Hacd2 (3-hydroxyacyl-CoA dehydratase 2) - Rat Genome Database

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Gene: Hacd2 (3-hydroxyacyl-CoA dehydratase 2) Rattus norvegicus
Analyze
Symbol: Hacd2
Name: 3-hydroxyacyl-CoA dehydratase 2
RGD ID: 1306337
Description: Predicted to enable enzyme binding activity and very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity. Predicted to be involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human HACD2 (3-hydroxyacyl-CoA dehydratase 2); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; buspirone.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102551408; LOC288058; protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b; protein-tyrosine phosphatase-like member B; Ptplb; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2-like; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,175,470 - 79,268,975 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1179,175,482 - 79,268,126 (-)EnsemblGRCr8
mRatBN7.21165,667,671 - 65,762,903 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1165,670,281 - 65,762,889 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1174,493,218 - 74,584,605 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,155,521 - 67,247,060 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,186,803 - 66,277,005 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,985,497 - 68,990,023 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,894,445 - 68,989,988 (-)Ensemblrn6Rnor6.0
Rnor_5.01171,984,627 - 72,076,335 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41167,489,819 - 67,581,576 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1165,126,730 - 65,218,607 (-)NCBICelera
RGSC_v3.11167,547,407 - 67,639,377 (-)NCBI
Cytogenetic Map11q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
buspirone  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clothianidin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
L-methionine  (ISO)
mercury dichloride  (ISO)
methylseleninic acid  (ISO)
monosodium L-glutamate  (ISO)
nickel atom  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15024066   PMID:15632090   PMID:18554506  


Genomics

Comparative Map Data
Hacd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,175,470 - 79,268,975 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1179,175,482 - 79,268,126 (-)EnsemblGRCr8
mRatBN7.21165,667,671 - 65,762,903 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1165,670,281 - 65,762,889 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1174,493,218 - 74,584,605 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,155,521 - 67,247,060 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,186,803 - 66,277,005 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,985,497 - 68,990,023 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,894,445 - 68,989,988 (-)Ensemblrn6Rnor6.0
Rnor_5.01171,984,627 - 72,076,335 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41167,489,819 - 67,581,576 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1165,126,730 - 65,218,607 (-)NCBICelera
RGSC_v3.11167,547,407 - 67,639,377 (-)NCBI
Cytogenetic Map11q22NCBI
HACD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383123,491,554 - 123,585,053 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3123,490,820 - 123,585,081 (-)Ensemblhg38GRCh38
GRCh373123,210,401 - 123,303,900 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363124,693,091 - 124,786,726 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3121,620,589 - 121,710,855 (-)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3120,585,854 - 120,675,943 (-)NCBIHuRef
CHM1_13123,176,722 - 123,266,949 (-)NCBICHM1_1
T2T-CHM13v2.03126,211,843 - 126,305,184 (-)NCBIT2T-CHM13v2.0
Hacd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391634,842,791 - 34,929,560 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1634,842,798 - 34,929,547 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381635,022,421 - 35,109,190 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,022,428 - 35,109,177 (+)Ensemblmm10GRCm38
MGSCv371635,022,507 - 35,109,261 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361634,942,168 - 35,028,922 (+)NCBIMGSCv36mm8
Celera1635,490,337 - 35,577,166 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.54NCBI
Hacd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542722,642,478 - 22,734,271 (-)Ensembl
ChiLan1.0NW_00495542722,642,509 - 22,733,170 (-)NCBIChiLan1.0ChiLan1.0
HACD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,444,788 - 121,541,033 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,449,561 - 121,545,414 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03120,588,195 - 120,684,177 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13127,489,213 - 127,584,408 (-)NCBIPanPan1.1PanPan1.1panPan2
HACD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13326,530,221 - 26,643,477 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3326,533,114 - 26,637,035 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3326,552,163 - 26,662,964 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03326,763,562 - 26,874,428 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3326,763,600 - 26,874,550 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13326,558,486 - 26,669,848 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03326,603,816 - 26,714,547 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03327,214,911 - 27,326,501 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hacd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602127,706,184 - 127,796,663 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367251,614,622 - 1,705,132 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367251,614,637 - 1,705,111 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HACD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13136,834,115 - 136,933,549 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113136,834,103 - 136,933,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213146,240,168 - 146,258,854 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HACD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12257,285,948 - 57,379,894 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2257,322,657 - 57,381,683 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041108,966,635 - 109,066,981 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hacd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249121,814,906 - 1,917,009 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249121,814,906 - 1,916,584 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hacd2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1419,796,150 - 19,887,224 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hacd2
849 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:24
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000003013
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
BF396268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21165,688,706 - 65,688,955 (+)MAPPERmRatBN7.2
Rnor_6.01168,912,480 - 68,912,728NCBIRnor6.0
Rnor_5.01172,003,423 - 72,003,671UniSTSRnor5.0
RGSC_v3.41167,508,269 - 67,508,517UniSTSRGSC3.4
Celera1165,146,754 - 65,147,002UniSTS
RH 3.4 Map11438.1UniSTS
Cytogenetic Map11q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003013   ⟹   ENSRNOP00000003013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,175,810 - 79,268,126 (-)Ensembl
mRatBN7.2 Ensembl1165,670,281 - 65,762,889 (-)Ensembl
Rnor_6.0 Ensembl1168,894,445 - 68,989,988 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126686   ⟹   ENSRNOP00000104716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1179,175,482 - 79,268,126 (-)Ensembl
RefSeq Acc Id: NM_001402103   ⟹   NP_001389032
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,175,470 - 79,268,126 (-)NCBI
mRatBN7.21165,670,228 - 65,762,889 (-)NCBI
RefSeq Acc Id: NR_175003
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,175,470 - 79,268,126 (-)NCBI
mRatBN7.21165,670,228 - 65,762,889 (-)NCBI
RefSeq Acc Id: XM_006248439   ⟹   XP_006248501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,175,470 - 79,268,975 (-)NCBI
mRatBN7.21165,667,671 - 65,762,902 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088915   ⟹   XP_038944843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,193,841 - 79,268,975 (-)NCBI
mRatBN7.21165,688,594 - 65,762,903 (-)NCBI
Ensembl Acc Id: ENSRNOP00000003013   ⟸   ENSRNOT00000003013
RefSeq Acc Id: XP_006248501   ⟸   XM_006248439
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_038944843   ⟸   XM_039088915
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001389032   ⟸   NM_001402103
Ensembl Acc Id: ENSRNOP00000104716   ⟸   ENSRNOT00000126686

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHG0-F1-model_v2 AlphaFold D3ZHG0 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698194
Promoter ID:EPDNEW_R8717
Type:initiation region
Name:Hacd2_1
Description:3-hydroxyacyl-CoA dehydratase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01168,990,004 - 68,990,064EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306337 AgrOrtholog
Ensembl Genes ENSRNOG00000038761 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003013 ENTREZGENE
  ENSRNOT00000003013.10 UniProtKB/TrEMBL
  ENSRNOT00000126686 ENTREZGENE
  ENSRNOT00000126686.1 UniProtKB/TrEMBL
InterPro Tyr_Pase-like_PTPLA UniProtKB/TrEMBL
NCBI Gene Hacd2 ENTREZGENE
PANTHER PTHR11035 UniProtKB/TrEMBL
  VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2 UniProtKB/TrEMBL
Pfam PTPLA UniProtKB/TrEMBL
PhenoGen Hacd2 PhenoGen
RatGTEx ENSRNOG00000038761 RatGTEx
UniProt A0ABK0LSF8_RAT UniProtKB/TrEMBL
  D3ZHG0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hacd2  3-hydroxyacyl-CoA dehydratase 2  LOC102551408  very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2-like  Data merged from RGD:7603878 737654 PROVISIONAL
2015-02-04 Hacd2  3-hydroxyacyl-CoA dehydratase 2  Ptplb  protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102551408  very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-05-24 Ptplb  protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b  LOC690040  similar to protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b  Data merged from RGD:1585171 1643240 APPROVED
2008-04-30 Ptplb  protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b   Ptplb_predicted  protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC690040  similar to protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Ptplb_predicted  protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b (predicted)      Symbol and Name status set to approved 70820 APPROVED