Symbol:
Nup188
Name:
nucleoporin 188
RGD ID:
1306022
Description:
Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Predicted to be located in nuclear envelope. Predicted to be part of nuclear pore inner ring. Human ortholog(s) of this gene implicated in Sandestig-Stefanova syndrome and respiratory failure. Orthologous to human NUP188 (nucleoporin 188); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 2,4-dinitrotoluene; amphetamine; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC100911302; LOC366016; nucleoporin NUP188; nucleoporin NUP188 homolog
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
NUP188 (nucleoporin 188) RGD
RGD
Mus musculus (house mouse):
Nup188 (nucleoporin 188) RGD
RGD
Chinchilla lanigera (long-tailed chinchilla):
Nup188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
NUP188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
NUP188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Nup188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
NUP188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
NUP188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Nup188 (nucleoporin 188) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2) HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Nup188 (nucleoporin 188)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
NUP188 (nucleoporin 188)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
nup188 (nucleoporin 188)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Nup188
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
NUP188
Alliance
DIOPT (Hieranoid|PANTHER)
Xenopus tropicalis (tropical clawed frog):
nup188
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 33,957,778 - 34,014,122 (+) NCBI GRCr8 mRatBN7.2 3 13,559,917 - 13,616,313 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 13,559,990 - 13,616,307 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 3 8,852,271 - 8,908,608 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 8,873,933 - 8,908,438 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 14,205,251 - 14,261,382 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 9,331,812 - 9,388,204 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 3 8,326,493 - 8,382,816 (+) NCBI Celera Cytogenetic Map 3 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - KEGG (archival)
Nup188 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 33,957,778 - 34,014,122 (+) NCBI GRCr8 mRatBN7.2 3 13,559,917 - 13,616,313 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 13,559,990 - 13,616,307 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 3 8,852,271 - 8,908,608 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 8,873,933 - 8,908,438 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 14,205,251 - 14,261,382 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 9,331,812 - 9,388,204 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 3 8,326,493 - 8,382,816 (+) NCBI Celera Cytogenetic Map 3 p12 NCBI
NUP188 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 9 128,947,699 - 129,007,096 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 9 128,947,699 - 129,007,096 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 9 131,709,978 - 131,769,375 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 9 130,749,798 - 130,809,195 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 9 128,789,563 - 128,848,928 NCBI Celera 9 102,361,838 - 102,421,686 (+) NCBI Celera Cytogenetic Map 9 q34.11 NCBI HuRef 9 101,317,691 - 101,376,696 (+) NCBI HuRef CHM1_1 9 131,861,021 - 131,920,403 (+) NCBI CHM1_1 T2T-CHM13v2.0 9 141,151,108 - 141,210,530 (+) NCBI T2T-CHM13v2.0
Nup188 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 30,176,419 - 30,234,278 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 2 30,176,409 - 30,234,278 (+) Ensembl GRCm39 Ensembl GRCm38 2 30,286,407 - 30,344,266 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 30,286,397 - 30,344,266 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 30,141,953 - 30,199,782 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 2 30,108,442 - 30,166,271 (+) NCBI MGSCv36 mm8 Celera 2 29,991,190 - 30,049,297 (+) NCBI Celera Cytogenetic Map 2 B NCBI cM Map 2 21.49 NCBI
Nup188 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955570 1,312,998 - 1,369,513 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955570 1,312,998 - 1,369,513 (+) NCBI ChiLan1.0 ChiLan1.0
NUP188 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 11 10,346,228 - 10,404,809 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 9 10,348,576 - 10,407,139 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 9 100,069,656 - 100,130,521 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 9 128,733,749 - 128,791,252 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 9 128,733,780 - 128,791,252 (+) Ensembl panpan1.1 panPan2
NUP188 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 9 54,657,520 - 54,712,900 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 9 54,657,682 - 54,712,827 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 9 53,853,072 - 53,908,426 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 9 55,578,563 - 55,633,941 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 9 55,578,567 - 55,633,921 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 9 54,340,129 - 54,395,076 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 9 54,652,331 - 54,707,442 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 9 54,745,638 - 54,800,996 (-) NCBI UU_Cfam_GSD_1.0
Nup188 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404947 196,639,939 - 196,694,386 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936487 16,408,518 - 16,462,923 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936487 16,408,523 - 16,462,916 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
NUP188 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 1 269,259,519 - 269,312,862 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 1 269,259,496 - 269,312,872 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 1 303,275,625 - 303,328,996 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
NUP188 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 12 9,150,603 - 9,213,512 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 12 9,151,005 - 9,208,452 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666096 299,833 - 407,072 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Nup188 Naked Mole-Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HetGla_female_1.0 Ensembl NW_004624760 6,111,621 - 6,118,084 (-) Ensembl HetGla_female_1.0 HetGla_female_1.0 Ensembl hetGla2 HetGla_female_1.0 Ensembl NW_004624760 6,061,130 - 6,106,853 (-) Ensembl HetGla_female_1.0 HetGla_female_1.0 Ensembl hetGla2 HetGla 1.0 NW_004624760 6,061,130 - 6,120,597 (-) NCBI HetGla_female_1.0 HetGla 1.0 hetGla2
.
Predicted Target Of
Count of predictions: 83 Count of miRNA genes: 67 Interacting mature miRNAs: 79 Transcripts: ENSRNOT00000030996 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1558647 Cm46 Cardiac mass QTL 46 5.4 0.0000055 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 10778823 30356773 Rat 1358357 Srcrtb1 Stress Responsive Cort Basal QTL 1 6.36 0.002 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 8658162 27494778 Rat 6893355 Bw101 Body weight QTL 101 0.4 0.38 body mass (VT:0001259) body weight (CMO:0000012) 3 10778704 30357018 Rat 4889966 Bss95 Bone structure and strength QTL 95 4.4 tibia area (VT:1000281) tibia-fibula cross-sectional area (CMO:0001718) 3 1 36847613 Rat 1558654 Bw56 Body weight QTL 56 4.5 0.0000171 body mass (VT:0001259) body weight (CMO:0000012) 3 10778704 30357018 Rat 10401810 Kidm53 Kidney mass QTL 53 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 8227194 47233430 Rat 1298526 Arunc3 Aerobic running capacity QTL 3 2.2 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 3 8227194 33703538 Rat 8693641 Alc30 Alcohol consumption QTL 30 2 0.739 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 3 10434306 24512004 Rat 1558650 Cm48 Cardiac mass QTL 48 4 0.0001 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 3 10778823 30356773 Rat 1358905 Hrtrt17 Heart rate QTL 17 5.9 0.000014 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 3 10861912 89878372 Rat 70191 BpQTLcluster4 Blood pressure QTL cluster 4 3 arterial blood pressure trait (VT:2000000) absolute change in systolic blood pressure (CMO:0000607) 3 10778704 50302886 Rat 631545 Bp85 Blood pressure QTL 85 3.1 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 1 33278763 Rat 631679 Cm10 Cardiac mass QTL 10 7.34 0.0001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 1 31158234 Rat 2290452 Scl56 Serum cholesterol level QTL 56 2.26 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 3 1 91609953 Rat 1558657 Cm43 Cardiac mass QTL 43 6.6 3e-08 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 10778823 30356773 Rat 631568 Bp92 Blood pressure QTL 92 2.2 0.005 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 1 39874793 Rat 70203 Gcr2 Gastric cancer resistance QTL 2 2.6 stomach morphology trait (VT:0000470) stomach tumor susceptibility score (CMO:0002043) 3 8658162 27494778 Rat 6893363 Bw105 Body weight QTL 105 2.6 0.0036 body mass (VT:0001259) body weight (CMO:0000012) 3 10778704 30357018 Rat 70202 Alc19 Alcohol consumption QTL 19 2.5 drinking behavior trait (VT:0001422) ethanol intake volume to total fluid intake volume ratio (CMO:0001591) 3 1 27494778 Rat 2312664 Scl62 Serum cholesterol level QTL 62 0.05 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 3 1 38710544 Rat 61468 Bp15 Blood pressure QTL 15 4.4 blood pressure trait (VT:0000183) pulse pressure (CMO:0000292) 3 1 33278763 Rat 631831 Alc8 Alcohol consumption QTL 8 2.7 consumption behavior trait (VT:0002069) calculated ethanol drink intake rate (CMO:0001615) 3 1 33230976 Rat
RH129640
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 13,616,073 - 13,616,256 (+) MAPPER mRatBN7.2 Rnor_6.0 3 8,908,369 - 8,908,551 NCBI Rnor6.0 Rnor_5.0 3 14,261,143 - 14,261,325 UniSTS Rnor5.0 RGSC_v3.4 3 9,387,965 - 9,388,147 UniSTS RGSC3.4 Celera 3 8,382,577 - 8,382,759 UniSTS RH 3.4 Map 3 51.31 UniSTS Cytogenetic Map 3 p12 UniSTS
RH134009
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 13,616,943 - 13,617,144 (+) MAPPER mRatBN7.2 Rnor_6.0 3 8,909,239 - 8,909,439 NCBI Rnor6.0 Rnor_5.0 3 14,262,013 - 14,262,213 UniSTS Rnor5.0 RGSC_v3.4 3 9,388,835 - 9,389,035 UniSTS RGSC3.4 Celera 3 8,383,447 - 8,383,647 UniSTS Cytogenetic Map 3 p12 UniSTS
MARC_17455-17456:1028295191:1
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 13,590,331 - 13,591,009 (+) MAPPER mRatBN7.2 Rnor_6.0 3 8,882,657 - 8,883,334 NCBI Rnor6.0 Rnor_5.0 3 14,235,607 - 14,236,284 UniSTS Rnor5.0 RGSC_v3.4 3 9,362,143 - 9,362,820 UniSTS RGSC3.4 Celera 3 8,356,878 - 8,357,555 UniSTS Cytogenetic Map 3 p12 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000030996 ⟹ ENSRNOP00000032298
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 13,559,990 - 13,616,307 (+) Ensembl Rnor_6.0 Ensembl 3 8,873,933 - 8,908,438 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000099170 ⟹ ENSRNOP00000084918
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 13,559,990 - 13,616,304 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000102741 ⟹ ENSRNOP00000077884
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 13,559,990 - 13,577,592 (+) Ensembl
RefSeq Acc Id:
NM_001427655 ⟹ NP_001414584
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 33,957,812 - 34,014,122 (+) NCBI
RefSeq Acc Id:
XM_006233905 ⟹ XP_006233967
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 33,957,778 - 34,014,120 (+) NCBI mRatBN7.2 3 13,559,917 - 13,616,313 (+) NCBI Rnor_6.0 3 8,852,271 - 8,908,608 (+) NCBI Rnor_5.0 3 14,205,251 - 14,261,382 (+) NCBI
Sequence:
CCCCCGGTCTGGCGGCGCACGGTCACGTGGGTGCAGCGTATAGGGGCGGGGCTGGGACGCGCGCGCGAAGATGGCGGCTGCCGCCGGTGGGCCGTGTGTGAGGAGCAGTAGAGAACTCTGGACGATTC
hide sequence
RefSeq Acc Id:
XM_006233906 ⟹ XP_006233968
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 33,962,427 - 34,014,120 (+) NCBI mRatBN7.2 3 13,564,593 - 13,616,313 (+) NCBI Rnor_6.0 3 8,856,428 - 8,908,608 (+) NCBI Rnor_5.0 3 14,205,251 - 14,261,382 (+) NCBI
Sequence:
AACAAACTTAGTATGTGTCTGTGTATGAGGGAGCATGAGTGCCGTGTCATAGCTGGTGAGCAGAAGACACATCCAAGTCAGTCCTTCTGCTCTACAGTCAGGCTGAACACGGCTTGCAAGGCTTGTGC
hide sequence
RefSeq Acc Id:
XM_039106780 ⟹ XP_038962708
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 33,957,778 - 34,008,021 (+) NCBI mRatBN7.2 3 13,559,917 - 13,610,198 (+) NCBI
RefSeq Acc Id:
XP_006233967 ⟸ XM_006233905
- Peptide Label:
isoform X1
- UniProtKB:
F1LRC6 (UniProtKB/TrEMBL), A6JTX0 (UniProtKB/TrEMBL)
- Sequence:
MAAAAGGPCVRSSRELWTILLGRSALRELNQIEAELNKHWQRLLEGLSYYRPPSPSSAERVKANKDVASPLKELGLRVSKFLGLDEEQSVQLLQCYLQEAYRGTRDSLKTVLQDERQSQALTLKIADY
hide sequence
RefSeq Acc Id:
XP_006233968 ⟸ XM_006233906
- Peptide Label:
isoform X2
- UniProtKB:
A6JTX0 (UniProtKB/TrEMBL)
- Sequence:
MHAPVHRSSRELWTILLGRSALRELNQIEAELNKHWQRLLEGLSYYRPPSPSSAERVKANKDVASPLKELGLRVSKFLGLDEEQSVQLLQCYLQEAYRGTRDSLKTVLQDERQSQALTLKIADYYYEE
hide sequence
Ensembl Acc Id:
ENSRNOP00000032298 ⟸ ENSRNOT00000030996
RefSeq Acc Id:
XP_038962708 ⟸ XM_039106780
- Peptide Label:
isoform X3
Ensembl Acc Id:
ENSRNOP00000077884 ⟸ ENSRNOT00000102741
Ensembl Acc Id:
ENSRNOP00000084918 ⟸ ENSRNOT00000099170
RefSeq Acc Id:
NP_001414584 ⟸ NM_001427655
- UniProtKB:
A6JTX0 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2021-03-09
Nup188
nucleoporin 188
LOC100911302
nucleoporin NUP188 homolog
Data merged from RGD:6494074
737654 PROVISIONAL
2012-07-05
LOC100911302
nucleoporin NUP188 homolog
Symbol and Name status set to provisional
70820 PROVISIONAL
2005-12-06
Nup188
nucleoporin 188
Nup188_predicted
nucleoporin 188 (predicted)
Symbol and Name updated
1559027 APPROVED
2005-01-12
Nup188_predicted
nucleoporin 188 (predicted)
Symbol and Name status set to approved
70820 APPROVED
