Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Asphd2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ASPHD2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Asphd2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ASPHD2 mRNA] | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | Asphd2 (Mus musculus) | 6480464 | Estradiol results in increased expression of ASPHD2 mRNA | CTD | PMID:19484750 | 17beta-estradiol | multiple interactions | ISO | ASPHD2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of ASPHD2 mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of ASPHD2 mRNA | CTD | PMID:20660070 and PMID:30165855 | 2-hydroxypropanoic acid | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ASPHD2 mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Asphd2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of ASPHD2 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Asphd2 (Mus musculus) | 6480464 | bisphenol S affects the methylation of ASPHD2 gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ASPHD2 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ASPHD2 mRNA | CTD | PMID:24780913 | aflatoxin B1 | affects expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ASPHD2 protein | CTD | PMID:20106945 | aflatoxin B1 | affects methylation | ISO | ASPHD2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of ASPHD2 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | ASPHD2 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ASPHD2 intron | CTD | PMID:30157460 | aflatoxin M1 | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Aflatoxin M1 results in increased expression of ASPHD2 mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ASPHD2 mRNA | CTD | PMID:21934132 | antirheumatic drug | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ASPHD2 mRNA | CTD | PMID:24449571 | avobenzone | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | avobenzone results in decreased expression of ASPHD2 mRNA | CTD | PMID:31016361 | benzo[a]pyrene | increases methylation | ISO | ASPHD2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ASPHD2 5' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ASPHD2 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ASPHD2 mRNA | CTD | PMID:36041667 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ASPHD2 mRNA | CTD | PMID:34947998 | bisphenol A | decreases methylation | ISO | Asphd2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of ASPHD2 promoter | CTD | PMID:27312807 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ASPHD2 mRNA | CTD | PMID:36041667 | butanal | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ASPHD2 mRNA | CTD | PMID:26079696 | cadmium atom | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Cadmium results in increased expression of ASPHD2 mRNA | CTD | PMID:24376830 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ASPHD2 mRNA | CTD | PMID:33453195 | chlorpyrifos | decreases expression | ISO | Asphd2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ASPHD2 mRNA | CTD | PMID:37019170 | clobetasol | increases expression | ISO | Asphd2 (Mus musculus) | 6480464 | Clobetasol results in increased expression of ASPHD2 mRNA | CTD | PMID:27462272 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of ASPHD2 mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ASPHD2 mRNA | CTD | PMID:20106945 | dorsomorphin | multiple interactions | ISO | ASPHD2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | ethyl methanesulfonate | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of ASPHD2 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | ISO | Asphd2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ASPHD2 mRNA] | CTD | PMID:22206623 | lead(0) | affects expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Lead affects the expression of ASPHD2 mRNA | CTD | PMID:22313790 | methyl methanesulfonate | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ASPHD2 mRNA | CTD | PMID:23649840 | nickel atom | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Nickel results in increased expression of ASPHD2 mRNA | CTD | PMID:24768652 and PMID:25583101 | paracetamol | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ASPHD2 mRNA | CTD | PMID:29067470 | pentanal | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | pentanal results in increased expression of ASPHD2 mRNA | CTD | PMID:26079696 | perfluorooctanoic acid | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of ASPHD2 mRNA | CTD | PMID:36326898 | phenylmercury acetate | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of ASPHD2 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | ASPHD2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ASPHD2 mRNA | CTD | PMID:27188386 | progesterone | multiple interactions | ISO | ASPHD2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of ASPHD2 mRNA | CTD | PMID:20660070 | propanal | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of ASPHD2 mRNA | CTD | PMID:26079696 | rac-lactic acid | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ASPHD2 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | ASPHD2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ASPHD2 mRNA | CTD | PMID:19281266 | temozolomide | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ASPHD2 mRNA | CTD | PMID:31758290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of ASPHD2 gene | CTD | PMID:27618143 | trichostatin A | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ASPHD2 mRNA | CTD | PMID:24935251 | trichostatin A | multiple interactions | ISO | ASPHD2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ASPHD2 mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ASPHD2 mRNA | CTD | PMID:24935251 and PMID:26272509 | triptonide | increases expression | ISO | Asphd2 (Mus musculus) | 6480464 | triptonide results in increased expression of ASPHD2 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | ASPHD2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ASPHD2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | Asphd2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ASPHD2 mRNA | CTD | PMID:17963808 | valproic acid | increases expression | ISO | Asphd2 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ASPHD2 mRNA | CTD | PMID:21427059 | valproic acid | affects expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ASPHD2 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ASPHD2 mRNA | CTD | PMID:23179753 more ... | zoledronic acid | decreases expression | ISO | ASPHD2 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of ASPHD2 mRNA | CTD | PMID:24714768 | |