Helz2 (helicase with zinc finger 2) - Rat Genome Database

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Gene: Helz2 (helicase with zinc finger 2) Rattus norvegicus
Analyze
Symbol: Helz2
Name: helicase with zinc finger 2
RGD ID: 1306056
Description: Predicted to enable exoribonuclease II activity; helicase activity; and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Orthologous to human HELZ2 (helicase with zinc finger 2); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3'-5' exoribonuclease HELZ2; helicase with zinc finger 2, transcriptional coactivator; helicase with zinc finger domain 2; LOC296474; peroxisomal proliferator-activated receptor A interacting complex 285; peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein; Pric285; RGD1306056; similar to Peroxisomal proliferator-activated receptor A interacting complex 285 kDa protein (PPAR-alpha interacting complex protein 285)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Helz2em3Mcwi ; Helz2em4Mcwi
Genetic Models: FHH-Chr 3BN-Helz2em4Mcwi ; FHH-Chr 3BN-Helz2em3Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,716,370 - 188,730,776 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3188,716,370 - 188,730,716 (-)EnsemblGRCr8
mRatBN7.23168,338,813 - 168,353,219 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,338,813 - 168,353,159 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3172,719,445 - 172,733,793 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,678,548 - 181,692,896 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,339,765 - 178,354,111 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,730,024 - 176,744,382 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,731,769 - 176,744,377 (-)Ensemblrn6Rnor6.0
Rnor_5.03180,439,958 - 180,454,321 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,368,815 - 170,382,086 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3164,232,819 - 164,247,178 (+)NCBICelera
RGSC_v3.13170,275,925 - 170,286,359 (-)NCBI
Cytogenetic Map3q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
coumestrol  (ISO)
cyproterone acetate  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
fenthion  (ISO)
finasteride  (EXP)
flutamide  (EXP)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
temozolomide  (ISO)
testosterone  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
nucleoplasm  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12189208   PMID:12477932   PMID:16239304   PMID:19946888   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Helz2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,716,370 - 188,730,776 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3188,716,370 - 188,730,716 (-)EnsemblGRCr8
mRatBN7.23168,338,813 - 168,353,219 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,338,813 - 168,353,159 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3172,719,445 - 172,733,793 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,678,548 - 181,692,896 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,339,765 - 178,354,111 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,730,024 - 176,744,382 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,731,769 - 176,744,377 (-)Ensemblrn6Rnor6.0
Rnor_5.03180,439,958 - 180,454,321 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,368,815 - 170,382,086 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3164,232,819 - 164,247,178 (+)NCBICelera
RGSC_v3.13170,275,925 - 170,286,359 (-)NCBI
Cytogenetic Map3q43NCBI
HELZ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382063,558,086 - 63,574,239 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2063,558,086 - 63,574,239 (-)Ensemblhg38GRCh38
GRCh372062,189,439 - 62,205,592 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362061,659,883 - 61,676,036 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2058,869,799 - 58,886,258 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2058,919,675 - 58,936,082 (-)NCBIHuRef
CHM1_12062,090,447 - 62,106,588 (-)NCBICHM1_1
T2T-CHM13v2.02065,370,683 - 65,387,688 (-)NCBIT2T-CHM13v2.0
Helz2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,869,408 - 180,883,851 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,869,408 - 180,883,820 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382181,227,615 - 181,242,058 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,227,615 - 181,242,027 (-)Ensemblmm10GRCm38
MGSCv372180,962,320 - 180,976,732 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362181,157,014 - 181,171,434 (-)NCBIMGSCv36mm8
Celera2185,310,414 - 185,324,847 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.63NCBI
Helz2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528652,543 - 668,744 (+)Ensembl
ChiLan1.0NW_004955528652,381 - 666,923 (+)NCBIChiLan1.0ChiLan1.0
HELZ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,362,005 - 69,377,640 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,354,017 - 69,368,554 (-)NCBINHGRI_mPanPan1
PanPan1.12061,483,623 - 61,498,995 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,483,623 - 61,498,083 (-)EnsemblpanPan2panpan1.1
HELZ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12447,147,346 - 47,161,452 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2447,148,444 - 47,161,570 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2446,346,103 - 46,361,195 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02448,117,040 - 48,129,433 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UNSW_CanFamBas_1.02447,256,613 - 47,271,807 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,994,606 - 48,009,739 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Helz2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,397,491 - 195,411,463 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,852,109 - 10,863,969 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,851,149 - 10,863,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HELZ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,919,847 - 59,932,546 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1659,916,378 - 59,932,537 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,879,169 - 54,894,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HELZ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12632,572 - 647,618 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2633,042 - 647,613 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605048,191,009 - 48,206,523 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Helz2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,212,634 - 29,228,731 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474129,213,954 - 29,228,567 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Helz2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15158,324,633 - 158,339,224 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:193
Count of miRNA genes:133
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000017787
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3181611379189428310Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat

Markers in Region
BC006779  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,346,199 - 168,347,362 (+)MAPPERmRatBN7.2
Rnor_6.03176,737,411 - 176,738,573NCBIRnor6.0
Rnor_5.03180,447,345 - 180,448,507UniSTSRnor5.0
Celera3164,238,629 - 164,239,791UniSTS
Cytogenetic Map3q43UniSTS


Genetic Models
This gene Helz2 is modified in the following models/strains:
FHH-Chr 3BN-Helz2em4Mcwi     FHH-Chr 3BN-Helz2em3Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017787   ⟹   ENSRNOP00000017787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,716,487 - 188,730,716 (-)Ensembl
mRatBN7.2 Ensembl3168,338,930 - 168,353,159 (-)Ensembl
Rnor_6.0 Ensembl3176,731,769 - 176,744,377 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113133   ⟹   ENSRNOP00000080222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,716,370 - 188,730,716 (-)Ensembl
mRatBN7.2 Ensembl3168,338,813 - 168,353,159 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118980   ⟹   ENSRNOP00000085706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,718,314 - 188,730,716 (-)Ensembl
mRatBN7.2 Ensembl3168,339,289 - 168,353,159 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119552   ⟹   ENSRNOP00000091979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,716,370 - 188,730,716 (-)Ensembl
mRatBN7.2 Ensembl3168,338,813 - 168,353,159 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137502   ⟹   ENSRNOP00000101102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,718,277 - 188,730,716 (-)Ensembl
RefSeq Acc Id: NM_001305276   ⟹   NP_001292205
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,716,370 - 188,730,716 (-)NCBI
mRatBN7.23168,338,813 - 168,353,159 (-)NCBI
Rnor_6.03176,730,024 - 176,744,370 (-)NCBI
Celera3164,232,819 - 164,247,178 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104695   ⟹   XP_038960623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,716,370 - 188,730,240 (-)NCBI
mRatBN7.23168,338,813 - 168,352,675 (-)NCBI
RefSeq Acc Id: XM_063283443   ⟹   XP_063139513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,718,429 - 188,730,776 (-)NCBI
RefSeq Acc Id: XM_063283444   ⟹   XP_063139514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,718,429 - 188,730,776 (-)NCBI
RefSeq Acc Id: XM_063283445   ⟹   XP_063139515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,718,838 - 188,730,776 (-)NCBI
RefSeq Acc Id: NP_001292205   ⟸   NM_001305276
- UniProtKB: A0A8I5ZPT9 (UniProtKB/TrEMBL),   A0A8I6AGQ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017787   ⟸   ENSRNOT00000017787
RefSeq Acc Id: XP_038960623   ⟸   XM_039104695
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZPT9 (UniProtKB/TrEMBL),   A0A8I6AGQ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091979   ⟸   ENSRNOT00000119552
Ensembl Acc Id: ENSRNOP00000085706   ⟸   ENSRNOT00000118980
Ensembl Acc Id: ENSRNOP00000080222   ⟸   ENSRNOT00000113133
RefSeq Acc Id: XP_063139514   ⟸   XM_063283444
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GD78 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139513   ⟸   XM_063283443
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GD78 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139515   ⟸   XM_063283445
- Peptide Label: isoform X4
- UniProtKB: A0A8I6GD78 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101102   ⟸   ENSRNOT00000137502
Protein Domains
AAA+ ATPase   RNB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADC2-F1-model_v2 AlphaFold D4ADC2 1-2683 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692758
Promoter ID:EPDNEW_R3274
Type:initiation region
Name:Helz2_1
Description:helicase with zinc finger 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03176,744,337 - 176,744,397EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306056 AgrOrtholog
BioCyc Gene G2FUF-46297 BioCyc
Ensembl Genes ENSRNOG00000013267 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017787.7 UniProtKB/TrEMBL
  ENSRNOT00000113133 ENTREZGENE
  ENSRNOT00000113133.2 UniProtKB/TrEMBL
  ENSRNOT00000118980 ENTREZGENE
  ENSRNOT00000118980.2 UniProtKB/TrEMBL
  ENSRNOT00000119552.2 UniProtKB/TrEMBL
  ENSRNOT00000137502 ENTREZGENE
  ENSRNOT00000137502.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  Coronavir_polyprotein_1ab UniProtKB/TrEMBL
  DNA2/NAM7_AAA_11 UniProtKB/TrEMBL
  DNA2/NAM7_like_AAA_12 UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  OB_HELZ2 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNase_II/R UniProtKB/TrEMBL
  SF1_C_Upf1 UniProtKB/TrEMBL
KEGG Report rno:296474 UniProtKB/TrEMBL
NCBI Gene 296474 ENTREZGENE
PANTHER DNA-BINDING PROTEIN SMUBP-2 UniProtKB/TrEMBL
  DNA2/NAM7 HELICASE FAMILY MEMBER UniProtKB/TrEMBL
  HELICASE WITH ZINC FINGER 2 UniProtKB/TrEMBL
Pfam AAA_11 UniProtKB/TrEMBL
  AAA_12 UniProtKB/TrEMBL
  OB_HELZ2 UniProtKB/TrEMBL
  RNB UniProtKB/TrEMBL
PhenoGen Helz2 PhenoGen
RatGTEx ENSRNOG00000013267 RatGTEx
SMART AAA UniProtKB/TrEMBL
  RNB UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5ZPT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AGQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GD78 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LLG9_RAT UniProtKB/TrEMBL
  D4ADC2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-09 Helz2  helicase with zinc finger 2, transcriptional coactivator  Pric285  peroxisomal proliferator-activated receptor A interacting complex 285  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Pric285  peroxisomal proliferator-activated receptor A interacting complex 285  RGD1306056_predicted  similar to Peroxisomal proliferator-activated receptor A interacting complex 285 kDa protein (PPAR-alpha interacting complex protein 285) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306056_predicted  similar to Peroxisomal proliferator-activated receptor A interacting complex 285 kDa protein (PPAR-alpha interacting complex protein 285) (predicted)  LOC296474_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296474_predicted  similar to Peroxisomal proliferator-activated receptor A interacting complex 285 kDa protein (PPAR-alpha interacting complex protein 285) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL