Tfap2b (transcription factor AP-2 beta) - Rat Genome Database

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Gene: Tfap2b (transcription factor AP-2 beta) Rattus norvegicus
Analyze
Symbol: Tfap2b
Name: transcription factor AP-2 beta
RGD ID: 1306321
Description: Enables chromatin binding activity. Involved in response to xenobiotic stimulus. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Char syndrome and patent ductus arteriosus. Orthologous to human TFAP2B (transcription factor AP-2 beta); INTERACTS WITH 1,2-dimethylhydrazine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301285; Tcfap2b; transcription factor AP-2-beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8929,282,703 - 29,312,568 (+)NCBIGRCr8
mRatBN7.2921,786,251 - 21,816,054 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx930,275,269 - 30,304,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0935,415,401 - 35,444,816 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0933,717,660 - 33,747,055 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0925,410,669 - 25,440,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl925,410,669 - 25,440,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0924,271,604 - 24,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,052,402 - 18,082,202 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1918,049,775 - 18,079,184 (+)NCBI
Celera919,374,332 - 19,403,772 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aorta morphogenesis  (ISO,ISS)
collecting duct development  (ISO,ISS)
distal tubule development  (ISO,ISS)
ductus arteriosus closure  (ISO,ISS)
fat cell differentiation  (ISO)
forelimb morphogenesis  (ISO,ISS)
gene expression  (ISO)
glucose metabolic process  (ISO,ISS)
hindlimb morphogenesis  (ISO,ISS)
kidney development  (ISO,ISS)
metanephric nephron development  (ISO)
negative regulation of apoptotic process  (IBA,ISO,ISS)
negative regulation of cell population proliferation  (ISO,ISS)
negative regulation of DNA-templated transcription  (ISO,ISS)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO,ISS)
nervous system development  (IBA)
neuron apoptotic process  (ISO)
positive regulation of cell population proliferation  (ISO,ISS)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of neuron apoptotic process  (ISO,ISS)
positive regulation of transcription by RNA polymerase II  (IBA,ISO,ISS)
regulation of BMP signaling pathway  (ISO,ISS)
regulation of cell differentiation  (ISO,ISS)
regulation of cell population proliferation  (IBA)
regulation of insulin secretion  (ISO,ISS)
regulation of transcription by RNA polymerase II  (ISO,ISS)
response to xenobiotic stimulus  (IEP)
retina layer formation  (ISO)
sensory organ development  (ISO)
skin development  (ISO)
smooth muscle tissue development  (ISO)
sympathetic nervous system development  (ISO,ISS)
transcription by RNA polymerase II  (ISO)

Cellular Component
nucleus  (IBA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Brainstem levels of transcription factor AP-2 in rat are changed after treatment with phenelzine, but not with citalopram. Berggard C, etal., BMC Pharmacol. 2005 Jan 21;5(1):1.
2. Chronic pharmacological treatment with certain antidepressants alters the expression and DNA-binding activity of transcription factor AP-2. Damberg M, etal., Life Sci. 2000 Dec 29;68(6):669-78.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Transcription factor AP-2beta regulates the neurotransmitter phenotype and maturation of chromaffin cells. Hong SJ, etal., Mol Cell Neurosci. 2011 Jan;46(1):245-51. Epub 2010 Sep 27.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein. Mishra SK, etal., J Biol Chem. 2005 May 13;280(19):19270-80. Epub 2005 Feb 22.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Decrease in the AP-2 DNA-binding activity and in the protein expression of AP-2 alpha and AP-2 beta in frontal cortex of rats treated with lithium for 6 weeks. Rao JS, etal., Neuropsychopharmacology. 2005 Nov;30(11):2006-13.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus. Satoda M, etal., Nat Genet. 2000 May;25(1):42-6.
15. The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes. Tao Y, etal., Endocrinology. 2006 Apr;147(4):1685-96. Epub 2005 Dec 22.
Additional References at PubMed
PMID:7555706   PMID:7559606   PMID:9271117   PMID:11505339   PMID:11694877   PMID:12072434   PMID:12169688   PMID:12695560   PMID:15940393   PMID:16373396   PMID:17525748   PMID:19325541  
PMID:20448150   PMID:20607706   PMID:21539825   PMID:21829553  


Genomics

Comparative Map Data
Tfap2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8929,282,703 - 29,312,568 (+)NCBIGRCr8
mRatBN7.2921,786,251 - 21,816,054 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx930,275,269 - 30,304,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0935,415,401 - 35,444,816 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0933,717,660 - 33,747,055 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0925,410,669 - 25,440,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl925,410,669 - 25,440,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0924,271,604 - 24,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,052,402 - 18,082,202 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1918,049,775 - 18,079,184 (+)NCBI
Celera919,374,332 - 19,403,772 (+)NCBICelera
Cytogenetic Map9q13NCBI
TFAP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38650,818,355 - 50,847,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl650,818,723 - 50,847,619 (+)EnsemblGRCh38hg38GRCh38
GRCh37650,786,584 - 50,815,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36650,894,398 - 50,923,285 (+)NCBINCBI36Build 36hg18NCBI36
Build 34650,894,541 - 50,919,634NCBI
Celera652,342,514 - 52,371,233 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef650,517,924 - 50,546,498 (+)NCBIHuRef
CHM1_1650,789,288 - 50,818,174 (+)NCBICHM1_1
T2T-CHM13v2.0650,660,443 - 50,690,369 (+)NCBIT2T-CHM13v2.0
Tfap2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39119,279,132 - 19,309,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl119,279,138 - 19,308,800 (+)EnsemblGRCm39 Ensembl
GRCm38119,208,908 - 19,238,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,208,914 - 19,238,576 (+)EnsemblGRCm38mm10GRCm38
MGSCv37119,198,995 - 19,228,815 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36119,194,128 - 19,223,948 (+)NCBIMGSCv36mm8
Celera119,103,515 - 19,133,268 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map16.19NCBI
Tfap2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554117,142,607 - 7,170,467 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554117,143,095 - 7,171,285 (-)NCBIChiLan1.0ChiLan1.0
TFAP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2565,292,098 - 65,635,311 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1661,157,412 - 61,512,510 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0650,376,157 - 50,406,740 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1651,635,899 - 51,664,691 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl651,635,899 - 51,664,691 (+)Ensemblpanpan1.1panPan2
TFAP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11218,544,176 - 18,574,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1218,544,446 - 18,572,902 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1218,436,730 - 18,462,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01219,041,005 - 19,071,021 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1219,041,155 - 19,069,637 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11218,549,889 - 18,575,642 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01218,654,100 - 18,679,842 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01218,791,560 - 18,817,345 (+)NCBIUU_Cfam_GSD_1.0
Tfap2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494654,075,431 - 54,104,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364769,857,773 - 9,884,784 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364769,855,992 - 9,884,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFAP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl744,745,827 - 44,770,606 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1744,745,653 - 44,774,563 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2751,206,179 - 51,235,198 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFAP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11721,599,570 - 21,629,757 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1721,604,067 - 21,628,489 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604450,760,129 - 50,788,887 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfap2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248555,355,239 - 5,381,477 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248555,353,347 - 5,381,454 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tfap2b
188 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:739
Count of miRNA genes:290
Interacting mature miRNAs:370
Transcripts:ENSRNOT00000030912
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat

Markers in Region
Tcfap2b  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2921,811,442 - 21,811,921 (+)MAPPERmRatBN7.2
Rnor_6.0925,436,224 - 25,436,702NCBIRnor6.0
Rnor_5.0924,298,653 - 24,299,131UniSTSRnor5.0
RGSC_v3.4918,078,000 - 18,078,478UniSTSRGSC3.4
Celera919,399,570 - 19,400,048UniSTS
Cytogenetic Map9q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 3 25 113 59 57 27 23 27 6 150 68 93 45 57 30

Sequence


Ensembl Acc Id: ENSRNOT00000030912   ⟹   ENSRNOP00000030726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl921,789,325 - 21,811,605 (+)Ensembl
Rnor_6.0 Ensembl925,410,669 - 25,440,384 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090920   ⟹   ENSRNOP00000075514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl921,786,258 - 21,814,520 (+)Ensembl
Rnor_6.0 Ensembl925,410,717 - 25,440,411 (+)Ensembl
RefSeq Acc Id: NM_001106896   ⟹   NP_001100366
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8929,283,003 - 29,312,568 (+)NCBI
mRatBN7.2921,786,485 - 21,816,054 (+)NCBI
Rnor_6.0925,410,669 - 25,440,426 (+)NCBI
Rnor_5.0924,271,604 - 24,302,855 (+)NCBI
RGSC_v3.4918,052,402 - 18,082,202 (+)RGD
Celera919,374,332 - 19,403,772 (+)RGD
Sequence:
RefSeq Acc Id: NM_001413770   ⟹   NP_001400699
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8929,283,003 - 29,312,568 (+)NCBI
mRatBN7.2921,786,485 - 21,816,054 (+)NCBI
RefSeq Acc Id: XM_008766927   ⟹   XP_008765149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8929,282,709 - 29,312,564 (+)NCBI
mRatBN7.2921,786,251 - 21,815,785 (+)NCBI
Rnor_6.0925,410,691 - 25,440,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063266871   ⟹   XP_063122941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8929,282,703 - 29,312,564 (+)NCBI
RefSeq Acc Id: XM_063266872   ⟹   XP_063122942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8929,283,129 - 29,312,564 (+)NCBI
RefSeq Acc Id: XR_010054581
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8929,282,709 - 29,312,564 (+)NCBI
RefSeq Acc Id: NP_001100366   ⟸   NM_001106896
- Peptide Label: isoform 2
- UniProtKB: D4A505 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765149   ⟸   XM_008766927
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000075514   ⟸   ENSRNOT00000090920
Ensembl Acc Id: ENSRNOP00000030726   ⟸   ENSRNOT00000030912
RefSeq Acc Id: NP_001400699   ⟸   NM_001413770
- Peptide Label: isoform 1
- UniProtKB: A0A0G2KAT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122941   ⟸   XM_063266871
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063122942   ⟸   XM_063266872
- Peptide Label: isoform X3
Protein Domains
Transcription factor AP-2 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KAT2-F1-model_v2 AlphaFold A0A0G2KAT2 1-459 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696575
Promoter ID:EPDNEW_R7096
Type:initiation region
Name:Tfap2b_1
Description:transcription factor AP-2 beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0925,410,755 - 25,410,815EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306321 AgrOrtholog
BioCyc Gene G2FUF-28045 BioCyc
Ensembl Genes ENSRNOG00000011823 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030912.5 UniProtKB/TrEMBL
  ENSRNOT00000090920.2 UniProtKB/TrEMBL
InterPro TF_AP2 UniProtKB/TrEMBL
  TF_AP2_beta UniProtKB/TrEMBL
  TF_AP2_C UniProtKB/TrEMBL
NCBI Gene 301285 ENTREZGENE
PANTHER PTHR10812:SF14 UniProtKB/TrEMBL
  TF_AP2 UniProtKB/TrEMBL
Pfam TF_AP-2 UniProtKB/TrEMBL
PhenoGen Tfap2b PhenoGen
PRINTS AP2BTNSCPFCT UniProtKB/TrEMBL
  AP2TNSCPFCT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011823 RatGTEx
UniProt A0A0G2KAT2 ENTREZGENE, UniProtKB/TrEMBL
  D4A505 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-06-09 Tfap2b  transcription factor AP-2 beta  Tcfap2b  transcription factor AP-2 beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tcfap2b  transcription factor AP-2 beta   Tcfap2b_predicted  transcription factor AP-2 beta (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tcfap2b_predicted  transcription factor AP-2 beta (predicted)      Symbol and Name status set to approved 70820 APPROVED