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Gene: Dennd2a (DENN domain containing 2A) Rattus norvegicus

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Symbol:

Dennd2a

Name:

DENN domain containing 2A

RGD ID:

1306142

Description:

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be active in actin cytoskeleton. Orthologous to human DENND2A (DENN domain containing 2A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; bisphenol AF.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DENN domain-containing protein 2A; DENN/MADD domain containing 2A; LOC312257; RGD1306142; similar to RIKEN cDNA B930096L08

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DENND2A (DENN domain containing 2A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Dennd2a (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dennd2a (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DENND2A (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DENND2A (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dennd2a (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DENND2A (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DENND2A (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dennd2a (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Dennd2a (DENN domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TERB1 (telomere repeat binding bouquet formation protein 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DENND2A (DENN domain containing 2A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dennd2a (DENN domain containing 2A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-82f1.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dennd2a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	69,199,814 - 69,299,128 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	69,199,814 - 69,298,984 (-)	Ensembl				GRCr8
mRatBN7.2	4	68,233,016 - 68,332,235 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	68,233,958 - 68,332,105 (-)	Ensembl				mRatBN7.2
Rnor_6.0	4	67,242,257 - 67,342,993 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	67,242,271 - 67,301,102 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	67,049,373 - 67,150,087 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	66,965,895 - 67,025,127 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	63,238,288 - 63,337,002 (-)	NCBI		Celera
RGSC_v3.1	4	67,243,131 - 67,357,522 (-)	NCBI
Cytogenetic Map	4	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)

1,1-dichloroethene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (EXP,ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

copper atom (ISO)

copper(0) (ISO)

dexamethasone (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

estriol (ISO)

ethanol (ISO)

fipronil (EXP)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

indometacin (ISO)

Moniliformin (ISO)

ozone (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

progesterone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (EXP)

valdecoxib (EXP)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

retrograde transport, endosome to Golgi (IBA,ISO)

Cellular Component

actin cytoskeleton (IBA,ISO)

cytosol (IEA)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:20937701

Genomics

Comparative Map Data

Dennd2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	69,199,814 - 69,299,128 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	69,199,814 - 69,298,984 (-)	Ensembl				GRCr8
mRatBN7.2	4	68,233,016 - 68,332,235 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	68,233,958 - 68,332,105 (-)	Ensembl				mRatBN7.2
Rnor_6.0	4	67,242,257 - 67,342,993 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	67,242,271 - 67,301,102 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	67,049,373 - 67,150,087 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	66,965,895 - 67,025,127 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	63,238,288 - 63,337,002 (-)	NCBI		Celera
RGSC_v3.1	4	67,243,131 - 67,357,522 (-)	NCBI
Cytogenetic Map	4	q23	NCBI

DENND2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	140,518,419 - 140,641,460 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	140,518,418 - 140,673,993 (-)	Ensembl			hg38	GRCh38
GRCh37	7	140,218,219 - 140,341,260 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	139,864,689 - 139,948,811 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	7	134,940,274 - 135,024,392 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI
HuRef	7	134,513,715 - 134,597,998 (-)	NCBI		HuRef
CHM1_1	7	140,152,470 - 140,236,488 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	141,832,550 - 141,955,637 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	139,556,410 - 139,640,521 (-)	NCBI

Dennd2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	39,439,308 - 39,535,067 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	39,439,312 - 39,534,801 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	39,462,374 - 39,558,145 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	39,462,378 - 39,557,867 (-)	Ensembl			mm10	GRCm38
MGSCv37	6	39,412,377 - 39,507,833 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	39,391,985 - 39,487,441 (-)	NCBI		MGSCv36	mm8
Celera	6	39,447,389 - 39,542,722 (-)	NCBI		Celera
Cytogenetic Map	6	B1	NCBI
cM Map	6	18.26	NCBI

Dennd2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955494	2,781,277 - 2,832,318 (+)	Ensembl
ChiLan1.0	NW_004955494	2,768,097 - 2,831,809 (+)	NCBI	ChiLan1.0	ChiLan1.0

DENND2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	177,310,084 - 177,430,981 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	29,320,338 - 29,441,234 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	132,452,770 - 132,573,674 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	144,926,749 - 145,012,754 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	144,926,749 - 145,012,748 (-)	Ensembl			panPan2	panpan1.1

DENND2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	8,377,389 - 8,479,791 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	8,376,316 - 8,478,890 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	9,220,090 - 9,324,042 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	8,296,862 - 8,400,910 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	8,312,769 - 8,400,907 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	8,247,726 - 8,351,868 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	8,092,452 - 8,196,323 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	8,160,683 - 8,264,684 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dennd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	14,568,065 - 14,635,960 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936592	4,583,735 - 4,647,926 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936592	4,583,826 - 4,647,928 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DENND2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	9,186,903 - 9,310,665 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	18	9,186,537 - 9,310,671 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	9,690,478 - 9,814,084 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DENND2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	109,286,363 - 109,382,696 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666072	5,939,628 - 6,065,679 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dennd2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624765	20,647,522 - 20,696,105 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624765	20,646,129 - 20,700,017 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dennd2a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	100,280,750 - 100,337,196 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dennd2a
314 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	98
Count of miRNA genes:	83
Interacting mature miRNAs:	90
Transcripts:	ENSRNOT00000034549
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	39431983	123203361	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	59753119	104753119	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	41400577	86400577	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	44425024	89425024	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	58817672	103817672	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58080146	80212111	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	40471453	75939996	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	41400603	86400603	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	30448961	82336920	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	65060960	127749483	Rat
2317577	Eae24	Experimental allergic encephalomyelitis QTL 24			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	4	67960112	73752811	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	45429897	149763204	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	51085655	113588029	Rat
2317588	Eae27	Experimental allergic encephalomyelitis QTL 27			nervous system integrity trait (VT:0010566)	percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)	4	69036742	114036742	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	40490442	117737312	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	57613339	151163960	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	57613242	102613242	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	57613242	102613242	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	35113290	80113290	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	57613242	102613242	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	40490442	75726188	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	58079875	82597589	Rat
2306547	Iddm38	Insulin dependent diabetes mellitus QTL 38			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	68353567	113353567	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	59836842	104836842	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	37269577	82269577	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	45429897	149763204	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	61041057	94638356	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63245026	129846354	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	64209744	109209744	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	41400577	86400577	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	57664252	127749483	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58079875	92690793	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63224393	108224393	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	63900458	88813920	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	33538597	116185060	Rat
631671	Iddm11	Insulin dependent diabetes mellitus QTL 11	3.6	0.0012	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	59603319	80216952	Rat

Markers in Region

RH136811

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	68,233,247 - 68,233,374 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	67,242,493 - 67,242,619	NCBI	Rnor6.0
Rnor_5.0	4	67,049,609 - 67,049,735	UniSTS	Rnor5.0
RGSC_v3.4	4	66,966,131 - 66,966,257	UniSTS	RGSC3.4
Celera	4	63,238,524 - 63,238,650	UniSTS
RH 3.4 Map	4	402.32	UniSTS
Cytogenetic Map	4	q22	UniSTS

RH137773

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	4	69,297,256 - 69,297,386 (+)	Marker Load Pipeline
mRatBN7.2	4	68,330,467 - 68,330,597 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	67,341,129 - 67,341,258	NCBI	Rnor6.0
Rnor_5.0	4	67,148,562 - 67,148,691	UniSTS	Rnor5.0
RGSC_v3.4	4	67,062,960 - 67,063,089	UniSTS	RGSC3.4
Celera	4	63,335,229 - 63,335,358	UniSTS
RH 3.4 Map	4	404.15	UniSTS
Cytogenetic Map	4	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	67	59	6	329	167	11	140	79	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC125869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034549 ⟹ ENSRNOP00000034734

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	69,199,814 - 69,298,805 (-)	Ensembl
mRatBN7.2 Ensembl	4	68,233,958 - 68,332,105 (-)	Ensembl
Rnor_6.0 Ensembl	4	67,242,271 - 67,301,102 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097562 ⟹ ENSRNOP00000095232

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	69,199,814 - 69,298,805 (-)	Ensembl
mRatBN7.2 Ensembl	4	68,233,958 - 68,332,105 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110310 ⟹ ENSRNOP00000077830

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	69,199,814 - 69,298,805 (-)	Ensembl
mRatBN7.2 Ensembl	4	68,233,958 - 68,332,105 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000130496 ⟹ ENSRNOP00000109514

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	69,199,814 - 69,298,984 (-)	Ensembl

RefSeq Acc Id:

NM_001427610 ⟹ NP_001414539

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,814 - 69,298,805 (-)	NCBI

RefSeq Acc Id:

XM_006236354 ⟹ XP_006236416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,820 - 69,299,125 (-)	NCBI
mRatBN7.2	4	68,233,016 - 68,332,235 (-)	NCBI
Rnor_6.0	4	67,242,257 - 67,342,993 (-)	NCBI
Rnor_5.0	4	67,049,373 - 67,150,087 (-)	NCBI

Sequence:

show sequence

TTGGTGCTGTCTAAATCTGGTCTTCGGCCCCTGGCTCAGTGCATCTCGAGAATGGACCTCGGCC
GGGGATAGAAGAGAACCCGTGTGGCGATCTTCAGCACAGAAAAGGGTCAAAGCAGAAGTTGCAA
AGCCTAGGGAAGCGTCTAGAAGACAACTGCTTGGGAGGTCCGTTTCTTTGCAAAAGACTAATCC
AGCACCTCCCTTGGGAAGGAGTCCCTCAAGCCCTCACACCCTCATGCTGGAGGCAAGAGTGGAC
ATGCTCAGCTCCAACATGATCATCAGTGGCCCGGCTGCAGACCTCGGTGCTAAAGAAGCCAGCA
GGCCCTTGAAGAAGCAGCTCAGTAGTGTCCAGAACCCTGGACCATCTACCCAAGCCAGAGCCCA
GCCCCTCAGCATAAAGGACAAGATATCCAAGTGGGAAGGCAAGAAGGAGCCACCGGCCTCCGAC
CCTGCCAGGCAAACAGATGGCCAAGAGGACTACCTGCCGTCCTGCAGGGTAGAGAGACGAGGCA
GCGAACTCACCAGAACCAAGAATGGAATGAGGCTTGAAACAGAGAGCTTGCAAAACGACAGCAG
GACAAGAACCATGTGTCAGGACGCAGAACGGTTGCCAGGCCTGAGGCAGATCGATGGTCAGCCA
GAGCCCAGCCAGCCCCGAGGTCGTGAACTGAAGCCCAGTGACCTACGCTTTCAAAGTGACCATC
TCTCCGTGCTGAGACAGGTCAAGAGGCTAGAGAAGGCCTTGAAGGATGGCTCCGCTGGCTTGGA
CCCCCAGTTGCCGGGGACTTGTTATTCACCTCACTGTCTGCCTGACAAGACGGAGGAAGACCAG
CCCATTCCGGAAAGCCACGAAAGTGGGGTCTCCTTAGCATCTGGCCGGAGAGCTCACCACTCGG
AGGTCAGGGAGCCGGGCCCGGAGATCTCAGAGGAGTGGAAAGGCCAGGAGAATGTGTACAGGGG
CTCCAGGTGGCACCCCCAAAAGCCTTTCATCAACCCCGTCCCCAAACCCCGCAGAACATTCAAA
CACGCTGGAGAAGGGGACAAGGACGGAAACCCAGGCATCAGCTTCAAGAAAGAGAAGAGAAACC
TGCCTCCCCTGCCCTCTCTGCCTCCCCCTCCCCCACCGCTGCCTTCCTCCCCTCCTCCCACTTC
TGTGAATAGAAGACTGTGGACTGGGAGGCAGAGACCCAGTGCTGACCACAGAAAGTCCTATGAG
TTCGAGGACTTACTGCAGTCTTCCTCTGAGAACAGCAGGGTGGACTGGTATGCACAGACCAAAT
TGGGACTCACACGCACTTTATCAGAGGAGAACGTCTATGAAGACATTCTAGATCCGCCAATGAA
GGAAAATCCTTATGAGGATGTGGAGTCACATGGCCGCTGCCTGGGCAAGAAGTGTGTCTTGACT
TTCCCTGGATCTCCCACCTCCTCCATCCCGGACACGTCCACCAAGCAGTCCTTGTCCAAGTCTG
CATTTTTCCGGCAAAACTCAGAGAGAAGAAACTTCAAGCTGTTGGACACTAGGAAGCTGAGCCG
GGATGGAACTGGGTCCCCGCTGAGAACTAGCCCTCCCTCCACACCTAGCAGCCCGGACGACACT
TTCTTTAACCTTGGAGACCTACAGAATGGCAGGAAGAAGAAAAAGATCCCCAAGCTGGTGTTGA
GGATCAATGCCATTTATGAGGCCCGGAGAGGAAAGAAACGGGTGAAAAGGCTATCCCAGTCCAC
GGAGAGCAACTCAGGAAAAGTGACAGATGAAAACAGTGAGTCTGACAGCGACACAGAGGAGAAG
CTAAAAGCTCACAGCCAGCGCCTGGTCAATGTGAAGTCACGCCTGAAGCAGGCCCCTCGGTACT
CATCACTTGACCGAGATCTCATTGAGTACCAAGAGAGGCAACTCTTCGAGTACTTTGTGGTCGT
ATCTCTACACAAGAAGCAGGCAGGGGCTGCCTATGTGCCAGAGCTCACCCAGCAATTTCCTCTG
AAGTTAGAAAAGTCATTCAAGTTCCTGAGAGAGGCTGAGGACCAGCTGAAGGCTATTCCCCAGT
TCTGCTTCCCTGATGCCAAGGACTGGAGTCCTGTCCAGGAGTTTACCAGTGAAACGTTCTCGTT
TGTCTTAACTGGAGAAGATGGCAGCAGAAGGTTTGGCTACTGCCGAAGACTGCTGCCTGGAGGC
AAAGGGAAGCGACTTCCTGAGGTTTACTGCATCGTGAGCCGCCTGGGATGCTTCAGCCTCTTTT
CAAAGATCTTGGACGAGGTGGAAAAGAGAAGAGGAATCTCCCCTGCCCTGGTGCAGCCCCTCAT
GAGGAGTGTCATGGAAGCCCCTTTCCCAGCCCTGGGCAAAACCATCACTGTCAAGAACTTCCTA
CCAGGTTCGGGGACTGAGGTGATTGAGCTGTGCCGACCGCTGGACTCCCGGCTAGAGCATGTGG
ACTTTGAGTCTCTGTTCTCCTCCCTCAGTGTCCGACACTTGGTCAGTGTTTTTGCCTCCCTACT
TCTGGAAAGGAGGGTCATCTTCATCGCAGACAAACTCAGCACTCTGTCCAAATGCTGCCACGCC
ATGGTAGCACTCATCTACCCCTTCAGCTGGCAGCACACCTACATCCCAGTGTTGCCGCCTGCCA
TGATTGACATAGTGTGCTCGCCCACGCCCTTCCTCATCGGGCTGCTCTCCAGCTCGCTGCCACT
GCTCAGGGAGCTGCCACTGGAAGAGGTTCTTGTGGTCGATCTCATCAATGATCGATTCCTCAGA
CAGATGGAGGACGAGGATTCCATTCTGCCCCGGAAGCTTCAGGTAGCCCTGGAACACATTCTGG
AGCAGAGGAACGATCTGGCCTGTGACCAGGACGGGGGCCCGCTGGACTGTGTGCATGGGCCCGA
GTCCAGTTCCTTGAGTGAGGTGGTCTCCGAAGCCTTTGTCCGATTTTTTGTGGAGATTGTGGGC
CACTACTCCCTGTTCCTGACGTCGGGCGAGGAGCGGAGCCTGCAGCGAGAGGCCTTCAGAAAAG
CTGTCTCCTCTAAGAGCTTACGACGCTTCCTGGAGGTCTTCATGGAGACCCAGACTTTCCGTGG
CTTCATCCAGGAGCGGGAACTGCGCAGGCAAGATGCCAAAGGTCTGTTTGAAGTCCGAGCCCAG
GAGTACCTAGAAACCTTGCCCAGCGGAGAGCACAGCGGGGTCAATAAATTCCTCAAGGGACTGG
GCAATAAAATGAAGTTTCTCCACAAGAAATAGCCCTCATCTTGGCTCAAGGGAAGACCTCCTCC
CTAGCGCCCCAGTCCTCCCAGGATGGGCCCTGAGCTGGGCAAGTGGCAGACGCTCAGAACAGCT
CTGGGAGAGACCCGCCAGCAGACAGACTGTTGTTACTCTGGTTGGTTGGTTGGTTCTAGGAATC
TTTAAGTCTTAGATATTAAAAGAGAAGAAGAAGGGAAGTGTTTGGCTCTTCATTCAGCTCTCCT
GCCCCACCTCATCTCTTCTGGGCCAGCTTGTTGACAACTGTGGAGCCAGGACATGGGAAGGGTG
GCAGCCGCAGAAGCTATGCCACTGGTTCTTCCCGACTAGTCTATGACGCCACCTGGTGGCAGAG
ACTGTGGACTTTACTGTTCTTGACTTCATTTTTCCCCCCTTAGAAGCCATATAAAACCATTCAT
GCCCAAAAAGTCTGTGACCTTTAGAGGGACACATAAAAACAGGAAATCTTCTCAACTGGTAATA
AAATGTTCTAAGGGTCCTGAAGTTTCTATTTCCTGTGTCCCAACCATGACACTTAGGCCACTGC
TGTGAACCTAGTCCTCTTGGCCAACATAGCTGGGAAAGGCTTCTGTAGTTGCTTCTCTTAATGA
GAGGGAGGACCCAGATCAGCTGACCTGTGGGGCCAGTGAGAATCTGCAAGAGTCCTGTGTGCAG
CAAAAGAAAGGTTCTCAGGCTGGCCTCGGGGCTATCACTCTGAAACTGCTGGGCCCCGGTGACG
GCCACCAGTAATTAACCACATCTGGACTGCCTCTGACCTGGGCAGGATTAATAGGGCTGTGTGG
CTAGGGTCGAGGGAAGCCTGAGAAAGAATGTGAGCATGGGGGCTGAGGAACCCACCACACAAGC
TCCCCGTTTAGGTAACCTTACTGACAGCAATATTCCGTGTATTTTTATATTGCCCCCAGGTGAC
CATGGTTAGTATTTTGGAATATACGTTATTCTTTTCTAACTTATTTTATATTATACTGTTTTAC
TGAAGAACTCCAGGTGAATAAATAAATATATGTTTATCAACATTCCTAGCAAGTATATAATATT
CTATTTTATTAATGTTTTTTGTATTTGACTTAAGCAAAATTTAAAATAAAATTGGGAGAAATGT
GCTGGGCTACTTGTATGAA

hide sequence

RefSeq Acc Id:

XM_008762851 ⟹ XP_008761073

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,820 - 69,298,502 (-)	NCBI
mRatBN7.2	4	68,233,016 - 68,331,717 (-)	NCBI
Rnor_6.0	4	67,242,257 - 67,342,348 (-)	NCBI

Sequence:

show sequence

GCGAGGAGGAAACTGTATTGGCGCGAGCCGGGGATCTTTGCAGGCGGCGCTGGGGACGCTTCCT
CGGAGCCCCGGGGACCGGCGCGGGGAGCGATCCATAGTTCTTCCCCGGATCGGGCTAACTTTAG
GGCCGAAGAAACTTGCAGAATCTGGGCAGAGCCGGGCCCTGCGCTGTGCCGGAGCTCCCGGGCG
CCTGGTCAAAGCAGAAGTTGCAAAGCCTAGGGAAGCGTCTAGAAGACAACTGCTTGGGAGGTCC
GTTTCTTTGCAAAAGACTAATCCAGCACCTCCCTTGGGAAGGAGTCCCTCAAGCCCTCACACCC
TCATGCTGGAGGCAAGAGTGGACATGCTCAGCTCCAACATGATCATCAGTGGCCCGGCTGCAGA
CCTCGGTGCTAAAGAAGCCAGCAGGCCCTTGAAGAAGCAGCTCAGTAGTGTCCAGAACCCTGGA
CCATCTACCCAAGCCAGAGCCCAGCCCCTCAGCATAAAGGACAAGATATCCAAGTGGGAAGGCA
AGAAGGAGCCACCGGCCTCCGACCCTGCCAGGCAAACAGATGGCCAAGAGGACTACCTGCCGTC
CTGCAGGGTAGAGAGACGAGGCAGCGAACTCACCAGAACCAAGAATGGAATGAGGCTTGAAACA
GAGAGCTTGCAAAACGACAGCAGGACAAGAACCATGTGTCAGGACGCAGAACGGTTGCCAGGCC
TGAGGCAGATCGATGGTCAGCCAGAGCCCAGCCAGCCCCGAGGTCGTGAACTGAAGCCCAGTGA
CCTACGCTTTCAAAGTGACCATCTCTCCGTGCTGAGACAGGTCAAGAGGCTAGAGAAGGCCTTG
AAGGATGGCTCCGCTGGCTTGGACCCCCAGTTGCCGGGGACTTGTTATTCACCTCACTGTCTGC
CTGACAAGACGGAGGAAGACCAGCCCATTCCGGAAAGCCACGAAAGTGGGGTCTCCTTAGCATC
TGGCCGGAGAGCTCACCACTCGGAGGTCAGGGAGCCGGGCCCGGAGATCTCAGAGGAGTGGAAA
GGCCAGGAGAATGTGTACAGGGGCTCCAGGTGGCACCCCCAAAAGCCTTTCATCAACCCCGTCC
CCAAACCCCGCAGAACATTCAAACACGCTGGAGAAGGGGACAAGGACGGAAACCCAGGCATCAG
CTTCAAGAAAGAGAAGAGAAACCTGCCTCCCCTGCCCTCTCTGCCTCCCCCTCCCCCACCGCTG
CCTTCCTCCCCTCCTCCCACTTCTGTGAATAGAAGACTGTGGACTGGGAGGCAGAGACCCAGTG
CTGACCACAGAAAGTCCTATGAGTTCGAGGACTTACTGCAGTCTTCCTCTGAGAACAGCAGGGT
GGACTGGTATGCACAGACCAAATTGGGACTCACACGCACTTTATCAGAGGAGAACGTCTATGAA
GACATTCTAGATCCGCCAATGAAGGAAAATCCTTATGAGGATGTGGAGTCACATGGCCGCTGCC
TGGGCAAGAAGTGTGTCTTGACTTTCCCTGGATCTCCCACCTCCTCCATCCCGGACACGTCCAC
CAAGCAGTCCTTGTCCAAGTCTGCATTTTTCCGGCAAAACTCAGAGAGAAGAAACTTCAAGCTG
TTGGACACTAGGAAGCTGAGCCGGGATGGAACTGGGTCCCCGCTGAGAACTAGCCCTCCCTCCA
CACCTAGCAGCCCGGACGACACTTTCTTTAACCTTGGAGACCTACAGAATGGCAGGAAGAAGAA
AAAGATCCCCAAGCTGGTGTTGAGGATCAATGCCATTTATGAGGCCCGGAGAGGAAAGAAACGG
GTGAAAAGGCTATCCCAGTCCACGGAGAGCAACTCAGGAAAAGTGACAGATGAAAACAGTGAGT
CTGACAGCGACACAGAGGAGAAGCTAAAAGCTCACAGCCAGCGCCTGGTCAATGTGAAGTCACG
CCTGAAGCAGGCCCCTCGGTACTCATCACTTGACCGAGATCTCATTGAGTACCAAGAGAGGCAA
CTCTTCGAGTACTTTGTGGTCGTATCTCTACACAAGAAGCAGGCAGGGGCTGCCTATGTGCCAG
AGCTCACCCAGCAATTTCCTCTGAAGTTAGAAAAGTCATTCAAGTTCCTGAGAGAGGCTGAGGA
CCAGCTGAAGGCTATTCCCCAGTTCTGCTTCCCTGATGCCAAGGACTGGAGTCCTGTCCAGGAG
TTTACCAGTGAAACGTTCTCGTTTGTCTTAACTGGAGAAGATGGCAGCAGAAGGTTTGGCTACT
GCCGAAGACTGCTGCCTGGAGGCAAAGGGAAGCGACTTCCTGAGGTTTACTGCATCGTGAGCCG
CCTGGGATGCTTCAGCCTCTTTTCAAAGATCTTGGACGAGGTGGAAAAGAGAAGAGGAATCTCC
CCTGCCCTGGTGCAGCCCCTCATGAGGAGTGTCATGGAAGCCCCTTTCCCAGCCCTGGGCAAAA
CCATCACTGTCAAGAACTTCCTACCAGGTTCGGGGACTGAGGTGATTGAGCTGTGCCGACCGCT
GGACTCCCGGCTAGAGCATGTGGACTTTGAGTCTCTGTTCTCCTCCCTCAGTGTCCGACACTTG
GTCAGTGTTTTTGCCTCCCTACTTCTGGAAAGGAGGGTCATCTTCATCGCAGACAAACTCAGCA
CTCTGTCCAAATGCTGCCACGCCATGGTAGCACTCATCTACCCCTTCAGCTGGCAGCACACCTA
CATCCCAGTGTTGCCGCCTGCCATGATTGACATAGTGTGCTCGCCCACGCCCTTCCTCATCGGG
CTGCTCTCCAGCTCGCTGCCACTGCTCAGGGAGCTGCCACTGGAAGAGGTTCTTGTGGTCGATC
TCATCAATGATCGATTCCTCAGACAGATGGAGGACGAGGATTCCATTCTGCCCCGGAAGCTTCA
GGTAGCCCTGGAACACATTCTGGAGCAGAGGAACGATCTGGCCTGTGACCAGGACGGGGGCCCG
CTGGACTGTGTGCATGGGCCCGAGTCCAGTTCCTTGAGTGAGGTGGTCTCCGAAGCCTTTGTCC
GATTTTTTGTGGAGATTGTGGGCCACTACTCCCTGTTCCTGACGTCGGGCGAGGAGCGGAGCCT
GCAGCGAGAGGCCTTCAGAAAAGCTGTCTCCTCTAAGAGCTTACGACGCTTCCTGGAGGTCTTC
ATGGAGACCCAGACTTTCCGTGGCTTCATCCAGGAGCGGGAACTGCGCAGGCAAGATGCCAAAG
GTCTGTTTGAAGTCCGAGCCCAGGAGTACCTAGAAACCTTGCCCAGCGGAGAGCACAGCGGGGT
CAATAAATTCCTCAAGGGACTGGGCAATAAAATGAAGTTTCTCCACAAGAAATAGCCCTCATCT
TGGCTCAAGGGAAGACCTCCTCCCTAGCGCCCCAGTCCTCCCAGGATGGGCCCTGAGCTGGGCA
AGTGGCAGACGCTCAGAACAGCTCTGGGAGAGACCCGCCAGCAGACAGACTGTTGTTACTCTGG
TTGGTTGGTTGGTTCTAGGAATCTTTAAGTCTTAGATATTAAAAGAGAAGAAGAAGGGAAGTGT
TTGGCTCTTCATTCAGCTCTCCTGCCCCACCTCATCTCTTCTGGGCCAGCTTGTTGACAACTGT
GGAGCCAGGACATGGGAAGGGTGGCAGCCGCAGAAGCTATGCCACTGGTTCTTCCCGACTAGTC
TATGACGCCACCTGGTGGCAGAGACTGTGGACTTTACTGTTCTTGACTTCATTTTTCCCCCCTT
AGAAGCCATATAAAACCATTCATGCCCAAAAAGTCTGTGACCTTTAGAGGGACACATAAAAACA
GGAAATCTTCTCAACTGGTAATAAAATGTTCTAAGGGTCCTGAAGTTTCTATTTCCTGTGTCCC
AACCATGACACTTAGGCCACTGCTGTGAACCTAGTCCTCTTGGCCAACATAGCTGGGAAAGGCT
TCTGTAGTTGCTTCTCTTAATGAGAGGGAGGACCCAGATCAGCTGACCTGTGGGGCCAGTGAGA
ATCTGCAAGAGTCCTGTGTGCAGCAAAAGAAAGGTTCTCAGGCTGGCCTCGGGGCTATCACTCT
GAAACTGCTGGGCCCCGGTGACGGCCACCAGTAATTAACCACATCTGGACTGCCTCTGACCTGG
GCAGGATTAATAGGGCTGTGTGGCTAGGGTCGAGGGAAGCCTGAGAAAGAATGTGAGCATGGGG
GCTGAGGAACCCACCACACAAGCTCCCCGTTTAGGTAACCTTACTGACAGCAATATTCCGTGTA
TTTTTATATTGCCCCCAGGTGACCATGGTTAGTATTTTGGAATATACGTTATTCTTTTCTAACT
TATTTTATATTATACTGTTTTACTGAAGAACTCCAGGTGAATAAATAAATATATGTTTATCAAC
ATTCCTAGCAAGTATATAATATTCTATTTTATTAATGTTTTTTGTATTTGACTTAAGCAAAATT
TAAAATAAAATTGGGAGAAATGTGCTGGGCTACTTGTATGAA

hide sequence

RefSeq Acc Id:

XM_039109021 ⟹ XP_038964949

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,820 - 69,298,857 (-)	NCBI
mRatBN7.2	4	68,233,016 - 68,332,080 (-)	NCBI

RefSeq Acc Id:

XM_039109022 ⟹ XP_038964950

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,820 - 69,298,861 (-)	NCBI
mRatBN7.2	4	68,233,016 - 68,332,085 (-)	NCBI

RefSeq Acc Id:

XM_063286008 ⟹ XP_063142078

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,820 - 69,298,502 (-)	NCBI

RefSeq Acc Id:

XM_063286009 ⟹ XP_063142079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	69,199,820 - 69,299,128 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001414539	(Get FASTA)	NCBI Sequence Viewer
	XP_006236416	(Get FASTA)	NCBI Sequence Viewer
	XP_008761073	(Get FASTA)	NCBI Sequence Viewer
	XP_038964949	(Get FASTA)	NCBI Sequence Viewer
	XP_038964950	(Get FASTA)	NCBI Sequence Viewer
	XP_063142078	(Get FASTA)	NCBI Sequence Viewer
	XP_063142079	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM15389	(Get FASTA)	NCBI Sequence Viewer
	EDM15390	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034734
	ENSRNOP00000034734.3
	ENSRNOP00000077830.1
	ENSRNOP00000095232.1
	ENSRNOP00000109514.1

RefSeq Acc Id:	XP_006236416 ⟸ XM_006236354
- Peptide Label:	isoform X1
- UniProtKB:	D3ZLQ1 (UniProtKB/TrEMBL), A0A8I6AL22 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLEARVDMLSSNMIISGPAADLGAKEASRPLKKQLSSVQNPGPSTQARAQPLSIKDKISKWEGK KEPPASDPARQTDGQEDYLPSCRVERRGSELTRTKNGMRLETESLQNDSRTRTMCQDAERLPGL RQIDGQPEPSQPRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQLPGTCYSPHCLP DKTEEDQPIPESHESGVSLASGRRAHHSEVREPGPEISEEWKGQENVYRGSRWHPQKPFINPVP KPRRTFKHAGEGDKDGNPGISFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSA DHRKSYEFEDLLQSSSENSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDVESHGRCL GKKCVLTFPGSPTSSIPDTSTKQSLSKSAFFRQNSERRNFKLLDTRKLSRDGTGSPLRTSPPST PSSPDDTFFNLGDLQNGRKKKKIPKLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDENSES DSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPE LTQQFPLKLEKSFKFLREAEDQLKAIPQFCFPDAKDWSPVQEFTSETFSFVLTGEDGSRRFGYC RRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGKT ITVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLST LSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDL INDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVR FFVEIVGHYSLFLTSGEERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKG LFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK hide sequence

RefSeq Acc Id:	XP_008761073 ⟸ XM_008762851
- Peptide Label:	isoform X1
- UniProtKB:	D3ZLQ1 (UniProtKB/TrEMBL), A0A8I6AL22 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLEARVDMLSSNMIISGPAADLGAKEASRPLKKQLSSVQNPGPSTQARAQPLSIKDKISKWEGK KEPPASDPARQTDGQEDYLPSCRVERRGSELTRTKNGMRLETESLQNDSRTRTMCQDAERLPGL RQIDGQPEPSQPRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQLPGTCYSPHCLP DKTEEDQPIPESHESGVSLASGRRAHHSEVREPGPEISEEWKGQENVYRGSRWHPQKPFINPVP KPRRTFKHAGEGDKDGNPGISFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSA DHRKSYEFEDLLQSSSENSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDVESHGRCL GKKCVLTFPGSPTSSIPDTSTKQSLSKSAFFRQNSERRNFKLLDTRKLSRDGTGSPLRTSPPST PSSPDDTFFNLGDLQNGRKKKKIPKLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDENSES DSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPE LTQQFPLKLEKSFKFLREAEDQLKAIPQFCFPDAKDWSPVQEFTSETFSFVLTGEDGSRRFGYC RRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGKT ITVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLST LSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDL INDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVR FFVEIVGHYSLFLTSGEERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKG LFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK hide sequence

Ensembl Acc Id:

ENSRNOP00000034734 ⟸ ENSRNOT00000034549

RefSeq Acc Id:	XP_038964950 ⟸ XM_039109022
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AL22 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038964949 ⟸ XM_039109021
- Peptide Label:	isoform X1
- UniProtKB:	D3ZLQ1 (UniProtKB/TrEMBL), A0A8I6AL22 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095232 ⟸ ENSRNOT00000097562

Ensembl Acc Id:

ENSRNOP00000077830 ⟸ ENSRNOT00000110310

RefSeq Acc Id:	NP_001414539 ⟸ NM_001427610
- UniProtKB:	D3ZLQ1 (UniProtKB/TrEMBL), A0A8I6AL22 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142079 ⟸ XM_063286009
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AL22 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142078 ⟸ XM_063286008
- Peptide Label:	isoform X1
- UniProtKB:	D3ZLQ1 (UniProtKB/TrEMBL), A0A8I6AL22 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000109514 ⟸ ENSRNOT00000130496

Protein Domains

uDENN

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZLQ1-F1-model_v2	AlphaFold	D3ZLQ1	1-998	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306142	AgrOrtholog
BioCyc Gene	G2FUF-45186	BioCyc
Ensembl Genes	ENSRNOG00000026748	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034549	ENTREZGENE
	ENSRNOT00000034549.7	UniProtKB/TrEMBL
	ENSRNOT00000097562.2	UniProtKB/TrEMBL
	ENSRNOT00000110310.2	UniProtKB/TrEMBL
	ENSRNOT00000130496.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.450.200	UniProtKB/TrEMBL
	3.40.50.11500	UniProtKB/TrEMBL
InterPro	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	DENN_C	UniProtKB/TrEMBL
	DENN_domain_containing_2	UniProtKB/TrEMBL
	Tripartite_DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
KEGG Report	rno:312257	UniProtKB/TrEMBL
NCBI Gene	312257	ENTREZGENE
PANTHER	DENN DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	DENN DOMAIN-CONTAINING PROTEIN 2A	UniProtKB/TrEMBL
Pfam	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
PhenoGen	Dennd2a	PhenoGen
PROSITE	DENN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000026748	RatGTEx
SMART	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
UniProt	A0A8I5YCI8_RAT	UniProtKB/TrEMBL
	A0A8I6AL22	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LYI0_RAT	UniProtKB/TrEMBL
	D3ZLQ1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Dennd2a	DENN domain containing 2A	Dennd2a	DENN/MADD domain containing 2A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Dennd2a	DENN/MADD domain containing 2A	RGD1306142_predicted	similar to RIKEN cDNA B930096L08 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1306142_predicted	similar to RIKEN cDNA B930096L08 (predicted)	LOC312257_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC312257_predicted	similar to RIKEN cDNA B930096L08 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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