Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Daam2 | Rat | osteoporosis | | ISO | DAAM2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:30598549 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Daam2 | Rat | osteoporosis | | ISO | DAAM2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:30598549 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| PMID:18570454 | PMID:22227309 | PMID:24091014 | PMID:25754822 | PMID:36681175 |
| Daam2 (Rattus norvegicus - Norway rat) |
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| DAAM2 (Homo sapiens - human) |
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| Daam2 (Mus musculus - house mouse) |
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| Daam2 (Chinchilla lanigera - long-tailed chinchilla) |
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| DAAM2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DAAM2 (Canis lupus familiaris - dog) |
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| Daam2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DAAM2 (Sus scrofa - pig) |
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| DAAM2 (Chlorocebus sabaeus - green monkey) |
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| Daam2 (Heterocephalus glaber - naked mole-rat) |
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| Daam2 (Rattus rattus - black rat) |
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Variants in Daam2
856 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| ha1547 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 161 | 91 | 90 | 59 | 61 | 59 | 6 | 325 | 161 | 11 | 140 | 81 | 92 | 31 | 16 | 16 |
| RefSeq Transcripts | NM_001427649 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_008766918 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017603759 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084447 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084448 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084449 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084450 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084451 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084452 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039084455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063267081 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063267082 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_010054590 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | JAXUCZ010000009 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000085782 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000088651 ⟹ ENSRNOP00000074902 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000103217 ⟹ ENSRNOP00000094568 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000117349 ⟹ ENSRNOP00000087375 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001427649 ⟹ NP_001414578 | ||||||||
| RefSeq Status: | VALIDATED | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084447 ⟹ XP_038940375 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084448 ⟹ XP_038940376 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084449 ⟹ XP_038940377 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084450 ⟹ XP_038940378 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084451 ⟹ XP_038940379 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084452 ⟹ XP_038940380 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039084455 ⟹ XP_038940383 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063267081 ⟹ XP_063123151 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063267082 ⟹ XP_063123152 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XR_010054590 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001414578 | (Get FASTA) | NCBI Sequence Viewer |
| XP_038940375 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038940376 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038940377 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038940378 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038940379 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038940380 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038940383 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063123151 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063123152 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000074902 | ||
| ENSRNOP00000074902.2 | |||
| ENSRNOP00000094568 | |||
| ENSRNOP00000094568.1 |
| Ensembl Acc Id: | ENSRNOP00000074902 ⟸ ENSRNOT00000088651 |
| RefSeq Acc Id: | XP_038940375 ⟸ XM_039084447 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038940380 ⟸ XM_039084452 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038940383 ⟸ XM_039084455 |
| - Peptide Label: | isoform X5 |
| RefSeq Acc Id: | XP_038940378 ⟸ XM_039084450 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038940377 ⟸ XM_039084449 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038940379 ⟸ XM_039084451 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038940376 ⟸ XM_039084448 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| Ensembl Acc Id: | ENSRNOP00000087375 ⟸ ENSRNOT00000117349 |
| Ensembl Acc Id: | ENSRNOP00000094568 ⟸ ENSRNOT00000103217 |
| RefSeq Acc Id: | XP_063123151 ⟸ XM_063267081 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | NP_001414578 ⟸ NM_001427649 |
| - UniProtKB: | A0A8I6B158 (UniProtKB/TrEMBL), A0A0G2K988 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063123152 ⟸ XM_063267082 |
| - Peptide Label: | isoform X4 |
| - UniProtKB: | A0A8I6B158 (UniProtKB/TrEMBL), A0A0G2K988 (UniProtKB/TrEMBL) |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-A0A0G2K988-F1-model_v2 | AlphaFold | A0A0G2K988 | 1-1117 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1306128 | AgrOrtholog |
| BioCyc Gene | G2FUF-28342 | BioCyc |
| Ensembl Genes | ENSRNOG00000052783 | Ensembl |
| ENSRNOG00000053945 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000088651 | ENTREZGENE |
| ENSRNOT00000088651.3 | UniProtKB/TrEMBL | |
| ENSRNOT00000103217 | ENTREZGENE | |
| ENSRNOT00000103217.2 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.20.58.2220 | UniProtKB/TrEMBL |
| 1.25.10.10 | UniProtKB/TrEMBL | |
| Formin, FH3 diaphanous domain | UniProtKB/TrEMBL | |
| InterPro | ARM-like | UniProtKB/TrEMBL |
| ARM-type_fold | UniProtKB/TrEMBL | |
| DAD_dom | UniProtKB/TrEMBL | |
| FH2_Formin | UniProtKB/TrEMBL | |
| FH2_Formin_sf | UniProtKB/TrEMBL | |
| FH3_dom | UniProtKB/TrEMBL | |
| Formin_Homology | UniProtKB/TrEMBL | |
| GBD/FH3_dom | UniProtKB/TrEMBL | |
| GTPase-bd | UniProtKB/TrEMBL | |
| NCBI Gene | 316201 | ENTREZGENE |
| PANTHER | DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 | UniProtKB/TrEMBL |
| FORMIN HOMOLOGY 2 FAMILY MEMBER | UniProtKB/TrEMBL | |
| Pfam | Drf_FH3 | UniProtKB/TrEMBL |
| Drf_GBD | UniProtKB/TrEMBL | |
| FH2 | UniProtKB/TrEMBL | |
| PhenoGen | Daam2 | PhenoGen |
| PROSITE | DAD | UniProtKB/TrEMBL |
| FH2 | UniProtKB/TrEMBL | |
| GBD_FH3 | UniProtKB/TrEMBL | |
| RatGTEx | ENSRNOG00000052783 | RatGTEx |
| ENSRNOG00000053945 | RatGTEx | |
| SMART | Drf_FH3 | UniProtKB/TrEMBL |
| Drf_GBD | UniProtKB/TrEMBL | |
| FH2 | UniProtKB/TrEMBL | |
| Superfamily-SCOP | Formin homology 2 domain (FH2 domain) | UniProtKB/TrEMBL |
| SSF48371 | UniProtKB/TrEMBL | |
| UniProt | A0A0G2K988 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A8I6B158 | ENTREZGENE, UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2021-03-09 | Daam2 | dishevelled associated activator of morphogenesis 2 | LOC102547039 | disheveled-associated activator of morphogenesis 2-like | Data merged from RGD:7643518 | 737654 | PROVISIONAL |
| 2013-12-18 | LOC102547039 | disheveled-associated activator of morphogenesis 2-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2008-04-30 | Daam2 | dishevelled associated activator of morphogenesis 2 | Daam2_predicted | dishevelled associated activator of morphogenesis 2 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Daam2_predicted | dishevelled associated activator of morphogenesis 2 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |