Usp1 (ubiquitin specific peptidase 1) - Rat Genome Database

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Pathways
Gene: Usp1 (ubiquitin specific peptidase 1) Rattus norvegicus
Analyze
Symbol: Usp1
Name: ubiquitin specific peptidase 1
RGD ID: 1306461
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including monoubiquitinated protein deubiquitination; positive regulation of receptor signaling pathway via JAK-STAT; and regulation of protein stability. Predicted to act upstream of or within cell surface receptor signaling pathway via JAK-STAT and skeletal system development. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human USP1 (ubiquitin specific peptidase 1); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: deubiquitinating enzyme 1; LOC313387; MGC108773; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin specific peptdiase 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85118,703,056 - 118,714,426 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5118,702,868 - 118,714,434 (+)EnsemblGRCr8
mRatBN7.25113,587,564 - 113,598,934 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5113,587,564 - 113,598,932 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5116,161,227 - 116,172,610 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05117,886,562 - 117,897,946 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05117,949,094 - 117,960,477 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05117,583,502 - 117,594,872 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5117,583,502 - 117,594,870 (+)Ensemblrn6Rnor6.0
Rnor_5.05121,525,009 - 121,536,379 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45119,364,515 - 119,375,885 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5112,151,349 - 112,162,719 (+)NCBICelera
RGSC_v3.15119,369,740 - 119,381,109 (+)NCBI
Cytogenetic Map5q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
fenofibrate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
kojic acid  (ISO)
methidathion  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
phenobarbital  (ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP,ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16531995   PMID:18082604   PMID:20129063   PMID:21925315   PMID:36859264  


Genomics

Comparative Map Data
Usp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85118,703,056 - 118,714,426 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5118,702,868 - 118,714,434 (+)EnsemblGRCr8
mRatBN7.25113,587,564 - 113,598,934 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5113,587,564 - 113,598,932 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5116,161,227 - 116,172,610 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05117,886,562 - 117,897,946 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05117,949,094 - 117,960,477 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05117,583,502 - 117,594,872 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5117,583,502 - 117,594,870 (+)Ensemblrn6Rnor6.0
Rnor_5.05121,525,009 - 121,536,379 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45119,364,515 - 119,375,885 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5112,151,349 - 112,162,719 (+)NCBICelera
RGSC_v3.15119,369,740 - 119,381,109 (+)NCBI
Cytogenetic Map5q33NCBI
USP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,436,395 - 62,451,804 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,436,041 - 62,451,804 (+)Ensemblhg38GRCh38
GRCh37162,902,066 - 62,917,475 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,674,563 - 62,690,063 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34162,614,699 - 62,629,430NCBI
Celera161,191,184 - 61,206,684 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef161,014,014 - 61,029,515 (+)NCBIHuRef
CHM1_1163,017,306 - 63,032,808 (+)NCBICHM1_1
T2T-CHM13v2.0162,314,982 - 62,330,391 (+)NCBIT2T-CHM13v2.0
Usp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39498,812,047 - 98,823,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl498,812,047 - 98,823,780 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38498,923,810 - 98,935,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl498,923,810 - 98,935,543 (+)Ensemblmm10GRCm38
MGSCv37498,590,501 - 98,602,224 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36498,415,828 - 98,427,551 (+)NCBIMGSCv36mm8
Celera497,290,878 - 97,302,597 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.6NCBI
Usp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542327,237,003 - 27,251,892 (-)Ensembl
ChiLan1.0NW_00495542327,236,242 - 27,254,064 (-)NCBIChiLan1.0ChiLan1.0
USP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21164,400,198 - 164,427,944 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,549,851 - 163,577,601 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,694,775 - 61,710,216 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,509,781 - 63,525,446 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,510,196 - 63,525,446 (+)EnsemblpanPan2panpan1.1
USP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1547,655,533 - 47,666,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl547,656,039 - 47,666,210 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha547,709,417 - 47,728,116 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0547,832,714 - 47,851,368 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl547,839,987 - 47,850,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1547,787,677 - 47,806,321 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0547,734,051 - 47,752,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0547,996,113 - 48,014,814 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Usp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505875,834,633 - 75,844,494 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936692148,116 - 159,170 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936692147,699 - 159,921 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6149,970,915 - 149,985,509 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16149,971,471 - 149,985,946 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
USP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12070,602,300 - 70,617,280 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2070,603,056 - 70,614,069 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603346,836,799 - 46,851,713 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474231,391,022 - 31,399,724 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474231,390,279 - 31,399,789 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Usp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1155,579,022 - 55,596,221 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Usp1
50 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:63
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000010933
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1298077Bp157Blood pressure QTL 157arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5114474223121056531Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
BF386522  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25113,597,258 - 113,597,409 (+)MAPPERmRatBN7.2
Rnor_6.05117,593,197 - 117,593,347NCBIRnor6.0
Rnor_5.05121,534,704 - 121,534,854UniSTSRnor5.0
RGSC_v3.45119,374,210 - 119,374,360UniSTSRGSC3.4
Celera5112,161,044 - 112,161,194UniSTS
RH 3.4 Map5792.0UniSTS
Cytogenetic Map5q33UniSTS
RH129697  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25113,598,647 - 113,598,830 (+)MAPPERmRatBN7.2
Rnor_6.05117,594,586 - 117,594,768NCBIRnor6.0
Rnor_5.05121,536,093 - 121,536,275UniSTSRnor5.0
RGSC_v3.45119,375,599 - 119,375,781UniSTSRGSC3.4
Celera5112,162,433 - 112,162,615UniSTS
RH 3.4 Map5791.3UniSTS
Cytogenetic Map5q33UniSTS
RH142394  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25113,598,233 - 113,598,414 (+)MAPPERmRatBN7.2
Rnor_6.05117,594,172 - 117,594,352NCBIRnor6.0
Rnor_5.05121,535,679 - 121,535,859UniSTSRnor5.0
RGSC_v3.45119,375,185 - 119,375,365UniSTSRGSC3.4
Celera5112,162,019 - 112,162,199UniSTS
Cytogenetic Map5q33UniSTS
BE106944  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25113,596,852 - 113,597,009 (+)MAPPERmRatBN7.2
Rnor_6.05117,592,791 - 117,592,947NCBIRnor6.0
Rnor_5.05121,534,298 - 121,534,454UniSTSRnor5.0
RGSC_v3.45119,373,804 - 119,373,960UniSTSRGSC3.4
Celera5112,160,638 - 112,160,794UniSTS
RH 3.4 Map5798.9UniSTS
Cytogenetic Map5q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010933   ⟹   ENSRNOP00000010935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,702,868 - 118,714,434 (+)Ensembl
mRatBN7.2 Ensembl5113,587,564 - 113,598,932 (+)Ensembl
Rnor_6.0 Ensembl5117,583,502 - 117,594,870 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084640   ⟹   ENSRNOP00000069155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5117,586,103 - 117,594,335 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149142   ⟹   ENSRNOP00000101612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5118,702,868 - 118,714,434 (+)Ensembl
RefSeq Acc Id: NM_001015015   ⟹   NP_001015015
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85118,703,056 - 118,714,426 (+)NCBI
mRatBN7.25113,587,564 - 113,598,934 (+)NCBI
Rnor_6.05117,583,502 - 117,594,872 (+)NCBI
Rnor_5.05121,525,009 - 121,536,379 (+)NCBI
RGSC_v3.45119,364,515 - 119,375,885 (+)RGD
Celera5112,151,349 - 112,162,719 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001015015 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH92574 (Get FASTA)   NCBI Sequence Viewer  
  EDL97803 (Get FASTA)   NCBI Sequence Viewer  
  EDL97804 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010935
  ENSRNOP00000010935.4
GenBank Protein Q569C3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001015015   ⟸   NM_001015015
- UniProtKB: Q569C3 (UniProtKB/Swiss-Prot),   A6JRL2 (UniProtKB/TrEMBL),   A6JRL1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069155   ⟸   ENSRNOT00000084640
Ensembl Acc Id: ENSRNOP00000010935   ⟸   ENSRNOT00000010933
Ensembl Acc Id: ENSRNOP00000101612   ⟸   ENSRNOT00000149142
Protein Domains
USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q569C3-F1-model_v2 AlphaFold Q569C3 1-784 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693852
Promoter ID:EPDNEW_R4377
Type:initiation region
Name:Usp1_1
Description:ubiquitin specific peptidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05117,583,593 - 117,583,653EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306461 AgrOrtholog
BioCyc Gene G2FUF-40582 BioCyc
Ensembl Genes ENSRNOG00000007890 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010933 ENTREZGENE
  ENSRNOT00000010933.7 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7113947 IMAGE-MGC_LOAD
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Peptidase_C19 UniProtKB/Swiss-Prot
  Peptidase_C19_UCH UniProtKB/Swiss-Prot
  USP1 UniProtKB/Swiss-Prot
  USP_CS UniProtKB/Swiss-Prot
  USP_dom UniProtKB/Swiss-Prot
KEGG Report rno:313387 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108773 IMAGE-MGC_LOAD
NCBI Gene 313387 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 UniProtKB/Swiss-Prot
Pfam UCH UniProtKB/Swiss-Prot
PhenoGen Usp1 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot
  USP_2 UniProtKB/Swiss-Prot
  USP_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007890 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot
UniProt A0ABK0LE09_RAT UniProtKB/TrEMBL
  A6JRL1 ENTREZGENE, UniProtKB/TrEMBL
  A6JRL2 ENTREZGENE, UniProtKB/TrEMBL
  Q569C3 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-12-15 Usp1  ubiquitin specific peptidase 1  Usp1  ubiquitin specific peptdiase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Usp1  ubiquitin specific peptdiase 1    ubiquitin specific protease 1  Name updated 1299863 APPROVED
2005-12-06 Usp1  ubiquitin specific protease 1  Usp1_predicted  ubiquitin specific protease 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Usp1_predicted  ubiquitin specific protease 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED