Advanced Search (OLGA)

Gene: Rnd1 (Rho family GTPase 1) Rattus norvegicus

Analyze

Symbol:

Rnd1

Name:

Rho family GTPase 1

RGD ID:

1306338

Description:

Predicted to enable several functions, including GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin filament organization; neuron remodeling; and regulation of actin cytoskeleton organization. Predicted to be located in adherens junction. Predicted to be active in cytosol and plasma membrane. Orthologous to human RND1 (Rho family GTPase 1); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

MGC109441; rho-related GTP-binding protein Rho6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RND1 (Rho family GTPase 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Rnd1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnd1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RND1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RND1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnd1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RND1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RND1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnd1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rnd1 (Rho family GTPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RND1 (Rho family GTPase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnd1 (Rho family GTPase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnd1b (Rho family GTPase 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnd1b (Rho family GTPase 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	rnd1a (Rho family GTPase 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RHO2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	RHO3	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	RHO4	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	rnd1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,700,321 - 131,707,392 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,700,321 - 131,707,392 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,821,311 - 129,828,385 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,821,311 - 129,828,399 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,628,549 - 131,635,626 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,854,095 - 133,861,172 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,766,597 - 133,773,674 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,349,138 - 140,356,209 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,349,138 - 140,356,209 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	114,852,416 - 114,859,487 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,418,519 - 137,425,590 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,311,539 - 126,318,610 (-)	NCBI		Celera
RGSC_v3.1	7	137,494,955 - 137,502,027 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

1-naphthyl isothiocyanate (EXP)

15-acetyldeoxynivalenol (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,4-dinitrotoluene (EXP)

2-amino-2-deoxy-D-glucopyranose (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-aminophenol (EXP)

4-hydroxynon-2-enal (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (ISO)

acetaldehyde (ISO)

acetamide (EXP)

acrylamide (ISO)

afimoxifene (ISO)

aflatoxin B1 (EXP,ISO)

aldehydo-D-glucosamine (ISO)

all-trans-retinoic acid (EXP)

Allylamine (EXP)

alpha-Zearalanol (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

beta-D-glucosamine (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

Butylbenzyl phthalate (EXP)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbofuran (EXP)

carbon nanotube (ISO)

cefaloridine (EXP)

chloroform (EXP)

chloroprene (EXP,ISO)

chlorpromazine (EXP)

chlorpyrifos (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clothianidin (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

cyclophosphamide (EXP)

cyclosporin A (EXP,ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (EXP)

diclofenac (ISO)

dioxygen (EXP,ISO)

dorsomorphin (ISO)

doxorubicin (EXP)

elemental selenium (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenofibrate (EXP)

fenvalerate (EXP)

fluoranthene (ISO)

formaldehyde (ISO)

furan (ISO)

gardiquimod (ISO)

isoprenaline (EXP)

leflunomide (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

maneb (ISO)

metaproterenol (EXP)

metformin (EXP)

methapyrilene (EXP)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

mitoxantrone (EXP)

Moniliformin (ISO)

mono(2-ethylhexyl) phthalate (EXP)

N-methyl-4-phenylpyridinium (ISO)

N-Nitrosopyrrolidine (ISO)

nickel dichloride (EXP)

okadaic acid (ISO)

orciprenaline (EXP)

orphenadrine (EXP)

oxaliplatin (EXP)

paracetamol (ISO)

paraquat (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

phenylbutazone (EXP)

phenylephrine (EXP)

phenytoin (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

protein kinase inhibitor (ISO)

quercetin (ISO)

resorcinol (ISO)

resveratrol (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

tebuconazole (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (EXP,ISO)

topotecan (EXP)

triamterene (EXP)

trichostatin A (ISO)

triptonide (ISO)

troglitazone (EXP)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament organization (IBA,ISO)

negative regulation of cell adhesion (ISO)

neuron remodeling (ISO)

regulation of actin cytoskeleton organization (IBA)

signal transduction (IBA)

small GTPase-mediated signal transduction (IEA)

Cellular Component

actin cytoskeleton (ISO)

adherens junction (ISO)

cytoskeleton (IEA)

cytosol (IBA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

GTP binding (IBA,IEA)

GTPase activity (IBA,IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase binding (IBA)

signaling receptor binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	A role of Rnd1 GTPase in dendritic spine formation in hippocampal neurons.	Ishikawa Y, etal., J Neurosci 2003 Dec 3;23(35):11065-72.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:9531558	PMID:11095956	PMID:14732713	PMID:15738000	PMID:16311049	PMID:16530331	PMID:18996843	PMID:19843518	PMID:24690281	PMID:30797814

Genomics

Comparative Map Data

Rnd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,700,321 - 131,707,392 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,700,321 - 131,707,392 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,821,311 - 129,828,385 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,821,311 - 129,828,399 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,628,549 - 131,635,626 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,854,095 - 133,861,172 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,766,597 - 133,773,674 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,349,138 - 140,356,209 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,349,138 - 140,356,209 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	114,852,416 - 114,859,487 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,418,519 - 137,425,590 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,311,539 - 126,318,610 (-)	NCBI		Celera
RGSC_v3.1	7	137,494,955 - 137,502,027 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

RND1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,857,145 - 48,865,870 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,857,145 - 48,865,870 (-)	Ensembl			hg38	GRCh38
GRCh37	12	49,250,928 - 49,259,653 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,537,197 - 47,545,920 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	47,537,195 - 47,545,920	NCBI
Celera	12	48,047,029 - 48,055,768 (-)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	46,283,762 - 46,292,501 (-)	NCBI		HuRef
CHM1_1	12	49,216,723 - 49,225,496 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,819,339 - 48,828,069 (-)	NCBI		T2T-CHM13v2.0

Rnd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,567,086 - 98,575,342 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,561,302 - 98,575,342 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	98,669,205 - 98,677,461 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,663,421 - 98,677,461 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	98,499,636 - 98,507,892 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,497,239 - 98,505,495 (-)	NCBI		MGSCv36	mm8
Celera	15	100,817,493 - 100,825,752 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.65	NCBI

Rnd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	7,704,298 - 7,709,245 (-)	Ensembl
ChiLan1.0	NW_004955500	7,703,461 - 7,709,363 (-)	NCBI	ChiLan1.0	ChiLan1.0

RND1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,316,380 - 45,325,263 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,313,144 - 45,322,025 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	39,882,076 - 39,890,797 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	40,760,706 - 40,769,407 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	40,760,706 - 40,769,401 (+)	Ensembl			panPan2	panpan1.1

RND1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	5,679,629 - 5,686,657 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	5,679,658 - 5,687,428 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	40,571,242 - 40,578,154 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	5,730,560 - 5,737,493 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	5,730,577 - 5,738,263 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	5,694,470 - 5,701,401 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	5,684,537 - 5,691,454 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	40,963,520 - 40,970,441 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rnd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	66,470,975 - 66,478,988 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	6,685,840 - 6,693,748 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	6,685,855 - 6,693,715 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RND1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	14,914,645 - 14,922,038 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	14,914,652 - 14,922,032 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	15,325,808 - 15,333,219 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RND1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	45,097,166 - 45,106,692 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	45,097,076 - 45,106,187 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	201,040,582 - 201,049,443 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	3,305,677 - 3,313,578 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624816	3,305,907 - 3,312,618 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rnd1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	271,495,776 - 271,502,183 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rnd1
39 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	219
Count of miRNA genes:	146
Interacting mature miRNAs:	180
Transcripts:	ENSRNOT00000018276
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	121393075	137014596	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	119280025	135560836	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	115313999	136544683	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	116269196	132020414	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

RH141940

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	131,700,466 - 131,700,648 (+)	Marker Load Pipeline
mRatBN7.2	7	129,821,456 - 129,821,639 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	140,349,284 - 140,349,465	NCBI	Rnor6.0
Rnor_5.0	X	114,852,562 - 114,852,743	UniSTS	Rnor5.0
RGSC_v3.4	7	137,418,665 - 137,418,846	UniSTS	RGSC3.4
Celera	7	126,311,685 - 126,311,866	UniSTS
RH 3.4 Map	7	1087.3	UniSTS
Cytogenetic Map	7	q36	UniSTS

BE119113

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	129,823,020 - 129,823,179 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	140,350,847 - 140,351,005	NCBI	Rnor6.0
Rnor_5.0	X	114,854,125 - 114,854,283	UniSTS	Rnor5.0
RGSC_v3.4	7	137,420,228 - 137,420,386	UniSTS	RGSC3.4
Celera	7	126,313,248 - 126,313,406	UniSTS
RH 3.4 Map	7	1086.5	UniSTS
Cytogenetic Map	7	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	160	91	90	59	79	59	6	342	178	11	137	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000077856 ⟹ ENSRNOP00000070395

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,700,321 - 131,707,392 (-)	Ensembl
mRatBN7.2 Ensembl	7	129,821,313 - 129,828,398 (-)	Ensembl
Rnor_6.0 Ensembl	7	140,349,138 - 140,356,209 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109910 ⟹ ENSRNOP00000095432

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,702,600 - 131,707,392 (-)	Ensembl
mRatBN7.2 Ensembl	7	129,823,591 - 129,828,399 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113005 ⟹ ENSRNOP00000078280

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,700,321 - 131,707,020 (-)	Ensembl
mRatBN7.2 Ensembl	7	129,821,311 - 129,827,983 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000148045 ⟹ ENSRNOP00000100163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,700,321 - 131,706,261 (-)	Ensembl

RefSeq Acc Id:

NM_001013222 ⟹ NP_001013240

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,700,321 - 131,707,392 (-)	NCBI
mRatBN7.2	7	129,821,311 - 129,828,385 (-)	NCBI
Rnor_6.0	7	140,349,138 - 140,356,209 (-)	NCBI
Rnor_5.0	X	114,852,416 - 114,859,487 (-)	NCBI
RGSC_v3.4	7	137,418,519 - 137,425,590 (-)	RGD
Celera	7	126,311,539 - 126,318,610 (-)	RGD

Sequence:

show sequence

CAGGGAACCGGCAACTAGGCACCAGTGTGGACGCTTGAGGGGCGACCTCCTCCTCACTGAACCC
GAGTCCACGTCCCTCCTAGGCTGCAGCCATGAAGGAGAGACGGACACCGCAGCCAGTGGTGGTC
AGATGTAAGCTTGTGCTGGTGGGGGACGTGCAGTGTGGGAAGACGGCGATGTTACAGGTGCTAG
CGAAAGACTGCTATCCCGAGACCTATGTGCCTACCGTGTTTGAGAATTACACAGCCTGTTTGGA
GACAGAGGAACAGAGAGTGGAGCTTAGTCTCTGGGATACCTCAGGCTCTCCGTACTATGACAAT
GTCCGTCCACTCTGCTACAGCGACTCGGATGCAGTGTTGCTCTGCTTCGACATCAGCCGTCCAG
AGACGATGGACAGTGCACTCAAGAAGTGGAGAACAGAAATCCTAGACTATTGTCCCAGCACACG
TGTTTTGCTTATTGGCTGCAAGACAGATCTTCGAACAGACCTGAGCACTCTAATGGAACTGTCC
CACCAGAAGCAGGCACCCATCTCCTACGAGCAGGGCTGTGCGATAGCCAAGCAGTTGGGTGCAG
AGATCTACCTGGAGGGCTCAGCTTTCACCTCGGAGACGAGCATCCACAGCATCTTCCGGACGGC
ATCCATGGTGTGTCTGAACAAGCCTAGCCCAGTGCCCCCGAAGAGCCCTGTCCGAAGCCTCTCC
AAGCGACTACTCCACCTTCCCAGTCGCTCTGAACTCATCACTTCTACCTTCAAGAAGGAGAAGG
CCAAAAGCTGTTCTATCATGTGAAGTTGGAGCCGGAGGCGGGGAAGACAGCCCCCCACTTCCTC
CCTTGGGGTACAGAGGCATGGGGAGAGGGAGGATGAGACGTTTTCAGATGGCCACGGAGAGAGG
GCTTTAGAAGGAGACAGGAATGGTATTGAAGAAGAGGCCAGGCCTGGCAGGAGGGCCTGACATT
TAAGTGAGGGCCATCATATCCCAAGCCAGGCGCTAGGCTGGAGAGGGGGTCATTGCCCCAGTGT
CCCCCCTACTCCAGAGGAAGGATGGGTACTGGGGAGATGGGGACATGATGGACTCATCTTCAGC
ATCAAGCCTCTTCCGCACATCGTTCCCACACAGGCTCGGGTGGGAGGGGTCCTTGGTCCCCTCT
CTTCCCCTTTACGAAGTGGCAGTGGACTGGAGAGTAGGAAAACCTGGAGGCAGCTCCCTTGGGG
GCTTAACCCAGATGATGCTTCCTCACTGAAACCAGGAGGGCGAGGGCTGACCAGGCCTAAAAAG
GAGACCTCATCTTTGCATAGCCCATGCATCATGGAGAGGTGACATCACACATTCACACGCTTCT
CACTGAAGTCCCCCGGGCCCAAGGGAGAAGCCCCAGACCCCCTTCTTTTGCAGAATGTGGGGGT
GGTGGTGCTGCAGGGGCAGGACTGATGGGGGGGGGGTCGTCACCAGACTTTCCTGCCCTCAGGG
CAGTACAGCTGGGATTTGTTTTATAGACTCTTGTTTTTGGAACTGGGGGGGTGGAGGGGGAGCG
CTTCGATCCGTTATATGTTCTGTGTTTAAAGAAGAAAACCTATTTATTAATGAAATATAACATA
TGAAGAGGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013240	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89994	(Get FASTA)	NCBI Sequence Viewer
	EDL87044	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000070395
	ENSRNOP00000070395.1
	ENSRNOP00000078280.1
	ENSRNOP00000095432.1
	ENSRNOP00000100163.1

RefSeq Acc Id:

NP_001013240 ⟸ NM_001013222

- UniProtKB:

Q5FVG9 (UniProtKB/TrEMBL), A0A0G2JXT4 (UniProtKB/TrEMBL), A0A8I5ZL07 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKERRTPQPVVVRCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELS
LWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTD
LRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKPS
PVPPKSPVRSLSKRLLHLPSRSELITSTFKKEKAKSCSIM

hide sequence

Ensembl Acc Id:

ENSRNOP00000070395 ⟸ ENSRNOT00000077856

Ensembl Acc Id:

ENSRNOP00000078280 ⟸ ENSRNOT00000113005

Ensembl Acc Id:

ENSRNOP00000095432 ⟸ ENSRNOT00000109910

Ensembl Acc Id:

ENSRNOP00000100163 ⟸ ENSRNOT00000148045

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVG9-F1-model_v2	AlphaFold	Q5FVG9	1-232	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695629

Promoter ID:

EPDNEW_R6154

Type:

single initiation site

Name:

Rnd1_1

Description:

Rho family GTPase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	140,356,222 - 140,356,282	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306338	AgrOrtholog
BioCyc Gene	G2FUF-32122	BioCyc
Ensembl Genes	ENSRNOG00000059857	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000077856	ENTREZGENE
	ENSRNOT00000077856.3	UniProtKB/TrEMBL
	ENSRNOT00000109910.2	UniProtKB/TrEMBL
	ENSRNOT00000113005.2	UniProtKB/TrEMBL
	ENSRNOT00000148045.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7320068	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Ras_GTPase	UniProtKB/TrEMBL
	Small_GTP_bd	UniProtKB/TrEMBL
	Small_GTPase_Rho	UniProtKB/TrEMBL
KEGG Report	rno:362993	UniProtKB/TrEMBL
MGC_CLONE	MGC:109441	IMAGE-MGC_LOAD
NCBI Gene	362993	ENTREZGENE
PANTHER	PTHR24072	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PhenoGen	Rnd1	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000059857	RatGTEx
SMART	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0G2JXT4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZL07	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ALF2_RAT	UniProtKB/TrEMBL
	A0ABK0L6G2_RAT	UniProtKB/TrEMBL
	Q5FVG9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Rnd1	Rho family GTPase 1	Rnd1_predicted	Rho family GTPase 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Rnd1_predicted	Rho family GTPase 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message