Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Usp1 | Rat | (-)-demecolcine | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of USP1 mRNA | CTD | PMID:23649840 | Usp1 | Rat | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | o,p'-DDT results in increased expression of USP1 mRNA | CTD | PMID:24096037 | Usp1 | Rat | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | EXP | | 6480464 | o,p'-DDT results in increased expression of USP1 mRNA | CTD | PMID:24096037 | Usp1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of USP1 mRNA | CTD | PMID:22206623 | Usp1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of USP1 mRNA | CTD | PMID:22206623 | Usp1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of USP1 mRNA | CTD | PMID:17942748 | Usp1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of USP1 mRNA | CTD | PMID:17942748|PMID:24096037 | Usp1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of USP1 mRNA | CTD | PMID:24096037 | Usp1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Usp1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of USP1 mRNA | CTD | PMID:17555576 | Usp1 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Usp1 (Mus musculus) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of USP1 mRNA | CTD | PMID:30294300 | Usp1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of USP1 mRNA | CTD | PMID:17942748 | Usp1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of USP1 mRNA | CTD | PMID:34747641 | Usp1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Usp1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of USP1 mRNA | CTD | PMID:21570461 | Usp1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of USP1 mRNA | CTD | PMID:21346803 | Usp1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of USP1 mRNA | CTD | PMID:21346803 | Usp1 | Rat | 2-methylcholine | affects expression | ISO | USP1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of USP1 mRNA | CTD | PMID:21179406 | Usp1 | Rat | 2-palmitoylglycerol | increases expression | ISO | USP1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of USP1 mRNA | CTD | PMID:37199045 | Usp1 | Rat | aflatoxin M1 | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of USP1 mRNA | CTD | PMID:30928695 | Usp1 | Rat | all-trans-retinoic acid | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of USP1 mRNA | CTD | PMID:16249480|PMID:33167477 | Usp1 | Rat | aristolochic acid A | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of USP1 mRNA | CTD | PMID:33212167 | Usp1 | Rat | Aroclor 1254 | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of USP1 mRNA | CTD | PMID:23650126 | Usp1 | Rat | arsenite(3-) | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | arsenite results in decreased expression of USP1 mRNA | CTD | PMID:33053406 | Usp1 | Rat | benzo[a]pyrene | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of USP1 mRNA | CTD | PMID:22228805 | Usp1 | Rat | benzo[a]pyrene | increases expression | ISO | USP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of USP1 mRNA | CTD | PMID:32234424 | Usp1 | Rat | benzo[a]pyrene | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of USP1 mRNA | CTD | PMID:22228805 | Usp1 | Rat | benzo[a]pyrene | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of USP1 mRNA | CTD | PMID:22316170 | Usp1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of USP1 mRNA | CTD | PMID:20382639 | Usp1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of USP1 mRNA | CTD | PMID:25181051|PMID:32145629 | Usp1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of USP1 mRNA | CTD | PMID:34947998 | Usp1 | Rat | bisphenol A | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of USP1 mRNA | CTD | PMID:33221593 | Usp1 | Rat | bisphenol A | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of USP1 mRNA | CTD | PMID:29275510 | Usp1 | Rat | bisphenol F | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of USP1 mRNA | CTD | PMID:38685157 | Usp1 | Rat | cadmium atom | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of USP1 mRNA; more ... | CTD | PMID:28111341|PMID:37236586 | Usp1 | Rat | cadmium dichloride | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of USP1 mRNA; more ... | CTD | PMID:28111341|PMID:37236586 | Usp1 | Rat | cadmium dichloride | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of USP1 mRNA | CTD | PMID:38174414 | Usp1 | Rat | caffeine | decreases phosphorylation | ISO | USP1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of USP1 protein | CTD | PMID:35688186 | Usp1 | Rat | calcitriol | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of USP1 mRNA | CTD | PMID:21592394 | Usp1 | Rat | calcitriol | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of USP1 mRNA | CTD | PMID:21592394 | Usp1 | Rat | carbamazepine | affects expression | ISO | USP1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of USP1 mRNA | CTD | PMID:25979313 | Usp1 | Rat | CGP 52608 | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to USP1 gene] | CTD | PMID:28238834 | Usp1 | Rat | cisplatin | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of USP1 mRNA | CTD | PMID:27392435 | Usp1 | Rat | copper atom | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Copper results in increased expression of USP1 mRNA | CTD | PMID:16629173 | Usp1 | Rat | copper(0) | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Copper results in increased expression of USP1 mRNA | CTD | PMID:16629173 | Usp1 | Rat | copper(II) sulfate | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of USP1 mRNA | CTD | PMID:19549813 | Usp1 | Rat | coumarin | increases phosphorylation | ISO | USP1 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of USP1 protein | CTD | PMID:35688186 | Usp1 | Rat | coumestrol | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of USP1 mRNA; [Coumestrol co-treated with resveratrol] more ... | CTD | PMID:19167446 | Usp1 | Rat | coumestrol | increases expression | ISO | USP1 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of USP1 mRNA | CTD | PMID:19167446 | Usp1 | Rat | cyclosporin A | increases expression | ISO | USP1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of USP1 mRNA | CTD | PMID:20106945|PMID:27989131 | Usp1 | Rat | Dibutyl phosphate | affects expression | ISO | USP1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of USP1 mRNA | CTD | PMID:37042841 | Usp1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of USP1 mRNA | CTD | PMID:21266533 | Usp1 | Rat | dibutyl phthalate | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of USP1 mRNA | CTD | PMID:17361019|PMID:21266533 | Usp1 | Rat | dicrotophos | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of USP1 mRNA | CTD | PMID:28302478 | Usp1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of USP1 mRNA | CTD | PMID:29391264 | Usp1 | Rat | Enterolactone | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of USP1 mRNA | CTD | PMID:19167446 | Usp1 | Rat | fenofibrate | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of USP1 mRNA | CTD | PMID:21318169 | Usp1 | Rat | fenofibrate | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA] | CTD | PMID:21318169 | Usp1 | Rat | folic acid | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of USP1 mRNA | CTD | PMID:22206623 | Usp1 | Rat | FR900359 | decreases phosphorylation | ISO | USP1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of USP1 protein | CTD | PMID:37730182 | Usp1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of USP1 mRNA | CTD | PMID:22061828 | Usp1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of USP1 mRNA | CTD | PMID:33387578 | Usp1 | Rat | gold atom | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Gold results in decreased expression of USP1 mRNA | CTD | PMID:25523186 | Usp1 | Rat | gold(0) | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Gold results in decreased expression of USP1 mRNA | CTD | PMID:25523186 | Usp1 | Rat | hexadecanoic acid | increases phosphorylation | ISO | USP1 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of USP1 protein | CTD | PMID:28073184 | Usp1 | Rat | hydrogen peroxide | affects expression | ISO | USP1 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of USP1 mRNA | CTD | PMID:21179406 | Usp1 | Rat | kojic acid | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | kojic acid results in decreased expression of USP1 mRNA | CTD | PMID:16595896 | Usp1 | Rat | methidathion | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | methidathion results in increased expression of USP1 mRNA | CTD | PMID:34813904 | Usp1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of USP1 mRNA | CTD | PMID:25729387 | Usp1 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of USP1 mRNA | CTD | PMID:25729387 | Usp1 | Rat | paracetamol | affects expression | ISO | Usp1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of USP1 mRNA | CTD | PMID:17562736 | Usp1 | Rat | phenobarbital | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of USP1 mRNA | CTD | PMID:23091169 | Usp1 | Rat | phlorizin | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Phlorhizin results in increased expression of USP1 mRNA | CTD | PMID:22538082 | Usp1 | Rat | pirinixic acid | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in increased expression of USP1 mRNA] | CTD | PMID:21318169 | Usp1 | Rat | pirinixic acid | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of USP1 mRNA | CTD | PMID:18301758|PMID:21318169 | Usp1 | Rat | piroxicam | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of USP1 mRNA | CTD | PMID:21858171 | Usp1 | Rat | quercetin | decreases phosphorylation | ISO | USP1 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of USP1 protein | CTD | PMID:35688186 | Usp1 | Rat | resveratrol | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of USP1 mRNA | CTD | PMID:19167446 | Usp1 | Rat | sodium arsenite | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of USP1 mRNA | CTD | PMID:38568856 | Usp1 | Rat | sodium arsenite | increases expression | ISO | USP1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of USP1 mRNA; sodium arsenite results in increased expression more ... | CTD | PMID:30528433|PMID:39719251 | Usp1 | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of USP1 mRNA | CTD | PMID:22110744 | Usp1 | Rat | succimer | multiple interactions | ISO | Usp1 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of USP1 mRNA; [Succimer co-treated more ... | CTD | PMID:21641980|PMID:26378955 | Usp1 | Rat | succimer | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of USP1 mRNA | CTD | PMID:26378955 | Usp1 | Rat | tamoxifen | affects expression | ISO | Usp1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of USP1 mRNA | CTD | PMID:17555576 | Usp1 | Rat | testosterone | multiple interactions | ISO | USP1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of USP1 mRNA | CTD | PMID:21592394 | Usp1 | Rat | testosterone | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of USP1 mRNA | CTD | PMID:21592394 | Usp1 | Rat | testosterone enanthate | affects expression | ISO | USP1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of USP1 mRNA | CTD | PMID:17440010 | Usp1 | Rat | tetrachloromethane | increases expression | ISO | Usp1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of USP1 mRNA | CTD | PMID:31919559 | Usp1 | Rat | thimerosal | decreases expression | ISO | USP1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of USP1 mRNA | CTD | PMID:27188386 | Usp1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of USP1 mRNA | CTD | PMID:34492290 | Usp1 | Rat | titanium dioxide | decreases methylation | ISO | Usp1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of USP1 promoter | CTD | PMID:35295148 | Usp1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of USP1 mRNA | CTD | PMID:25729387 | Usp1 | Rat | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of USP1 mRNA | CTD | PMID:30589522 | Usp1 | Rat | triphenyl phosphate | affects expression | ISO | USP1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of USP1 mRNA | CTD | PMID:37042841 | Usp1 | Rat | trovafloxacin | decreases expression | ISO | Usp1 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of USP1 mRNA | CTD | PMID:35537566 | Usp1 | Rat | valproic acid | affects expression | ISO | Usp1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of USP1 mRNA | CTD | PMID:17963808 | | |||||||||||||||||||||||||||||||||||||||||||||||||






















