Hace1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1) - Rat Genome Database

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Gene: Hace1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1) Rattus norvegicus
Analyze
Symbol: Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
RGD ID: 1306114
Description: Predicted to enable small GTPase binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including Golgi organization; protein K48-linked ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in Golgi cisterna membrane; endoplasmic reticulum; and nuclear body. Predicted to be active in Golgi membrane and nucleus. Orthologous to human HACE1 (HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1); INTERACTS WITH 1,3-dinitrobenzene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase HACE1; HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1; HECT-type E3 ubiquitin transferase HACE1; LOC361866
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82050,618,004 - 50,733,460 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2050,618,004 - 50,733,466 (+)EnsemblGRCr8
mRatBN7.22049,035,312 - 49,151,103 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2049,035,648 - 49,151,103 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2050,772,071 - 50,880,272 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02050,421,828 - 50,529,931 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02051,106,137 - 51,214,330 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02050,652,489 - 50,783,937 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2050,652,745 - 50,783,937 (+)Ensemblrn6Rnor6.0
Rnor_5.02052,261,033 - 52,394,868 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42049,856,040 - 49,973,091 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2050,882,914 - 50,991,947 (-)NCBICelera
RGSC_v3.12049,865,875 - 50,001,077 (+)NCBI
Cytogenetic Map20q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
endoplasmic reticulum  (IEA,ISO)
Golgi cisterna membrane  (IEA)
Golgi membrane  (IBA,IEA,ISO,ISS)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:15254018   PMID:21988917   PMID:22036506  


Genomics

Comparative Map Data
Hace1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82050,618,004 - 50,733,460 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2050,618,004 - 50,733,466 (+)EnsemblGRCr8
mRatBN7.22049,035,312 - 49,151,103 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2049,035,648 - 49,151,103 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2050,772,071 - 50,880,272 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02050,421,828 - 50,529,931 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02051,106,137 - 51,214,330 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02050,652,489 - 50,783,937 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2050,652,745 - 50,783,937 (+)Ensemblrn6Rnor6.0
Rnor_5.02052,261,033 - 52,394,868 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42049,856,040 - 49,973,091 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2050,882,914 - 50,991,947 (-)NCBICelera
RGSC_v3.12049,865,875 - 50,001,077 (+)NCBI
Cytogenetic Map20q13NCBI
HACE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386104,728,094 - 104,859,919 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6104,728,094 - 104,859,919 (-)Ensemblhg38GRCh38
GRCh376105,175,969 - 105,307,794 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366105,282,661 - 105,414,487 (-)NCBIBuild 36Build 36hg18NCBI36
Celera6105,798,434 - 105,930,284 (-)NCBICelera
Cytogenetic Map6q16.3NCBI
HuRef6102,619,748 - 102,751,184 (-)NCBIHuRef
CHM1_16105,437,913 - 105,569,648 (-)NCBICHM1_1
T2T-CHM13v2.06105,904,367 - 106,035,941 (-)NCBIT2T-CHM13v2.0
Hace1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391045,453,911 - 45,588,441 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1045,453,925 - 45,588,441 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381045,577,814 - 45,712,345 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1045,577,829 - 45,712,345 (+)Ensemblmm10GRCm38
MGSCv371045,297,635 - 45,432,151 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361045,266,304 - 45,400,659 (+)NCBIMGSCv36mm8
Celera1046,446,600 - 46,579,346 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.65NCBI
Hace1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541130,178,297 - 30,261,009 (-)Ensembl
ChiLan1.0NW_00495541130,178,297 - 30,260,627 (-)NCBIChiLan1.0ChiLan1.0
HACE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25124,747,626 - 124,880,278 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16122,634,129 - 122,766,751 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06102,541,992 - 102,674,281 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16106,419,867 - 106,551,004 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6106,419,867 - 106,551,007 (-)EnsemblpanPan2panpan1.1
HACE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11262,231,642 - 62,337,242 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1262,227,078 - 62,337,183 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1262,019,271 - 62,126,625 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01263,079,955 - 63,187,531 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1263,080,915 - 63,187,586 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11262,436,034 - 62,543,942 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01262,277,683 - 62,385,051 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01262,555,861 - 62,663,750 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hace1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494697,225,086 - 97,307,884 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365641,499,634 - 1,582,759 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365641,499,918 - 1,582,719 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HACE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl170,993,342 - 71,105,012 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1170,994,033 - 71,104,998 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2180,233,231 - 80,376,193 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HACE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11368,932,866 - 69,059,126 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1368,932,824 - 69,061,053 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604041,280,266 - 41,406,167 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hace1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13219,412,485 - 219,520,312 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hace1
986 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:69
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000000365
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202668936256021148Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202679235356021148Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202668936256021148Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)202074558556021148Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202668936256021148Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202668936256021148Rat

Markers in Region
RH144004  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22049,123,610 - 49,123,784 (+)MAPPERmRatBN7.2
Rnor_6.02050,756,705 - 50,756,878NCBIRnor6.0
Rnor_5.02052,367,636 - 52,367,809UniSTSRnor5.0
RGSC_v3.42049,945,589 - 49,945,762UniSTSRGSC3.4
Celera2050,910,191 - 50,910,364UniSTS
RH 3.4 Map20506.9UniSTS
Cytogenetic Map20q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 355 192 11 144 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BP504022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA505899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB327407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB609910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO402715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000365   ⟹   ENSRNOP00000000365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,004 - 50,733,454 (+)Ensembl
mRatBN7.2 Ensembl2049,035,648 - 49,151,103 (+)Ensembl
Rnor_6.0 Ensembl2050,652,745 - 50,783,937 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106005   ⟹   ENSRNOP00000085147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,045 - 50,733,454 (+)Ensembl
mRatBN7.2 Ensembl2049,035,648 - 49,151,103 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111799   ⟹   ENSRNOP00000090381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,004 - 50,733,454 (+)Ensembl
mRatBN7.2 Ensembl2049,035,648 - 49,151,103 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130620   ⟹   ENSRNOP00000110872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,081 - 50,733,357 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139890   ⟹   ENSRNOP00000104608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,017 - 50,733,466 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000141456   ⟹   ENSRNOP00000107784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,046 - 50,733,357 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146450   ⟹   ENSRNOP00000101439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2050,618,007 - 50,733,351 (+)Ensembl
RefSeq Acc Id: NM_001108539   ⟹   NP_001102009
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,254 - 50,733,460 (+)NCBI
mRatBN7.22049,035,899 - 49,151,103 (+)NCBI
Rnor_6.02050,652,745 - 50,783,937 (+)NCBI
Rnor_5.02052,261,033 - 52,394,868 (+)NCBI
RGSC_v3.42049,856,040 - 49,973,091 (+)RGD
Celera2050,882,914 - 50,991,947 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256595   ⟹   XP_006256657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
Rnor_6.02050,652,489 - 50,783,932 (+)NCBI
Rnor_5.02052,261,033 - 52,394,868 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256597   ⟹   XP_006256659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
Rnor_6.02050,652,489 - 50,783,932 (+)NCBI
Rnor_5.02052,261,033 - 52,394,868 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098889   ⟹   XP_038954817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098890   ⟹   XP_038954818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098891   ⟹   XP_038954819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098892   ⟹   XP_038954820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098894   ⟹   XP_038954822
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098895   ⟹   XP_038954823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
mRatBN7.22049,035,312 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098896   ⟹   XP_038954824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,625,260 - 50,733,455 (+)NCBI
mRatBN7.22049,035,932 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098897   ⟹   XP_038954825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,627,206 - 50,733,455 (+)NCBI
mRatBN7.22049,044,848 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098898   ⟹   XP_038954826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,627,206 - 50,733,455 (+)NCBI
mRatBN7.22049,044,848 - 49,151,098 (+)NCBI
RefSeq Acc Id: XM_039098899   ⟹   XP_038954827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,700,790 (+)NCBI
mRatBN7.22049,035,312 - 49,118,462 (+)NCBI
RefSeq Acc Id: XM_063279320   ⟹   XP_063135390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
RefSeq Acc Id: XM_063279321   ⟹   XP_063135391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
RefSeq Acc Id: XM_063279322   ⟹   XP_063135392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,618,004 - 50,733,455 (+)NCBI
RefSeq Acc Id: XM_063279324   ⟹   XP_063135394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82050,625,260 - 50,733,455 (+)NCBI
RefSeq Acc Id: NP_001102009   ⟸   NM_001108539
- UniProtKB: D3ZBM8 (UniProtKB/Swiss-Prot),   D3ZBM7 (UniProtKB/Swiss-Prot),   A0A8I6ADJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256657   ⟸   XM_006256595
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ADJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256659   ⟸   XM_006256597
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ADJ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000365   ⟸   ENSRNOT00000000365
RefSeq Acc Id: XP_038954817   ⟸   XM_039098889
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ADJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954820   ⟸   XM_039098892
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954822   ⟸   XM_039098894
- Peptide Label: isoform X9
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954819   ⟸   XM_039098891
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954823   ⟸   XM_039098895
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954818   ⟸   XM_039098890
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954827   ⟸   XM_039098899
- Peptide Label: isoform X15
- UniProtKB: A6K6U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954824   ⟸   XM_039098896
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954825   ⟸   XM_039098897
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954826   ⟸   XM_039098898
- Peptide Label: isoform X14
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085147   ⟸   ENSRNOT00000106005
Ensembl Acc Id: ENSRNOP00000090381   ⟸   ENSRNOT00000111799
RefSeq Acc Id: XP_063135390   ⟸   XM_063279320
- Peptide Label: isoform X3
- UniProtKB: A0A8I6ADJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135391   ⟸   XM_063279321
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135392   ⟸   XM_063279322
- Peptide Label: isoform X10
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135394   ⟸   XM_063279324
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A1L8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101439   ⟸   ENSRNOT00000146450
Ensembl Acc Id: ENSRNOP00000107784   ⟸   ENSRNOT00000141456
Ensembl Acc Id: ENSRNOP00000110872   ⟸   ENSRNOT00000130620
Ensembl Acc Id: ENSRNOP00000104608   ⟸   ENSRNOT00000139890
Protein Domains
HECT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBM7-F1-model_v2 AlphaFold D3ZBM7 1-909 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306114 AgrOrtholog
BioCyc Gene G2FUF-3260 BioCyc
Ensembl Genes ENSRNOG00000000327 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000365 ENTREZGENE
  ENSRNOT00000000365.5 UniProtKB/Swiss-Prot
  ENSRNOT00000106005 ENTREZGENE
  ENSRNOT00000111799 ENTREZGENE
  ENSRNOT00000130620 ENTREZGENE
  ENSRNOT00000139890 ENTREZGENE
  ENSRNOT00000141456 ENTREZGENE
  ENSRNOT00000146450 ENTREZGENE
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot
  Hect, E3 ligase catalytic domain UniProtKB/Swiss-Prot
  Hect, E3 ligase catalytic domain UniProtKB/Swiss-Prot
  Hect, E3 ligase catalytic domains UniProtKB/Swiss-Prot
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  E3_ubiq-protein_ligase UniProtKB/Swiss-Prot
  HECT_dom UniProtKB/Swiss-Prot
  Hect_E3_ubiquitin_ligase UniProtKB/Swiss-Prot
KEGG Report rno:361866 UniProtKB/Swiss-Prot
NCBI Gene 361866 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE HACE1 UniProtKB/Swiss-Prot
  HECT DOMAIN UBIQUITIN-PROTEIN LIGASE UniProtKB/Swiss-Prot
Pfam Ank_2 UniProtKB/Swiss-Prot
  Ank_5 UniProtKB/Swiss-Prot
  HECT UniProtKB/Swiss-Prot
PhenoGen Hace1 PhenoGen
PRINTS ANKYRIN UniProtKB/Swiss-Prot
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
  HECT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000000327 RatGTEx
SMART ANK UniProtKB/Swiss-Prot
  HECTc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot
  SSF56204 UniProtKB/Swiss-Prot
UniProt A0A8I6A1L8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LAJ6_RAT UniProtKB/TrEMBL
  A0ABK0LRR3_RAT UniProtKB/TrEMBL
  A0ABK0M0E2_RAT UniProtKB/TrEMBL
  A0ABK0M5W5_RAT UniProtKB/TrEMBL
  A6K6U6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBM7 ENTREZGENE
  D3ZBM8 ENTREZGENE
  HACE1_RAT UniProtKB/Swiss-Prot
UniProt Secondary D3ZBM8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Hace1  HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1   Hace1_predicted  HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Hace1_predicted  HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED