Rnor_5.0157,553,862 - 57,554,035UniSTSRnor5.0
RGSC_v3.4153,283,670 - 53,283,843UniSTSRGSC3.4
Celera151,597,838 - 51,598,011UniSTS
RH 3.4 Map1675.2UniSTS
Cytogenetic Map1q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000019317   ⟹   ENSRNOP00000019317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)Ensembl
Rnor_6.0 Ensembl156,242,346 - 56,373,984 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079718   ⟹   ENSRNOP00000071488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,306,478 - 55,391,693 (+)Ensembl
Rnor_6.0 Ensembl156,288,832 - 56,374,120 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109266   ⟹   ENSRNOP00000089764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,262,530 - 55,307,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113274   ⟹   ENSRNOP00000078071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,306,478 - 55,386,655 (+)Ensembl
RefSeq Acc Id: NM_001106215   ⟹   NP_001099685
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,935,689 - 64,064,866 (+)NCBI
mRatBN7.2155,262,530 - 55,391,716 (+)NCBI
Rnor_6.0156,242,346 - 56,374,007 (+)NCBI
Rnor_5.0157,434,118 - 57,565,436 (+)NCBI
RGSC_v3.4153,165,792 - 53,295,145 (+)RGD
Celera151,480,576 - 51,609,313 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227958   ⟹   XP_006228020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,935,627 - 64,064,952 (+)NCBI
mRatBN7.2155,262,472 - 55,391,804 (+)NCBI
Rnor_6.0156,242,289 - 56,374,106 (+)NCBI
Rnor_5.0157,434,118 - 57,565,436 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001099685 (Get FASTA)   NCBI Sequence Viewer  
  XP_006228020 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68953 (Get FASTA)   NCBI Sequence Viewer  
  EDL99844 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019317
  ENSRNOP00000019317.6
  ENSRNOP00000071488.1
  ENSRNOP00000078071.1
  ENSRNOP00000089764.1
1 to 9 of 9 rows
RefSeq Acc Id: NP_001099685   ⟸   NM_001106215
- Peptide Label: precursor
- UniProtKB: B5DF75 (UniProtKB/TrEMBL),   A0A0G2K0K9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228020   ⟸   XM_006227958
- Peptide Label: isoform X1
- UniProtKB: F7FPL2 (UniProtKB/TrEMBL),   A0A0G2K0K9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071488   ⟸   ENSRNOT00000079718
Ensembl Acc Id: ENSRNOP00000019317   ⟸   ENSRNOT00000019317
Ensembl Acc Id: ENSRNOP00000089764   ⟸   ENSRNOT00000109266
EF-hand   Kazal-like   Thyroglobulin type-1

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0K9-F1-model_v2 AlphaFold A0A0G2K0K9 1-457 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13689636
Promoter ID:EPDNEW_R161
Type:multiple initiation site
Name:Smoc2_1
Description:SPARC related modular calcium binding 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0156,242,332 - 56,242,392EPDNEW


1 to 40 of 45 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-61337 BioCyc
Ensembl Genes ENSRNOG00000014166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019317 ENTREZGENE
  ENSRNOT00000019317.8 UniProtKB/TrEMBL
  ENSRNOT00000079718.2 UniProtKB/TrEMBL
  ENSRNOT00000109266.1 UniProtKB/TrEMBL
  ENSRNOT00000113274.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Dev_reg/Prot_inhib UniProtKB/TrEMBL
  EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  Prot_inh_Kazal UniProtKB/TrEMBL
  SMOC2_EC UniProtKB/TrEMBL
  SPARC/Testican_Ca-bd-dom UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
KEGG Report rno:292401 UniProtKB/TrEMBL
NCBI Gene 292401 ENTREZGENE
PANTHER SECRETED MODULAR CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
  SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/TrEMBL
  SPARC_Ca_bdg UniProtKB/TrEMBL
  Thyroglob_assoc UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PhenoGen Smoc2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014166 RatGTEx
SMART KAZAL UniProtKB/TrEMBL
  SM00211 UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
1 to 40 of 45 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Smoc2  SPARC related modular calcium binding 2   Smoc2_predicted  SPARC related modular calcium binding 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Smoc2_predicted  SPARC related modular calcium binding 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED