Smoc2 (SPARC related modular calcium binding 2) - Rat Genome Database

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Pathways
Gene: Smoc2 (SPARC related modular calcium binding 2) Rattus norvegicus
Analyze
Symbol: Smoc2
Name: SPARC related modular calcium binding 2
RGD ID: 1306681
Description: Predicted to enable calcium ion binding activity; extracellular matrix binding activity; and heparin binding activity. Predicted to be involved in several processes, including positive regulation of endothelial cell chemotaxis; positive regulation of signal transduction; and positive regulation of vascular wound healing. Predicted to act upstream of or within positive regulation of cell-substrate adhesion. Predicted to be located in interstitial matrix. Predicted to be active in basement membrane and extracellular space. Orthologous to human SMOC2 (SPARC related modular calcium binding 2); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC292401; SPARC-related modular calcium-binding protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,935,627 - 64,064,952 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl163,935,647 - 64,064,955 (+)EnsemblGRCr8
mRatBN7.2155,262,472 - 55,391,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx160,133,640 - 60,262,572 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,790,717 - 68,919,413 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,043,596 - 62,172,525 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,242,289 - 56,374,106 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,242,346 - 56,374,120 (+)Ensemblrn6Rnor6.0
Rnor_5.0157,434,118 - 57,565,436 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4153,165,792 - 53,295,145 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera151,480,576 - 51,609,313 (+)NCBICelera
RGSC_v3.1153,168,675 - 53,298,175 (+)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3',5'-cyclic AMP  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
flurbiprofen  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP,ISO)
glafenine  (EXP)
glycidol  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
maneb  (ISO)
menadione  (ISO)
mercaptopurine  (EXP)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
microcystin-LR  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
oxaliplatin  (EXP)
panobinostat  (ISO)
paraquat  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
purine-6-thiol  (EXP)
pyridaben  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (EXP)
sotorasib  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12741954   PMID:16774925   PMID:18757743   PMID:36513634  


Genomics

Comparative Map Data
Smoc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,935,627 - 64,064,952 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl163,935,647 - 64,064,955 (+)EnsemblGRCr8
mRatBN7.2155,262,472 - 55,391,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx160,133,640 - 60,262,572 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,790,717 - 68,919,413 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,043,596 - 62,172,525 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,242,289 - 56,374,106 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,242,346 - 56,374,120 (+)Ensemblrn6Rnor6.0
Rnor_5.0157,434,118 - 57,565,436 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4153,165,792 - 53,295,145 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera151,480,576 - 51,609,313 (+)NCBICelera
RGSC_v3.1153,168,675 - 53,298,175 (+)NCBI
Cytogenetic Map1q12NCBI
SMOC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386168,441,184 - 168,667,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6168,440,656 - 168,673,445 (+)Ensemblhg38GRCh38
GRCh376168,841,864 - 169,068,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366168,584,880 - 168,810,596 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346168,660,586 - 168,886,303NCBI
Celera6169,559,437 - 169,782,279 (+)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6166,267,021 - 166,491,991 (+)NCBIHuRef
CHM1_16169,103,759 - 169,328,184 (+)NCBICHM1_1
T2T-CHM13v2.06169,784,308 - 170,014,051 (+)NCBIT2T-CHM13v2.0
Smoc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391714,499,768 - 14,625,052 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1714,499,768 - 14,625,052 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381714,279,490 - 14,404,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,279,506 - 14,404,790 (+)Ensemblmm10GRCm38
MGSCv371714,416,513 - 14,541,797 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361714,016,132 - 14,141,361 (+)NCBIMGSCv36mm8
Celera1715,080,624 - 15,205,897 (+)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
Smoc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554114,729,706 - 4,822,140 (-)Ensembl
ChiLan1.0NW_0049554114,729,753 - 4,822,140 (-)NCBIChiLan1.0ChiLan1.0
SMOC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25188,680,006 - 188,916,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16186,561,388 - 186,795,664 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06166,430,178 - 166,664,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16171,366,929 - 171,588,320 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6171,366,929 - 171,589,084 (+)EnsemblpanPan2panpan1.1
SMOC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1155,826,354 - 55,986,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl155,825,666 - 55,986,052 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha156,617,795 - 56,777,591 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0156,009,740 - 56,168,234 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl156,009,366 - 56,168,233 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1155,906,584 - 56,065,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0155,753,833 - 55,912,398 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0156,380,993 - 56,539,474 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Smoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946150,202,183 - 150,342,912 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648917,454,270 - 17,594,901 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648917,454,274 - 17,594,894 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMOC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11,193,167 - 1,332,694 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.111,193,163 - 1,332,739 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.212,133,877 - 2,217,364 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMOC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11396,264,170 - 96,477,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1396,264,181 - 96,477,491 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604068,107,603 - 68,398,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smoc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248504,510,598 - 4,661,056 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248504,510,700 - 4,658,579 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Smoc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12183,707,892 - 183,836,974 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Smoc2
1191 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:455
Count of miRNA genes:245
Interacting mature miRNAs:301
Transcripts:ENSRNOT00000019317
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat

Markers in Region
D1Rat207  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8163,973,581 - 63,973,789 (+)Marker Load Pipeline
mRatBN7.2155,300,427 - 55,300,635 (+)MAPPERmRatBN7.2
Rnor_6.0156,282,757 - 56,282,964NCBIRnor6.0
Rnor_5.0157,473,569 - 57,473,776UniSTSRnor5.0
RGSC_v3.4153,203,564 - 53,203,820RGDRGSC3.4
RGSC_v3.4153,203,603 - 53,203,810UniSTSRGSC3.4
Celera151,518,460 - 51,518,667UniSTS
RGSC_v3.1153,206,548 - 53,206,755RGD
RH 3.4 Map1672.2UniSTS
RH 3.4 Map1672.2RGD
RH 2.0 Map1391.3RGD
FHH x ACI Map130.3199RGD
Cytogenetic Map1q12UniSTS
D17Jcs34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2155,313,802 - 55,314,071 (+)MAPPERmRatBN7.2
Rnor_6.0156,296,133 - 56,296,401NCBIRnor6.0
Rnor_5.0157,486,945 - 57,487,213UniSTSRnor5.0
RGSC_v3.4153,216,979 - 53,217,247UniSTSRGSC3.4
Celera151,531,828 - 51,532,096UniSTS
Cytogenetic Map1q12UniSTS
RH130327  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2155,391,499 - 55,391,693 (+)MAPPERmRatBN7.2
Rnor_6.0156,373,791 - 56,373,984NCBIRnor6.0
Rnor_5.0157,565,121 - 57,565,314UniSTSRnor5.0
RGSC_v3.4153,294,929 - 53,295,122UniSTSRGSC3.4
Celera151,609,097 - 51,609,290UniSTS
RH 3.4 Map1673.0UniSTS
Cytogenetic Map1q12UniSTS
BM387775  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2155,380,237 - 55,380,411 (+)MAPPERmRatBN7.2
Rnor_6.0156,362,532 - 56,362,705NCBIRnor6.0
Rnor_5.0157,553,862 - 57,554,035UniSTSRnor5.0
RGSC_v3.4153,283,670 - 53,283,843UniSTSRGSC3.4
Celera151,597,838 - 51,598,011UniSTS
RH 3.4 Map1675.2UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 140 91 90 59 55 59 6 314 155 11 119 76 92 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000019317   ⟹   ENSRNOP00000019317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,935,647 - 64,064,955 (+)Ensembl
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)Ensembl
Rnor_6.0 Ensembl156,242,346 - 56,373,984 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079718   ⟹   ENSRNOP00000071488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,306,478 - 55,391,693 (+)Ensembl
Rnor_6.0 Ensembl156,288,832 - 56,374,120 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109266   ⟹   ENSRNOP00000089764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl163,935,647 - 63,980,380 (+)Ensembl
mRatBN7.2 Ensembl155,262,530 - 55,307,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113274   ⟹   ENSRNOP00000078071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl155,306,478 - 55,386,655 (+)Ensembl
RefSeq Acc Id: NM_001106215   ⟹   NP_001099685
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,935,689 - 64,064,866 (+)NCBI
mRatBN7.2155,262,530 - 55,391,716 (+)NCBI
Rnor_6.0156,242,346 - 56,374,007 (+)NCBI
Rnor_5.0157,434,118 - 57,565,436 (+)NCBI
RGSC_v3.4153,165,792 - 53,295,145 (+)RGD
Celera151,480,576 - 51,609,313 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227958   ⟹   XP_006228020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8163,935,627 - 64,064,952 (+)NCBI
mRatBN7.2155,262,472 - 55,391,804 (+)NCBI
Rnor_6.0156,242,289 - 56,374,106 (+)NCBI
Rnor_5.0157,434,118 - 57,565,436 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001099685 (Get FASTA)   NCBI Sequence Viewer  
  XP_006228020 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68953 (Get FASTA)   NCBI Sequence Viewer  
  EDL99844 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019317
  ENSRNOP00000019317.6
  ENSRNOP00000089764.1
RefSeq Acc Id: NP_001099685   ⟸   NM_001106215
- Peptide Label: precursor
- UniProtKB: B5DF75 (UniProtKB/TrEMBL),   A0A0G2K0K9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228020   ⟸   XM_006227958
- Peptide Label: isoform X1
- UniProtKB: F7FPL2 (UniProtKB/TrEMBL),   A0A0G2K0K9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071488   ⟸   ENSRNOT00000079718
Ensembl Acc Id: ENSRNOP00000019317   ⟸   ENSRNOT00000019317
Ensembl Acc Id: ENSRNOP00000089764   ⟸   ENSRNOT00000109266
Ensembl Acc Id: ENSRNOP00000078071   ⟸   ENSRNOT00000113274
Protein Domains
EF-hand   Kazal-like   Thyroglobulin type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0K9-F1-model_v2 AlphaFold A0A0G2K0K9 1-457 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689636
Promoter ID:EPDNEW_R161
Type:multiple initiation site
Name:Smoc2_1
Description:SPARC related modular calcium binding 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0156,242,332 - 56,242,392EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306681 AgrOrtholog
BioCyc Gene G2FUF-61337 BioCyc
Ensembl Genes ENSRNOG00000014166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019317 ENTREZGENE
  ENSRNOT00000019317.9 UniProtKB/TrEMBL
  ENSRNOT00000109266.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Dev_reg/Prot_inhib UniProtKB/TrEMBL
  EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  Prot_inh_Kazal UniProtKB/TrEMBL
  SMOC2_EC UniProtKB/TrEMBL
  SPARC/Testican_Ca-bd-dom UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
KEGG Report rno:292401 UniProtKB/TrEMBL
NCBI Gene 292401 ENTREZGENE
PANTHER SECRETED MODULAR CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
  SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/TrEMBL
  SPARC_Ca_bdg UniProtKB/TrEMBL
  Thyroglob_assoc UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PhenoGen Smoc2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014166 RatGTEx
SMART KAZAL UniProtKB/TrEMBL
  SM00211 UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
UniProt A0A0G2K0K9 ENTREZGENE
  A0A8I6A7Z3_RAT UniProtKB/TrEMBL
  B5DF75 ENTREZGENE, UniProtKB/TrEMBL
  F7FPL2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Smoc2  SPARC related modular calcium binding 2   Smoc2_predicted  SPARC related modular calcium binding 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Smoc2_predicted  SPARC related modular calcium binding 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED