Sp140 (SP140 nuclear body protein) - Rat Genome Database

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Gene: Sp140 (SP140 nuclear body protein) Rattus norvegicus
Analyze
Symbol: Sp140
Name: SP140 nuclear body protein
RGD ID: 1306355
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. Orthologous to several human genes including SP140 (SP140 nuclear body protein); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 4,4'-diaminodiphenylmethane; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100911733; LOC316580; nuclear body protein SP140; nuclear body protein SP140-like
RGD Orthologs
Human
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8993,672,536 - 93,722,596 (+)NCBIGRCr8
mRatBN7.2986,224,472 - 86,274,724 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,224,513 - 86,274,542 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx994,641,303 - 94,691,604 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0999,769,806 - 99,820,097 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,153,284 - 98,201,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0992,618,088 - 92,665,431 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl992,618,352 - 92,665,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0992,348,882 - 92,396,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4984,281,385 - 84,337,123 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1984,464,803 - 84,520,539 (+)NCBI
Celera983,648,285 - 83,698,110 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
fibrillar center  (ISO)
mitochondrion  (ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Sp140
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8993,672,536 - 93,722,596 (+)NCBIGRCr8
mRatBN7.2986,224,472 - 86,274,724 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,224,513 - 86,274,542 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx994,641,303 - 94,691,604 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0999,769,806 - 99,820,097 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,153,284 - 98,201,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0992,618,088 - 92,665,431 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl992,618,352 - 92,665,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0992,348,882 - 92,396,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4984,281,385 - 84,337,123 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1984,464,803 - 84,520,539 (+)NCBI
Celera983,648,285 - 83,698,110 (+)NCBICelera
Cytogenetic Map9q35NCBI
SP140
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,186,151 - 230,316,571 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,203,110 - 230,313,215 (+)EnsemblGRCh38hg38GRCh38
GRCh372231,090,451 - 231,177,930 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,798,690 - 230,886,174 (+)NCBINCBI36Build 36hg18NCBI36
Build 342230,915,950 - 231,003,435NCBI
Celera2224,866,569 - 224,954,088 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2222,930,492 - 223,018,082 (+)NCBIHuRef
CHM1_12231,096,298 - 231,183,775 (+)NCBICHM1_1
T2T-CHM13v2.02230,669,263 - 230,808,985 (+)NCBIT2T-CHM13v2.0
Sp140
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554534,864,812 - 4,911,699 (-)NCBIChiLan1.0ChiLan1.0
SP140
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213132,852,833 - 132,940,201 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B132,867,800 - 132,955,168 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B117,477,923 - 117,565,367 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B236,279,460 - 236,366,845 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B236,279,460 - 236,366,314 (+)Ensemblpanpan1.1panPan2
SP140
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12542,459,013 - 42,527,141 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2542,459,084 - 42,527,093 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2543,084,192 - 43,152,219 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02542,715,375 - 42,783,760 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12542,645,381 - 42,713,671 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02542,487,182 - 42,555,546 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02542,642,643 - 42,710,911 (+)NCBIUU_Cfam_GSD_1.0
Sp140
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303184,622,858 - 184,700,199 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365256,239,566 - 6,301,657 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP140
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15131,226,626 - 131,292,170 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115131,225,305 - 131,292,172 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215144,909,155 - 144,973,600 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103218035
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110116,260,787 - 116,359,406 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10116,262,327 - 116,349,173 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604083,119,624 - 83,198,605 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Sp140
425 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:191
Count of miRNA genes:123
Interacting mature miRNAs:128
Transcripts:ENSRNOT00000034603
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat

Markers in Region
stSG629967  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2986,253,706 - 86,254,208 (+)MAPPERmRatBN7.2
Rnor_6.0992,644,446 - 92,644,947NCBIRnor6.0
Rnor_5.0992,375,240 - 92,375,741UniSTSRnor5.0
RGSC_v3.4984,315,748 - 84,316,249UniSTSRGSC3.4
Celera983,677,291 - 83,677,792UniSTS
Cytogenetic Map9q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 35 19 19 19 23 23 11
Low 17 22 22 22 8 11 74 12 18 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC081971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000034603   ⟹   ENSRNOP00000031057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,224,513 - 86,274,542 (+)Ensembl
Rnor_6.0 Ensembl992,618,352 - 92,665,430 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078987   ⟹   ENSRNOP00000071192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,230,294 - 86,274,542 (+)Ensembl
Rnor_6.0 Ensembl992,618,550 - 92,665,080 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl990,930,880 - 90,938,099 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110179   ⟹   ENSRNOP00000096593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,224,513 - 86,274,542 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119511   ⟹   ENSRNOP00000080361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,224,513 - 86,274,542 (+)Ensembl
RefSeq Acc Id: NM_001012133   ⟹   NP_001012133
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,582 - 93,722,596 (+)NCBI
mRatBN7.2986,224,513 - 86,274,545 (+)NCBI
Rnor_6.0992,618,088 - 92,665,431 (+)NCBI
Rnor_5.0992,348,882 - 92,396,017 (+)NCBI
RGSC_v3.4984,281,385 - 84,337,123 (+)RGD
Celera983,648,285 - 83,698,110 (+)RGD
Sequence:
RefSeq Acc Id: XM_039083714   ⟹   XP_038939642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
mRatBN7.2986,224,474 - 86,274,724 (+)NCBI
RefSeq Acc Id: XM_039083715   ⟹   XP_038939643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,673,347 - 93,722,596 (+)NCBI
mRatBN7.2986,225,279 - 86,274,545 (+)NCBI
RefSeq Acc Id: XM_039083716   ⟹   XP_038939644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
mRatBN7.2986,224,474 - 86,274,724 (+)NCBI
RefSeq Acc Id: XM_039083717   ⟹   XP_038939645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
mRatBN7.2986,224,474 - 86,274,724 (+)NCBI
RefSeq Acc Id: XM_039083718   ⟹   XP_038939646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
mRatBN7.2986,224,473 - 86,274,724 (+)NCBI
RefSeq Acc Id: XM_039083719   ⟹   XP_038939647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
mRatBN7.2986,224,474 - 86,274,724 (+)NCBI
RefSeq Acc Id: XM_039083722   ⟹   XP_038939650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
mRatBN7.2986,224,474 - 86,274,724 (+)NCBI
RefSeq Acc Id: XM_039083724   ⟹   XP_038939652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,717,307 (+)NCBI
mRatBN7.2986,224,472 - 86,266,494 (+)NCBI
RefSeq Acc Id: XM_063267282   ⟹   XP_063123352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267283   ⟹   XP_063123353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267284   ⟹   XP_063123354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267285   ⟹   XP_063123355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267286   ⟹   XP_063123356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267287   ⟹   XP_063123357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267288   ⟹   XP_063123358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267289   ⟹   XP_063123359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267290   ⟹   XP_063123360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267291   ⟹   XP_063123361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,722,596 (+)NCBI
RefSeq Acc Id: XM_063267292   ⟹   XP_063123362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,717,307 (+)NCBI
RefSeq Acc Id: XR_010054606
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,719,376 (+)NCBI
RefSeq Acc Id: XR_010054607
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8993,672,536 - 93,719,376 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001012133   ⟸   NM_001012133
- UniProtKB: Q66H87 (UniProtKB/TrEMBL),   F7EWA3 (UniProtKB/TrEMBL),   A0A0G2JZU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000031057   ⟸   ENSRNOT00000034603
RefSeq Acc Id: ENSRNOP00000071192   ⟸   ENSRNOT00000078987
RefSeq Acc Id: XP_038939652   ⟸   XM_039083724
- Peptide Label: isoform X18
RefSeq Acc Id: XP_038939646   ⟸   XM_039083718
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939642   ⟸   XM_039083714
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939644   ⟸   XM_039083716
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939645   ⟸   XM_039083717
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939647   ⟸   XM_039083719
- Peptide Label: isoform X9
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939650   ⟸   XM_039083722
- Peptide Label: isoform X12
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939643   ⟸   XM_039083715
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JZU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080361   ⟸   ENSRNOT00000119511
RefSeq Acc Id: ENSRNOP00000096593   ⟸   ENSRNOT00000110179
RefSeq Acc Id: XP_063123353   ⟸   XM_063267283
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZPF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123354   ⟸   XM_063267284
- Peptide Label: isoform X8
- UniProtKB: A0A8I6APK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123352   ⟸   XM_063267282
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063123356   ⟸   XM_063267286
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063123357   ⟸   XM_063267287
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063123359   ⟸   XM_063267289
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063123358   ⟸   XM_063267288
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063123361   ⟸   XM_063267291
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063123355   ⟸   XM_063267285
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063123360   ⟸   XM_063267290
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063123362   ⟸   XM_063267292
- Peptide Label: isoform X19
Protein Domains
Bromo   HSR   PHD-type   SAND

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZU7-F1-model_v2 AlphaFold A0A0G2JZU7 1-719 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696815
Promoter ID:EPDNEW_R7339
Type:multiple initiation site
Name:Sp140_1
Description:SP140 nuclear body protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0992,618,427 - 92,618,487EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306355 AgrOrtholog
BioCyc Gene G2FUF-26941 BioCyc
Ensembl Genes ENSRNOG00000022800 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000059666 Ensembl
Ensembl Transcript ENSRNOT00000034603 ENTREZGENE
  ENSRNOT00000034603.7 UniProtKB/TrEMBL
  ENSRNOT00000078987.2 UniProtKB/TrEMBL
  ENSRNOT00000110179.1 UniProtKB/TrEMBL
  ENSRNOT00000119511.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.10.390.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125855 IMAGE-MGC_LOAD
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  SAND_dom UniProtKB/TrEMBL
  SAND_dom-like UniProtKB/TrEMBL
  Sp100 UniProtKB/TrEMBL
  Sp110/Sp140/Sp140L UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:316580 UniProtKB/TrEMBL
MGC_CLONE MGC:94109 IMAGE-MGC_LOAD
NCBI Gene 316580 ENTREZGENE
PANTHER NUCLEAR BODY PROTEIN SP140 UniProtKB/TrEMBL
  PTHR46386 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
  Sp100 UniProtKB/TrEMBL
PhenoGen Sp140 PhenoGen
PROSITE BROMODOMAIN_2 UniProtKB/TrEMBL
  HSR UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022800 RatGTEx
  ENSRNOG00000059666 RatGTEx
SMART BROMO UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  SAND UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
  FYVE_PHD_ZnF UniProtKB/TrEMBL
  SAND_like UniProtKB/TrEMBL
UniProt A0A0G2JZU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APK4 ENTREZGENE, UniProtKB/TrEMBL
  F7EWA3 ENTREZGENE
  Q66H87 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7EWA3 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Sp140  SP140 nuclear body protein  LOC100911733  nuclear body protein SP140-like  Data merged from RGD:6491475 737654 PROVISIONAL
2012-07-05 LOC100911733  nuclear body protein SP140-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Sp140  SP140 nuclear body protein  Sp140_predicted  SP140 nuclear body protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sp140_predicted  SP140 nuclear body protein (predicted)      Symbol and Name status set to approved 70820 APPROVED