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Gene: Ing1 (inhibitor of growth family, member 1) Rattus norvegicus

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Symbol:

Ing1

Name:

inhibitor of growth family, member 1

RGD ID:

1306330

Description:

Predicted to enable histone H3K4me3 reader activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to act upstream of or within protein import into nucleus and regulation of programmed cell death. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma and squamous cell carcinoma. Orthologous to human ING1 (inhibitor of growth family member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

inhibitor of growth protein 1; LOC306626; p33ING1b; p33ING1c

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ING1 (inhibitor of growth family member 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ing1 (inhibitor of growth family, member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ing1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ING1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ING1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ing1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ING1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ING1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ing1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ing1 (inhibitor of growth family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ING1 (inhibitor of growth family member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ing1 (inhibitor of growth family, member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ing1 (inhibitor of growth family, member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PHO23	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	PHO23	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG7379	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG7379	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ing-3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector)
Caenorhabditis elegans (roundworm):	lsy-13	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YNG2	Alliance	DIOPT (InParanoid\|OMA\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	ing1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ing1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	84,639,378 - 84,649,498 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	84,639,381 - 84,647,616 (-)	Ensembl				GRCr8
mRatBN7.2	16	77,937,276 - 77,945,320 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	77,937,279 - 77,946,264 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	83,218,530 - 83,224,410 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	86,671,172 - 86,677,052 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	81,912,593 - 81,918,491 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	83,277,055 - 83,278,120 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	83,276,273 - 83,278,119 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	82,745,096 - 82,746,161 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	82,789,254 - 82,790,319 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	75,737,282 - 75,743,082 (-)	NCBI		Celera
RGSC_v3.1	16	82,740,651 - 82,779,666 (-)	NCBI
Cytogenetic Map	16	q12.5	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

contact dermatitis (ISO)

Disease Progression (ISO)

head and neck squamous cell carcinoma (ISO)

squamous cell carcinoma (ISO)

Stomach Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

all-trans-retinoic acid (ISO)

arsenite(3-) (ISO)

avobenzone (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

Butylbenzyl phthalate (EXP,ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (ISO)

flutamide (EXP)

folic acid (ISO)

glafenine (EXP)

ketoconazole (ISO)

L-methionine (ISO)

lead diacetate (ISO)

methapyrilene (EXP)

methylmercury chloride (ISO)

methylseleninic acid (ISO)

N,N-diethyl-m-toluamide (EXP)

naled (ISO)

nitrates (ISO)

okadaic acid (ISO)

p-menthan-3-ol (ISO)

paracetamol (EXP,ISO)

permethrin (EXP)

rotenone (EXP)

sunitinib (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP)

thiram (ISO)

titanium dioxide (ISO)

Tributyltin oxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

chromatin organization (IEA)

positive regulation of DNA-templated transcription (IBA,ISO)

protein import into nucleus (ISO)

regulation of programmed cell death (ISO)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

histone H3K4me3 reader activity (ISO)

metal ion binding (IEA)

protein binding (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas.	Gunduz M, etal., Cancer Res. 2000 Jun 15;60(12):3143-6.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12054579	PMID:12477932	PMID:16098148	PMID:16728974	PMID:19198660

Genomics

Comparative Map Data

Ing1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	84,639,378 - 84,649,498 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	84,639,381 - 84,647,616 (-)	Ensembl				GRCr8
mRatBN7.2	16	77,937,276 - 77,945,320 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	77,937,279 - 77,946,264 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	83,218,530 - 83,224,410 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	86,671,172 - 86,677,052 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	81,912,593 - 81,918,491 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	83,277,055 - 83,278,120 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	83,276,273 - 83,278,119 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	82,745,096 - 82,746,161 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	82,789,254 - 82,790,319 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	75,737,282 - 75,743,082 (-)	NCBI		Celera
RGSC_v3.1	16	82,740,651 - 82,779,666 (-)	NCBI
Cytogenetic Map	16	q12.5	NCBI

ING1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	110,712,623 - 110,723,339 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	110,712,736 - 110,723,339 (+)	Ensembl			hg38	GRCh38
GRCh37	13	111,364,970 - 111,375,686 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	110,163,084 - 110,171,422 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	13	110,163,625 - 110,171,421	NCBI
Celera	13	92,211,252 - 92,219,600 (+)	NCBI		Celera
Cytogenetic Map	13	q34	NCBI
HuRef	13	91,963,392 - 91,971,853 (+)	NCBI		HuRef
CHM1_1	13	111,333,082 - 111,341,534 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	109,942,828 - 109,953,552 (+)	NCBI		T2T-CHM13v2.0

Ing1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	11,605,762 - 11,613,251 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	11,605,571 - 11,613,251 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	11,555,762 - 11,563,251 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	11,555,571 - 11,563,251 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	11,556,066 - 11,563,250 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	11,556,038 - 11,563,222 (+)	NCBI		MGSCv36	mm8
Celera	8	11,736,119 - 11,737,953 (+)	NCBI		Celera
Cytogenetic Map	8	A1.1	NCBI
cM Map	8	5.73	NCBI

Ing1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	1,998,912 - 1,999,613 (-)	Ensembl
ChiLan1.0	NW_004955404	1,998,665 - 1,999,615 (-)	NCBI	ChiLan1.0	ChiLan1.0

ING1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	112,208,086 - 112,216,613 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	110,890,357 - 110,898,880 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	91,849,153 - 91,856,943 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	110,966,199 - 110,971,831 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	110,963,405 - 110,970,691 (+)	Ensembl			panPan2	panpan1.1

ING1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	58,952,526 - 58,958,063 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	58,946,939 - 58,957,804 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	58,663,817 - 58,669,360 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	59,576,109 - 59,581,650 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	59,576,109 - 59,581,391 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	59,078,248 - 59,083,790 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	59,070,143 - 59,075,694 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	59,106,235 - 59,111,785 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ing1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	193,812,246 - 193,819,522 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936472	2,133,646 - 2,140,047 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936472	2,132,991 - 2,140,343 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ING1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	77,270,320 - 77,277,068 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	11	77,270,272 - 77,278,346 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ING1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	88,935,764 - 88,943,887 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	88,937,297 - 88,943,046 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666046	45,700,604 - 45,708,993 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ing1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624793	2,121,290 - 2,125,598 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624793	2,121,290 - 2,126,573 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ing1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	72,298,088 - 72,305,513 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ing1
50 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	27
Count of miRNA genes:	25
Interacting mature miRNAs:	27
Transcripts:	ENSRNOT00000019454
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	59428714	91442908	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	59428714	91442908	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	59428714	91442908	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat

Markers in Region

AI875420

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	77,937,387 - 77,937,497 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	83,276,384 - 83,276,493	NCBI	Rnor6.0
Rnor_5.0	16	82,744,425 - 82,744,534	UniSTS	Rnor5.0
RGSC_v3.4	16	82,788,583 - 82,788,692	UniSTS	RGSC3.4
Celera	16	75,736,611 - 75,736,720	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

UniSTS:498267

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	77,938,132 - 77,938,754 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	83,277,128 - 83,277,749	NCBI	Rnor6.0
Rnor_5.0	16	82,745,169 - 82,745,790	UniSTS	Rnor5.0
RGSC_v3.4	16	82,789,327 - 82,789,948	UniSTS	RGSC3.4
Celera	16	75,737,355 - 75,737,976	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001038591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY624101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY624102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY624103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY624104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY624105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019454 ⟹ ENSRNOP00000019454

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	84,640,178 - 84,644,436 (-)	Ensembl
mRatBN7.2 Ensembl	16	77,938,077 - 77,942,336 (-)	Ensembl
Rnor_6.0 Ensembl	16	83,276,273 - 83,278,119 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108207 ⟹ ENSRNOP00000079020

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	84,639,520 - 84,647,551 (-)	Ensembl
mRatBN7.2 Ensembl	16	77,937,617 - 77,946,264 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120249 ⟹ ENSRNOP00000079627

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	84,640,178 - 84,641,634 (-)	Ensembl
mRatBN7.2 Ensembl	16	77,937,279 - 77,943,934 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167154 ⟹ ENSRNOP00000112064

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	84,639,520 - 84,647,616 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167372 ⟹ ENSRNOP00000109765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	84,639,381 - 84,646,034 (-)	Ensembl

RefSeq Acc Id:

NM_001038591 ⟹ NP_001033680

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	84,640,161 - 84,646,041 (-)	NCBI
mRatBN7.2	16	77,938,060 - 77,943,941 (-)	NCBI
Rnor_6.0	16	83,277,055 - 83,278,120 (-)	NCBI
Rnor_5.0	16	82,745,096 - 82,746,161 (-)	NCBI
RGSC_v3.4	16	82,789,254 - 82,790,319 (-)	RGD
Celera	16	75,737,282 - 75,743,082 (-)	RGD

Sequence:

show sequence

CGGAAAGCCGCCGAGTCGCCGGGGACCTCCGGGGTGAACCATGTTGAGTCCTGCCAACGGGGAG
CAGATCCACCTGGTGAACTATGTGGAGGATTACCTGGACTCAATCGAGTCACTGCCTTTCGACC
TGCAGAGGAACGTCTCGCTGATGCGGGAGATCGACGCCAAATACCAAGAGATCCTGAAGGAGTT
GGATGACTACTATGAGAAGTTCAAGCGGGAGACGGACAGCACCCAGAAGAGGCGGGTGCTGCAC
TGCATCCAGAGGGCCCTGATCCGAAGCCAGGAGCTGGGCGACGAGAAGATCCAGATCGTGAGTC
AGATGGTGGAGCTGGTGGAGAACCGCAGCAGGCAGGTGGACAGTCATGTAGAGCTCTTCGAAGC
ACACCAGGACATCAGTGATGGCACTGGTGGTGGCGGCAAGGCAGGCCAGGACAAGTCAAAGAGT
GAAGCGATCACACAGGCAGATAAGCCAAATAACAAGCGGTCCCGGAGGCAGCGAAACAACGAGA
ACCGAGAAAACGCCTCGAACAATCACGACCATGACGACATCACCTCAGGAACGCCCAAGGAGAA
GAAAGCAAAAATCTCAAAGAAGAAGAAACGCTCTAAGGCCAAAGCAGAGAGGGAGGCGTCCCCC
GCGGACCTCCCCATCGACCCCAACGAGCCCACGTACTGTCTGTGCAACCAGGTCTCCTATGGAG
AGATGATCGGCTGTGACAACGACGAGTGTCCCATCGAGTGGTTCCACTTTTCTTGTGTGGGACT
CAACCATAAACCAAAGGGCAAGTGGTACTGCCCCAAGTGCCGTGGGGAGAGTGAAAAGACAATG
GACAAGGCCCTGGAGAAGTCCAAGAAAGAGAGGGCTTACAACAGGTAGTTAGCGCACATTTGCC
CACGATCCAGAGTAACAAAACCCACCAGTGTATTTATGATGTCGCTGCCTTTTCGGAAGTATGA
GGACGGTCAGACAAGTGTTTTTATAGAGTGTTAGCAATGGATCCTCTCCTTGGGATGGCGGAGA
CAGCCCGTGTCTTCATGGTATACCTTGTTTCCACACAGGGTCTGCCGGTCAGCAATTTAGAAAC
CACAAATACAGGTCCGAATTAAACGTGTCCACAAGTGTCAGACTGATTTTTGGGGTTGGGGAGT
GACTTGGAAGTAACCTAACATATATAAAGAAGAGATTTAATTTGGCTGTTTTAACAAAAATGTT
ACGGTTTACAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094601 ⟹ XP_038950529

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	84,639,378 - 84,649,498 (-)	NCBI
mRatBN7.2	16	77,937,276 - 77,945,320 (-)	NCBI

RefSeq Acc Id:

XM_039094602 ⟹ XP_038950530

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	84,639,378 - 84,646,004 (-)	NCBI
mRatBN7.2	16	77,937,276 - 77,943,904 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001033680	(Get FASTA)	NCBI Sequence Viewer
	NP_001420850	(Get FASTA)	NCBI Sequence Viewer
	NP_001420851	(Get FASTA)	NCBI Sequence Viewer
	NP_001420852	(Get FASTA)	NCBI Sequence Viewer
	XP_038950529	(Get FASTA)	NCBI Sequence Viewer
	XP_038950530	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86336	(Get FASTA)	NCBI Sequence Viewer
	AAI66594	(Get FASTA)	NCBI Sequence Viewer
	AAV32074	(Get FASTA)	NCBI Sequence Viewer
	AAV32075	(Get FASTA)	NCBI Sequence Viewer
	AAV32076	(Get FASTA)	NCBI Sequence Viewer
	AAV32077	(Get FASTA)	NCBI Sequence Viewer
	AAV32078	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019454.6
	ENSRNOP00000079020.1
	ENSRNOP00000079627
	ENSRNOP00000079627.2
	ENSRNOP00000109765
	ENSRNOP00000109765.1
	ENSRNOP00000112064
	ENSRNOP00000112064.1

RefSeq Acc Id:

NP_001033680 ⟸ NM_001038591

- UniProtKB:

B2GVA7 (UniProtKB/TrEMBL), Q2TSE3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSPANGEQIHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDDYYEKFKRETDS
TQKRRVLHCIQRALIRSQELGDEKIQIVSQMVELVENRSRQVDSHVELFEAHQDISDGTGGGGK
AGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKISKKKKRSKA
KAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKC
RGESEKTMDKALEKSKKERAYNR

hide sequence

Ensembl Acc Id:

ENSRNOP00000019454 ⟸ ENSRNOT00000019454

RefSeq Acc Id:	XP_038950529 ⟸ XM_039094601
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZM05 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038950530 ⟸ XM_039094602
- Peptide Label:	isoform X2
- UniProtKB:	G3V7V1 (UniProtKB/TrEMBL), A6IWP1 (UniProtKB/TrEMBL), Q2TSE1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000079020 ⟸ ENSRNOT00000108207

Ensembl Acc Id:

ENSRNOP00000079627 ⟸ ENSRNOT00000120249

Ensembl Acc Id:

ENSRNOP00000112064 ⟸ ENSRNOT00000167154

Ensembl Acc Id:

ENSRNOP00000109765 ⟸ ENSRNOT00000167372

Protein Domains

PHD-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V7V1-F1-model_v2	AlphaFold	G3V7V1	1-234	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306330	AgrOrtholog
BioCyc Gene	G2FUF-10658	BioCyc
Ensembl Genes	ENSRNOG00000014520	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019454.9	UniProtKB/TrEMBL
	ENSRNOT00000108207.2	UniProtKB/TrEMBL
	ENSRNOT00000120249	ENTREZGENE
	ENSRNOT00000120249.2	UniProtKB/TrEMBL
	ENSRNOT00000167154	ENTREZGENE
	ENSRNOT00000167154.1	UniProtKB/TrEMBL
	ENSRNOT00000167372	ENTREZGENE
	ENSRNOT00000167372.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
	6.10.140.1740	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7301709	IMAGE-MGC_LOAD
	IMAGE:7937717	IMAGE-MGC_LOAD
InterPro	ING1	UniProtKB/TrEMBL
	ING_fam	UniProtKB/TrEMBL
	ING_N	UniProtKB/TrEMBL
	Zinc_finger_PHD-type_CS	UniProtKB/TrEMBL
	Znf_FYVE_PHD	UniProtKB/TrEMBL
	Znf_PHD	UniProtKB/TrEMBL
	Znf_PHD-finger	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
KEGG Report	rno:306626	UniProtKB/TrEMBL
MGC_CLONE	MGC:105941	IMAGE-MGC_LOAD
	MGC:188361	IMAGE-MGC_LOAD
NCBI Gene	306626	ENTREZGENE
PANTHER	PTHR10333	UniProtKB/TrEMBL
	PTHR10333:SF85	UniProtKB/TrEMBL
Pfam	ING	UniProtKB/TrEMBL
	PHD	UniProtKB/TrEMBL
PhenoGen	Ing1	PhenoGen
PROSITE	ZF_PHD_1	UniProtKB/TrEMBL
	ZF_PHD_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014520	RatGTEx
SMART	ING	UniProtKB/TrEMBL
	PHD	UniProtKB/TrEMBL
Superfamily-SCOP	FYVE_PHD_ZnF	UniProtKB/TrEMBL
UniProt	A0A8I5ZM05	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LZG1_RAT	UniProtKB/TrEMBL
	A6IWP1	ENTREZGENE, UniProtKB/TrEMBL
	B2GVA7	ENTREZGENE, UniProtKB/TrEMBL
	G3V7V1	ENTREZGENE, UniProtKB/TrEMBL
	Q2TSE1	ENTREZGENE, UniProtKB/TrEMBL
	Q2TSE3	ENTREZGENE, UniProtKB/TrEMBL
	Q5RK29_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Ing1	inhibitor of growth family, member 1	Ing1_predicted	inhibitor of growth family, member 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ing1_predicted	inhibitor of growth family, member 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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