Comtd1 (catechol-O-methyltransferase domain containing 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Comtd1 (catechol-O-methyltransferase domain containing 1) Rattus norvegicus
Analyze
Symbol: Comtd1
Name: catechol-O-methyltransferase domain containing 1
RGD ID: 1306581
Description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Orthologous to human COMTD1 (catechol-O-methyltransferase domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: catechol O-methyltransferase domain-containing protein 1; LOC305685
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8152,509,121 - 2,512,232 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl152,509,032 - 2,512,232 (+)EnsemblGRCr8
mRatBN7.2152,459,783 - 2,462,895 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,459,783 - 2,462,895 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx152,467,227 - 2,470,346 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,853,673 - 3,856,792 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0152,466,022 - 2,469,141 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0152,631,529 - 2,634,640 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl152,631,529 - 2,634,640 (+)Ensemblrn6Rnor6.0
Rnor_5.0152,612,542 - 2,615,653 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4152,512,204 - 2,515,315 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera152,119,181 - 2,122,292 (-)NCBICelera
RGSC_v3.1152,512,247 - 2,514,099 (+)NCBI
Cytogenetic Map15p16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
eugenol  (EXP)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
L-methionine  (ISO)
methimazole  (EXP)
methylphenidate  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
methylation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18614015   PMID:34800366  


Genomics

Comparative Map Data
Comtd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8152,509,121 - 2,512,232 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl152,509,032 - 2,512,232 (+)EnsemblGRCr8
mRatBN7.2152,459,783 - 2,462,895 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,459,783 - 2,462,895 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx152,467,227 - 2,470,346 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,853,673 - 3,856,792 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0152,466,022 - 2,469,141 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0152,631,529 - 2,634,640 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl152,631,529 - 2,634,640 (+)Ensemblrn6Rnor6.0
Rnor_5.0152,612,542 - 2,615,653 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4152,512,204 - 2,515,315 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera152,119,181 - 2,122,292 (-)NCBICelera
RGSC_v3.1152,512,247 - 2,514,099 (+)NCBI
Cytogenetic Map15p16NCBI
COMTD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381075,233,641 - 75,235,957 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1075,233,641 - 75,236,075 (-)Ensemblhg38GRCh38
GRCh371076,993,399 - 76,995,715 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361076,663,735 - 76,665,776 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341076,663,735 - 76,665,776NCBI
Celera1070,281,988 - 70,284,029 (-)NCBICelera
Cytogenetic Map10q22.2NCBI
HuRef1070,992,121 - 70,994,162 (-)NCBIHuRef
CHM1_11077,275,551 - 77,277,592 (-)NCBICHM1_1
T2T-CHM13v2.01076,107,149 - 76,109,465 (-)NCBIT2T-CHM13v2.0
Comtd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391421,895,929 - 21,898,978 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1421,895,923 - 21,899,045 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381421,845,861 - 21,848,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1421,845,855 - 21,848,977 (-)Ensemblmm10GRCm38
MGSCv371422,665,083 - 22,668,132 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361420,634,413 - 20,637,462 (-)NCBIMGSCv36mm8
Celera1418,228,558 - 18,231,648 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.92NCBI
Comtd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543716,853,518 - 16,854,867 (+)Ensembl
ChiLan1.0NW_00495543716,853,516 - 16,854,867 (+)NCBIChiLan1.0ChiLan1.0
COMTD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2887,394,214 - 87,396,365 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11087,399,539 - 87,401,670 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01071,766,326 - 71,768,451 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11074,429,376 - 74,431,497 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1074,429,376 - 74,431,497 (-)EnsemblpanPan2panpan1.1
COMTD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1425,464,448 - 25,466,218 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl425,464,454 - 25,466,323 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha425,597,675 - 25,601,325 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0425,745,174 - 25,748,819 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl425,747,121 - 25,748,809 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1425,640,221 - 25,643,858 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0425,840,812 - 25,844,442 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0426,199,026 - 26,200,730 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Comtd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721355,624,859 - 55,629,829 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365214,116,995 - 4,120,184 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365214,116,893 - 4,121,782 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COMTD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1477,782,672 - 77,786,837 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11477,783,064 - 77,786,871 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
COMTD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1956,135,882 - 56,142,754 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl956,136,659 - 56,138,553 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604816,623,941 - 16,628,822 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Comtd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247548,603,257 - 8,610,243 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247548,604,935 - 8,606,633 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Comtd1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11291,621,705 - 91,624,802 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Comtd1
14 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:306
Count of miRNA genes:191
Interacting mature miRNAs:227
Transcripts:ENSRNOT00000018897
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15115177511Rat

Markers in Region
RH142258  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,461,323 - 2,461,493 (+)MAPPERmRatBN7.2
Rnor_6.0152,633,070 - 2,633,239NCBIRnor6.0
Rnor_5.0152,614,083 - 2,614,252UniSTSRnor5.0
RGSC_v3.4152,513,745 - 2,513,914UniSTSRGSC3.4
Celera152,120,582 - 2,120,751UniSTS
RH 3.4 Map1545.3UniSTS
Cytogenetic Map15p16UniSTS
RH135028  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,462,675 - 2,462,856 (+)MAPPERmRatBN7.2
Rnor_6.0152,634,421 - 2,634,601NCBIRnor6.0
Rnor_5.0152,615,434 - 2,615,614UniSTSRnor5.0
RGSC_v3.4152,515,096 - 2,515,276UniSTSRGSC3.4
Celera152,119,220 - 2,119,400UniSTS
RH 3.4 Map1544.6UniSTS
Cytogenetic Map15p16UniSTS
RH141113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,461,338 - 2,461,538 (+)MAPPERmRatBN7.2
Rnor_6.0152,633,085 - 2,633,284NCBIRnor6.0
Rnor_5.0152,614,098 - 2,614,297UniSTSRnor5.0
RGSC_v3.4152,513,760 - 2,513,959UniSTSRGSC3.4
Celera152,120,537 - 2,120,736UniSTS
RH 3.4 Map4632.72UniSTS
Cytogenetic Map15p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018897   ⟹   ENSRNOP00000018897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl152,509,087 - 2,512,232 (+)Ensembl
mRatBN7.2 Ensembl152,459,783 - 2,462,895 (+)Ensembl
Rnor_6.0 Ensembl152,631,529 - 2,634,640 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098144   ⟹   ENSRNOP00000079281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl152,509,032 - 2,512,232 (+)Ensembl
mRatBN7.2 Ensembl152,459,805 - 2,462,895 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111951   ⟹   ENSRNOP00000090138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl152,509,087 - 2,512,232 (+)Ensembl
mRatBN7.2 Ensembl152,459,783 - 2,462,895 (+)Ensembl
RefSeq Acc Id: NM_001107249   ⟹   NP_001100719
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8152,509,121 - 2,512,232 (+)NCBI
mRatBN7.2152,459,783 - 2,462,895 (+)NCBI
Rnor_6.0152,631,529 - 2,634,640 (+)NCBI
Rnor_5.0152,612,542 - 2,615,653 (+)NCBI
RGSC_v3.4152,512,204 - 2,515,315 (+)RGD
Celera152,119,181 - 2,122,292 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100719 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86279 (Get FASTA)   NCBI Sequence Viewer  
  EDL86280 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018897
  ENSRNOP00000018897.4
  ENSRNOP00000079281.2
  ENSRNOP00000090138.1
RefSeq Acc Id: NP_001100719   ⟸   NM_001107249
- UniProtKB: D3ZM21 (UniProtKB/TrEMBL),   A6KKT5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018897   ⟸   ENSRNOT00000018897
Ensembl Acc Id: ENSRNOP00000079281   ⟸   ENSRNOT00000098144
Ensembl Acc Id: ENSRNOP00000090138   ⟸   ENSRNOT00000111951

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZM21-F1-model_v2 AlphaFold D3ZM21 1-262 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699545
Promoter ID:EPDNEW_R10069
Type:initiation region
Name:Comtd1_1
Description:catechol-O-methyltransferase domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0152,631,560 - 2,631,620EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306581 AgrOrtholog
BioCyc Gene G2FUF-14602 BioCyc
BioCyc Pathway PWY-6334 [L-dopa degradation I (mammalian)] BioCyc
  PWY-6342 [noradrenaline and adrenaline degradation] BioCyc
  PWY18C3-23 [guaiacol biosynthesis] BioCyc
  PWY6666-2 [dopamine degradation] BioCyc
BioCyc Pathway Image PWY-6334 BioCyc
  PWY-6342 BioCyc
  PWY18C3-23 BioCyc
  PWY6666-2 BioCyc
Ensembl Genes ENSRNOG00000013968 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018897 ENTREZGENE
  ENSRNOT00000018897.7 UniProtKB/TrEMBL
  ENSRNOT00000098144.2 UniProtKB/TrEMBL
  ENSRNOT00000111951.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Cation-dep_OMT UniProtKB/TrEMBL
  O-MeTrfase_3 UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
KEGG Report rno:305685 UniProtKB/TrEMBL
NCBI Gene 305685 ENTREZGENE
PANTHER CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  O-METHYLTRANSFERASE-RELATED UniProtKB/TrEMBL
Pfam Methyltransf_3 UniProtKB/TrEMBL
PhenoGen Comtd1 PhenoGen
PROSITE SAM_OMT_I UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013968 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8I5ZME1_RAT UniProtKB/TrEMBL
  A0A8I6A9G9_RAT UniProtKB/TrEMBL
  A6KKT5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZM21 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Comtd1  catechol-O-methyltransferase domain containing 1   Comtd1_predicted  catechol-O-methyltransferase domain containing 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Comtd1_predicted  catechol-O-methyltransferase domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED