Espl1 (extra spindle pole bodies like 1, separase) - Rat Genome Database

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Gene: Espl1 (extra spindle pole bodies like 1, separase) Rattus norvegicus
Analyze
Symbol: Espl1
Name: extra spindle pole bodies like 1, separase
RGD ID: 1306266
Description: Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in meiotic chromosome separation. Predicted to act upstream of or within homologous chromosome segregation; meiotic spindle organization; and mitotic sister chromatid segregation. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Orthologous to human ESPL1 (extra spindle pole bodies like 1, separase); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle pole bodies homolog 1 (S. cerevisiae); extra spindle poles like 1; extra spindle poles like 1 (S. cerevisiae) ; LOC103690081; LOC315330; separin; separin-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,302,460 - 135,329,570 (+)NCBIGRCr8
mRatBN7.27133,424,027 - 133,450,984 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,424,130 - 133,450,984 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,185,119 - 135,211,984 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,414,499 - 137,441,364 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,399,660 - 137,426,528 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,896,890 - 143,923,868 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,897,014 - 143,923,868 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,692,925 - 141,719,617 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.07143,153,049 - 143,161,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,048,197 - 141,074,383 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,126,857 - 141,150,662 (+)NCBI
Celera7129,857,507 - 129,884,392 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4-hydroxynon-2-enal  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
alpha-amanitin  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bleomycin A2  (ISO)
butanal  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (EXP)
diallyl trisulfide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
Echimidine  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glyphosate  (ISO)
GW 4064  (ISO)
L-methionine  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
lucanthone  (ISO)
methimazole  (EXP)
monocrotaline  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
phytoestrogen  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
resveratrol  (ISO)
riddelliine  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IBA,ISO)
cytoplasm  (IBA)
mitotic spindle  (IBA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12672959   PMID:14561405   PMID:16533945   PMID:19625504   PMID:23975099  


Genomics

Comparative Map Data
Espl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,302,460 - 135,329,570 (+)NCBIGRCr8
mRatBN7.27133,424,027 - 133,450,984 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,424,130 - 133,450,984 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,185,119 - 135,211,984 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,414,499 - 137,441,364 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,399,660 - 137,426,528 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,896,890 - 143,923,868 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,897,014 - 143,923,868 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,692,925 - 141,719,617 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.07143,153,049 - 143,161,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,048,197 - 141,074,383 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,126,857 - 141,150,662 (+)NCBI
Celera7129,857,507 - 129,884,392 (+)NCBICelera
Cytogenetic Map7q36NCBI
ESPL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,268,299 - 53,293,638 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,268,299 - 53,293,638 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,662,083 - 53,687,422 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,948,350 - 51,973,694 (+)NCBINCBI36Build 36hg18NCBI36
Build 341251,948,817 - 51,973,694NCBI
Celera1253,311,187 - 53,336,713 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,703,798 - 50,728,935 (+)NCBIHuRef
CHM1_11253,628,380 - 53,653,869 (+)NCBICHM1_1
T2T-CHM13v2.01253,233,854 - 53,259,351 (+)NCBIT2T-CHM13v2.0
Espl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,204,688 - 102,232,792 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,204,701 - 102,232,792 (+)EnsemblGRCm39 Ensembl
GRCm3815102,296,254 - 102,324,357 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,296,266 - 102,324,357 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,126,724 - 102,154,787 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,124,359 - 102,152,390 (+)NCBIMGSCv36mm8
Celera15104,453,712 - 104,481,413 (+)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.45NCBI
Espl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458530,797 - 553,985 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458530,269 - 553,919 (+)NCBIChiLan1.0ChiLan1.0
ESPL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,892,230 - 40,918,541 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,887,281 - 40,915,313 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,460,500 - 35,486,794 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,241,364 - 36,266,594 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,241,533 - 36,266,101 (-)Ensemblpanpan1.1panPan2
ESPL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,911,179 - 1,934,446 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,911,193 - 1,933,807 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,314,872 - 44,338,083 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,915,651 - 1,938,901 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,915,665 - 1,938,966 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,933,939 - 1,957,164 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,918,870 - 1,942,108 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,715,570 - 44,738,805 (+)NCBIUU_Cfam_GSD_1.0
Espl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,588,213 - 62,619,030 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,556,672 - 10,576,588 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,556,269 - 10,576,582 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESPL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,487,052 - 18,509,913 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,486,969 - 18,509,913 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,922,397 - 18,945,652 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESPL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,374,333 - 49,401,801 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037196,658,194 - 196,684,208 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Espl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,305,000 - 1,330,761 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,305,040 - 1,330,505 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Espl1
102 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:150
Count of miRNA genes:110
Interacting mature miRNAs:133
Transcripts:ENSRNOT00000017314
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
BF407910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,450,688 - 133,450,825 (+)MAPPERmRatBN7.2
Rnor_6.07143,923,573 - 143,923,709NCBIRnor6.0
Rnor_5.07141,719,614 - 141,719,750UniSTSRnor5.0
RGSC_v3.47141,074,380 - 141,074,516UniSTSRGSC3.4
Celera7129,884,097 - 129,884,233UniSTS
RH 3.4 Map71065.0UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017314   ⟹   ENSRNOP00000017314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,424,130 - 133,450,984 (+)Ensembl
Rnor_6.0 Ensembl7143,897,014 - 143,923,868 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107226   ⟹   ENSRNOP00000085163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,424,130 - 133,450,984 (+)Ensembl
RefSeq Acc Id: NM_001170602   ⟹   NP_001164073
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,302,716 - 135,329,570 (+)NCBI
mRatBN7.27133,424,130 - 133,450,984 (+)NCBI
Rnor_6.07143,897,014 - 143,923,868 (+)NCBI
Rnor_5.07143,153,049 - 143,161,944 (+)NCBI
Celera7129,857,507 - 129,884,392 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006242460   ⟹   XP_006242522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,302,460 - 135,329,278 (+)NCBI
mRatBN7.27133,424,027 - 133,450,534 (+)NCBI
Rnor_6.07143,896,890 - 143,923,576 (+)NCBI
Rnor_5.07141,692,925 - 141,719,617 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079346   ⟹   XP_038935274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,302,780 - 135,329,278 (+)NCBI
mRatBN7.27133,424,212 - 133,450,534 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001164073 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242522 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935274 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86850 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017314.6
  ENSRNOP00000085163.1
RefSeq Acc Id: NP_001164073   ⟸   NM_001170602
- UniProtKB: D3ZDT7 (UniProtKB/TrEMBL),   A6KCU2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242522   ⟸   XM_006242460
- Peptide Label: isoform X1
- UniProtKB: D3ZDT7 (UniProtKB/TrEMBL),   A6KCU2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017314   ⟸   ENSRNOT00000017314
RefSeq Acc Id: XP_038935274   ⟸   XM_039079346
- Peptide Label: isoform X1
- UniProtKB: D3ZDT7 (UniProtKB/TrEMBL),   A6KCU2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085163   ⟸   ENSRNOT00000107226
Protein Domains
Peptidase C50

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDT7-F1-model_v2 AlphaFold D3ZDT7 1-2109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306266 AgrOrtholog
BioCyc Gene G2FUF-31942 BioCyc
Ensembl Genes ENSRNOG00000012835 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017314.7 UniProtKB/TrEMBL
  ENSRNOT00000107226.1 UniProtKB/TrEMBL
InterPro Peptidase_C50 UniProtKB/TrEMBL
  SEPARIN_core_dom UniProtKB/TrEMBL
KEGG Report rno:315330 UniProtKB/TrEMBL
NCBI Gene 315330 ENTREZGENE
PANTHER Peptidase_C50 UniProtKB/TrEMBL
  SEPARIN UniProtKB/TrEMBL
Pfam Peptidase_C50 UniProtKB/TrEMBL
PhenoGen Espl1 PhenoGen
PROSITE SEPARIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012835 RatGTEx
UniProt A0A8I6A0R2_RAT UniProtKB/TrEMBL
  A6KCU2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDT7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Espl1  extra spindle pole bodies like 1, separase  LOC103690081  separin-like  Data merged from RGD:9148564 737654 PROVISIONAL
2015-07-09 Espl1  extra spindle pole bodies like 1, separase  Espl1  extra spindle pole bodies 1, separase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-01 Espl1  extra spindle pole bodies 1, separase  Espl1  extra spindle pole bodies homolog 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103690081  separin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-12-15 Espl1  extra spindle pole bodies homolog 1 (S. cerevisiae)  Espl1  extra spindle poles like 1 (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Espl1  extra spindle poles like 1 (S. cerevisiae)   Espl1_predicted  extra spindle poles like 1 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Espl1_predicted  extra spindle poles like 1 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED