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Gene: Znrf2 (zinc and ring finger 2) Rattus norvegicus

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Symbol:

Znrf2

Name:

zinc and ring finger 2

RGD ID:

1306645

Description:

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of autophagosome-lysosome fusion; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Predicted to act upstream of or within intracellular potassium ion homeostasis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and membrane. Orthologous to human ZNRF2 (zinc and ring finger 2); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E3 ubiquitin-protein ligase ZNRF2; LOC362367; zinc and ring finger 1; zinc and ring finger 2, E3 ubiquitin protein ligase; Znrf1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNRF2 (zinc and ring finger 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB
Mus musculus (house mouse):	Znrf2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znrf2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNRF2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNRF2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znrf2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNRF2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNRF2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znrf2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Znrf2 (zinc and ring finger 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZNRF2 (zinc and ring finger 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ZNRF2 (zinc and ring finger 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Znrf2 (zinc and ring finger 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	znrf2b (zinc and ring finger 2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	znrf2a (zinc and ring finger 2a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG14435	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG14435	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y71F9AL.10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	znrf2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	85,274,626 - 85,358,083 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	85,280,702 - 85,358,083 (+)	Ensembl				GRCr8
mRatBN7.2	4	83,950,406 - 84,032,676 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	83,949,309 - 84,027,818 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	89,171,393 - 89,248,667 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	84,946,808 - 85,024,087 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	83,361,475 - 83,438,741 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	85,009,350 - 85,090,914 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	85,009,350 - 85,090,914 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	149,717,446 - 149,748,158 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	4	149,666,569 - 149,684,037 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	83,224,883 - 83,361,095 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	78,818,136 - 78,895,341 (+)	NCBI		Celera
RGSC_v3.1	4	83,509,523 - 83,644,305 (+)	NCBI
Cytogenetic Map	4	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bortezomib (ISO)

butanal (ISO)

caffeine (ISO)

CGP 52608 (ISO)

cobalt dichloride (EXP)

Dibutyl phosphate (ISO)

dioxygen (EXP)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

ozone (ISO)

paracetamol (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

rimonabant (ISO)

rotenone (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

succimer (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (ISO)

troglitazone (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of autophagosome-lysosome fusion (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA)

protein K48-linked ubiquitination (IBA)

Cellular Component

cytoplasm (IBA,ISO)

cytoplasmic vesicle membrane (ISO)

endosome (IEA)

lysosome (IEA)

membrane (IBA)

plasma membrane (ISO)

presynaptic membrane (IEA)

protein-containing complex (ISO)

Molecular Function

metal ion binding (IEA)

transferase activity (IEA)

ubiquitin protein ligase activity (IBA,ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19028597	PMID:22797923	PMID:33992580

Genomics

Comparative Map Data

Znrf2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	85,274,626 - 85,358,083 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	85,280,702 - 85,358,083 (+)	Ensembl				GRCr8
mRatBN7.2	4	83,950,406 - 84,032,676 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	83,949,309 - 84,027,818 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	89,171,393 - 89,248,667 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	84,946,808 - 85,024,087 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	83,361,475 - 83,438,741 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	85,009,350 - 85,090,914 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	85,009,350 - 85,090,914 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	149,717,446 - 149,748,158 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	4	149,666,569 - 149,684,037 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	83,224,883 - 83,361,095 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	78,818,136 - 78,895,341 (+)	NCBI		Celera
RGSC_v3.1	4	83,509,523 - 83,644,305 (+)	NCBI
Cytogenetic Map	4	q24	NCBI

ZNRF2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	30,284,597 - 30,367,689 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	30,284,418 - 30,370,457 (+)	Ensembl			hg38	GRCh38
GRCh37	7	30,324,213 - 30,407,305 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	30,290,448 - 30,373,833 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	30,097,162 - 30,180,547	NCBI
Celera	7	30,313,247 - 30,396,631 (+)	NCBI		Celera
Cytogenetic Map	7	p14.3	NCBI
HuRef	7	30,206,083 - 30,289,579 (+)	NCBI		HuRef
CHM1_1	7	30,324,010 - 30,407,338 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	30,422,290 - 30,505,386 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	30,373,689 - 30,457,078 (+)	NCBI

Znrf2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	54,793,901 - 54,867,209 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	54,793,901 - 54,870,485 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	54,816,916 - 54,890,224 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	54,816,916 - 54,893,500 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	54,766,910 - 54,840,218 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	54,746,494 - 54,819,314 (+)	NCBI		MGSCv36	mm8
Celera	6	55,350,483 - 55,423,786 (+)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	27.15	NCBI

Znrf2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	31,550,519 - 31,628,084 (+)	Ensembl
ChiLan1.0	NW_004955410	31,550,519 - 31,628,084 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZNRF2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	35,111,931 - 35,194,163 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	83,436,675 - 83,518,890 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	30,922,235 - 31,006,950 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ZNRF2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	43,029,270 - 43,123,292 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	42,462,394 - 42,557,203 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	42,972,032 - 43,067,204 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	42,972,047 - 43,059,124 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	43,088,065 - 43,183,149 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	42,767,167 - 42,862,262 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	43,125,367 - 43,220,433 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znrf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	87,377,709 - 87,469,585 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	6,589,434 - 6,681,315 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	6,589,440 - 6,681,315 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNRF2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	42,549,846 - 42,651,807 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	18	42,550,571 - 42,651,914 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	46,866,273 - 47,037,101 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNRF2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	27,930,382 - 28,097,754 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	28,014,791 - 28,096,703 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666042	76,599,517 - 76,687,514 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znrf2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624739	385,359 - 497,597 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624739	360,118 - 497,626 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Znrf2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	86,173,398 - 86,250,955 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Znrf2
295 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	1683
Count of miRNA genes:	359
Interacting mature miRNAs:	509
Transcripts:	ENSRNOT00000072271
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	39431983	123203361	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	59753119	104753119	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	41400577	86400577	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	44425024	89425024	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
1357342	Bw40	Body weight QTL 40		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	4	74233320	119233320	Rat
631556	Bp135	Blood pressure QTL 135		0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	80212111	119233320	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	58817672	103817672	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
70167	Bw22	Body weight QTL 22	3.1		body mass (VT:0001259)	body weight (CMO:0000012)	4	74233320	119233320	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	71647492	116647492	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82944895	154403548	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	41400603	86400603	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	75939858	140508796	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	65060960	127749483	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	45429897	149763204	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	51085655	113588029	Rat
61364	Iddm2	Insulin dependent diabetes mellitus QTL 2			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	80216705	104243248	Rat
2317588	Eae27	Experimental allergic encephalomyelitis QTL 27			nervous system integrity trait (VT:0010566)	percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)	4	69036742	114036742	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	40490442	117737312	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	57613339	151163960	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	57613242	102613242	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	57613242	102613242	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	57613242	102613242	Rat
2306794	Ean2	Experimental allergic neuritis QTL 2	6.4		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	4	82790777	97183061	Rat
2306547	Iddm38	Insulin dependent diabetes mellitus QTL 38			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	68353567	113353567	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
2306545	Iddm39	Insulin dependent diabetes mellitus QTL 39			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	78687630	123687630	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	74169813	134199155	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	59836842	104836842	Rat
61406	Scwia1	Streptococcal cell wall induced arthritis QTL 1	2.3		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	4	75939858	140508796	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	45429897	149763204	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	61041057	94638356	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	0.0003	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	84349032	129349032	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63245026	129846354	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	64209744	109209744	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	41400577	86400577	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	57664252	127749483	Rat
2306899	Bp338	Blood pressure QTL 338		0.071	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	82336765	127336765	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58079875	92690793	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63224393	108224393	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	63900458	88813920	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	33538597	116185060	Rat

Markers in Region

RH130994

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	84,027,506 - 84,027,721 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	85,090,603 - 85,090,817	NCBI	Rnor6.0
Rnor_5.0	4	149,747,847 - 149,748,061	UniSTS	Rnor5.0
RGSC_v3.4	4	83,360,784 - 83,360,998	UniSTS	RGSC3.4
Celera	4	78,895,030 - 78,895,244	UniSTS
RH 3.4 Map	4	522.6	UniSTS
Cytogenetic Map	4	q24	UniSTS

AA875513

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	84,023,699 - 84,023,909 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	85,086,796 - 85,087,005	NCBI	Rnor6.0
Rnor_5.0	4	149,744,040 - 149,744,249	UniSTS	Rnor5.0
RGSC_v3.4	4	83,356,977 - 83,357,186	UniSTS	RGSC3.4
Celera	4	78,891,223 - 78,891,432	UniSTS
RH 3.4 Map	4	525.2	UniSTS
Cytogenetic Map	4	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010065675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072271 ⟹ ENSRNOP00000066872

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	85,280,702 - 85,358,083 (+)	Ensembl
mRatBN7.2 Ensembl	4	83,949,309 - 84,027,818 (+)	Ensembl
Rnor_6.0 Ensembl	4	85,009,350 - 85,090,914 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000143545 ⟹ ENSRNOP00000104213

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	85,280,702 - 85,358,083 (+)	Ensembl

RefSeq Acc Id:

NM_001108628 ⟹ NP_001102098

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	85,280,702 - 85,358,083 (+)	NCBI
mRatBN7.2	4	83,950,430 - 84,027,810 (+)	NCBI
Rnor_6.0	4	85,009,350 - 85,090,914 (+)	NCBI
Rnor_5.0	4	149,666,569 - 149,684,037 (+)	NCBI
Rnor_5.0	4	149,717,446 - 149,748,158 (+)	NCBI
RGSC_v3.4	4	83,224,883 - 83,361,095 (+)	RGD
Celera	4	78,818,136 - 78,895,341 (+)	RGD

Sequence:

show sequence

GGCCCGGGGCGGCGCGGACATGGGCGCCAAGCAGAGCGGCCCCGCCGCCAACGGCCGCACCCGC
GCCTACTCGGGCTCGGACCTGCCCTCCGGGACCAGCGGCGGCGGCGGGGCGGACGGCGCTCGGG
CGGCTCGGTTCGCGGCCCCTGTCCCCGGCGCGCAGCAGCCCAGCGCCTCGGCCAGCACGGCGGA
GGATGCTGCTGCTGCGGCGGCGGCACGGCACAGCGGCGGCCTCGGCCCCGGCAGCGCCCGTAGC
CGCTCGCTCGGTGGGGCGGTGGGCAGCGCGGCGAGCGGCCGCGCGGCACAGTCGGCCTTCAGCA
TTCCCAGCAGTGGCGGCGGCAGCGGTGGCCCGTACGGCTCACAGGACTCGGTGCACAGCAGCCC
AGAGGACGGTGTCGGCTCTAGGGACCGGGACCGGCCAGCGGGCGGGGGCCCTGGCGGGCCGCGT
CTGGTGATCGGCTCGCTCCCGGCCCACCTCTCCCCGCACTTGTTTGGAGGATTTAAGTGCCCGG
TATGCTCAAAATTTGTACCCTCAGATGAAATGGATTTGCATCTTGTGATGTGTTTAACAAAGCC
AAGAATAACGTATAATGAGGATGTGCTGAGTAAAGATGCGGGGGAATGTGCAATATGCCTTGAA
GAATTGCAGCAGGGAGACACCATAGCACGACTGCCTTGCCTGTGTATATATCATAAAGGCTGCA
TAGATGAATGGTTTGAAGTAAATAGATCTTGTCCAGAGCACCCTTCGGATTAAGCACACCAGAT
TCCTGTGTTATGGGTTTTCTTGTCTTTTCAAGATGCTTAAGAAATCTAGAAGATTTGAAGATCT
GTCTCTGGAAGAAAATGAGAACTGCAGGCTTATTCAGCCAGAATCTGAGTTCTGGGACACTTGG
GTAGTCCAGAGAAGGACAGGAACTACAGAACTCAGCGTACCAAACTTGCATAAAAGGGACACAC
AGGGATTTTGAAAATGCTGCACATCCTGTACTAGTCACTGCATAGATGACACTGATAAACATTT
TGTATTCAGACGCCAAAGTTAACTCATTTCAAAGTTGATTTACTTTTTATTAAGTTCTGTAGAG
CTGCTGTTTTAGTGTATTTGGTTTTGGTTTGTTTGTTTTGTTTTTTTGTTTTTGTTTTTGTTTT
TTTTTTTAGTTTGGGGACTTTTTATTTTCCCGAACATAATGTTTCTGCATTCACCTATTCTTAT
CTTGAAAACCACACAGTTTCTTTCTTACAAACTCTTCAATGTGAAACCAAGAAATGTAATCAAA
GCAGTATAATATTCTGTGAATGGAGAGTATAATTGAAGTTCTTCCACACACATCCCTCCCCCCC
CACCCCTACCCCCTCCCTGTCCCCCATGTGTGGAAAAGTAGGTTTCTGGGTTGGAGAGCTAAAA
TATGTTAGTAGTTTGAATTAAAGGTTTAATATTATAAAAATGCCATCCAAAGAGTAAATCAAGT
TACATAATTACATTTAGTTAATTAAATGTAGAACTGTCTACTGAACTGCAGTTTCTGAAATACA
TTGTTTCTTCTAAAAGGAAACTGCAGTAGCTTGTTAGCAGTGACCATCTTGCAGCTATGCAACT
TTGAGAAGTCCATATTTGATGGTCCCTCCTCTGGGGCCCAGCGACTCTGTCCTACCAGGTGTCC
TTGTTCTTTCCTGTAATTACTTCATTGTGCTTTGCATCTCCGGGCAGGCTCCCTATGTTTGGGT
AAAATGTTTAGCAAGTTGTAAACGTCATACCTTATGAAAAGGGTGAAATAAACACTTCTGCAGT
GGGACTTGGAGTAATTTGAGGGACATTTTATATACTTTTAAAAATCAGAATTTAATTGGGATGC
CAGATTTCTAGCAACTTGCATCTTTAGTTTTCCAGATAATCTGGAAGTTAGCATTTGATAAATG
ATTTTTTAAGCAAATATAAAGATTTTGTTAATTTATAATTTATTAATGTGTTGTTACTGTAATT
GAACATGTTATGGATACTTTTAAATTCAGTCTTTGTAGAAAGAACTGTATTAAGCAAAATTATG
TGAATAAATATTCCCCCAAAATACATCTGATGGTTAAGAATACTGGAAGAGAGCTATCAGGGCT
GCAACAGTGACTGTCTTTTTAAATAATTATCAAAATATCAAGCAGTAGATCCATGTTTAGTCTC
CAGGGAGAGCATTGCTTCCCTGATCTAGTCAAGGCTGAGCAGGCCTGCTCTCCTGCTGAGCTGC
CCTGGCTGTGGAAGGGTGAGAGTCTCCAGTGCTGCTTTTGTACTCGGACTTGTCCCTGTTGCTT
CTGCCGCTTCCTATGCCCGAGGGCATGCATGTGCAGGAGCAGCTGCTGCCGTGGTGGGCTTGGG
GTAGGGTTGGCCTGATAGTGGAAGCTCTTGCTGCTTTCCTCTGGCTGTAGTCTAGATAGCCCTC
TGCAGTCCACTGTTCGGGTCAGTGGTCTGATCCTGTGGGACAGCTGCCAGCACAGCGCTGTAGG
TGTTCTTTAGGAAGGTTACTCTTCCTTCAAGGGAAATCGTCTTTCCTTAAAGGTTTGTTTTGTT
TTTTGTTTTTCTTTTTTCTGTTAATATGAACTCTGAATCCATTTTACTTCATCTTTGAGTTTGT
GAGCTTTCCTCTCCCCTGGTTTCCCCCAGGGAAGAGCTCTTCAAATGTGAAAAACCACTCTGCC
CTCTACTACCCGTGTGTTGTCTGGAGAAGAGCGACTTCTGCAGTCTGCTCTTCCTTGAGTGCAG
CTGTGCTAATTAATGTTTAGACTCCCTGCAAGATGACCTGCCTCGTGCTAAGCTCACCTTCTTG
GAGTCTCAGCCTCAGTTTACCCTTCCTTCACACTGTCCTCCAGCGGTCTTCGTGGCTTCCATGC
TTTGGCTGCCTCCTCGCTCCTGTGTGTGAGAGAGCTCAGTGCTGTCCTGGCAAGGACATGGACA
CTGGCTGTGCTGAGGTCTGTGCAGTGGTTGCTGAAATCCACTCAGACAGCCTACTTTGGTTTTG
GTTTTGTTTGGTCATATTTTATAAAATTGGCATTTTTACTTTAAATTTTGTCTGCAGTGATTTC
CTAAAAAGAATAATTTAGAAATAGAAGAGAAAAAGAGAAGCTAAGATGTTTCAGTTTCTGTTCA
CAGTTACTATTCTGGGAATGTTCTCTAAGTGATAATTTATGTAATATTGCTTATACTATTTATC
AGTCTGTATGCAGACACTGAGTAGCATCCATCATAAAGTTACAGACTATTCAGCTGAAACTACT
GAATATAGAGACAAAGTAAAAATTGAAAGCCTCAGTTATGAGTTACCCGGCGGGTCAGAGCCTT
CTATAATCTTTGTAAATACCCTCCAGTCAGGTCCACTCTGTCCATAGTGAGTTTACTGCCAATG
TGAATCCTATTTTGATCGTTGTTTTATTCCCGCTTTGCCAGGATATTTAAGACAAAGCACTGTT
TTCTTTGTAAAATGATTTTCTTTCTTTGGCTCCTCTCTAGAGAAATATTTCAACCATAGTTACA
AATCAGACTGTAAGATTGTTTTAAGAAGAAATGTTTATGATTAAGATATGAGCAGTGGTCTCTA
CTTGGCTTGTGTACATGACAGTAGAAGTGACACTGCAAAAGTCCTGGTGACAGTTGGAGTTTAT
AGGTTTGGGCTTTCCAGTGCAAGTCTCTGCACTCGTAAATTTTACATGGTTGTTCTAGTTTTCA
CTTAGATACTGGACTGCAGTCCAGAATAACCAAGGACCATCTTTAGCGTATTTTCAGTGTTCAC
AGCAAAGATATTTCCACCTGACTGAGTTGCCAGAAATGGCAAAATCTTTTCCAGAGTGTATTTC
ATACTGTGTTTCTAAGTATGGGTATGGTGAGGTTTCAGAACACTCATTTCCTACTGGACATGGT
GACTCATGCCAACACTCAGGAACCTGAGGCAGGGGGATTGCCACAAGGTCCAGGCTGGCCTGGG
CAACATAGTGAGTTCTAGGCTAGACTGTCTCAAAAAAAAAAAAAAAAAAAGAAAAAAAGTAATC
ATTTTACTATGTTACAGCAAGACATATTCCTTTTGTTGAGAAAGGGTGTGGGTTCAGTGTAAAT
AGTGCCTGCTTTTTCTGTAGTGACTTAGGGGAAGTAGGGGTTCTCCAGCAGGAGACTCAGGTGA
GCCGTGTGAAACTCTACAATTCAGGAATGGGTGGGTCTGCCATCTGACCGGCAGCTGCACTGTA
CTGACCGCATGATCCAGATAGCTTTCTCATCCCAGAGAAGGTTCCACCTAAGCCAGGCCAAAGC
GTTTGGTTTACAGCATACAGAGTGGCCCTGAGGCAAAGGCACCATGTGCTGCTTGCACGTCTCT
AGTGTGCTTAGCAATTTTTCTGTGGGTTTGGTCTACCCTGGGGTAAACTCCACACTCACTGACA
GTGAGAGATGAGACACGGAGGGTCCCTTGTTATTCAGCATACAGAGATTTTAACTTGACTTTAA
AATTGTAATATGTCAGTCCTTTGGAGCCCATTCTCCTATCGTTCCTAGAGTGTATAACTTCTGA
TATTTTCTTAGCTATGTGATATAACTAGTTACCTTACCTCTTTTACCCTACTCTTTCTCCATCC
CACAACTTGTACTGAGTATGAATGGCTGTTGCTTGGAGTACTCCTGAAATCATTGATAAAATTG
TTGGTGATAATGTACCCAACCAGTACTTTATACTATATTCTGTAAATGCACTTAAGCTAGGAAA
TAGACTTTAAAAAAAAAAAATCAGAGTTCTGTTTTAAATAGGAATACCTGATTTCCTAAGTCTG
TTGACTTTCTGTGAGATACAAGACCTTGGACACCAGACATGTTAATGCTTACTTTCAGTTTAAC
ATACACCATCACTGTCCTCACAAGGTTGTTTTCAGATATTCAAACTATTCTTAATTTCTGAGCA
GTGCGTGCGTGCGTGCGTGCGTGCGTGCATGTGTGTGTGTGTGTAGAGAAGCAGAGAGCAGTGT
GGCATGAACTAACATCTCTACATACAAAAATGACAAATGTGATACTGAAGCACTTACTAATGTG
CATTTCTTAGCTCTGTCCCTGGACCCTGAGAATCTCAAGATTGGATATCGGAAGTAACAGTTCT
CTTACCAATCACTGTCTGCCCATGCCTGCCTTTTCTGATTTAGTATGTTGGAGTTGGCATGTGC
CTATCATCTATGTGGGAAACTTAACTGCTTGCATATTGTTAGCAGTAACTGTGGTGACAGAACT
GTTTCCTTTTATTAGTCAAGCTCGTCTGATAGCCTGCACCTGAGATGTTGAGGCAGAAGCAGAG
GATCATGGGTTTGAAACCAGTTTGAGCTGCACAGTGAGTTTGAGACAAGCCTGAACTACAACGT
GAGAGCTTGTCTCGTGGTTGTAGTCACGTTAGAGTGTTGGATGTGTGCTGTCTGGTTAGGAGAC
TCTGGTCTAAGAAACAACAGGAACCTTGGACTCGATGGCACTAAGTAACAAGTCATTGTGTTGC
TTTGTAGGTGACTTGTTATATCAGTTTCTTTGCTTGAAAAATCACAATATTTACCTCTGATTTA
TTCATGTTTTCTACAACTCTTCTATAATACCTCTTAATTTCCTCTATTAGAAAGTATTTTGTTC
TTGTTAAACAAGGCCCTAAAAGCATTGATCATAAGAAATGAGAAAATGTATTAGGAACAGCTTG
TATTAGTGTGTTCTGAACAGAAACGGAACAATTCATCATTGATATTTTAATAAATAAAATTTCC
AAATGATCTCATTA

hide sequence

RefSeq Acc Id:

XM_039107798 ⟹ XP_038963726

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	85,274,626 - 85,351,279 (+)	NCBI
mRatBN7.2	4	83,950,415 - 84,022,807 (+)	NCBI

RefSeq Acc Id:

XR_010065675

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	85,274,626 - 85,349,472 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102098	(Get FASTA)	NCBI Sequence Viewer
	XP_038963726	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL88107	(Get FASTA)	NCBI Sequence Viewer
	EDL88108	(Get FASTA)	NCBI Sequence Viewer
	EDL88109	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000066872
	ENSRNOP00000066872.2
	ENSRNOP00000104213.1

RefSeq Acc Id:

NP_001102098 ⟸ NM_001108628

- UniProtKB:

M0RBD9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGAKQSGPAANGRTRAYSGSDLPSGTSGGGGADGARAARFAAPVPGAQQPSASASTAEDAAAAA
AARHSGGLGPGSARSRSLGGAVGSAASGRAAQSAFSIPSSGGGSGGPYGSQDSVHSSPEDGVGS
RDRDRPAGGGPGGPRLVIGSLPAHLSPHLFGGFKCPVCSKFVPSDEMDLHLVMCLTKPRITYNE
DVLSKDAGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNRSCPEHPSD

hide sequence

Ensembl Acc Id:

ENSRNOP00000066872 ⟸ ENSRNOT00000072271

RefSeq Acc Id:	XP_038963726 ⟸ XM_039107798
- Peptide Label:	isoform X1
- UniProtKB:	M0RBD9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000104213 ⟸ ENSRNOT00000143545

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0RBD9-F1-model_v2	AlphaFold	M0RBD9	1-245	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693068

Promoter ID:

EPDNEW_R3593

Type:

initiation region

Name:

Znrf2_1

Description:

zinc and ring finger 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	85,009,291 - 85,009,351	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306645	AgrOrtholog
BioCyc Gene	G2FUF-44751	BioCyc
Ensembl Genes	ENSRNOG00000049057	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000072271	ENTREZGENE
	ENSRNOT00000072271.3	UniProtKB/TrEMBL
	ENSRNOT00000143545.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	ZNRF_ubiq-protein_ligase	UniProtKB/TrEMBL
KEGG Report	rno:362367	UniProtKB/TrEMBL
NCBI Gene	362367	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE ZNRF2	UniProtKB/TrEMBL
Pfam	zf-RING_2	UniProtKB/TrEMBL
PhenoGen	Znrf2	PhenoGen
PROSITE	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000049057	RatGTEx
SMART	RING	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A0ABK0LSC4_RAT	UniProtKB/TrEMBL
	A6K0V9_RAT	UniProtKB/TrEMBL
	M0RBD9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-18	Znrf2	zinc and ring finger 2	Znrf2	zinc and ring finger 2, E3 ubiquitin protein ligase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-01	Znrf2	zinc and ring finger 2, E3 ubiquitin protein ligase	Znrf2	zinc and ring finger 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	Znrf2	zinc and ring finger 2	Znrf1	zinc and ring finger 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Znrf1	zinc and ring finger 1	Znrf1_predicted	zinc and ring finger 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Znrf1_predicted	zinc and ring finger 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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